Phytother Res July 2021 PMID 33751689

The effects of honey on pro- and anti-inflammatory cytokines: A narrative review.

Narges Navaei-Alipour, Mohadeseh Mastali, Gordon A Ferns, Maryam Saberi-Karimian, Majid Ghayour-Mobarhan

Mentions

20
Peak: 1 in Feb 2022
across 5 sources since Feb 2022

Extended reach

209,874
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Total likes

4,671

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205,730

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Feb 2022 – Nov 2025

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AI synopsis

What people are saying

The overall discussion appears minimal, with a focus on sharing a link rather than engaging with the article's content, such as the potential health effects of honey or its inconsistent evidence. The tone is neutral, reflecting curiosity rather than strong opinion or detailed analysis, highlighted by the brief call to check the link without additional commentary.

AgreementNeither agree nor disagree

The discussion does not show strong agreement or disagreement with the publication; it seems neutral or uncertain.

InterestModerate interest

There is modest interest indicated by a simple link share, but no detailed engagement or enthusiasm is evident.

EngagementNeutral engagement

The posts do not delve deeply into the content of the article, suggesting minimal critical analysis or detailed discussion.

ImpactNeutral impact

The sharing of the link alone implies limited perception of the publication's immediate significance or influence.

Abstract in brief

  • Honey contains antioxidants like flavonoids and phenolic acids that may support human health by reducing inflammation, but studies show inconsistent effects on wound healing and immunity.
  • Research indicates honey can decrease proinflammatory cytokines such as TNF, IL-6, and IL-1, while increasing anti-inflammatory cytokines like IL-10 in various conditions including cancer, neuroinflammatory disorders, liver injury, and gastric ulcers, mainly based on animal and in vitro studies.
  • There is limited evidence from human clinical trials, with only one randomized controlled trial mentioning honey's effects on inflammatory markers, and variations in honey types and sources are a limitation for reproducibility and definitive conclusions.

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