This is also not the first paper to demonstrate this finding that afucosylated antibodies in COVID = badness. For instance, while looking for that paper I also found this paper with remarkably similar findings: https://t.co/QS1l5iJEDd
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages.
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May 2021 – Aug 2024Where it's discussed
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X / Twitter231 posts
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News126 articles
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Reddit4 posts
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YouTube3 videos
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Facebook2 posts
AI synopsis
What people are saying
The discussions strongly emphasize the importance of antibody features, such as low fucosylation and high titers, in driving inflammation and disease severity, often referencing experimental results, mechanisms like macrophage activation, and therapeutic options like fostamatinib. The tone is scientifically detailed and highlights consensus on the article's relevance, indicated by phrases like 'super-important', 'groundbreaking', and calls for broader dissemination, reflecting high levels of interest and perceived impact.
Most discussions support the key findings, emphasizing the significance of antibody characteristics like low fucosylation in promoting inflammation.
Posts demonstrate high engagement with the topic, referencing specific mechanisms, potential treatments such as fostamatinib, and implications for COVID-19 severity.
Many contributions delve into scientific details, compare related studies, and discuss therapeutic strategies, indicating deep involvement.
The widespread sharing of research findings and calls to action suggest strong perceived importance for understanding and potentially mitigating severe COVID-19 responses.
Abstract in brief
- * The study found that high levels of specific antibodies (anti-spike IgG) in the serum of severely ill patients lead to excessive inflammatory responses in alveolar macrophages, contributing to worse outcomes in COVID-19.
- * This inflammatory response is driven by antibody characteristics, such as low fucosylation, and can be targeted for treatment; the study suggests that using fostamatinib may help reduce this harmful inflammation.
Top posts
Most liked on X and Bluesky@UnrollThread Updates to my
Following papers all arrive at two things 1. Proinflammatory response from overactive immune system 2. Endothelial injury and microthrombosis [1]: https://t.co/qbiF8G3IOm [2]: https://t.co/fKAHzC9oQ9 [3]: https://t.co/mCzfkZMAAo [4]: https://t.co/r9VhXvlanX
@philamillan @mirwijn @Luketheduke1960 @SteveGPickering @Marc_Veld @GVDBossche @PAlexanderPhD @BretWeinstein @delbigtree @DrJohnCampbell3 @DLoesch Your research is missing key data on the role of afucosylated antibodies and anti-interferon antibodies in severe COVID cases. https://t.co/lw4CrLAkWp https://t.co/2d6s2KYVQR Will you be answering my question regarding your claims of vaccines driving the emergence of variants?
@bardinidouglas Aí assim nos remetemos de volta ao estudo do ADI (antibody dependent inflammation). https://t.co/KNpWGwQj85
@mab_sp125 @mellziland Me preocupei c/ idosos qdo vi este artigo sobre ADI (antibody dependent inflammation) e relação com doença grave. Uma quantidade menor de CD8 já é normal em idosos. E ativar CD8 não é bem o forte dessa vacina. O combate intracelular fica prejudicado. https://t.co/VQBP0IAYtl
All mentions
Understanding Severe COVID-19: Abnormal Antibody Responses and Inflammation
Why do COVID-19 patients become critically ill around 15 weeks after infection? This animation summarizes research showing that abnormal antibody responses trigger excessive lung inflammation, blood vessel damage, and…
COVID-19 Antibody Response and Inflammation in Severe Cases
Dr Jeroen den Dunnen and Prof Menno de Winter from Amsterdam UMC discuss their research on COVID-19, focusing on how specific antibody characteristics influence inflammation and disease severity, with potential targeted…
Impact of Antibody Characteristics on COVID-19 Inflammation and Severity
Patients with severe COVID-19 often experience critical illness during seroconversion when antibodies are produced. High levels of anti-spike IgG with low fucosylation promote inflammation by alveolar macrophages…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @DrDenDunnen: Super-short summary: We found (1) Why we become so sick (-> aberrant antibodies against Spike) (2) A drug that can counter…
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/K1N6LmrbUN
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @johnjljacobs: @UnrollThread Updates to my
@UnrollThread Updates to my
RT @theyareus2: @ClareCraigPath Study below .. “The finding that negative nucleocapsid antibody testing was associated with strongly increa…
@Natalie70536543 @JamesfWells @Berm_1984 @DrAseemMalhotra This study found that negative nucleocapsid antibody testing was associated with strongly increased or generalized viral dissemination in fully vaccinated cases- these patients were no longer able to elicit a primary response vs the nucleocapsid protein https://t.co/T69wKwLw0S
@ClareCraigPath Study below .. “The finding that negative nucleocapsid antibody testing was associated with strongly increased or generalized viral dissemination in fully vaccinated cases .while spike-specific antibodies were often present or even boosted to high titers” https://t.co/T69wKwLw0S
@SnupSnus @gadboit Antibody-dependent inflammation (ADI) is used in the literature. Example: https://t.co/7zuseDZvZv
@kellywind @CovidisBananas @realZenelan @juli_bg_bs Antibody dependent inflammation, associated with afucosylated IgG. I think this is the best explanation for VAED for SC1 and possibly also measles and RSV. https://t.co/NuAv2M4Lmn
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
@vieil_garde_ph @EricBillyFR @wargonm @LacombeKarine1 https://t.co/PtFQVGd10C
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @Debunk_the_Funk: @philamillan @mirwijn @Luketheduke1960 @SteveGPickering @Marc_Veld @GVDBossche @PAlexanderPhD @BretWeinstein @delbigtr…
@philamillan @mirwijn @Luketheduke1960 @SteveGPickering @Marc_Veld @GVDBossche @PAlexanderPhD @BretWeinstein @delbigtree @DrJohnCampbell3 @DLoesch Your research is missing key data on the role of afucosylated antibodies and anti-interferon antibodies in severe COVID cases. https://t.co/lw4CrLAkWp https://t.co/2d6s2KYVQR Will you be answering my question regarding your claims of vaccines driving the emergence of variants?
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
{2} Anti-spike IgG may activate platelets through FcγRIIa, which would provide a direct way of plt activation in addition to the indirect one by MΦs & pulmonary endothelium (Fig.5B,C‥), further promoting microvascular thrombosis. #SARSCoV2 https://t.co/KHJ2iNxnhb(May 10) ref. https://t.co/b9mpcE4LlY
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
{6} Activation of immune cells by IgG requires immune complex formation by binding of IgG to its cognate Ag. FcγRIII be the primary receptor responsible for the enhanced cytokine production by aberrant IgG glycosylation (↓fuc,↑gal) (Fig.6C). #SARSCoV2 https://t.co/fPInkeJ5SI https://t.co/5vjGEZOiNg
{4} Anti-spike IgG* titers rapidly increase after seroconversion followed by a gradual decline. Only the first wave of * displays aberrant Fc glycosylation (↓fuco & ↑gala), which rapidly normalizes in the following days to weeks (Fig. 4F). #SARSCoV2 https://t.co/5JwKzT1Dhs↓ https://t.co/mLdoSMxtvB
{5} From {4}'s two parameters, the induction of excessive inflammation (Figs) by *anti-spike IgG is likely to occur in the days right after seroconversion, when * titers are high & Fc glycosylation is most aberrant (↓↓fucose & ↑↑galactose). #SARSCoV2 https://t.co/5JwKzT1Dhs https://t.co/2a7gGLj2Vb
{1} Extreme activation of ‘Fc effector functions’ by afucosylation needs to be prevented, while ‘ ’ should remain partially intact to provide optimal therapeutic protection. ADI appears to → ↑↑inflammation on infection with both SARSCoV1 & #SARSCoV2. https://t.co/5JwKzT1Dhs https://t.co/2JoSIyaeEt
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
@boulware_dr @hattenhof @US_FDA @humanigen @LancetRespirMed any thoughts on fostamatinib? ph2 results + UVA research that first identified it as a possible treatment https://t.co/Rj03DA34VV https://t.co/bviwCOBZP9
RT @RealThomasWest: Fostamatinib completely prevented covid-19 cytokine storm. https://t.co/Rj03DA34VV
Fostamatinib completely prevented covid-19 cytokine storm. https://t.co/Rj03DA34VV
RT @ENirenberg: This is also not the first paper to demonstrate this finding that afucosylated antibodies in COVID = badness. For instance,…
RT @Girish_cbe: Following papers all arrive at two things 1. Proinflammatory response from overactive immune system 2. Endothelial injury a…
A much-replicated finding is that severe disease progression with SCV2 infection is associated with early induction of a high proportion of afucosylated IgG: https://t.co/XMZC0CTF4a https://t.co/3fofmx9jf6 https://t.co/xfOatknS4D https://t.co/DIyRFOd8lX
RT @Girish_cbe: Following papers all arrive at two things 1. Proinflammatory response from overactive immune system 2. Endothelial injury a…
RT @Girish_cbe: Following papers all arrive at two things 1. Proinflammatory response from overactive immune system 2. Endothelial injury a…
RT @ENirenberg: This is also not the first paper to demonstrate this finding that afucosylated antibodies in COVID = badness. For instance,…
RT @Girish_cbe: Following papers all arrive at two things 1. Proinflammatory response from overactive immune system 2. Endothelial injury a…
RT @ENirenberg: This is also not the first paper to demonstrate this finding that afucosylated antibodies in COVID = badness. For instance,…
RT @Girish_cbe: Following papers all arrive at two things 1. Proinflammatory response from overactive immune system 2. Endothelial injury a…
RT @Girish_cbe: Following papers all arrive at two things 1. Proinflammatory response from overactive immune system 2. Endothelial injury a…
RT @ENirenberg: This is also not the first paper to demonstrate this finding that afucosylated antibodies in COVID = badness. For instance,…
3. High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/mCzfkZMAAo 4. Complement activation induces excessive T cell cytotoxicity in severe COVID-19 https://t.co/r9VhXvlanX
This is also not the first paper to demonstrate this finding that afucosylated antibodies in COVID = badness. For instance, while looking for that paper I also found this paper with remarkably similar findings: https://t.co/QS1l5iJEDd
Following papers all arrive at two things 1. Proinflammatory response from overactive immune system 2. Endothelial injury and microthrombosis [1]: https://t.co/qbiF8G3IOm [2]: https://t.co/fKAHzC9oQ9 [3]: https://t.co/mCzfkZMAAo [4]: https://t.co/r9VhXvlanX
@Anisopterid Severe Covid cases tend to go south just as large quantities of IgG are being produced, especially afucosylated IgG (which is associated with ADCC). So I doubt that lack of opsonization is leading to ab-independent complement activation. But you are ... https://t.co/NuAv2M4Lmn
RT @kachelme1: I appear to be on a fucosylation binge, https://t.co/06yNePVfqS.
RT @kachelme1: I appear to be on a fucosylation binge, https://t.co/06yNePVfqS.
I appear to be on a fucosylation binge, https://t.co/06yNePVfqS.
@bardinidouglas Aí assim nos remetemos de volta ao estudo do ADI (antibody dependent inflammation). https://t.co/KNpWGwQj85
RT @DrDenDunnen: Super-short summary: We found (1) Why we become so sick (-> aberrant antibodies against Spike) (2) A drug that can counter…
@LeGrandBlond666 @KheyTorique @biolib59 @sarahmel2000 @PhilCourchesne Ah bon? C'est écrit où? en terme de crédibilité, vous devriez faire plus attention... voici pour la mienne https://t.co/hGYgvJkM0U https://t.co/qAl1VNbdO3 https://t.co/IwBZiLc6aU https://t.co/lZ2hTXh1Ta https://t.co/UhbHy0Ct4a https://t.co/P9YT9OKsF1 https://t.co/CvWvzkUewB
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @DrDenDunnen: Super-short summary: We found (1) Why we become so sick (-> aberrant antibodies against Spike) (2) A drug that can counter…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
@DebunkMoutarde @GuigoDalphinus @jm_desp c'est fait... https://t.co/u1aPQSY5V0 https://t.co/RzVt63oxca https://t.co/mKIDodfaWp https://t.co/hGYgvJkM0U https://t.co/qAl1VNbdO3 https://t.co/IwBZiLc6aU https://t.co/lZ2hTXh1Ta https://t.co/UhbHy0Ct4a
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
「SARS-CoV-2に対する、高力価、低フコシルの初期IgG抗体が肺マクロファージによる炎症を促進」 半年前の論文だけど、自分が最近見た中では最重要論文だと思う Syk阻害薬のフォスタマチニブによって炎症反応を打ち消せることにも言及 https://t.co/zaH1CWZyCa
https://t.co/uPecQIK4fY https://t.co/irf36mjEiU
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @notvanshnarang: awakenindiamvmt: RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine dr…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
@awakenindiamvmt @MoHFW_INDIA @PMOIndia @narendramodi @mansukhmandviya @CMOTamilnadu @CMMadhyaPradesh @CMODelhi @CMOMaharashtra @ArvindKejriwal Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/kwb4Kbfc6X @MoHFW_INDIA @PMOIndia @narendramodi @mansukhmandviya @CMOTamilnadu @CMMadhyaPradesh @CMODelhi @CMOMaharashtra @ArvindKejriwal #NoVaccineMandates
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
awakenindiamvmt: RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/GoGdpfvW2W @MoHFW_INDIA @PMOIndia @narendramodi @mansukhmandviya @CMOTamilnadu @CMMadhyaPradesh @CMODe… https://t.co/fVdqavAVqb
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @awakenindiamvmt: Overreaction of immune system more dangerous than the virus! STOP the #Vaccine drive! Think AYUSH!! https://t.co/A8Cds…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/i9UpydxOCz
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
https://t.co/ifLZQBg7gL
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
@victorfyt @IrlandesMaynard Existe lo que se llama "mejora dependiente de anticuerpos" (ADE). Las vacunas pueden provocar eso. No te fies de los datos de Israel, pues venían se un pico muy alto y mucha sobre Mortalidad. https://t.co/WJQQgrDY5B
High titers and low #fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by #alveolar macrophages https://t.co/Ayovq42MzD
@waggybiomed @luizacaires3 E isso tudo traz implicâncias importantes, como possibilidade daquilo que acabou ganhando nome de ADI (antibody dependent inflammation). https://t.co/VQBP0IAYtl
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/F5n3IKDb7a https://t.co/aNGcXDXnXg
RT @GerszonT: #fostamatinib $RIGL #Covid19 "we demonstrate that the inflammatory response induced by anti-spike IgG can be specifically cou…
#fostamatinib $RIGL #Covid19 "we demonstrate that the inflammatory response induced by anti-spike IgG can be specifically counteracted by fostamatinib, an FDA- and EMA-approved therapeutic small molecule inhibitor of Syk kinase." https://t.co/zurnFoRT20 https://t.co/JX613BfFci
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages Science Translational Medicine 11 May 2021 https://t.co/3xIUwDs8CT
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages. https://t.co/yRie16MQOb
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
@mab_sp125 @mellziland Me preocupei c/ idosos qdo vi este artigo sobre ADI (antibody dependent inflammation) e relação com doença grave. Uma quantidade menor de CD8 já é normal em idosos. E ativar CD8 não é bem o forte dessa vacina. O combate intracelular fica prejudicado. https://t.co/VQBP0IAYtl
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @JenT47775608: @amandalily1107 @Maggie12409794 文章在这里,忘了发。。
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/V7QmjjXGLo
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages.
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/FWhCof0EmA
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
RT @gadboit: Thread on the super-important new paper from Hoepel et al about Antibody Dependent Inflammation (ADI), and its significance fo…
High titers and low fucosylation of early human anti #SARS_CoV_2 IgG promote inflammation by alveolar macrophages https://t.co/GN5lnMTIAS https://t.co/jmr9PGeVzg
RT @FahdAlMulla: #COVID19 High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages…
#COVID19 High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/13YosNmtG5
RT @Azeria64Azeria: COVID-19 : L'aggravation de la maladie au moment de la séroconversion. High titers and low fucosylation of early human…
RT @Azeria64Azeria: COVID-19 : L'aggravation de la maladie au moment de la séroconversion. High titers and low fucosylation of early human…
COVID-19 : L'aggravation de la maladie au moment de la séroconversion. High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/1BX6T4snSu
Researchers @ AmsterdamUMC have discovered why patients become seriously ill after being infected with the coronavirus https://t.co/8AfH1NRbRg High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/xwI79Rs9Ri https://t.co/pWLHaQQI95
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages | Science Translational Medicine https://t.co/YQWpRbZc1a
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/7q0ied0CJ1
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages | Science Translational Medicine https://t.co/oJpJaTqpdg
RT @Aller_MD: “High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages” https://t.…
RT @Aller_MD: “High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages” https://t.…
RT @Aller_MD: “High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages” https://t.…
“High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages” https://t.co/gdPG8V6eaa https://t.co/owWLF5EEDr
New article: High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/3fDceWLdHT #coronavirus #COVID19 #2019ncov https://t.co/M3JKO0203M
I cannot believe that this is not widely shared. https://t.co/mSeDl8Kjh4
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/ZLhxF7z3SS
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/JYp3jt0kZO
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/HFYsBWYIH0
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/c71qm2pXC9
Cool thread and even cooler paper @ScienceTM @DrDenDunnen & friends on how not all #antibodies are created equal during #COVID19… and how #Ab #fucosylation can drive #macrophages crazy and super severe pathology… Congrats! https://t.co/vnUkWEvOes https://t.co/1yL04R3bz5
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/UIl05DbQCY
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/uKNLxvhPcz
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/upRaf9cDxP
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages https://t.co/0Wd1rCa6Xz
High titers and low #fucosylation of early human anti-#SARS-CoV-2 IgG promote #inflammation by #alveolar #macrophages: https://t.co/u8buKJmzey
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages | Science Translational Medicine https://t.co/m5EGa0SjAz
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