March 2021 PMID 33654105

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data.

Matthias Zunhammer, Tamás Spisák, Tor D Wager, Ulrike Bingel

Mentions

80
Peak: 30 in Mar 2021
across 5 sources since Mar 2021

Extended reach

187,336
potential audience

Total likes

42

Video views

3

Mentions per month

Mar 2021 – Oct 2025

Where it's discussed

  • X / Twitter40 posts
  • News30 articles
  • Blogs5 articles
  • Reddit3 posts
  • YouTube2 videos

AI synopsis

What people are saying

Many posts demonstrate genuine interest and respect for the publication, with phrases like 'fantastic group effort,' 'always interesting,' and 'insightful' revealing a tone of admiration and curiosity. The choice of words emphasizes the study's significance and the collaborative nature of the research, contributing to a perception of moderate impact primarily within neuroscience and medical research contexts.

AgreementModerate agreement

Most discussions acknowledge the significance of the meta-analysis and recognize its contributions to understanding placebo analgesia, with many expressing pride and appreciation for the research efforts.

InterestHigh interest

There is high curiosity and relevance, as evidenced by numerous posts highlighting the importance of the study and its connection to ongoing research projects.

EngagementHigh engagement

Several discussions reference specific aspects of the study, such as its neural findings and methodological rigor, indicating deep engagement with the material.

ImpactModerate impact

While the discussions underscore the study's importance within the scientific community, the focus remains on academic and research relevance rather than immediate real-world impact.

Abstract in brief

  • This study is a meta-analysis of fMRI research to understand how placebo treatments reduce pain, showing that placebo effects lead to decreases in activity in brain regions linked to attention and somatomotor functions.
  • The analysis reveals that smaller, widespread reductions in pain-related brain activity happen in areas like the midinsula and posterior insula, and these reductions are associated with actual placebo analgesic effects.
  • The findings also show increased activity in some frontoparietal regions, but with variation across different studies, indicating that placebo analgesia involves multiple brain mechanisms that can differ depending on the context.]

Top posts

Most liked on X and Bluesky
Bingel Laboratory (Bingellab)
@bingellab · X

@MZunhammer and @spisaktamas have published their study “Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data”. Thanks to @torwager and the Placebo Imaging Consortium for this fantastic group effort! https://t.co/7WizCHMpWt

Mar 3, 2021 · 15 likes · 7 shares · 615 followers View post →
SFB/TRR 289 Treatment Expectation
@sfb_trr289 · X

We are so happy and proud that our study "Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data" received >12,500 downloads since its publication in @NatureComms! The project is connected to our Z03 project: https://t.co/6T1fruidMQ

Jun 17, 2022 · 14 likes · 4 shares · 384 followers View post →
ResearchHub
@ResearchHub · X

Despite the widely-known therapeutic impact of the #placebo effect, little is known about its physiology Zunhammer et al. conducted a meta-analysis of fMRI studies to explore the neural correlates of this mysterious phenomenon https://t.co/NbJSeHnx9H https://t.co/y3Dxcztt3V

Mar 8, 2021 · 3 likes · 1 share · 43,068 followers View post →
New neuroscience papers in Nature Communications
@NeuroPaperBot · X

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data https://t.co/TUMcEIuoHo

Mar 2, 2021 · 3 likes · 2 shares · 1,955 followers View post →
ppoisbeau
@ppoisbeau · X

Zunhammer et al (Nat Comm, 2021) "The brain systems underlying placebo analgesia are still insufficiently understood" but always interesting to have this one : Meta-analysis of neural systems underlying placebo analgesia... https://t.co/0sFHW8Tr4c

Mar 3, 2021 · 3 likes · 1 share · 365 followers View post →
Paul McCullough
@ThePostsynaptic · X

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data https://t.co/51IYiH7xea https://t.co/nMt0fEDPzD

Mar 3, 2021 · 1 like · 2 shares · 2,586 followers View post →

All mentions

Stephan Geuter
@stephangeuter · X

RT @sfb_trr289: We are so happy and proud that our study "Meta-analysis of neural systems underlying placebo analgesia from individual part…

Jun 17, 2022 · 4 shares · 183 followers View post →
Society for Interdisciplinary Placebo Studies
@SIPSplacebo · X

RT @sfb_trr289: We are so happy and proud that our study "Meta-analysis of neural systems underlying placebo analgesia from individual part…

Jun 17, 2022 · 4 shares · 700 followers View post →
Dr. Helena Hartmann
@helenahhartmann · X

RT @sfb_trr289: We are so happy and proud that our study "Meta-analysis of neural systems underlying placebo analgesia from individual part…

Jun 17, 2022 · 4 shares · 7,998 followers View post →
Bingel Laboratory (Bingellab)
@bingellab · X

RT @sfb_trr289: We are so happy and proud that our study "Meta-analysis of neural systems underlying placebo analgesia from individual part…

Jun 17, 2022 · 4 shares · 615 followers View post →
SFB/TRR 289 Treatment Expectation
@sfb_trr289 · X

We are so happy and proud that our study "Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data" received >12,500 downloads since its publication in @NatureComms! The project is connected to our Z03 project: https://t.co/6T1fruidMQ

Jun 17, 2022 · 14 likes · 4 shares · 384 followers View post →
Éric Maeker
@DrMaeker · X

RT @AgingPapers:

Jul 5, 2021 · 1 share · 2,608 followers View post →
AgingPapers
@AgingPapers · X

Jul 4, 2021 · 1 share · 184 followers View post →
Éric Maeker
@DrMaeker · X

RT @AgingPapers:

Jun 6, 2021 · 2 shares · 2,608 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @AgingPapers:

Jun 6, 2021 · 2 shares · 6,703 followers View post →
AgingPapers
@AgingPapers · X

Jun 6, 2021 · 1 like · 2 shares · 184 followers View post →
Éric Maeker
@DrMaeker · X

RT @AgingPapers:

Mar 11, 2021 · 1 share · 2,608 followers View post →
AgingPapers
@AgingPapers · X

Mar 11, 2021 · 1 share · 184 followers View post →
Vitaly Zviagin
@Dr_VitalyZ · X

RT @ResearchHub: Despite the widely-known therapeutic impact of the #placebo effect, little is known about its physiology Zunhammer et al…

Mar 9, 2021 · 1 share · 7 followers View post →
ResearchHub
@ResearchHub · X

Despite the widely-known therapeutic impact of the #placebo effect, little is known about its physiology Zunhammer et al. conducted a meta-analysis of fMRI studies to explore the neural correlates of this mysterious phenomenon https://t.co/NbJSeHnx9H https://t.co/y3Dxcztt3V

Mar 8, 2021 · 3 likes · 1 share · 43,068 followers View post →
Masa Yamamoto予測誤差が大きい人生を楽しもう
@mshero_y · X

RT @rinatie_ceo: Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data @nature https://t.co/jT…

Mar 8, 2021 · 2 shares · 1,067 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @rinatie_ceo: Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data @nature https://t.co/jT…

Mar 8, 2021 · 2 shares · 6,703 followers View post →
Rina Saltman
@rinatie_ceo · X

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data @nature https://t.co/jTV1WFw43A

Mar 8, 2021 · 2 shares · 3,559 followers View post →
Éric Maeker
@DrMaeker · X

RT @AgingPapers:

Mar 7, 2021 · 1 share · 2,608 followers View post →
AgingPapers
@AgingPapers · X

Mar 7, 2021 · 1 share · 184 followers View post →
Marcia Petyt
@marcia_petyt · X

RT @ThePostsynaptic: Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data https://t.co/51IYiH…

Mar 6, 2021 · 2 shares · 986 followers View post →
Dan-Mikael Ellingsen
@dmellingsen · X

RT @bingellab: @MZunhammer and @spisaktamas have published their study “Meta-analysis of neural systems underlying placebo analgesia from i…

Mar 5, 2021 · 7 shares · 568 followers View post →
Michael Dow
@docmike8 · X

RT @bingellab: @MZunhammer and @spisaktamas have published their study “Meta-analysis of neural systems underlying placebo analgesia from i…

Mar 4, 2021 · 7 shares · 331 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @ThePostsynaptic: Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data https://t.co/51IYiH…

Mar 3, 2021 · 2 shares · 6,703 followers View post →
Paul McCullough
@ThePostsynaptic · X

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data https://t.co/51IYiH7xea https://t.co/nMt0fEDPzD

Mar 3, 2021 · 1 like · 2 shares · 2,586 followers View post →
Katharina Schmidt
@KathSchmidt5 · X

RT @bingellab: @MZunhammer and @spisaktamas have published their study “Meta-analysis of neural systems underlying placebo analgesia from i…

Mar 3, 2021 · 7 shares · 114 followers View post →
Dr. Helena Hartmann
@helenahhartmann · X

RT @bingellab: @MZunhammer and @spisaktamas have published their study “Meta-analysis of neural systems underlying placebo analgesia from i…

Mar 3, 2021 · 7 shares · 7,998 followers View post →
Giacomo Rossettini
@GiacomoRoss86 · X

RT @bingellab: @MZunhammer and @spisaktamas have published their study “Meta-analysis of neural systems underlying placebo analgesia from i…

Mar 3, 2021 · 7 shares · 2,883 followers View post →
tor wager
@torwager · X

RT @bingellab: @MZunhammer and @spisaktamas have published their study “Meta-analysis of neural systems underlying placebo analgesia from i…

Mar 3, 2021 · 7 shares · 9,511 followers View post →
ppoisbeau
@ppoisbeau · X

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data https://t.co/0sFHW8Tr4c

Mar 3, 2021 · 1 like · 365 followers View post →
Clovis Varangot-Reille
@ClovisReille · X

RT @ppoisbeau: Zunhammer et al (Nat Comm, 2021) "The brain systems underlying placebo analgesia are still insufficiently understood" but al…

Mar 3, 2021 · 1 share · 130 followers View post →
815wrldtrvlr
@815wrldtrvlr · X

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data | Nature Communications https://t.co/zNM8PD2oO7

Mar 3, 2021 · 36,629 followers View post →
ppoisbeau
@ppoisbeau · X

Zunhammer et al (Nat Comm, 2021) "The brain systems underlying placebo analgesia are still insufficiently understood" but always interesting to have this one : Meta-analysis of neural systems underlying placebo analgesia... https://t.co/0sFHW8Tr4c

Mar 3, 2021 · 3 likes · 1 share · 365 followers View post →
Stefanie Brassen @stefaniebrassen.bsky.social
@StefanieBrassen · X

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data https://t.co/MB4LAZIUQE

Mar 3, 2021 · 1 like · 473 followers View post →
Bingel Laboratory (Bingellab)
@bingellab · X

@MZunhammer and @spisaktamas have published their study “Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data”. Thanks to @torwager and the Placebo Imaging Consortium for this fantastic group effort! https://t.co/7WizCHMpWt

Mar 3, 2021 · 15 likes · 7 shares · 615 followers View post →
Dr. Stuart Fischer
@TheFitDr · X

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data | Nature Communications https://t.co/o3C3Peo22G

Mar 3, 2021 · 1 share · 17,514 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @AMAinsight: Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data | Nature Communications…

Mar 2, 2021 · 1 share · 6,703 followers View post →
Dr Anthony Martin
@AMAinsight · X

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data | Nature Communications https://t.co/ZifPBAnKXU

Mar 2, 2021 · 1 share · 913 followers View post →
Patricia Garrido
@PatriGarri14 · X

RT @NeuroPaperBot: Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data https://t.co/TUMcEIuo…

Mar 2, 2021 · 2 shares · 921 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @NeuroPaperBot: Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data https://t.co/TUMcEIuo…

Mar 2, 2021 · 2 shares · 6,703 followers View post →
New neuroscience papers in Nature Communications
@NeuroPaperBot · X

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data https://t.co/TUMcEIuoHo

Mar 2, 2021 · 3 likes · 2 shares · 1,955 followers View post →