July 2021 PMID 34003796

Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection.

Sandra Henein, Cameron Adams, Matthew Bonaparte, Janice M Moser, Alina Munteanu, Ralph Baric, Aravinda M de Silva

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Mentions

Peak: 12 in May 2021

across 3 sources since May 2021

Extended reach

37,544

potential audience

Total likes

Video views

213

Mentions per month

May 2021 – Jul 2021

Where it's discussed

X / Twitter12 posts
News12 articles
YouTube2 videos

AI synopsis

What people are saying

The collection reflects a general acknowledgment of the research, with phrases like 'linked to protection' and references to the publication source indicating recognition of the study's importance. The tone remains mostly factual and reserved, showing moderate interest and engagement, possibly because the topic is technical and specialized, with less emotional or provocative language.

AgreementNeither agree nor disagree

Most discussions appear neutral or mildly supportive, acknowledging the research without strong opinions.

InterestModerate interest

Participants show some curiosity about the significance of neutralizing antibodies, indicated by the moderate interest score.

EngagementNeutral engagement

The posts mainly share the publication's findings or references, with limited in-depth analysis or debate.

ImpactModerate impact

The discussions suggest that the findings are noteworthy but not yet perceived as highly transformative or urgent.

Abstract in brief

The study compares neutralizing antibodies (NAbs) generated by natural dengue infections versus those induced by the Dengvaxia vaccine, highlighting differences in their ability to recognize specific virus epitopes.
Findings suggest that natural infections produce NAbs targeting unique, type-specific epitopes, while the vaccine stimulates cross-reactive NAbs that recognize conserved epitopes across multiple serotypes, which may impact vaccine effectiveness.
The research indicates that in children without prior dengue exposure, the vaccine-induced cross-neutralizing antibodies can neutralize certain serotypes in vitro but do not necessarily protect against infection in vivo, emphasizing that type-specific NAbs might be a better indicator of protection than overall NAb levels.]

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All mentions

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Youtube Microbiology Journal Club · Jul 12, 2021 86 views

WorldDengueDay

@WorldDengueDay · X

RT @mosquito_papers: Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection https://t.co/…

May 19, 2021 · 1 share · 2,406 followers View post →

Jorge Arroba Ditto

@JorgeArrobaD · X

RT @waleman64: Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection - PubMed https://t.…

May 19, 2021 · 3 shares · 508 followers View post →

Rosa María del Angel

@rosamdelangel · X

RT @ArboNews: Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection https://t.co/AIq4N7d…

May 19, 2021 · 4 shares · 1,210 followers View post →

Dr. Gaurav Shrivastava

@gvshrivastava · X

RT @ArboNews: Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection https://t.co/AIq4N7d…

May 19, 2021 · 4 shares · 309 followers View post →

Bloodsucking Parasites

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RT @mosquito_papers: Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection https://t.co/…

May 19, 2021 · 1 share · 5,100 followers View post →

MosquitoPapers

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Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection https://t.co/JjkNkdy2vH

May 19, 2021 · 1 like · 1 share · 2,457 followers View post →

☣️Bryan King☣️

@Bking1789 · X

RT @ArboNews: Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection https://t.co/AIq4N7d…

May 18, 2021 · 4 shares · 219 followers View post →

Bloodsucking Parasites

@bloodSparasites · X

RT @ArboNews: Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection https://t.co/AIq4N7d…

May 18, 2021 · 4 shares · 5,100 followers View post →

CafeConBaileys

@BaileysConCafe · X

RT @waleman64: Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection - PubMed https://t.…

May 18, 2021 · 3 shares · 959 followers View post →

Dr. Juan García G.

@Juanpo86 · X

RT @waleman64: Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection - PubMed https://t.…

May 18, 2021 · 3 shares · 702 followers View post →

Dr. W. Aleman

@waleman64 · X

Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection - PubMed https://t.co/oM2juTSGO9

May 18, 2021 · 7 likes · 3 shares · 13,216 followers View post →

Arbovirus News

@ArboNews · X

Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection https://t.co/AIq4N7d5nR

May 18, 2021 · 5 likes · 4 shares · 5,076 followers View post →

Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Impact of SARS-CoV-2 Vaccines on Immune Response Dynamics

Impact of SARS-CoV-2 Delta Variant on Immunity and Vaccination