PubHawk
June 2021 PMID 33711169

Methylenedioxymethamphetamine (MDMA): Serotonergic and dopaminergic mechanisms related to its use and misuse.

Susan Schenk, Quenten Highgate

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Mentions

9
Peak: 2 in Mar 2021
across 4 sources since Mar 2021

Extended reach

679,985
potential audience

Total likes

4,415

Video views

673,794

Mentions per month

Mar 2021 – Apr 2025

Where it's discussed

  • X / Twitter3 posts
  • YouTube2 videos
  • News2 articles
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reflect basic recognition of the publication, exemplified by posts that just retweet or state the article title without much elaboration. The tone remains neutral and informational, with little indication of strong opinions or detailed engagement, resulting in modest scores across all dimensions.

AgreementNeither agree nor disagree

The posts primarily acknowledge the publication but do not express strong support or disagreement, focusing mostly on sharing the topic.

InterestModerate interest

The posts demonstrate a moderate level of curiosity, as they briefly mention the mechanisms involved without delving deeply.

EngagementNeutral engagement

The discussions are minimal, mostly sharing the publication's title without further analysis or reflection.

ImpactNeutral impact

The posts have limited influence, mainly serving as references rather than provoking extensive debate or change.

Abstract in brief

  • MDMA mainly increases serotonin (5HT) with smaller effects on dopamine (DA), and the ratio of these increases influences its potential for abuse.
  • Repeated MDMA use can cause changes in brain chemistry related to both 5HT and DA, which may contribute to drug self-administration and substance use disorders.
  • Research shows that serotonin inhibits the initial drug-taking behavior, while dopamine is critical for maintaining ongoing MDMA use, with specific brain circuits and receptors involved in this modulation.
Read the full abstract

Top posts

Most liked on X and Bluesky
Views on Drugs
@ViewsOnDrugsBot · X

RT @ViewsOnDrugsBot: Methylenedioxymethamphetamine (#MDMA): #Serotonergic and #dopaminergic mechanisms related to its use and misuse https:…

Jul 11, 2021 · 2 shares · 2,060 followers View post →
Views on Drugs
@ViewsOnDrugsBot · X

RT @drugSciBot: Methylenedioxymethamphetamine (#MDMA): #Serotonergic and #dopaminergic mechanisms related to its use and misuse https://t.c…

Mar 26, 2021 · 2 shares · 2,060 followers View post →

All mentions

Views on Drugs
@ViewsOnDrugsBot · X

RT @ViewsOnDrugsBot: Methylenedioxymethamphetamine (#MDMA): #Serotonergic and #dopaminergic mechanisms related to its use and misuse https:…

Jul 11, 2021 · 2 shares · 2,060 followers View post →
Views on Drugs
@ViewsOnDrugsBot · X

RT @drugSciBot: Methylenedioxymethamphetamine (#MDMA): #Serotonergic and #dopaminergic mechanisms related to its use and misuse https://t.c…

Mar 26, 2021 · 2 shares · 2,060 followers View post →
Views on Drugs
@ViewsOnDrugsBot · X

Methylenedioxymethamphetamine (#MDMA): #Serotonergic and #dopaminergic mechanisms related to its use and misuse https://t.co/rkeQnQDASX

Mar 26, 2021 · 2 shares · 2,060 followers View post →