JAMA Neurol June 2021 PMID 33739362

Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis.

Amber Salter, Robert J Fox, Scott D Newsome, June Halper, David K B Li, Pamela Kanellis, Kathleen Costello, Bruce Bebo, Kottil Rammohan, Gary R Cutter, Anne H Cross

Mentions

79
Peak: 30 in Mar 2021
across 5 sources since Mar 2021

Extended reach

475,915
potential audience

Total likes

62

Video views

32

Mentions per month

Mar 2021 – Jul 2024

Where it's discussed

  • X / Twitter45 posts
  • News24 articles
  • Facebook5 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

Discussions express strong agreement, citing data on risk factors such as older age, MS disability, and race, with posts emphasizing the importance of monitoring high-risk groups. The tone is analytical and focused, with examples like the mention that nonambulatory patients face worse outcomes, and references to how treatments and comorbidities affect severity, reflecting deep engagement and perceived high impact.

AgreementModerate agreement

Most posts acknowledge and support the findings, emphasizing known risk factors like age and disability.

InterestHigh interest

Discussions show strong interest, highlighting points like the impact of different MS treatments and racial factors.

EngagementHigh engagement

Posts deeply engage by citing specific data points, referencing other research, and analyzing implications.

ImpactHigh impact

The discussions suggest the article guides clinical considerations and risk assessments, indicating significant influence.

Abstract in brief

  • The study analyzed data from over 1,600 North American patients with multiple sclerosis (MS) who also contracted COVID-19, finding that most had confirmed SARS-CoV-2 infection and varied from mild to severe outcomes, including hospitalization and death.
  • Key risk factors linked to more severe COVID-19 outcomes in MS patients included older age and the presence of comorbidities, as well as ambulatory disability, which increased the chances of hospitalization and other severe clinical levels.
  • The overall mortality rate among these patients was approximately 3.3%, highlighting the heightened vulnerability of individuals with MS—especially those with disabilities or additional health conditions—to severe COVID-19 complications.]

Top posts

Most liked on X and Bluesky
JAMA Neurology
@JAMANeuro · X

Older age and ambulatory disability, in addition to other risk factors, were associated with poor outcome in patients with #multiplesclerosis and #COVID19 in the COViMS Registry https://t.co/6TfhJL2KKc #MSCOVID19

Mar 19, 2021 · 9 likes · 3 shares · 65,092 followers View post →
WashU Medicine Neurology
@WashUNeurology · X

Anne Cross, MD, Amber Salter, MPH, PhD & their North American colleagues published "Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis" March 19 in @JAMANeuro. https://t.co/SoxuTiNgKT

Mar 23, 2021 · 9 likes · 2 shares · 2,782 followers View post →
Dr. Mona Marwan Alkhawajah د. منى مروان الخواجه
@monamarwan · X

SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis https://t.co/1X6iyXT3e9 via @JAMANeuro part of @JAMANetwork

Mar 20, 2021 · 7 likes · 1 share · 14,788 followers View post →
Neurology Today
@NeurologyToday · X

.@JAMANeuro: These data on North American pts w/ #COVID19 infection and #multiplesclerosis showed that both nonambulatory and ambulatory disability were independently related to an increased odds of poor clinical severity levels.#NeuroTwitter #MSAwareness https://t.co/XBCuYwfDI0 https://t.co/BQjzPVaXsE

Mar 29, 2021 · 5 likes · 3 shares · 64,836 followers View post →
Aaron Boster MD
@AaronBosterMD · X

Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis - PubMed https://t.co/yHUoBXSG8C

Mar 20, 2021 · 4 likes · 13,109 followers View post →
Patricia Mulero
@pamuca84 · X

Risk Factors Associated With #Covid19 in #MS patients: 1- high disability, 2-age, 3-Black race, 4-cardiovascular comorbidities and 5-recent GCT https://t.co/RBqIXoUNtd

Mar 20, 2021 · 4 likes · 2 shares · 658 followers View post →

All mentions

Barry Singer MD
@drbarrysinger · X

RT @drbarrysinger: @AaronBosterMD #COVID19 risks for people living with #MS on treatment is a concern. Some data suggests B-cell depleting…

Dec 8, 2021 · 1 share · 7,719 followers View post →
Barry Singer MD
@drbarrysinger · X

@AaronBosterMD #COVID19 risks for people living with #MS on treatment is a concern. Some data suggests B-cell depleting therapy may pose a higher risk of severe COVID-19 while interferon therapy may be safer. https://t.co/L2F9V3RNbi https://t.co/c1RNjAOOh9 Thoughts? @myelinMD @DrJim4MS #MSforum

Dec 8, 2021 · 3 likes · 1 share · 7,719 followers View post →
Paul Hepden
@PHepden · X

RT @ms_cme: 5) MS disability is independently assoc'd with worse clinical severity including death from COVID-19. Other risk factors for po…

Oct 4, 2021 · 1 share · 1,054 followers View post →
MultipleSclerosis_CME
@ms_cme · X

5) MS disability is independently assoc'd with worse clinical severity including death from COVID-19. Other risk factors for poor outcomes include black race, cardiovascular comorbidities, and recent treatment with steroids. #GetVaccinatedASAP doi: 10.1001/jamaneurol.2021.0688 https://t.co/3agk0QYq8B

Oct 4, 2021 · 4 likes · 1 share · 384 followers View post →
JAMA Neurology
@JAMANeuro · X

Older age and ambulatory disability, in addition to other risk factors, were associated with poor outcome in patients with #multiplesclerosis and #COVID19 in the COViMS Registry https://t.co/BgZB6ndfgY #MSCOVID19

Jun 23, 2021 · 3 likes · 65,092 followers View post →
Carta Healthcare
@Carta_AI · X

COViMS Registry data helped researchers quickly identify the risk factors for worse #COVID-19 clinical severity or death in patients with #multiplesclerosis, the knowledge that could help clinicians identify patients requiring more monitoring. https://t.co/wGJLuZfbSi

Jun 21, 2021 · 1 like · 110 followers View post →
Ped Neurology Briefs
@PedNeurBriefs · X

Pubmed: Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis https://t.co/1ze37MJQth

Jun 18, 2021 · 4,050 followers View post →
BrainSights iOS App
@BrainSightsApp · X

SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis - JAMA Neurology via BrainSights for iOS https://t.co/MAlgRTFY4Z

Jun 10, 2021 · 313 followers View post →
BrainSights iOS App
@BrainSightsApp · X

SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis - JAMA Neurology Jour. via BrainSights for iOS https://t.co/MAlgRTFY4Z

Jun 10, 2021 · 313 followers View post →
Matthew Brier
@MatthewBrier · X

RT @WashU_MSCenter: Outcomes and Risk Factors Associated With #SARSCoV2 #Infection in a North American Registry of Patients With #Multiple…

Jun 9, 2021 · 1 share · 124 followers View post →
WUSTLJohn L Trotter MS Center
@WashU_MSCenter · X

Outcomes and Risk Factors Associated With #SARSCoV2 #Infection in a North American Registry of Patients With #MultipleSclerosis @AnneHCross1 @BeboBruce @NMSSMI @WashUNeurology @WUSTLmed @JAMANeuro https://t.co/75O0mfTJCc

Jun 9, 2021 · 3 likes · 1 share · 117 followers View post →
ニューロドクター乱夢
@hichachu · X

Outcomes and risk factors associated with SARS-CoV-2 Infection in a North American registry of patients with multiple sclerosis https://t.co/lzZsstH0iq

May 21, 2021 · 4,261 followers View post →
Sue Strong
@strong_sue · X

Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis | Demyelinating Disorders | JAMA Neurology | JAMA Network

Apr 11, 2021 · 1,811 followers View post →
Gerald Businaro
@grbusinaro · X

Which factors predict worse COVID-19 outcomes in patients with MS? https://t.co/U1lHv0oe5s Shared from Epocrates, The #1 medical reference app. https://t.co/6B3jbzYYWk https://t.co/HVu9JusGih

Apr 5, 2021 · 5,226 followers View post →
Gerald Businaro
@grbusinaro · X

Which factors predict worse COVID-19 outcomes in patients with MS? https://t.co/U1lHv0oe5s Shared from Epocrates, The #1 medical reference app. https://t.co/6B3jbzYYWk https://t.co/gGASyP3bcS

Apr 4, 2021 · 5,226 followers View post →
Alejandro Jimenez
@AjimenezQ119 · X

RT @NeurologyToday: .@JAMANeuro: These data on North American pts w/ #COVID19 infection and #multiplesclerosis showed that both nonambulato…

Mar 29, 2021 · 3 shares · 148 followers View post →
CNHS
@CNH_Society · X

RT @NeurologyToday: .@JAMANeuro: These data on North American pts w/ #COVID19 infection and #multiplesclerosis showed that both nonambulato…

Mar 29, 2021 · 3 shares · 646 followers View post →
Neurology Today
@NeurologyToday · X

.@JAMANeuro: These data on North American pts w/ #COVID19 infection and #multiplesclerosis showed that both nonambulatory and ambulatory disability were independently related to an increased odds of poor clinical severity levels.#NeuroTwitter #MSAwareness https://t.co/XBCuYwfDI0 https://t.co/BQjzPVaXsE

Mar 29, 2021 · 5 likes · 3 shares · 64,836 followers View post →
Sonu Bhaskar
@DrSonuBhaskar · X

"Identification of risk factors key to "high risk" MS and #COVID19 patients - those who may require intense treatment and monitoring" #multiplesclerosis #SARSCoV2 @JAMANeuro https://t.co/FRSGUWVQdf via @JAMANeuro part of @JAMANetwork

Mar 25, 2021 · 11,671 followers View post →
Dr Mathieu Vokaer
@vokaer_md · X

Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis - PubMed https://t.co/sj0zhv5BkX

Mar 25, 2021 · 34 followers View post →
Roxana Flores A. MD,PhD
@flo_rox · X

RT @WashUNeurology: Anne Cross, MD, Amber Salter, MPH, PhD & their North American colleagues published "Outcomes and Risk Factors Associate…

Mar 24, 2021 · 2 shares · 2,151 followers View post →
JAMA Neurology
@JAMANeuro · X

RT @WashUNeurology: Anne Cross, MD, Amber Salter, MPH, PhD & their North American colleagues published "Outcomes and Risk Factors Associate…

Mar 24, 2021 · 2 shares · 65,092 followers View post →
Canadian Association For Biological Safety
@CABSACSB · X

https://t.co/n4v3eTnhNN

Mar 23, 2021 · 311 followers View post →
WashU Medicine Neurology
@WashUNeurology · X

Anne Cross, MD, Amber Salter, MPH, PhD & their North American colleagues published "Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis" March 19 in @JAMANeuro. https://t.co/SoxuTiNgKT

Mar 23, 2021 · 9 likes · 2 shares · 2,782 followers View post →
Dr. Brandon Beaber
@Brandon_Beaber · X

Association of age and race with outcome of COVID-19 in people with multiple sclerosis. https://t.co/6FE04sweQw https://t.co/ED18PTtkkd

Mar 22, 2021 · 3 likes · 18,242 followers View post →
Multiple Sclerosis
@myMStoday · X

https://t.co/Hz4oxlLyaK

Mar 22, 2021 · 2 likes · 12,589 followers View post →
CMSC
@mscare · X

In this registry-based cross-sectional study of 1626 North American patients with MS and COVID-19 infection was independently associated with increased odds of poor clinical severity levels after adjusting for other risk factors. https://t.co/SdT3PJEret

Mar 22, 2021 · 2 likes · 2,671 followers View post →
Observatorio del Dolor
@observadolor · X

Enlace al artículo completo

Mar 22, 2021 · 2,707 followers View post →
One Health, India
@One_Health_In · X

Check out this study on #COVID19 outcomes and risk factors in patients with multiple sclerosis (MS) @JAMANeuro https://t.co/ITRjN07BL0

Mar 22, 2021 · 1,029 followers View post →
BrainSights iOS App
@BrainSightsApp · X

SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis - JAMA Neurology via BrainSights for iOS https://t.co/MAlgRTFY4Z

Mar 21, 2021 · 313 followers View post →
Roxana Flores A. MD,PhD
@flo_rox · X

RT @monamarwan: SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis https://t.co/1X6iyXT3e9 via @JAMANeur…

Mar 20, 2021 · 1 share · 2,151 followers View post →
ALEM_MEDELLIN
@ALEM_Medellin · X

RT @pamuca84: Risk Factors Associated With #Covid19 in #MS patients: 1- high disability, 2-age, 3-Black race, 4-cardiovascular comorbiditi…

Mar 20, 2021 · 2 shares · 391 followers View post →
Dr. Mona Marwan Alkhawajah د. منى مروان الخواجه
@monamarwan · X

SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis https://t.co/1X6iyXT3e9 via @JAMANeuro part of @JAMANetwork

Mar 20, 2021 · 7 likes · 1 share · 14,788 followers View post →
Patología Desmielinizante_Valladolid
@Valladolid_EM · X

RT @pamuca84: Risk Factors Associated With #Covid19 in #MS patients: 1- high disability, 2-age, 3-Black race, 4-cardiovascular comorbiditi…

Mar 20, 2021 · 2 shares · 124 followers View post →
Patricia Mulero
@pamuca84 · X

Risk Factors Associated With #Covid19 in #MS patients: 1- high disability, 2-age, 3-Black race, 4-cardiovascular comorbidities and 5-recent GCT https://t.co/RBqIXoUNtd

Mar 20, 2021 · 4 likes · 2 shares · 658 followers View post →
Aaron Boster MD
@AaronBosterMD · X

Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis - PubMed https://t.co/yHUoBXSG8C

Mar 20, 2021 · 4 likes · 13,109 followers View post →
ニューロドクター乱夢
@hichachu · X

https://t.co/MlLz80PJ2O Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis 1626名の患者の内ほとんどが検査陽性SARS-CoV-2感染者(1345名[82.7%])、女性(1202名[74.0%])、再発寛解型MS(1255名[80.4%])。

Mar 20, 2021 · 2 likes · 4,261 followers View post →
Tal Givoly
@givoly · X

RT @aussiecoley: SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis https://t.co/qAHrzVVR3u via @JAMANeu…

Mar 19, 2021 · 2 shares · 2,649 followers View post →
Medivizor
@medivizor · X

RT @aussiecoley: SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis https://t.co/qAHrzVVR3u via @JAMANeu…

Mar 19, 2021 · 2 shares · 76,657 followers View post →
noel cole
@aussiecoley · X

SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis https://t.co/qAHrzVVR3u via @JAMANeuro part of @JAMANetwork

Mar 19, 2021 · 2 shares · 787 followers View post →
Karl C. Mayer
@Neuro24de · X

In dieser Register-basierten Querschnittsstudie von 1626 nordamerikanischen Patienten mit MS und COVID-19-Infektion war eine Gangstörung ein Hinweis auf einen schlechteren klinischen Verlauf. https://t.co/Auoqaj6qjO

Mar 19, 2021 · 1 like · 1,320 followers View post →
Roxana Flores A. MD,PhD
@flo_rox · X

RT @JAMANeuro: Older age and ambulatory disability, in addition to other risk factors, were associated with poor outcome in patients with #…

Mar 19, 2021 · 3 shares · 2,151 followers View post →
Marina A. Creed FNP-BC, APRN, MSCN
@MarinaC_Dyb · X

RT @JAMANeuro: Older age and ambulatory disability, in addition to other risk factors, were associated with poor outcome in patients with #…

Mar 19, 2021 · 3 shares · 1,778 followers View post →
JAMA Neurology
@JAMANeuro · X

Older age and ambulatory disability, in addition to other risk factors, were associated with poor outcome in patients with #multiplesclerosis and #COVID19 in the COViMS Registry https://t.co/6TfhJL2KKc #MSCOVID19

Mar 19, 2021 · 9 likes · 3 shares · 65,092 followers View post →
Pamela Kanellis
@PamelaKanellis · X

Outcomes and Risk Factors Associated With SARS-CoV-2 Infection in a North American Registry of Patients With Multiple Sclerosis https://t.co/zejsfhtFs7

Mar 19, 2021 · 1,139 followers View post →