August 2022 PMID 33759701

Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Rating of Perceived Exertion and Fatigue in Trained Young Adults.

Avery Pakulak, Darren G Candow, Julia Totosy de Zepetnek, Scott C Forbes, Daniele Basta

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Mentions

34
Peak: 18 in Apr 2021
across 4 sources since Mar 2021

Extended reach

99,322
potential audience

Total likes

960

Video views

25,059

Mentions per month

Mar 2021 – Sep 2025

Where it's discussed

  • X / Twitter28 posts
  • News3 articles
  • Facebook2 posts
  • YouTube1 videos

AI synopsis

What people are saying

Several posts mention the combination of creatine and caffeine, debating whether they oppose or support each other's effects, as seen in phrases like 'some evidence suggests they can oppose each other.' The tone ranges from neutral to contemplative, with users referencing specific study outcomes and suggesting nuanced interpretations, which reflects a moderate level of interest and a recognition of the study's potential importance without overestimating its definitive impact.

AgreementNeither agree nor disagree

The discussions show mixed opinions, with some posts referencing study findings but also mentioning opposing evidence or nuanced views, indicating neither strong agreement nor disagreement overall.

InterestModerate interest

Most posts demonstrate curiosity about the research and its implications, especially around caffeine and creatine during resistance training.

EngagementModerate engagement

Many discussions cite specific elements of the publication, such as the effects on body composition and muscle performance, suggesting moderate to deep engagement.

ImpactNeutral impact

While some posts imply potential practical implications, many focus on clarifying or questioning the findings, indicating a perception of moderate impact rather than groundbreaking influence.

Abstract in brief

  • The study investigated how creatine and caffeine, alone and combined, affect body composition and muscle performance during resistance training in trained young adults.
  • Participants took supplements or a placebo before workouts over 6 weeks, with various measurements like muscle size, strength, and endurance assessed before and after the training.
  • The main finding was that creatine supplementation led to a small increase in knee extensor muscle size, but there were no significant differences between groups in other measures such as strength, endurance, or fat mass.]

Top posts

Most liked on X and Bluesky
Jozo Grgic
@Jozo_Grgic · X

Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Rating of Perceived Exertion and Fatigue in Trained Young Adults https://t.co/T8KZjpJBCv

Apr 13, 2021 · 43 likes · 16 shares · 5,477 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

Effects of creatine, with and without caffeine, during resistance training #creatine #caffeine @ScottForbes14 https://t.co/TFUTefwrCN

Mar 24, 2021 · 18 likes · 5 shares · 6,729 followers View post →
Bader alshatti Ms
@alshatti_fit · X

هل يمكنك أخذ الكافيين والكرياتين في نفس الوقت؟ قد لا تكون فعالة. كان هناك تأثير سلبي للكرياتين والكافيين على سماكة العضلات مع نمو أكبر في مجموعة الكرياتين فقط التوصية: خذ الكافين قبل التمرين والكرياتين بعد التمرين في وجبة تحفز الأنسولين. https://t.co/q30KHplB0c

Apr 14, 2021 · 7 likes · 1 share · 9,846 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

@DrMyohead @dnewmire @SarahDeemerPhD @DrCreatine Yes, dietary protein critical (> 1.2 g/kg/day). Creatine can add some additional benefits. There is ‘some’ evidence to suggest that caffeine and creatine can oppose each other https://t.co/qcUlGasLaa https://t.co/4hEujRUfuL https://t.co/gGTIMHgqs2

Oct 21, 2023 · 4 likes · 6,729 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

@SteAssent @coffeeaddict50 https://t.co/4hEujRUfuL

Nov 23, 2022 · 2 likes · 6,729 followers View post →
john morley
@drjohnmorley · X

Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Rating of Perceived Exertion and Fatigue in Trained Young Adults https://t.co/yrl751jyye

Apr 13, 2021 · 1 like · 8,304 followers View post →

All mentions

Take_irakusa
@Take_irakusa · X

@foundmyfitness Yes, you're quite right. Since the differences seem minimal, I think combining creatine and coffee could be a good option for those who want to restore brain function to baseline and use their morning time efficiently https://t.co/XzaIgDsKU4

Sep 19, 2025 · 1,628 followers View post →
William Lagakos
@caloriesproper2 · X

https://t.co/IeqXX4GBBb https://t.co/sLd1r8FyP1

Aug 18, 2025 · 1 like · 3,036 followers View post →
Deborah Gordon, M.D.
@DrDeborahMD · X

@DavidPuder Great info, thank you. I was coached by a Darren Gandow inspired proposal to separate them, couple different rationales--but more nuanced than I had understood. https://t.co/LdRJosNKHI

Jul 30, 2025 · 3,768 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

@DrMyohead @dnewmire @SarahDeemerPhD @DrCreatine Yes, dietary protein critical (> 1.2 g/kg/day). Creatine can add some additional benefits. There is ‘some’ evidence to suggest that caffeine and creatine can oppose each other https://t.co/qcUlGasLaa https://t.co/4hEujRUfuL https://t.co/gGTIMHgqs2

Oct 21, 2023 · 4 likes · 6,729 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

@SteAssent @coffeeaddict50 https://t.co/4hEujRUfuL

Nov 23, 2022 · 2 likes · 6,729 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

@hubermanlab @IHateDannyD Potentially https://t.co/4hEujSbiwL

Aug 24, 2021 · 6,729 followers View post →
Amnh
@Amoon1963 · X

RT @Microscope_B: هل يمكنك أخذ الكافيين والكرياتين في نفس الوقت؟ قد لا تكون فعالة. كان هناك تأثير سلبي للكرياتين والكافيين على سماكة العض…

Apr 19, 2021 · 1 share · 128 followers View post →
Bader alshatti Ms
@alshatti_fit · X

هل يمكنك أخذ الكافيين والكرياتين في نفس الوقت؟ قد لا تكون فعالة. كان هناك تأثير سلبي للكرياتين والكافيين على سماكة العضلات مع نمو أكبر في مجموعة الكرياتين فقط التوصية: خذ الكافين قبل التمرين والكرياتين بعد التمرين في وجبة تحفز الأنسولين. https://t.co/q30KHplB0c

Apr 14, 2021 · 7 likes · 1 share · 9,846 followers View post →
Phoenix Training
@TrainingPhoenix · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 14, 2021 · 16 shares · 134 followers View post →
YURI PAUCAR
@ypaucar · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 1,207 followers View post →
Juhana Harju
@JuhanaHarju · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 1,691 followers View post →
Joaquín San José
@jsanjosea · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 408 followers View post →
Argón
@metilargon · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 352 followers View post →
john morley
@drjohnmorley · X

Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Rating of Perceived Exertion and Fatigue in Trained Young Adults https://t.co/yrl751jyye

Apr 13, 2021 · 1 like · 8,304 followers View post →
fenuso
@fenuso1 · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 124 followers View post →
Kalle Kolari
@Kalle_kolari_ · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 59 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 6,729 followers View post →
Claudio Chinaglia
@claudiochinagli · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 119 followers View post →
Septim
@Septim007 · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 18 followers View post →
Guilherme Pussieldi, PhD
@GPussieldi · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 260 followers View post →
Konstantinos Prokopidis
@KostasProko · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 1,491 followers View post →
Ema.pf
@BlackStrongOk · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 54 followers View post →
Virginia Santesteban
@virginiasanmor3 · X

RT @Jozo_Grgic: Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Ratin…

Apr 13, 2021 · 16 shares · 453 followers View post →
Jozo Grgic
@Jozo_Grgic · X

Effects of Creatine and Caffeine Supplementation During Resistance Training on Body Composition, Strength, Endurance, Rating of Perceived Exertion and Fatigue in Trained Young Adults https://t.co/T8KZjpJBCv

Apr 13, 2021 · 43 likes · 16 shares · 5,477 followers View post →
fenuso
@fenuso1 · X

RT @darrencandow: Effects of creatine, with and without caffeine, during resistance training #creatine #caffeine @ScottForbes14 https://t…

Mar 25, 2021 · 5 shares · 124 followers View post →
The Powermania
@PowermaniaT · X

RT @darrencandow: Effects of creatine, with and without caffeine, during resistance training #creatine #caffeine @ScottForbes14 https://t…

Mar 24, 2021 · 5 shares · 48 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @darrencandow: Effects of creatine, with and without caffeine, during resistance training #creatine #caffeine @ScottForbes14 https://t…

Mar 24, 2021 · 5 shares · 1,365 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

Effects of creatine, with and without caffeine, during resistance training #creatine #caffeine @ScottForbes14 https://t.co/TFUTefwrCN

Mar 24, 2021 · 18 likes · 5 shares · 6,729 followers View post →