April 2021 PMID 33888689

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies.

William S Harris, Nathan L Tintle, Fumiaki Imamura, Frank Qian, Andres V Ardisson Korat, Matti Marklund, Luc Djoussé, Julie K Bassett, Pierre-Hugues Carmichael, Yun-Yu Chen, Yoichiro Hirakawa, Leanne K Küpers, Federica Laguzzi, Maria Lankinen, Rachel A Murphy

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Mentions

59
Peak: 34 in Apr 2021
across 5 sources since Apr 2021

Extended reach

693,148
potential audience

Total likes

211

Video views

996

Mentions per month

Apr 2021 – Oct 2025

Where it's discussed

  • X / Twitter40 posts
  • Instagram12 posts
  • News4 articles
  • YouTube2 videos
  • Blogs1 articles

AI synopsis

What people are saying

The group of social discussions consistently highlights the strength of the meta-analysis linking high blood omega-3 levels to lower mortality, with phrases like 'quite astounding' and 'high-quality pooled analysis,' indicating strong agreement and interest. The tone reflects both scientific appreciation and personal emphasis on dietary changes, showing deep engagement and perceived high impact on health practices.

AgreementStrong agreement

Most posts strongly support the findings, emphasizing the significance of omega-3 levels in reducing mortality.

InterestHigh interest

Posts demonstrate high interest, with participants citing comprehensive analyses and advocating for increased awareness.

EngagementHigh engagement

Discussions include references to specific studies, data interpretation, and personal opinions, indicating deep engagement.

ImpactHigh impact

The overwhelming focus on the potential health benefits suggests a belief that this research could influence dietary recommendations and public health policies.

Abstract in brief

  • A comprehensive analysis of 17 cohort studies over 16 years shows that higher blood levels of long-chain omega-3 fatty acids (like EPA and DHA) are linked to a 15-18% reduction in the risk of death from all causes, including heart disease and cancer.
  • The study found no significant link between the plant-based omega-3 (alpha-linolenic acid) and mortality risk, indicating the benefits are specific to marine-derived omega-3s.
  • Overall, the findings support the idea that increasing circulating levels of marine omega-3 fatty acids may help lower the risk of early death.]

Top posts

Most liked on X and Bluesky
Peter Attia
@PeterAttiaMD · X

Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp at higher levels of RBC EPA/DHA are important and target a minimum of 8% in my patients, and ideally north of 10%. https://t.co/UIrKOfCqru

Apr 24, 2021 · 151 likes · 18 shares · 515,692 followers View post →
htw
@heniek_htw · X

PUFAs & Longevity ➡️ This meta-analysis including over 40,000 participants from 17 cohorts across 10 countries found that high circulating levels of LC n-3 PUFAs, but not ALA, were associated with about a 15–18% lower risk of total mortality.

Apr 23, 2021 · 17 likes · 6 shares · 11,344 followers View post →
Pon|食と健康
@PonNutr · X

Nat commからオメガ3系脂肪酸に関するメタアナが出ていて、面白いです! ✅EPA、DPA、DHAなど魚介由来は全ての死亡、CVD、がん、その他の原因の死亡、全てに予防的 ✅αリノレン酸は効果なし リノレン酸は体に良いけど、魚由来

Apr 30, 2021 · 8 likes · 1 share · 2,792 followers View post →
ساره RDN
@sarahrdn8 · X

كما أنه يرتبط بطول أو قصر الحياه تشير دراسة حديثة أن الأشخاص الذين لديهم مستويات عاليه من أوميغا-3 DHA+EPA أقل عرضة للوفاة المبكر من جميع الأسباب مقارنة بالآخرين https://t.co/qHs26XwxZt

Oct 6, 2021 · 6 likes · 1 share · 10,148 followers View post →
Nick Krontiris
@nick_krontiris · X

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies (open access) https://t.co/vHwlcm4hzx #nutrition #diet #PUFAs #Omega3 #CVD #cancer #longevity

Apr 23, 2021 · 4 likes · 3 shares · 19,484 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies https://t.co/8K7fYv7tTs

Apr 10, 2022 · 4 likes · 1 share · 9,747 followers View post →

All mentions

Kyle Kettler MD
@KyleKettlerMD · X

@reallytanman See this meta analysis on blood omega 3 levels and all cause mortality https://t.co/5KDGxEi43G

Mar 1, 2023 · 122 followers View post →
Anand Samuel
@Anand_A_Samuel · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Jan 23, 2023 · 18 shares · 123 followers View post →
Jeffery Heileson
@jheilesonRD · X

@ScepticalDoctor @skepcard It is interesting, esp in this population, but may be the exception. Higher omega-3 blood levels from other cohort's report significantly lower ACM, CVDM, and cancer mortality (EPA/DPA only). Always more work to be done! https://t.co/HLx2SGLtfC

Nov 21, 2022 · 836 followers View post →
Tomo Takada
@toroeater · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 23, 2022 · 18 shares · 17,946 followers View post →
Agnes Ayton
@AgnesAyton · X

RT @mike_lustgarten: Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies https://t.co/8K7fYv7t…

Apr 10, 2022 · 1 share · 7,422 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies https://t.co/8K7fYv7tTs

Apr 10, 2022 · 4 likes · 1 share · 9,747 followers View post →
Jason Polreis
@JPolreis · X

And omega-3 status with measuring the Omega-3 Index. https://t.co/Z5BXjdIRbD https://t.co/OrCHnmKQhA

Dec 8, 2021 · 1 like · 48 followers View post →
d b
@dannyrbarrera · X

@rumapumpum @DrFuhrman https://t.co/DoxWtZatj9

Nov 1, 2021 · 21 followers View post →
d b
@dannyrbarrera · X

@DrFuhrman https://t.co/DoxWtZatj9

Nov 1, 2021 · 21 followers View post →
ساره RDN
@sarahrdn8 · X

كما أنه يرتبط بطول أو قصر الحياه تشير دراسة حديثة أن الأشخاص الذين لديهم مستويات عاليه من أوميغا-3 DHA+EPA أقل عرضة للوفاة المبكر من جميع الأسباب مقارنة بالآخرين https://t.co/qHs26XwxZt

Oct 6, 2021 · 6 likes · 1 share · 10,148 followers View post →
ENDALA klinika zdraví
@endalaclinic · X

RT @heniek_htw: PUFAs & Longevity ➡️ This meta-analysis including over 40,000 participants from 17 cohorts across 10 countries found that…

May 31, 2021 · 6 shares · 254 followers View post →
nobnak
@nobuyuki_nakata · X

RT @Pon_yurublog: Nat commからオメガ3系脂肪酸に関するメタアナが出ていて、面白いです! ✅EPA、DPA、DHAなど魚介由来は全ての死亡、CVD、がん、その他の原因の死亡、全てに予防的 ✅αリノレン酸は効果なし リノレン酸は体に良いけど、魚由来

Apr 30, 2021 · 1 share · 100 followers View post →
Pon|食と健康
@PonNutr · X

Nat commからオメガ3系脂肪酸に関するメタアナが出ていて、面白いです! ✅EPA、DPA、DHAなど魚介由来は全ての死亡、CVD、がん、その他の原因の死亡、全てに予防的 ✅αリノレン酸は効果なし リノレン酸は体に良いけど、魚由来

Apr 30, 2021 · 8 likes · 1 share · 2,792 followers View post →
Xtendlife
@XtendLifeNews · X

42,000 people can't be wrong. New meta study links levels of Omega 3s to longer lifespans. https://t.co/Bl6FVjKp8K

Apr 28, 2021 · 3 likes · 957 followers View post →
Carter Dunlap
@cwdunlap · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 25, 2021 · 18 shares · 470 followers View post →
BiohackersRadio
@BiohackersRadio · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 25, 2021 · 18 shares · 108 followers View post →
Jacob Tudor
@tudor_jacob · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 25, 2021 · 18 shares · 99 followers View post →
Fernpick
@Fernpick · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 25, 2021 · 18 shares · 428 followers View post →
SmartNutrition
@SmartNutrition1 · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 24, 2021 · 18 shares · 2,632 followers View post →
rupesh
@rupeshyadav · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 24, 2021 · 18 shares · 88 followers View post →
Pattibe
@pattiber1 · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 24, 2021 · 18 shares · 775 followers View post →
The Jeff Edwards
@JeffEdwardsMSRD · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 24, 2021 · 18 shares · 107 followers View post →
Brian Scott Edwards
@brianedwardsmd · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 24, 2021 · 18 shares · 1,888 followers View post →
Evan Thomas
@exploreabitmore · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 24, 2021 · 18 shares · 316 followers View post →
Eric Barker
@bakadesuyo · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 24, 2021 · 18 shares · 27,936 followers View post →
Roberto Medina
@otrebor_anidem · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 24, 2021 · 18 shares · 194 followers View post →
docceng
@docceng · X

RT @PeterAttiaMD: Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp…

Apr 24, 2021 · 18 shares · 1,820 followers View post →
Peter Attia
@PeterAttiaMD · X

Very high quality pooled meta-analysis of omega-3 fatty acids just published by Bill Harris et al. I’m still in the camp at higher levels of RBC EPA/DHA are important and target a minimum of 8% in my patients, and ideally north of 10%. https://t.co/UIrKOfCqru

Apr 24, 2021 · 151 likes · 18 shares · 515,692 followers View post →
Prof Andrew Scholey PhD
@Scholey · X

RT @andrews69141044: This is quite astounding! Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studi…

Apr 24, 2021 · 4 shares · 1,052 followers View post →
Ekrem Cem
@ekremcem · X

RT @andrews69141044: This is quite astounding! Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studi…

Apr 24, 2021 · 4 shares · 322 followers View post →
M. Lynn Cornish
@SisterSeaweed · X

RT @andrews69141044: This is quite astounding! Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studi…

Apr 24, 2021 · 4 shares · 4,334 followers View post →
Giovanni Turchini
@gioturchini · X

RT @andrews69141044: This is quite astounding! Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studi…

Apr 24, 2021 · 4 shares · 2,627 followers View post →
andrew sinclair
@andrews69141044 · X

This is quite astounding! Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies https://t.co/JLFbrm6ApM

Apr 24, 2021 · 3 likes · 4 shares · 41 followers View post →
Nick Krontiris
@nick_krontiris · X

RT @heniek_htw: PUFAs & Longevity ➡️ This meta-analysis including over 40,000 participants from 17 cohorts across 10 countries found that…

Apr 24, 2021 · 6 shares · 19,484 followers View post →
J P Fanton
@HealthyFellow · X

RT @heniek_htw: PUFAs & Longevity ➡️ This meta-analysis including over 40,000 participants from 17 cohorts across 10 countries found that…

Apr 23, 2021 · 6 shares · 25,965 followers View post →
Tɦιη Tωεɑκζ✨
@ThinTweaks · X

RT @nick_krontiris: Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies (open access) https://t…

Apr 23, 2021 · 3 shares · 743 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @nick_krontiris: Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies (open access) https://t…

Apr 23, 2021 · 3 shares · 1,396 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @heniek_htw: PUFAs & Longevity ➡️ This meta-analysis including over 40,000 participants from 17 cohorts across 10 countries found that…

Apr 23, 2021 · 6 shares · 1,396 followers View post →
htw
@heniek_htw · X

PUFAs & Longevity ➡️ This meta-analysis including over 40,000 participants from 17 cohorts across 10 countries found that high circulating levels of LC n-3 PUFAs, but not ALA, were associated with about a 15–18% lower risk of total mortality.

Apr 23, 2021 · 17 likes · 6 shares · 11,344 followers View post →
Nick Krontiris
@nick_krontiris · X

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies (open access) https://t.co/vHwlcm4hzx #nutrition #diet #PUFAs #Omega3 #CVD #cancer #longevity

Apr 23, 2021 · 4 likes · 3 shares · 19,484 followers View post →
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https://doi.org/10.1038/s41467-021-22370-2. Oil ω-3 Enrichment by Short-Path Distillation and In Vitro Bioactivity Evaluation. Hrebień-Filisińska, A., 2021 ...

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... x/semana) ou suplementação de 1 a 2 g/dia de EPA + DHA. Doi: 10.1038/s41467-021-22370-2. more. View all 3 comments. 4 days ago. leoborba12. •.

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... g/dia de EPA + DHA. Doi: 10.1038/s41467-021-22370-2. more. View all 3 comments. 2 days ago · leoborba12's profile picture · leoborba12. •.

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Omega 3 dalyvauja ilgame sąraše gyvybiškai svarbių organizmo ...
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Straipsnio nuoroda - https://doi.org/10.1038/s41467-021-22370-2. O kaip gauti Omega III pakankamai? Papildai gali būti atsakymas - apie tai ...

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... de peixes gordos de mar (3 x/semana) ou suplementação de 1 a 2 g/dia de EPA + DHA. Doi: 10.1038/s41467-021-22370-2".

Oct 21, 2025 View →
Omega III trūkumas prilygsta rūkymui. Mane šita antraštė labai ...
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... 10.1038/s41467-021-22370-2 O kaip gauti Omega III pakankamai? Papildai gali būti atsakymas - apie tai vėliau.".

Oct 12, 2025 View →
A suplementação de cálcio na gestação demonstrou reduzir o risco ...
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... g/dia de EPA + DHA. Doi: 10.1038/s41467-021-22370-2. more. View all 3 comments. 3 days ago · leoborba12's profile picture · leoborba12. •.

Apr 30, 2025 View →
As proteínas do sistema complemento fazem parte da ... - Instagram
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... g/dia de EPA + DHA. Doi: 10.1038/s41467-021-22370-2. more. View all 2 comments. 22 hours ago · leoborba12's profile picture · leoborba12. •.

Apr 9, 2025 View →
¿Estás usando un agonista GLP-1 como Ozempic, Wegovy o ...
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... 10.1038/s41467-021-22370-2. #NutriciónCientífica #GLP1 #Ozempic #Wegovy #Mounjaro #PérdidaDePeso #EfectoRebote #Nutricionista ...

Mar 13, 2025 View →
Há um lado bom que muitas pessoas não conhecem. E nem ...
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... g/dia de EPA + DHA. Doi: 10.1038/s41467-021-22370-2. more. View all 3 comments. 3 days ago · leoborba12's profile picture · leoborba12. •.

Dec 18, 2024 View →
Tal y como os cuento hoy, en salud hay cosas complejas, difíciles ...
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... 10.1038/s41467-021-22370-2) Erythrocyte long-chain omega-3 fatty acid levels are inversely associated with mortality and with incident ...

Jun 7, 2024 View →
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doi:10.1038/s41467-021-22370-2. Murphy MM, Barraj LM, Higgins KA. Healthy U.S.-style dietary patterns can be modified to provide increased ...

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Source: Nature Communications 22 April 2021 DOI : 10.1038/s41467-021-22370-2 Blood n-3 fatty acid levels and total and cause-specific ...

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Two new studies suggest that increasing omega-3 in our diet and ...
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... . Randomized controlled trial: 10.1038/s41380-021-01077-2 Meta-analysis: 10.1038/s41467-021-22370-2 #omega3 #longevity".

Apr 26, 2021 View →
Need more reasons to increase your Omega-3 EPA and DHA intake ...
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... . Randomized controlled trial: 10.1038/s41380-021-01077-2 Meta-analysis: 10.1038/s41467-021-22370-2 #omega3 #longevity".

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doi.org/10.1038/s41467-021-22370-2. Currently rated 5.0 by 2 people. Posted in: Medical Science News | Medical Research News. Comments (0).

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10.1038/s41467-021-22370-2. Keywords. /Life sciences/Biochemistry/Biomolecules/Fatty acids; /Applied sciences and engineering/Risk management ...

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