"N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab, @DavideCorti6, and Matteo Samuele Pizzuto now in @CellCellPress https://t.co/dRSFI7z4OQ @Vir_Biotech @UW https://t.co/zAmOAcizux
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.
Mentions
Extended reach
Total likes
Video views
Mentions per month
Jan 2021 – Dec 2021Where it's discussed
-
X / Twitter64 posts
-
News63 articles
-
Blogs5 articles
-
YouTube2 videos
-
Facebook2 posts
-
Reddit2 posts
AI synopsis
What people are saying
The discussions highlight important findings from the publication, such as the identification of neutralizing antibodies against the N-terminal domain of the SARS-CoV-2 spike protein. Phrases like 'potent inactivators' and 'critical area for neutralization' are prevalent, showcasing an optimistic tone that underscores the research's potential for vaccine and treatment advancements.
The majority of discussions show strong support for the findings of the publication, indicating a consensus on the importance of the research.
The posts reflect a high level of curiosity about the implications of the study, especially its relevance to vaccine development.
While many users express interest, some posts are more surface-level, focusing on sharing links rather than providing in-depth analyses or discussions.
Overall, individuals perceive the research as having significant implications for understanding and combating SARS-CoV-2.
Abstract in brief
- The study investigates human monoclonal antibodies (mAbs) that target the N-terminal domain (NTD) of the SARS-CoV-2 spike protein, highlighting their ability to neutralize the virus effectively.
- Researchers created an antigenic map for the NTD and identified a critical area, termed "site i," recognized by most neutralizing mAbs, which can inhibit viral fusion and activate immune responses.
- The presence of mutations in the NTD supersite among various SARS-CoV-2 variants indicates the ongoing evolution of the virus and underscores the need for NTD-specific mAbs in developing effective vaccines and treatments.
Top posts
Most liked on X and BlueskyNew Article now online: N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/L9gG6Isub1
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/VMEnn13Wi1 #biorxiv_immuno
#bioRxiv N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/YEbSiqqK1z 41 human monoclonal Abs (mAbs) from memory B cells recognize the SARS-CoV-2 S N-terminal domain (NTD); a subset of them neutralize SARS-CoV-2 ultrapotently. https://t.co/mx5ZCwvRnx
N-terminal domain antigenic mapping reveals a site of vulnerability for #SARSCOV2 - neutralization more targets in spike more that just about the receptor binding domain https://t.co/qqdjj8ndBR
Proud to feature the work of @veeslerlab and colleagues at @UW. His paper in Cell features the use of Promega’s ADCC and ADCP Reporter Bioassays to define the role of Fc-mediated effector functions in mAb-mediated anti-viral responses: https://t.co/qTDpjq6kAz https://t.co/a4ZIHlD4ez
All mentions
Understanding the Mortality Drivers of the Delta Variant
This video explores the delta coronavirus variant, detailing its mutations and the reasons behind its classification as a variant of concern. Research shows that while a single vaccine dose has lower efficacy against…
Understanding NTD Antibodies in SARS-CoV-2 Research
This week’s scientific report delves into the effectiveness of human monoclonal antibodies targeting the N-terminal domain of SARS-CoV-2. We explore a critical vulnerability site and discuss the implications for vaccine…
Proud to feature the work of @veeslerlab and colleagues at @UW. His paper in Cell features the use of Promega’s ADCC and ADCP Reporter Bioassays to define the role of Fc-mediated effector functions in mAb-mediated anti-viral responses: https://t.co/qTDpjq6kAz https://t.co/a4ZIHlD4ez
N-terminal domain antigenic mapping reveals a site of vulnerability for #SARSCoV2 https://t.co/dLB3WFyjZK
Monoclonal antibodies derived from memory B cells recognize #SARSCoV2 S N-terminal domain (NTD), a subset of them neutralize the virus ultrapotently: no fusion with the cell❗Not in actual #vaccines targeting ONLY ACE2 receptor binding domain RBD #COVID19 https://t.co/HrRSZ5L1YX
Reportes Cientificos Semanales Mayo Semana 2, 2021 https://t.co/fdxdwmXj2v via @YouTube
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/JBYwnowseJ
新型コロナウイルスのスパイクタンパクのN末端ドメインのエピトープマッピング Cell. 2021 Mar 16;S0092-8674(21)00356-1. doi: 10.1016/j.cell.2021.03.028. https://t.co/QrgzKs698U
RT @dogface2016: 2021年4月21日: Pythonで送る最新のCell Press N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2|htt…
2021年4月21日: Pythonで送る最新のCell Press N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2|https://t.co/s7d2Ks4zuq
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
"N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab, @DavideCorti6, and Matteo Samuele Pizzuto now in @CellCellPress https://t.co/dRSFI7z4OQ @Vir_Biotech @UW https://t.co/zAmOAcizux
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CellPressNews: "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" - Read the article by @veeslerlab,…
RT @CovidReference: https://t.co/I2Njxh17Ed The authors describe 41 mAbs derived which recognize the SARS-CoV-2 S N-terminal domain (NTD).…
https://t.co/I2Njxh17Ed The authors describe 41 mAbs derived which recognize the SARS-CoV-2 S N-terminal domain (NTD). A subset of the mAbs neutralize SARS-CoV-2 ultrapotently. Hence the importance of NTD-specific neutralizing mAbs for protective immunity and vaccine design. https://t.co/NYAkEYQzgo
(resolved link: https://t.co/gXliQ4iBq8 "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2") https://t.co/dofeQCRHqv
RT @DelthiaRicks: A lesser-studied region on SARSCoV2 is recognized by by antibodies. The antibodies attach to the N-terminal viral domain…
RT @DelthiaRicks: A lesser-studied region on SARSCoV2 is recognized by by antibodies. The antibodies attach to the N-terminal viral domain…
RT @DelthiaRicks: A lesser-studied region on SARSCoV2 is recognized by by antibodies. The antibodies attach to the N-terminal viral domain…
RT @DelthiaRicks: A lesser-studied region on SARSCoV2 is recognized by by antibodies. The antibodies attach to the N-terminal viral domain…
RT @DelthiaRicks: A lesser-studied region on SARSCoV2 is recognized by by antibodies. The antibodies attach to the N-terminal viral domain…
RT @DelthiaRicks: A lesser-studied region on SARSCoV2 is recognized by by antibodies. The antibodies attach to the N-terminal viral domain…
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/Lcyq2EBTfM
N-terminal domain antigenic mapping reveals a site of vulnerability for #SARSCoV2: Cell https://t.co/qMqJ3Nhg4u
RT @NSERC_CRSNG:
RT @CellCellPress: New Article now online: N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/…
RT @CellCellPress: New Article now online: N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/…
RT @CellCellPress: New Article now online: N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/…
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/HuCSHpLvU8
RT @CellCellPress: New Article now online: N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/…
RT @CellCellPress: New Article now online: N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/…
New Article now online: N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/L9gG6Isub1
RT @MichaelBuratovi: Antibodies against the spike N-terminus are potent inactivators for SARS-CoV-2. See N-terminal domain antigenic mappin…
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 | bioRxiv https://t.co/fVRq60QzWN
Antibodies against the spike N-terminus are potent inactivators for SARS-CoV-2. See N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/VJUPThwV4d
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 | bioRxiv https://t.co/iBqxcNryJh
RT @emulenews: #bioRxiv N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/YEbSiqqK1z 41 human…
RT @emulenews: #bioRxiv N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/YEbSiqqK1z 41 human…
#bioRxiv N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/YEbSiqqK1z 41 human monoclonal Abs (mAbs) from memory B cells recognize the SARS-CoV-2 S N-terminal domain (NTD); a subset of them neutralize SARS-CoV-2 ultrapotently. https://t.co/mx5ZCwvRnx
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 [ Preprint - not peer reviewed ] https://t.co/pAQ46CK61r
RT @SouthAfricanASP: N-terminal domain antigenic mapping reveals a site of vulnerability for #SARSCOV2 - neutralization more targets in spi…
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/WJocqR1n4g #immunobot https://t.co/UcSp75lY1T
RT @SouthAfricanASP: N-terminal domain antigenic mapping reveals a site of vulnerability for #SARSCOV2 - neutralization more targets in spi…
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/wWADHY2ndZ
N-terminal domain antigenic mapping reveals a site of vulnerability for #SARSCOV2 - neutralization more targets in spike more that just about the receptor binding domain https://t.co/qqdjj8ndBR
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/nJvLEwlYy2 #glycotime
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/M1Ud97yONY
RT @biorxiv_immuno: N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/VMEnn13Wi1 #biorxiv_im…
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2: SARS-CoV-2 entry into host cells is orchestrated by the spike (S) glycoprotein that contains an immunodominant receptor-binding domain (RBD) targeted by the largest… https://t.co/Eay8SHQa9p
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/VMEnn13Wi1 #biorxiv_immuno
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2 https://t.co/t7qFGEFPum #bioRxiv
CP
C
BI
FV
MM
PC
KR
ML
PM
テ
GP
ぼ
TW
NB
E
RB
CM
AB
A
SF
GN
Dا
MR
ST
ES
MJ
AJ
UB
TL
RC
CR
M
TR
C
TJ
KS
AB
SJ
A
C
GM
BP
YP
OA
UR
BW
M
MB
DM
A
RI
LA
P
DC
M
P
G
BI
NU
M
B