Front Immunol October 2021 PMID 33995404

Trans Fatty Acid Intake Induces Intestinal Inflammation and Impaired Glucose Tolerance.

Takuro Okamura, Yoshitaka Hashimoto, Saori Majima, Takafumi Senmaru, Emi Ushigome, Naoko Nakanishi, Mai Asano, Masahiro Yamazaki, Hiroshi Takakuwa, Masahide Hamaguchi, Michiaki Fukui

Mentions

76
Peak: 32 in Sep 2023
across 5 sources since Apr 2021

Extended reach

4,586,231
potential audience

Total likes

64,197

Video views

3,338,735

Mentions per month

Apr 2021 – Jul 2025

Where it's discussed

  • X / Twitter59 posts
  • YouTube8 videos
  • News5 articles
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The overall tone reflects strong agreement and interest, with users often citing specific health outcomes like diabetes and fatty liver, and discussing the broader implications for diet and public health. Words like 'significantly increased,' 'microbiome change,' and 'impairs glucose tolerance' contribute to a serious and engaged tone, underscoring the perceived importance of the study.

AgreementStrong agreement

Most discussions support the findings, emphasizing the negative health effects of trans fats and their role in inflammation and metabolic issues.

InterestHigh interest

The social discussions show high interest, with many users referencing metabolic diseases, gut health, and dietary advice, indicating active engagement with the topic.

EngagementHigh engagement

Comments include detailed references to scientific studies, health implications, and personal health experiences, reflecting deep engagement.

ImpactHigh impact

The widespread concern about trans fats and the health consequences suggests these discussions view the research as having considerable impact on dietary habits and health awareness.

Abstract in brief

  • High intake of trans fatty acids in mice leads to increased blood sugar levels, fatty liver, and intestinal inflammation, indicating negative health effects.
  • The study found that diets high in trans fats increased the expression of certain immune cells and decreased protective factors like IL22 in the gut, which may contribute to inflammation.
  • Compared to saturated fats, trans fatty acids worsened metabolic conditions such as diabetes and fatty liver, highlighting their harmful impact on health.]

Top posts

Most liked on X and Bluesky
Cristina Dragani
@CristinaDragani · X

A #diet high in trans fatty acids (chemically altered vegetable oils) significantly increased blood #glucose levels, #diabetes risk, and fatty liver, in a study in mice. It also changes the gut #microbiome, increasing populations of bad #bacteria. https://t.co/Qt8BqmuVUp https://t.co/K5uryanAuP

Jun 1, 2021 · 13 likes · 4 shares · 10,820 followers View post →
François Booream
@BooraemFrancois · X

@EthicalSkeptic I tend to think its probably a top predator ie round up, but with cascading ripples .. cleaning products that promise to kill "99% of germs", over use of antibiotics/medication in general. oxidised vegetable oils etc. dont forget trans fats.. https://t.co/vvJ3peJOg8

May 3, 2022 · 13 likes · 1 share · 729 followers View post →
أ.د.فهد الخضيري
@DrAlkhodairy · X

Trans Fatty Acid Intake Induces Intestinal Inflammation and Impaired Glucose Tolerance - PMCالدهون المتحولة تدعم التهابات الأمعاء وتدعم مقاومة الأنسولين ، فقللوا منها او اتركوها https://t.co/M4aOzlMIPh

Dec 1, 2023 · 9 likes · 1 share · 1,117,573 followers View post →
ساره RDN
@sarahrdn8 · X

https://t.co/CiD7Vod3xZ

Jun 26, 2023 · 6 likes · 8,990 followers View post →
✨ Sophie Gironi ✨
@SophieGironi · X

Et si on arrêtait de manger de la

Apr 27, 2022 · 3 likes · 3 shares · 5,235 followers View post →
Neal Asher
@nealasher · X

https://t.co/wCXnzSkBPZ

Aug 31, 2023 · 1 like · 13,033 followers View post →

All mentions

FreeFrenchCitizen
@FreeFrenchCiti1 · X

La recherche révèle que le sucre n'est plus la cause principale de la ré... https://t.co/ZYHIh5QFyZ via @YouTube

Jul 24, 2025 · 710 followers View post →
FreeFrenchCitizen
@FreeFrenchCiti1 · X

La recherche révèle que le sucre n'est plus la cause principale de la ré... https://t.co/JKmLVrWy2D via @YouTube

Jul 24, 2025 · 710 followers View post →
MD SAGIR KAZI
@SagirKazi1993 · X

https://t.co/NzULSnVZB3

Mar 3, 2025 · 7 followers View post →
Md Ripon Miah
@MdRipon00779013 · X

রোজায় সহজে ওজন কমানোর উপায় কি? Sabbir Ahmed https://t.co/FD9lqheawx via @YouTube

Mar 15, 2024 · 5 followers View post →
Stephen Poprafsky
@SPoprafsky · X

https://t.co/d2WncwL9Dx

Feb 7, 2024 · 1 followers View post →
أ.د.فهد الخضيري
@DrAlkhodairy · X

Trans Fatty Acid Intake Induces Intestinal Inflammation and Impaired Glucose Tolerance - PMCالدهون المتحولة تدعم التهابات الأمعاء وتدعم مقاومة الأنسولين ، فقللوا منها او اتركوها https://t.co/M4aOzlMIPh

Dec 1, 2023 · 9 likes · 1 share · 1,117,573 followers View post →
ValuableToKnow
@ValuableToKnow · X

"18 Most Inflammatory Foods to Limit Eating - Revised List for 2023" https://t.co/KaOB3Oe3a7

Oct 19, 2023 · 1,711 followers View post →
PreeyaPenny
@PreeyaPenny · X

Sep 22, 2023 · 115 followers View post →
Grey Ghost
@GreyGhost000 · X

18 Most Inflammatory Foods to Limit Eating - Revised List for 2023 https://t.co/KzSq2YewgF via @YouTube THIS GUY IS GREAT..

Sep 19, 2023 · 677 followers View post →
chancechants
@chancechants · X

@KellyOwens9997 @hubermanlab @BioLayne Six year monkey study was one I heard of recently https://t.co/FYwE2hEo2p

Sep 19, 2023 · 503 followers View post →
vegasbling
@vegasbling · X

18 Most Inflammatory Foods to Limit Eating - Revised List for 2023 https://t.co/k4BDaSLend via @YouTube

Sep 18, 2023 · 1,765 followers View post →
Roxana Saez
@CuritadeRana · X

My diet is less than ideal but many of the major problematic key players have been removed over the years. This will put you in a better position to stick with any diet & exercise program you chose for yourself

Sep 16, 2023 · 86 followers View post →
AMERICA'S BEST PATRIOT☄️
@AlisonBoxxer · X

18 Most Inflammatory Foods to Limit Eating - Revised List for 2023 https://t.co/phcDfrdhvE via @YouTube

Sep 15, 2023 · 9,675 followers View post →
Dennis Thompson
@appoco · X

18 Most Inflammatory Foods to Limit Eating - Revised List for 2023 https://t.co/OY4hZohZ74 via @YouTube

Sep 15, 2023 · 20 followers View post →
Truths for Life
@Truthforlife77 · X

18 Most Inflammatory Foods to Limit Eating - Revised List for 2023 https://t.co/yvOB1kx5xW via @YouTube

Sep 14, 2023 · 32 followers View post →
blubber_bones
@blubber_bones · X

18 Most Inflammatory Foods to Limit Eating - Revised List for 2023 https://t.co/xaaoydzWkU via @YouTube

Sep 14, 2023 · 1,079 followers View post →
Ben Taylor
@BenjamminTaylor · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/XMrtLvy6qz via @YouTube

Sep 7, 2023 · 175 followers View post →
Joseph Bellofatto
@JoeBellofatto · X

@AlpacaAurelius https://t.co/7bROBVWrDN

Sep 6, 2023 · 1 like · 634 followers View post →
HorseGirl in Pearls
@SwtCharlemaigne · X

@SentientBlobBob @KenDBerryMD @EliLillyandCo 1. I am not your female dog. 2. are you always so rude to people you don't know, or their background? I am in functional Medicine and write/edit medical content. 3. suggest you listen to this for your arrogant closed minded self might learn something https://t.co/eSTjzhmPhc

Sep 6, 2023 · 5,372 followers View post →
DeBrota Career Consulting
@DebrotaC · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/OR7SaWXntm via @YouTube

Sep 5, 2023 · 4 followers View post →
Just Another Jersey Chick in DuPage
@farmerjaneusa · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/79sB4XQkRM

Sep 5, 2023 · 6,864 followers View post →
Tracy
@xxtracy09xx · X

RT @xxtracy09xx: Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/rP2QCZpwL7 via @YouTube

Sep 5, 2023 · 1 share · 1,179 followers View post →
Tracy
@xxtracy09xx · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/rP2QCZpwL7 via @YouTube

Sep 5, 2023 · 1 like · 1 share · 1,179 followers View post →
Shaun Thunder
@shaunthunder1 · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/95OFjTVmbS via @YouTube

Sep 5, 2023 · 414 followers View post →
Tracy
@xxtracy09xx · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/pNmH9GLGCu via @YouTube

Sep 5, 2023 · 1,179 followers View post →
Dr. Suzana Mantovani
@Tweet_Nutrition · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/tITf1mQMNJ via @YouTube

Sep 4, 2023 · 4,579 followers View post →
Stagon
@Stagon19 · X

@robertlufkinmd There may be more to insulin resistance than we thought ? Study1 https://t.co/oXwELP2EYF Study2 https://t.co/pDqFPlPoGJ

Sep 4, 2023 · 183 followers View post →
lexyacc
@lexyacc10 · X

@NutritionMadeS3 artificial fats are he problem in this report https://t.co/e2edG01ZNf

Sep 4, 2023 · 693 followers View post →
lexyacc
@lexyacc10 · X

@NutritionMadeS3 Artificial fats are the problem https://t.co/e2edG01ZNf

Sep 4, 2023 · 693 followers View post →
Maria Angela Grow
@MariaAngelaGrow · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/Yj6xjEhxXB

Sep 4, 2023 · 1 like · 3,633 followers View post →
Peggy Amaya
@PeggyAmaya36064 · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/B5opKaQG5o via @YouTube

Sep 4, 2023 · 72 followers View post →
Timothy Johnson
@Chrononaut_2045 · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/S3rPULBSxR via @YouTube

Sep 4, 2023 · 67 followers View post →
Patrice Boivin also @patboivin.bsky.social
@PatriceBoivin · X

More evidence that trans fats are bad https://t.co/sqEeeHqtRc heated vegetable oils like in deep frying? @KenDBerryMD

Sep 3, 2023 · 533 followers View post →
Gerry K
@GerryK22141809 · X

RT @GerryK22141809: Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/lflJ2ZEjAL via @YouTube

Sep 3, 2023 · 1 share · 1,166 followers View post →
Gerry K
@GerryK22141809 · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/lflJ2ZEjAL via @YouTube

Sep 3, 2023 · 1 like · 1 share · 1,166 followers View post →
Richard Roberts (Shake N Bake = Decentralize)
@RickyBobby_USA · X

@KenDBerryMD https://t.co/zr6KFIWVgg

Sep 2, 2023 · 1 like · 4,540 followers View post →
Gary T. Sottile
@GPZO · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/WPnPr5aTTG via @YouTube

Sep 2, 2023 · 1,060 followers View post →
Pietro Marchesi
@p_marchesi · X

This study revealed that compared to saturated fatty acid intake, trans fatty acid intake significantly exacerbated metabolic diseases such as diabetes and fatty liver. https://t.co/cLk4huQGhR

Sep 2, 2023 · 1,474 followers View post →
RJ4508
@RBJ508 · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/kxptVePGGu via @YouTube

Aug 31, 2023 · 145 followers View post →
Neal Asher
@nealasher · X

https://t.co/wCXnzSkBPZ

Aug 31, 2023 · 1 like · 13,033 followers View post →
Anna Peck
@AuntieHugs · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/VjvKPZeeSh via @YouTube

Aug 30, 2023 · 1,052 followers View post →
blubber_bones
@blubber_bones · X

Research Finds Sugar is NOT is the #1 Cause of Insulin Resistance Anymore https://t.co/XmVlrfHCJ1 via @YouTube

Aug 30, 2023 · 1,079 followers View post →
theequalizer
@eeequalizerr · X

@iluminatibot https://t.co/vKf8KOKQ87

Jul 20, 2023 · 1 followers View post →
Pati M
@PatiM2 · X

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Jul 18, 2023 · 4,274 followers View post →
blubber_bones
@blubber_bones · X

What Happens to Your Body When You Eat Fast Food Every Day https://t.co/TJtUqW2f7A via @YouTube

Jul 18, 2023 · 1,079 followers View post →
ساره RDN
@sarahrdn8 · X

https://t.co/CiD7Vod3xZ

Jun 26, 2023 · 6 likes · 8,990 followers View post →
JustinAnthony
@JustinA10650720 · X

RT @CristinaDragani: A #diet high in trans fatty acids (chemically altered vegetable oils) significantly increased blood #glucose levels, #…

May 7, 2023 · 4 shares · 507 followers View post →
François Booream
@BooraemFrancois · X

@EthicalSkeptic I tend to think its probably a top predator ie round up, but with cascading ripples .. cleaning products that promise to kill "99% of germs", over use of antibiotics/medication in general. oxidised vegetable oils etc. dont forget trans fats.. https://t.co/vvJ3peJOg8

May 3, 2022 · 13 likes · 1 share · 729 followers View post →
Aris Christodoulou
@ArisChristod · X

RT @SophieGironi: Et si on arrêtait de manger de la

May 3, 2022 · 3 shares · 1,275 followers View post →
Siga
@siga_care · X

RT @SophieGironi: Et si on arrêtait de manger de la

May 3, 2022 · 3 shares · 719 followers View post →
Em_laMalice
@Em_laMalice · X

RT @SophieGironi: Et si on arrêtait de manger de la

Apr 28, 2022 · 3 shares · 25 followers View post →
✨ Sophie Gironi ✨
@SophieGironi · X

Et si on arrêtait de manger de la

Apr 27, 2022 · 3 likes · 3 shares · 5,235 followers View post →
John Greene
@Greene_Thoughts · X

RT @CristinaDragani: A #diet high in trans fatty acids (chemically altered vegetable oils) significantly increased blood #glucose levels, #…

Jun 1, 2021 · 4 shares · 1,673 followers View post →
鳴海 梁
@RyoNarumi1 · X

RT @CristinaDragani: A #diet high in trans fatty acids (chemically altered vegetable oils) significantly increased blood #glucose levels, #…

Jun 1, 2021 · 4 shares · 130 followers View post →
CHSeaton
@COSseaton · X

RT @CristinaDragani: A #diet high in trans fatty acids (chemically altered vegetable oils) significantly increased blood #glucose levels, #…

Jun 1, 2021 · 4 shares · 5,932 followers View post →
Cristina Dragani
@CristinaDragani · X

A #diet high in trans fatty acids (chemically altered vegetable oils) significantly increased blood #glucose levels, #diabetes risk, and fatty liver, in a study in mice. It also changes the gut #microbiome, increasing populations of bad #bacteria. https://t.co/Qt8BqmuVUp https://t.co/K5uryanAuP

Jun 1, 2021 · 13 likes · 4 shares · 10,820 followers View post →
Sáfárné Hatrágyi Henrietta
@HatragyiSafarne · X

#TransFattyAcid Intake Induces #Intestinal #inflammation and Impaired #glucose Tolerance. https://t.co/ENujkHmdc5

May 17, 2021 · 1 like · 490 followers View post →
Symbiosis papers
@Symbiosispapers · X

Trans Fatty Acid Intake Induces Intestinal Inflammation and Impaired Glucose Tolerance https://t.co/snsh5taDrU

May 17, 2021 · 1 like · 1,114 followers View post →
Dr. Stuart Fischer
@TheFitDr · X

Frontiers | Trans fatty acid intake induces intestinal inflammation and impaired glucose tolerance | Immunology https://t.co/FzIH8mP8XN

Apr 15, 2021 · 17,591 followers View post →