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The discussions reflect a cautious but intrigued tone, with mentions of research articles, chemical structures, and potential societal implications, such as the comparison of nitazenes to fentanyl and comments on drug potency and legal challenges. Words like 'comprehensive review' and references to specific scientific papers convey a serious attitude, while some social remarks reveal skepticism about drug trends, demonstrating a nuanced overall perception of the publication’s importance.
Posts show mixed reactions, with some acknowledging the depth of the review but also some dismissive or skeptical comments about the drugs' relevance or use.
There is a generally moderate interest, especially among those involved in research, drug safety, or forensic analysis, but some posts are more superficial or off-topic.
The discussion includes references to detailed chemical studies and regulatory impacts, indicating thoughtful engagement, but some comments are brief or informal.
The publication is seen as impactful due to its relevance to public health and drug policy, with mentions of drug potency and legal issues highlighting its significance.
Once the Fentanyl doesn’t work here is where everyone is going to https://t.co/xVgQvVcTbh
Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with opioid-like properties, and the recent emergence & subsequent health impact of some of these opioid NPS has just been published. https://t.co/oLs6YHWo7S
Flunitazene: the next 'nitazene' to appear in cases. Activity data shown below (panel D, pink) - for more background on activity, check out research paper by @Marthevdp et al. (https://t.co/w634uW5ekG) & #darkclassics review by @IUjvary et al. (https://t.co/MVoe01jthP)(2d online) https://t.co/EydNliqpSb https://t.co/PVk5osKBW0
@RyanMarino https://t.co/jjwgHkKm3M
@judithyates1 @BinghamInfo @WeDinos @drugsdotie See https://t.co/w634uWmPJg for our work on these -and other- 'nitazenes', and also don't forget to check out the 'DARK Classics' review by @IUjvary on etonitazene and related benzimidazoles. https://t.co/MVoe01B4Gp
#Nitazenes being mentioned by Mike as 'attractive to dealers', owing to high potency vs relatively cheap synthesis. Reviewed by @IUjvary (https://t.co/9eoEz2G0Wr), referring to work by @Marthevdp (https://t.co/RUpQ7kBhV4). https://t.co/y3oXYxBM94
This video explores Nitazenes, potent opioid compounds with a history rooted in benzimidazoles like etonitazene, developed in the 1950s. It covers their discovery, reemergence in illegal markets, and the challenges they…
This video explores the chemistry and history of benzimidazoles like etonitazene, potent painkillers developed in the 1950s. It discusses their opioid effects, misuse potential, and the challenges they pose for…
@mariazuppello @debe Ho trovato anche questo: "DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles," pubblicato su ACS Chemical Neuroscience nel 2021 (Vol. 12, N. 7, pagine 1072–1092). Dovrebbe essere un revisione approfondita sul tema dei nitazeni. Non sono in
Key reviews cited in WHO"s Critical Review Reports: DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles. doi: 10.1002/dta.3519 Hexahyrocannabinol and& closely related semi-synthetic cannabinoids: A comprehensive review. doi: 10.1021/acschemneuro.1c00037 https://t.co/ASMITfHol1
@cacaph @jonassmarques Uns artigos, só titulo "Synthesis, Chemical Characterization, and μ-Opioid Receptor Activity Assessment of the Emerging Group of “Nitazene” 2-Benzylbenzimidazole Synthetic Opioids "DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles"
Itt appears that the important carbamoyl substituent on the benzylic C-atom is missing. See the potent Compound 54 (R1 = CONH2) in our 2021-review. DOI: 10.1021/acschemneuro.1c00037 https://t.co/jTxNfMtuUc https://t.co/eOQOr9gIGv
Nitazenes: The Next Fentanyl? https://t.co/dHuN2Is3z9 via @YouTube
Nitazenes: The Next Fentanyl? https://t.co/MGpaujE3ou via @YouTube
@javioffa30 I think you should give Tranq a try I hear it’s better for you. Or any of the zine drugs they are stronger than fent https://t.co/EBJl7K0wNy
Nitazenes: The Next Fentanyl? https://t.co/8CanUP7Bb0 via @YouTube
RT @Professor_615: Once the Fentanyl doesn’t work here is where everyone is going to https://t.co/xVgQvVcTbh
https://t.co/M54VMFo1Mj
https://t.co/M54VMFozBR
RT @Professor_615: Once the Fentanyl doesn’t work here is where everyone is going to https://t.co/xVgQvVcTbh
RT @Professor_615: Once the Fentanyl doesn’t work here is where everyone is going to https://t.co/xVgQvVcTbh
RT @Professor_615: Once the Fentanyl doesn’t work here is where everyone is going to https://t.co/xVgQvVcTbh
RT @Professor_615: Once the Fentanyl doesn’t work here is where everyone is going to https://t.co/xVgQvVcTbh
RT @Professor_615: Once the Fentanyl doesn’t work here is where everyone is going to https://t.co/xVgQvVcTbh
RT @Professor_615: Once the Fentanyl doesn’t work here is where everyone is going to https://t.co/xVgQvVcTbh
RT @Professor_615: Once the Fentanyl doesn’t work here is where everyone is going to https://t.co/xVgQvVcTbh
Once the Fentanyl doesn’t work here is where everyone is going to https://t.co/xVgQvVcTbh
Nitazenes https://t.co/CMdDNxY668
Nitazenes: The Next Fentanyl? https://t.co/XUouOZbvtW via @YouTube #NextFentanyl
https://t.co/TcJoseAAeI
@oohheyk8 @clairezagorski From a recent review: https://t.co/Oj7URAXAxc I believe that the introduction of fentanyl invented around the same time by Paul Janssen played also a role in the shelving by CIBA of such 2-benzylbenzimidazoles. https://t.co/pK4nwQ3z2Z
The many faces of benzimidazole-containing bioactive substances. A reminder. https://t.co/Oj7URAXAxc https://t.co/1b4uATrrho https://t.co/V7w3Dz3MdE
RT @christophestove: @judithyates1 @BinghamInfo @WeDinos @drugsdotie See https://t.co/w634uWmPJg for our work on these -and other- 'nitazen…
@judithyates1 @BinghamInfo @WeDinos @drugsdotie See https://t.co/w634uWmPJg for our work on these -and other- 'nitazenes', and also don't forget to check out the 'DARK Classics' review by @IUjvary on etonitazene and related benzimidazoles. https://t.co/MVoe01B4Gp
people naming new drugs like they woke up and found their bank accounts had been cleared out. https://t.co/kHMLeKrIiV
@RyanMarino https://t.co/jjwgHkKm3M
#Nitazenes being mentioned by Mike as 'attractive to dealers', owing to high potency vs relatively cheap synthesis. Reviewed by @IUjvary (https://t.co/9eoEz2G0Wr), referring to work by @Marthevdp (https://t.co/RUpQ7kBhV4). https://t.co/y3oXYxBM94
RT @IUjvary: Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with…
RT @IUjvary: Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with…
RT @IUjvary: Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with…
RT @IUjvary: Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with…
RT @IUjvary: Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with…
RT @IUjvary: Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with…
RT @IUjvary: Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with…
RT @IUjvary: Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with…
RT @IUjvary: Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with…
Our comprehensive overview on 6 decades of med chem research on 2-benzylbenzimidazole derivatives & their close analogues with opioid-like properties, and the recent emergence & subsequent health impact of some of these opioid NPS has just been published. https://t.co/oLs6YHWo7S
RT @Cayman_Forensic: DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles - A nice review on Nitazenes by @IUjvar…
DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles - A nice review on Nitazenes by @IUjvary and team: https://t.co/UYNSc7eoh7 https://t.co/H6LGmh92FS
DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles https://t.co/KCerneSif5
Flunitazene: the next 'nitazene' to appear in cases. Activity data shown below (panel D, pink) - for more background on activity, check out research paper by @Marthevdp et al. (https://t.co/w634uW5ekG) & #darkclassics review by @IUjvary et al. (https://t.co/MVoe01jthP)(2d online) https://t.co/EydNliqpSb https://t.co/PVk5osKBW0
In the mouse tail flick assay of antinociception, flunitazene sc was found to be as potent as morphine nicely reflecting in vitro data. https://t.co/AKaWxTOAcP https://t.co/mfhCIbXUUg https://t.co/an27E104cZ
RT @IUjvary: The paper was published promptly (within 10 hours) with required changes! Incredible fast & quality work of the editorial offi…
The paper was published promptly (within 10 hours) with required changes! Incredible fast & quality work of the editorial office @ACSChemNeurosci https://t.co/Oj7URAXAxc
Online at @ACSChemNeurosci, just a few hours after the proofs were returned: "DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles": #RecommendReading (take your time
10.1021/acschemneuro.1c00037. Epub 2021 Mar 24. PMID: 33760580. United Nations Office on Drugs and Crime (2020). 'UNODC EWA: Brorphine, a newly emerging ...
... 10.1021/acschemneuro.1c00037 · Like · Reply · 2 Reactions 3 Reactions. See more comments. To view or add a comment, sign in. Explore content ...
... 10.1021/acschemneuro.1c00037 4. https://drugchecking.community/drug-information/etonitazene/. Дата публикации информации / Оператор: YL 28.03 ...
Overview of Affinities of Benzimidazole Opioids · https://sci-hub.hkvisa.net/10.1021/acschemneuro.1c00037. This Study is for Etonitazepipne:.
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