Respir Res April 2021 PMID 33823870

Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions.

Atish Gheware, Dhwani Dholakia, Sadasivam Kannan, Lipsa Panda, Ritu Rani, Bijay Ranjan Pattnaik, Vaibhav Jain, Yash Parekh, M Ghalib Enayathullah, Kiran Kumar Bokara, Venkatesan Subramanian, Mitali Mukerji, Anurag Agrawal, Bhavana Prasher

Mentions

40
Peak: 13 in Apr 2021
across 2 sources since Apr 2021

Extended reach

515,920
potential audience

Total likes

2,785

Video views

274,728

Mentions per month

Apr 2021 – Dec 2023

Where it's discussed

  • X / Twitter36 posts
  • YouTube4 videos

AI synopsis

What people are saying

This collection of discussions demonstrates a high level of agreement about the importance and potential of the research, with many posts exploring its implications for COVID-19 treatment and Ayurgenomics. The tone is scientifically curious and optimistic, with examples such as mentions of the extract's anti-inflammatory properties and calls for expert feedback, reflecting both interest and engagement among participants interested in medical advancements and traditional medicine integration.

AgreementStrong agreement

Many discussions affirm the significance of the research, highlighting its potential therapeutic value and approving the findings about Adhatoda Vasica’s effects.

InterestHigh interest

There is high curiosity expressed about the implications for COVID-19 treatment and interest in Ayurgenomics, showing active engagement with the research relevance.

EngagementHigh engagement

Posts involve analysis of research data, references to studies, and calls for feedback, indicating deep involvement rather than superficial attention.

ImpactModerate impact

The discussions suggest the research could have meaningful influence on COVID-19 management strategies and Ayurvedic practices, though some see it as preliminary.

Abstract in brief

  • Adhatoda Vasica (AV) extract has shown anti-inflammatory and anti-hypoxic effects in mouse models of lung injury, sepsis, and blood clotting, potentially reducing lung inflammation and improving survival.
  • The study found that AV treatment decreases genes associated with hypoxia, inflammation, and blood vessel growth, while boosting immune response genes, and it also lowers SARS-CoV-2 viral load in cell experiments.
  • These findings suggest that AV could be repurposed as a therapeutic option for COVID-19-related lung damage, hypoxia, and hyperinflammation.]

Top posts

Most liked on X and Bluesky
CSIR-CCMB
@ccmb_csir · X

Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication in the current #COVID19 crisis? A recent study in collaboration between @IGIBSocial, us and @clriindia looks into it. @CSIR_IND https://t.co/ri761wsZ8F

Apr 9, 2021 · 27 likes · 9 shares · 29,340 followers View post →
Carlos Wambier, MD PhD
@WambierMD · X

@ZimermanRicardo Ambroxol que é um metabólito da Bromhexina, que é derivada do princípio ativo da planta Justicia adhotada, também conhecida como Adhatoda Vasica. Como nos meus estudos do Óleo de Croton, a ação do extrato completo é geralmente superior que uma molécula. https://t.co/bGgBSXUtDH

Aug 9, 2021 · 2 likes · 3,447 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@VPolshettiwar @vraman16 Prof. I would love to hear your feedback on my lecture on Ayurgenomics insights for COVID19 based on latest research evidence from IGIB and scientists from dept. of @moayush . Pls watch when u get time. https://t.co/T4jULWaIWd

Jun 22, 2021 · 2 likes · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@bachalakarthiek @ParuchuriMallik In the below video, I have taken more complete data from PHE studies: https://t.co/WYHRXEddgs

Jun 22, 2021 · 1 like · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

My lecture on Ayurgenomics (Genetic basis for Prakriti in Ayurveda). I first heard this word from Prof. @ARanganathan72 in his excellent article in 2014 @madhukishwar. Surprising that not even 3-4 Utube videos are available on this topic to date.. https://t.co/T4jULWaIWd

May 29, 2021 · 1 like · 2 shares · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@RGVzoomin My analysis on @ParuchuriMallik observations on COVID19 Vaccines vs. Variants based on latest research evidence from PHE, PHS & CMC Vellore Studies: Part 2 https://t.co/jamS0f4qm8

Jun 20, 2021 · 1 like · 300 followers View post →

All mentions

luxeradiancebeauty
@pbalachandran30 · X

@MoHFW_INDIA @mansukhmandviya @spsinghbaghelpr @DrBharatippawar @PMOIndia @PIB_India @DDNewslive @airnewsalerts @mygovindia Malabar Nut or Adhatoda Vasica https://t.co/V8D1PnDbXf

Dec 20, 2023 · 53 followers View post →
luxeradiancebeauty
@pbalachandran30 · X

@RCHMelbourne @transcend_aust https://t.co/V8D1PnDbXf

Feb 5, 2023 · 53 followers View post →
anxeru
@anxeru · X

Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions https://t.co/qlrEAxiGFZ https://t.co/7piM8fIuuI

Dec 22, 2022 · 33 followers View post →
Carlos Wambier, MD PhD
@WambierMD · X

@ZimermanRicardo Ambroxol que é um metabólito da Bromhexina, que é derivada do princípio ativo da planta Justicia adhotada, também conhecida como Adhatoda Vasica. Como nos meus estudos do Óleo de Croton, a ação do extrato completo é geralmente superior que uma molécula. https://t.co/bGgBSXUtDH

Aug 9, 2021 · 2 likes · 3,447 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@dasgobardhan @ARanganathan72 I would like to know your views on some latest research articles on Ayurgenomics that provide insights on variation in immune responses in COVID based on Prakriti. outlined in my video with references. https://t.co/T4jULWaIWd

Jul 1, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@DrSunny18677348 @Bholasankaraa @ParuchuriMallik @RGVzoomin @drmssm @KTRTRS Sir, pls watch this video in which I explained I completely disagree with him on vaccines. I didn't pass any derogatory comments on doctors. Pls take that statement back. https://t.co/jamS0f4qm8

Jun 28, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@VPolshettiwar @vraman16 Prof. I would love to hear your feedback on my lecture on Ayurgenomics insights for COVID19 based on latest research evidence from IGIB and scientists from dept. of @moayush . Pls watch when u get time. https://t.co/T4jULWaIWd

Jun 22, 2021 · 2 likes · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@vraman16 @AtharvaForum Very enlightening lecture...Sir, I made a video lecture on Ayurgenomics insights for COVID19. Pls watch when u have time & provide feedback. https://t.co/T4jULWaIWd

Jun 22, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@bachalakarthiek @ParuchuriMallik In the below video, I have taken more complete data from PHE studies: https://t.co/WYHRXEddgs

Jun 22, 2021 · 1 like · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@Sahana72007706 Can you please email pdf to baswanth.oruganti@gmail.com as I don't have access? I would very much appreciate if you can also provide feedback on my below video on Pharmaco/Ayur-genomics COVID insights (based on Prof. Mitali Mukherjee research) https://t.co/T4jULWaIWd

Jun 20, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@RGVzoomin My analysis on @ParuchuriMallik observations on COVID19 Vaccines vs. Variants based on latest research evidence from PHE, PHS & CMC Vellore Studies: Part 2 https://t.co/jamS0f4qm8

Jun 20, 2021 · 1 like · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@drmssm Sir, I made a detailed video on how Vaccines protect us from 3rd wave outlining research evidence on Vaccine effectiveness from PHE, PHS & CMC Vellore studies, and also incorporating some of your views. Do watch: https://t.co/jamS0f4qm8

Jun 20, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@LAKSHMIALAPATI3 @drmssm @YouTube @drmssm Sir, I made a detailed video on how Vaccines protect us from 3rd wave outlining research evidence on Vaccine effectiveness from PHE, PHS & CMC Vellore studies, and also incorporating some of your views. Do watch: https://t.co/jamS0f4qm8

Jun 20, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

My analysis on @ParuchuriMallik observations on COVID19 Vaccines vs. Variants based on latest research evidence from PHE, PHS & CMC Vellore Studies: https://t.co/jamS0f4qm8

Jun 19, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@Nishita_Chy @Anjna116 @hathyogi31 @VaibhavOfDharma @Satyamev1310 @sri9011 @Sayani_Pandit Madam, I have recently done a video lecture on the correlation between gene expression and Ayurvedic concept of Prakriti summarizing recent research findings in Ayurgenomics. Pls watch and provide feedback.. https://t.co/T4jULWaIWd

Jun 6, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@Nishita_Chy Madam, I have recently done a video lecture on the correlation between gene expression and Ayurvedic concept of Prakriti summarizing recent research findings in Ayurgenomics. Pls watch and provide feedback.. https://t.co/T4jULWaIWd

Jun 6, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@yogrishiramdev @News18India @CNBCTV18Live @CNBC_Awaaz @News18UP @News18Rajasthan @News18MP @News18Bihar @News18Jharkhand @News18Odia @News18Bengali My lecture on Ayurgenomics in COVID Management and genetic basis for Ayurveda...@PypAyurved @Ach_Balkrishna @MoHFW_INDIA @moayush @drharshvardhan Thanks a lot @mukerjim https://t.co/T4jULWaIWd

May 30, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@youngndharmic My lecture on how Ayurveda can provide insights into managing COVID using research evidence on Ayurgenomics from last 15 years... https://t.co/T4jULWaIWd

May 30, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@fgautier26 My lecture on genetic basis for Ayurveda summarizing Ayurgenomics research evidence over last 15 years.. https://t.co/T4jULWaIWd

May 30, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@dravirmani @TheJaggi My lecture on Genetic basis for Ayurveda summarizing Ayurgenomics research over last 15 years... https://t.co/T4jULWaIWd

May 30, 2021 · 300 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

@madhukishwar My lecture on Genetic basis for Ayurveda based on research evidence..Please watch Madam... https://t.co/T4jULWaIWd

May 30, 2021 · 300 followers View post →
v.bhargav
@vbhargavraj · X

RT @BaswanthQuantum: My lecture on Ayurgenomics (Genetic basis for Prakriti in Ayurveda). I first heard this word from Prof. @ARanganathan7…

May 29, 2021 · 2 shares · 21 followers View post →
Baswanth Oruganti
@BaswanthQuantum · X

My lecture on Ayurgenomics (Genetic basis for Prakriti in Ayurveda). I first heard this word from Prof. @ARanganathan72 in his excellent article in 2014 @madhukishwar. Surprising that not even 3-4 Utube videos are available on this topic to date.. https://t.co/T4jULWaIWd

May 29, 2021 · 1 like · 2 shares · 300 followers View post →
Ulia Khareva
@KUlia333 · X

RT @ccmb_csir: Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication…

Apr 15, 2021 · 9 shares · 94 followers View post →
lipsa panda
@imlipsa · X

RT @ccmb_csir: Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication…

Apr 10, 2021 · 9 shares · 1,126 followers View post →
Dr Bhartendu Vimal ↗️
@bhvml · X

RT @ccmb_csir: Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication…

Apr 9, 2021 · 9 shares · 1,267 followers View post →
Hasan Jawaid Khan
@hjkhan · X

RT @ccmb_csir: Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication…

Apr 9, 2021 · 9 shares · 2,895 followers View post →
anil gupta
@anilgb · X

RT @ccmb_csir: Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication…

Apr 9, 2021 · 9 shares · 13,906 followers View post →
Transcriptomes
@transcriptomes · X

Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: po... https://t.co/vHeFIPKJjT

Apr 9, 2021 · 1,811 followers View post →
CSIR-IGIB
@IGIBSocial · X

RT @ccmb_csir: Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication…

Apr 9, 2021 · 9 shares · 18,290 followers View post →
Science Bagels
@ScienceBagels · X

RT @ccmb_csir: Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication…

Apr 9, 2021 · 9 shares · 405 followers View post →
CSIR-CLRI
@clriindia · X

RT @ccmb_csir: Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication…

Apr 9, 2021 · 9 shares · 3,657 followers View post →
CSIR, India
@CSIR_IND · X

RT @ccmb_csir: Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication…

Apr 9, 2021 · 9 shares · 155,631 followers View post →
CSIR-CCMB
@ccmb_csir · X

Aqueous extract of Adhatoda vasica is known to show anti-inflammatory and anti-hypoxic effects. Can this have an implication in the current #COVID19 crisis? A recent study in collaboration between @IGIBSocial, us and @clriindia looks into it. @CSIR_IND https://t.co/ri761wsZ8F

Apr 9, 2021 · 27 likes · 9 shares · 29,340 followers View post →
Respiratory Medicine Portfolio
@RespiratoryBMC · X

Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions https://t.co/ig9kliwELB

Apr 8, 2021 · 3,390 followers View post →
AdapMolEvol papers
@adapmolevol · X

Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions https://t.co/oucTpo6MxN

Apr 7, 2021 · 185 followers View post →