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The discussions consistently express recognition of the heavy economic and social burden of treatment-resistant depression, with phrases like 'significant impact' and 'urgent need for better management' signaling high interest and perceived importance. Participants engage thoughtfully, referencing the broad societal implications and potential for policy change, which underscores the high impact and moderate engagement levels.
Most discussions acknowledge the significance of the research findings about the high prevalence and costs of treatment-resistant depression, highlighting its importance.
Participants show strong interest in the topic, often referencing societal and economic impacts, indicating engagement with the subject matter.
Several contributions delve into the implications for policy and treatment, reflecting a moderate depth of engagement beyond surface-level reactions.
The discussions suggest that the publication could influence future research, policies, and treatments related to depression, emphasizing its societal significance.
REFERENCES Zhadanava M, Oilon, D,Ghelerter I, et al. (2021). The prevalence and national burden of treatment-resistant depression and major depressive disorder in the United States. Journal of Clinical Psychiatry; 82(2):20m13699
The pharmaceutical industry has failed our most vulnerable patients and in the current mental health crisis its important that we understand how we got here. This is my first science video on this channel and it took me…
This video explores the development of esketamine as a nasal spray approved in 2019 for treatment-resistant depression, covering molecular properties, animal models, clinical trials, and the FDA approval process.
REFERENCES Zhadanava M, Oilon, D,Ghelerter I, et al. (2021). The prevalence and national burden of treatment-resistant depression and major depressive disorder in the United States. Journal of Clinical Psychiatry; 82(2):20m13699
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