Front Bioeng Biotechnol April 2021 PMID 33937212

Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics.

Alejandro Carnicer-Lombarte, Shao-Tuan Chen, George G Malliaras, Damiano G Barone

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Mentions

63
Peak: 31 in Mar 2021
across 4 sources since Mar 2021

Extended reach

57,566
potential audience

Total likes

319

Video views

12,603

Mentions per month

Mar 2021 – Dec 2025

Where it's discussed

  • X / Twitter56 posts
  • News4 articles
  • YouTube2 videos
  • Facebook1 posts

AI synopsis

What people are saying

The collective discussions highlight the importance of understanding the immune response to implants, with users referencing the challenges of long-term biomaterial implantation and potential strategies to overcome FBR, such as material modifications and drug use. Words like 'challenge,' 'problem,' and 'potential' signal a serious tone, emphasizing both interest and perceived significance of the study.

AgreementModerate agreement

Most posts acknowledge the challenges posed by foreign body reactions, indicating support for the article's content.

InterestHigh interest

Discussion participants show high curiosity, referencing technical details and potential solutions, reflecting strong engagement with the topic.

EngagementModerate engagement

Some users deepen the discussion by mentioning related research, personal experiences, and potential future implications, demonstrating moderate but meaningful interaction.

ImpactHigh impact

The posts suggest that this research is perceived as highly relevant, with comments about its significance for medical technology and patient outcomes, implying a high perceived impact.

Abstract in brief

  • The foreign body reaction (FBR) occurs when the immune system reacts to implanted biomaterials, leading to inflammation, fibrosis, and the formation of a barrier around the implant, which can disrupt its function over time.
  • This reaction is especially problematic in nerve neuroprosthetics, which require precise and stable interfaces with nerve tissue for effective electrical communication, making long-term implant success challenging.
  • Strategies such as modifying material properties, using drugs, or employing biodegradable materials are being explored to reduce FBR and enhance the durability and performance of nerve neuroprosthetic devices.]

Top posts

Most liked on X and Bluesky
BioelectronicsLab
@BioelectronicsL · X

Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics @baronedg @AlejCarnicer @shao_tuan @Cambridge_Eng https://t.co/XTgjjHJs4z

Mar 19, 2021 · 32 likes · 6 shares · 4,148 followers View post →
mesh injured patients
@SusanMorgan19 · X

https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Foreign Body Response This fact

Feb 22, 2024 · 10 likes · 8 shares · 2,588 followers View post →
Damiano G. Barone
@baronedg · X

Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics https://t.co/Ez74CWsqYH @BioelectronicsL @AlejCarnicer @shao_tuan @GeorgeMalliaras @CATO_Cambridge @NIHRresearch

Apr 15, 2021 · 10 likes · 1 share · 1,455 followers View post →
Frontiers - Bioengineering and Biotechnology
@FrontBioeng · X

While implantable technologies have extensively evolved over the last few decades, the clinical use of implants continues to be severely hampered by the challenges arising from the hostile environment of the body. Read more here ➡️ https://t.co/4zK3hmcm7L https://t.co/yXA2fUVCsb

Jun 9, 2023 · 5 likes · 3,921 followers View post →
mesh injured patients
@SusanMorgan19 · X

@BeedhamVicky I like writing to these #gaslighting #doctors with known research. #mesh causes chronic illness The implantation of any foreign material into the body leads to the development of an inflammatory and fibrotic process—the foreign body reaction (FBR). https://t.co/LZ9zmSzfzw

Aug 26, 2021 · 2 likes · 3 shares · 2,588 followers View post →
charity479
@charity479 · X

Frontiers | Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics | Bioengineering and Biotechnology https://t.co/jMaFTcaOK8

Nov 23, 2021 · 1 like · 2,368 followers View post →

All mentions

Mesh Problems
@Mesh_Problems · X

RT @SusanMorgan19: https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Forei…

Dec 7, 2025 · 8 shares · 1,939 followers View post →
Morton
@Mortonmesh01 · X

RT @SusanMorgan19: https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Forei…

Dec 5, 2025 · 8 shares · 51 followers View post →
Janis Kay Urban
@JanUrban12 · X

RT @SusanMorgan19: https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Forei…

Dec 5, 2025 · 8 shares · 2,221 followers View post →
Hannah Bentley
@hannaht1271 · X

RT @SusanMorgan19: https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Forei…

Dec 4, 2025 · 8 shares · 189 followers View post →
Louise White
@LouiseWhitemesh · X

RT @SusanMorgan19: https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Forei…

Dec 4, 2025 · 8 shares · 60 followers View post →
mesh injured patients
@SusanMorgan19 · X

RT @SusanMorgan19: https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Forei…

Dec 4, 2025 · 8 shares · 2,588 followers View post →
chrissy shipley
@chrissyshipley · X

RT @SusanMorgan19: https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Forei…

Feb 22, 2024 · 8 shares · 314 followers View post →
paula Hampson
@phampson5 · X

RT @SusanMorgan19: https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Forei…

Feb 22, 2024 · 8 shares · 7 followers View post →
mesh injured patients
@SusanMorgan19 · X

https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Foreign Body Response This fact

Feb 22, 2024 · 10 likes · 8 shares · 2,588 followers View post →
mesh injured patients
@SusanMorgan19 · X

https://t.co/nV22SvPBN2 Let’s be very clear - no patient admitted for #pelvic #mesh #implant was ever informed of Foreign Body Response This fact

Feb 22, 2024 · 2,588 followers View post →
Frontiers - Bioengineering and Biotechnology
@FrontBioeng · X

While implantable technologies have extensively evolved over the last few decades, the clinical use of implants continues to be severely hampered by the challenges arising from the hostile environment of the body. Read more here ➡️ https://t.co/4zK3hmcm7L https://t.co/yXA2fUVCsb

Jun 9, 2023 · 5 likes · 3,921 followers View post →
Frontiers - Bioengineering and Biotechnology
@FrontBioeng · X

Long-term implantation of medical devices, such as nerve neuroprosthetics, faces a great challenge presented by the foreign body reaction, seeing as they rely on tight interfacing between nerve tissue and electrodes. Read more ➡️ https://t.co/5SACzvAyET https://t.co/jE9yYyJXh9

Feb 20, 2023 · 3,921 followers View post →
Human Adaptation
@HumanAdapt · X

@elonmusk First, your body does not like foreign objects inside the body. Your body's immune system will constantly send leukocytes to the location to try and remove them. Because of that, the implant quickly degrades, leading to toxic chemical exposures. https://t.co/m6GLYA5cMM

Nov 17, 2022 · 7 followers View post →
blueskies
@blueskynicetry · X

@Siedeh1 @AlpacaAurelius @CryptoDora https://t.co/aAX8WUfbhg

Jul 2, 2022 · 180 followers View post →
Shannon Patrick Ramos
@shannonpatrick · X

@jamessimsiv @Philly852 I read that article, wow biofuel cell w/a supercapacitor -they seem pretty sure they can just add & create in humans like legos. I had 3lvl spinal fusion but later had titanium rods a bit larger than #2 pencil & 6 lag bolts removed -hardware didn't take https://t.co/ppJTBmwNBy

Apr 4, 2022 · 1 like · 1,361 followers View post →
K Anders ⛵️
@Kimmi00ag · X

@JordanChariton I think it will never work. Unless they come up with a substance the body won’t attack and start coating with material like a pearl around a sand grain. https://t.co/Kf98S9x9Sw

Jan 24, 2022 · 345 followers View post →
charity479
@charity479 · X

Frontiers | Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics | Bioengineering and Biotechnology https://t.co/jMaFTcaOK8

Nov 23, 2021 · 1 like · 2,368 followers View post →
Linda Garland
@lindajane57821 · X

RT @SusanMorgan19: @BeedhamVicky I like writing to these #gaslighting #doctors with known research. #mesh causes chronic illness The imp…

Aug 27, 2021 · 3 shares · 183 followers View post →
Janis Kay Urban
@JanUrban12 · X

FYI: Frontiers | Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics | Bioengineering and Biotechnology https://t.co/be4Vxigjk0

Aug 27, 2021 · 2,221 followers View post →
Sally Maddocks
@maddocks_sally · X

RT @SusanMorgan19: @BeedhamVicky I like writing to these #gaslighting #doctors with known research. #mesh causes chronic illness The imp…

Aug 26, 2021 · 3 shares · 967 followers View post →
Paula Goss
@Paula_Goss · X

RT @SusanMorgan19: @BeedhamVicky I like writing to these #gaslighting #doctors with known research. #mesh causes chronic illness The imp…

Aug 26, 2021 · 3 shares · 1,200 followers View post →
mesh injured patients
@SusanMorgan19 · X

@BeedhamVicky I like writing to these #gaslighting #doctors with known research. #mesh causes chronic illness The implantation of any foreign material into the body leads to the development of an inflammatory and fibrotic process—the foreign body reaction (FBR). https://t.co/LZ9zmSzfzw

Aug 26, 2021 · 2 likes · 3 shares · 2,588 followers View post →
Frontiers - Bioengineering and Biotechnology
@FrontBioeng · X

New Research: Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics https://t.co/Z7IolaLuJR #bioengineering #biotech

Apr 15, 2021 · 3,921 followers View post →
Russell Hamilton @drrshamilton.bsky.social
@drrshamilton · X

RT @baronedg: Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics https://t.co/Ez74CWsqYH @Bioelectron…

Apr 15, 2021 · 1 share · 556 followers View post →
Damiano G. Barone
@baronedg · X

Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics https://t.co/Ez74CWsqYH @BioelectronicsL @AlejCarnicer @shao_tuan @GeorgeMalliaras @CATO_Cambridge @NIHRresearch

Apr 15, 2021 · 10 likes · 1 share · 1,455 followers View post →
Gilbert Research Center
@GILBERTResearch · X

RT @BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics @baronedg @AlejCarnicer @shao…

Mar 20, 2021 · 6 shares · 29 followers View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from rochford_amy: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve

Mar 20, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from rochford_amy: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejC

Mar 20, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from rochford_amy: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 20, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from rochford_amy: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 20, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from rochford_amy: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 20, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from rochford_amy: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 20, 2021 View post →
Amy Rochford
@rochford_amy · X

RT @BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics @baronedg @AlejCarnicer @shao…

Mar 20, 2021 · 6 shares · 797 followers View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from hugoko: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnice

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from hugoko: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from hugoko: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from hugoko: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from hugoko: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from TanyaradzwaMa19: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from KawanMalak: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from YawAnsongSnr: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
Yaw Ansong Snr
@YawAnsongSnr · X

RT @BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics @baronedg @AlejCarnicer @shao…

Mar 19, 2021 · 6 shares · 239 followers View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from KawanMalak: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from TanyaradzwaMa19: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from AlejCarnicer: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejC

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from AlejCarnicer: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from AlejCarnicer: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from AlejCarnicer: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
Alejandro Carnicer Lombarte
@AlejCarnicer · X

RT @BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics @baronedg @AlejCarnicer @shao…

Mar 19, 2021 · 6 shares · 262 followers View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from baronedg: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from baronedg: RT BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao…

Mar 19, 2021 View post →
Damiano G. Barone
@baronedg · X

RT @BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics @baronedg @AlejCarnicer @shao…

Mar 19, 2021 · 6 shares · 1,455 followers View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from neuroprostheti2: See tweet from BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao_tuan Cambridge_Eng https://t.co/2pBeXGuP95

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from neuroprostheti2: See tweet from BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao_tuan Cambridge_Eng https://t.co/2pBeXGuP95

Mar 19, 2021 View post →
@neuroprosthetics
@neuroprostheti2 · X

See tweet from BioelectronicsL: Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics baronedg AlejCarnicer shao_tuan Cambridge_Eng https://t.co/2pBeXGuP95

Mar 19, 2021 View post →
BioelectronicsLab
@BioelectronicsL · X

Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics @baronedg @AlejCarnicer @shao_tuan @Cambridge_Eng https://t.co/XTgjjHJs4z

Mar 19, 2021 · 32 likes · 6 shares · 4,148 followers View post →
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