Neurosci Bull August 2021 PMID 33909242

Hypothalamic-Pituitary-End-Organ Axes: Hormone Function in Female Patients with Major Depressive Disorder.

Yuncheng Zhu, Xiaohui Wu, Rubai Zhou, Oliver Sie, Zhiang Niu, Fang Wang, Yiru Fang

Mentions

3
Peak: 2 in Jul 2024
across 2 sources since Aug 2021

Extended reach

273
potential audience

Total likes

0

Video views

197

Mentions per month

Aug 2021 – Jul 2024

Where it's discussed

  • YouTube2 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

The references focus on artistic symbolism, such as the image related to melancholic temperament, which shows a moderate engagement with the topic but lacks detailed scientific discussion. The tone suggests a superficial appreciation rather than an intense or impactful discourse on the hormonal interactions in MDD.

AgreementNeither agree nor disagree

The discussion mostly recognizes the interconnectedness of hormonal systems in female depression but does not strongly agree or disagree with the publication’s conclusions.

InterestModerate interest

The mention of the melancholic theme and symbolism indicates a mild curiosity, but overall interest in the scientific content remains modest.

EngagementNeutral engagement

Posts contain some reference to the article's themes, but there is limited in-depth discussion or critical analysis.

ImpactNeutral impact

The discussion does not demonstrate that it has significantly influenced broader perspectives or clinical practices.

Abstract in brief

  • The text discusses how three key hormonal systems—the hypothalamic-pituitary-adrenal (HPAA), hypothalamic-pituitary-thyroid (HPTA), and hypothalamic-pituitary-gonadal (HPGA) axes—are interconnected and play roles in female patients with Major Depressive Disorder (MDD), influencing neuroendocrine and immune functions.
  • Women with MDD experience fluctuations in hormone levels such as glucocorticoids, thyroid hormones, and reproductive steroids, which can disrupt hormonal feedback processes and receptor functioning, potentially impairing mood regulation and physiological stability.
  • The review highlights that due to the structural similarities among steroid hormones, these endocrine axes can interact competitively at receptor sites, especially between the HPAA and HPGA, complicating their individual effects and contributing to the hormonal imbalances observed in female MDD patients.]

Top posts

Most liked on X and Bluesky
Fei Dong
@daydreamerscent · X

In this cover image, the theme of "Daiyu Burying Fallen Flower Petals" (黛玉葬花)is used to express the melancholic temperament of female patients. #NeuroscienceBulletin. You can find this article here: https://t.co/Sfh3eqPsj2. https://t.co/47CBcW8NfT

Aug 10, 2021 · 77 followers View post →

All mentions

Fei Dong
@daydreamerscent · X

In this cover image, the theme of "Daiyu Burying Fallen Flower Petals" (黛玉葬花)is used to express the melancholic temperament of female patients. #NeuroscienceBulletin. You can find this article here: https://t.co/Sfh3eqPsj2. https://t.co/47CBcW8NfT

Aug 10, 2021 · 77 followers View post →