In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with slightly elevated TC. https://t.co/ZWkK0yJogC https://t.co/AyqZFpkLid
A nonlinear association of total cholesterol with all-cause and cause-specific mortality.
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Mar 2021 – Aug 2025Where it's discussed
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X / Twitter37 posts
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YouTube4 videos
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What people are saying
The collection of posts exemplifies a mix of curiosity and cautious agreement, with several commenters referencing the nonlinear relationship between cholesterol levels and mortality, such as mentions that levels below 120 mg/dL are linked to higher death risks or that levels around 200 mg/dL are potentially healthier. The use of phrases like 'interesting' and references to ongoing scientific debates reflect a thoughtful engagement, emphasizing the complexity and evolving understanding of cholesterol's role in health.
Most posts seem to acknowledge the complexity of cholesterol's relationship with mortality, with some highlighting that both low and high levels pose risks, reflecting moderate approval of the article's findings.
The discussions show notable curiosity, with multiple commenters referencing specific cholesterol levels and implications, indicating strong engagement and relevance.
Participants mention aspects such as previous studies, biological mechanisms, and potential implications, demonstrating a moderate depth of engagement beyond surface reactions.
While some posts suggest that the study may influence how cholesterol is viewed in health discussions, the overall tone indicates a cautious perception of the immediate significance, rather than a breakthrough assertion.
Abstract in brief
- The study found that total cholesterol (TC) has a complex, nonlinear relationship with mortality, showing a U-shaped pattern where both very low and very high TC levels are associated with increased risk of death from all causes, cardiovascular disease (CVD), and cancer.
- Specifically, lower TC levels (around 120 mg/dL) are linked to increased all-cause and cancer mortality, while higher TC levels (around 280 mg/dL) are associated with increased CVD and cancer mortality, indicating both ends of the spectrum pose risks.
- Overall, the results suggest that maintaining TC within an optimal range is important for reducing mortality risk, as both very low and very high levels are linked to poorer survival outcomes.
Top posts
Most liked on X and BlueskyEl colesterol, ni demasiado alto ni demasiado bajo. https://t.co/z8UqB5Dprg https://t.co/SW9RcgfWNL
TC < 120 mg/dL was strongly predictive of death risk from all causes, whereas TC ≥ 280 was not, except to CVD mortality. https://t.co/tCp4N1LtvA
"A nonlinear association of total cholesterol with all-cause and cause-specifc mortality" - https://t.co/2MISpyTvid "A TC range of <200 mg/dL was strongly linked to a higher risk of death from all causes, as well as cancer." https://t.co/6CS2jDNmRF
@FyodorOnegin But Peat didn't cite that study to my knowledge, and this survey found similar results. https://t.co/qosXqk69BG It's common for studies to speculate on ways the established dogma can be salvaged from conflicting results as scientific authors don't want to compromise their
This one found a nonlinear association of total cholesterol with all-cause and specific-cause mortality, with the optimal cut-off values depending on age, race, sex and lipid-lowering drugs use. https://t.co/s1TRsWni1h
All mentions
Examining Cholesterol's Impact on Mortality in the Elderly
This video explores the relationship between serum total cholesterol and mortality rates, particularly focusing on cardiovascular and non-cardiovascular causes in elderly populations. Dive into findings from various…
Reevaluating Statins: Limitations of Snapshot Statistics and an Alternative Approach
This video discusses the use of snapshot statistics in assessing statin use and explores an alternative method for determining their appropriateness. It emphasizes the complex relationship between cholesterol levels and…
Cholesterol, Eggs, and Heart Disease: New Insights on Health Risks
In this video, we investigate common myths and truths about eggs, cholesterol, and heart disease. We highlight the role of nutrition, lifestyle, and low-density lipoprotein cholesterol in cardiovascular health…
Examining Cholesterol's Role in Heart Disease and Mortality Rates
In this video, we explore myths and truths about cholesterol and its link to heart disease. We highlight key findings on low-density lipoprotein cholesterol and its impact on mortality rates, addressing risk factors…
@NikoHeikkala @HarriLehtimaki Kokonaiskolesteroli 5.5 mmol/litra tosiaan korreloi alimpaan kuolleisuuteen (NHANES). Mutta kardiovaskulaarinen kuolleisuus kuitenkin on koholla esimerkiksi jos kokonaiskolesteroli on 7 mmol/litra. https://t.co/GVHdjJVZov https://t.co/ymNXQgrpwf
@FyodorOnegin But Peat didn't cite that study to my knowledge, and this survey found similar results. https://t.co/qosXqk69BG It's common for studies to speculate on ways the established dogma can be salvaged from conflicting results as scientific authors don't want to compromise their
@Sandy18981238 @docisa33 Et même pour le cholestérol la science évolue https://t.co/gU7Oh0sfTu
@LenaandLucy Here’s a link to the study: https://t.co/j0eMwpW4XH
@MohammedAlo Please comment on this study. Low cholesterol shows an increase in all cause mortality. The levels they discuss are interesting. https://t.co/1BnIdhD505
@JanMetal2 @realtek12345 @MikolajPisarski https://t.co/XpNRs9a87S
@centerepublican @kevinburch @DrAlanDesmond Btw, "however, a TC range of < 200 mg/dL was strongly linked to a higher risk of death from all causes, as well as cancer" a cholesterol level between 200-250 is actually healthier. But few studies measure all cause mortality. https://t.co/FOYgSZGRPf
@TomaszLaszcz @MOstrega https://t.co/ONsz4u10ns
A nonlinear association of total cholesterol with all-cause and cause-specific mortality https://t.co/VucoMGpt6r This presents what Yuri Granik calls, The "Main Cholesterol Dilemma" Nutr Metab (Lond). 2021 Mar 10.
@CornivoreA @DrNadolsky https://t.co/5DHiB7U82X
@CornivoreA @DrNadolsky https://t.co/5DHiB7U82X Again, where do you fall on this chart?
RT @Blagosklonny: TC < 120 mg/dL was strongly predictive of death risk from all causes, whereas TC ≥ 280 was not, except to CVD mortali…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: TC < 120 mg/dL was strongly predictive of death risk from all causes, whereas TC ≥ 280 was not, except to CVD mortali…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with…
RT @Blagosklonny: TC < 120 mg/dL was strongly predictive of death risk from all causes, whereas TC ≥ 280 was not, except to CVD mortali…
TC < 120 mg/dL was strongly predictive of death risk from all causes, whereas TC ≥ 280 was not, except to CVD mortality. https://t.co/tCp4N1LtvA
In the Americans too “normal” total cholesterol (TC) levels (< 200) is associated with increased mortality compared with slightly elevated TC. https://t.co/ZWkK0yJogC https://t.co/AyqZFpkLid
RT @ZahcM: "A nonlinear association of total cholesterol with all-cause and cause-specifc mortality" - https://t.co/2MISpyTvid "A TC range…
RT @ZahcM: "A nonlinear association of total cholesterol with all-cause and cause-specifc mortality" - https://t.co/2MISpyTvid "A TC range…
RT @ZahcM: "A nonlinear association of total cholesterol with all-cause and cause-specifc mortality" - https://t.co/2MISpyTvid "A TC range…
"A nonlinear association of total cholesterol with all-cause and cause-specifc mortality" - https://t.co/2MISpyTvid "A TC range of <200 mg/dL was strongly linked to a higher risk of death from all causes, as well as cancer." https://t.co/6CS2jDNmRF
RT @nick_krontiris: This one found a nonlinear association of total cholesterol with all-cause and specific-cause mortality, with the optim…
A nonlinear association of total cholesterol with all-cause and cause-specific mortality (open access) https://t.co/uA92S39DHm #cholesterol #CVD #cancer #longevity
This one found a nonlinear association of total cholesterol with all-cause and specific-cause mortality, with the optimal cut-off values depending on age, race, sex and lipid-lowering drugs use. https://t.co/s1TRsWni1h
RT @IberianCitizen: El colesterol, ni demasiado alto ni demasiado bajo. https://t.co/z8UqB5Dprg https://t.co/SW9RcgfWNL
El colesterol, ni demasiado alto ni demasiado bajo. https://t.co/z8UqB5Dprg https://t.co/SW9RcgfWNL