PubHawk
Front Nutr May 2021 PMID 34026802

Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes.

Kevin J M Paulussen, Colleen F McKenna, Joseph W Beals, Kenneth R Wilund, Amadeo F Salvador, Nicholas A Burd

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Mentions

68
Peak: 23 in May 2021
across 4 sources since May 2021

Extended reach

6,581,722
potential audience

Total likes

95,391

Video views

4,917,317

Mentions per month

May 2021 – Dec 2025

Where it's discussed

  • X / Twitter48 posts
  • YouTube14 videos
  • News4 articles
  • Facebook2 posts

AI synopsis

What people are saying

Discussions mainly focus on confirming the significance of anabolic resistance, with posts like @Cernovich and @KevinPaulussen emphasizing its impact in various populations, and others like @ScepticalDoctor highlighting practical mitigation strategies such as resistance training. The tone ranges from informational to confirmatory, reflecting a shared understanding of the article's importance and relevance to aging and fitness routines.

AgreementModerate agreement

Most discussions acknowledge the validity and importance of the concepts presented in the publication, with some emphasizing the variability across different populations.

InterestHigh interest

The discussions consistently highlight the relevance of anabolic resistance, especially among aging populations, showing high engagement with the topic.

EngagementModerate engagement

Posts include references to strategies like exercise and nutrition, and some provide summaries or figures, indicating moderate to deep engagement.

ImpactModerate impact

The conversations suggest this research influences clinical and fitness practices, though it's still building awareness across broader audiences.

Abstract in brief

  • Anabolic resistance refers to the reduced ability of muscles to increase protein synthesis in response to stimuli like eating protein or exercising, which can lead to muscle loss and decreased physical performance.
  • The degree of anabolic resistance can vary widely depending on factors such as aging, obesity, and disease, acting like a dimmer switch that can be more or less active in different populations.
  • Increasing physical activity and engaging in targeted exercise are primary strategies to help improve muscle sensitivity to dietary proteins and combat muscle loss across various populations.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Cernovich
@Cernovich · X

Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/zZ1inL7xkU

Dec 14, 2023 · 101 likes · 10 shares · 1,449,628 followers View post →
Dr. Myohead
@DrMyohead · X

Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein effective under most conditions, but not a universal remedy. Nice review from @KevinPaulussen & @Nicholas_Burd https://t.co/8NfiHlyq5S https://t.co/HOkbpv7Bdu

May 5, 2021 · 49 likes · 11 shares · 2,646 followers View post →
Craig A. Goodman
@CraigAGoodman1 · X

Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/Ld01yG8mG0

May 25, 2021 · 18 likes · 2 shares · 3,905 followers View post →
Nicholas Burd
@Nicholas_Burd · X

Brief review discussing that anabolic resistance can look different depending on the population (e.g., aging, obesity, CKD,.....). Nice job, @KevinPaulussen https://t.co/DBX0E3aAsL

May 5, 2021 · 15 likes · 4 shares · 1,025 followers View post →
Dr. Beto CoGa
@BetoCortesGale1 · X

Sarcopenia

Jun 10, 2025 · 12 likes · 3 shares · 2,676 followers View post →
Saúl Sánchez
@SaulNutri · X

Aug 28, 2022 · 9 likes · 107,842 followers View post →

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Dagoberto
@Dagorunner · X

RT @BetoCortesGale1: Sarcopenia

Jun 10, 2025 · 3 shares · 550 followers View post →
Childre González
@MilenGafaro · X

RT @BetoCortesGale1: Sarcopenia

Jun 10, 2025 · 3 shares · 2,663 followers View post →
Fabio Valencia
@MARATON10 · X

RT @BetoCortesGale1: Sarcopenia

Jun 10, 2025 · 3 shares · 1,007 followers View post →
Dr. Beto CoGa
@BetoCortesGale1 · X

Sarcopenia

Jun 10, 2025 · 12 likes · 3 shares · 2,676 followers View post →
Gabriel Pérez
@gperez441 · X

RT @a_fisiolog57853: https://t.co/tOafrxo35t

Mar 28, 2024 · 1 share · 285 followers View post →
Walter Suárez Carmona
@a_fisiolog57853 · X

https://t.co/tOafrxo35t

Mar 26, 2024 · 3 likes · 1 share · 3,915 followers View post →
ZOLO
@zoljar6al · X

RT @Cernovich: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/zZ1inL7xkU

Dec 15, 2023 · 10 shares · 105 followers View post →
black dragon 25
@blackdragon253 · X

RT @Cernovich: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/zZ1inL7xkU

Dec 15, 2023 · 10 shares · 881 followers View post →
The Variant
@mtnbiker666 · X

RT @Cernovich: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/zZ1inL7xkU

Dec 14, 2023 · 10 shares · 93 followers View post →
Sam
@Nicotinenation · X

RT @Cernovich: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/zZ1inL7xkU

Dec 14, 2023 · 10 shares · 472 followers View post →
saltyseal1
@saltyseal1 · X

RT @Cernovich: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/zZ1inL7xkU

Dec 14, 2023 · 10 shares · 92 followers View post →
David Leung
@dleungnyc · X

RT @Cernovich: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/zZ1inL7xkU

Dec 14, 2023 · 10 shares · 1,828 followers View post →
Cernovich
@Cernovich · X

Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/zZ1inL7xkU

Dec 14, 2023 · 101 likes · 10 shares · 1,449,628 followers View post →
Saúl Sánchez
@SaulNutri · X

Aug 28, 2022 · 9 likes · 107,842 followers View post →
Café negro y sin azúcar ☕
@FannyMuS · X

RT @IberianCitizen: No, no es la edad. Son los hábitos. #Resistencia #Anabólica https://t.co/CIpdgjptSQ https://t.co/tEYQEbjFyt

May 15, 2022 · 1 share · 356 followers View post →
IberianCitizen
@IberianCitizen · X

No, no es la edad. Son los hábitos. #Resistencia #Anabólica https://t.co/CIpdgjptSQ https://t.co/tEYQEbjFyt

May 14, 2022 · 8 likes · 1 share · 12,932 followers View post →
Marcus Wolford
@mvmntcoach · X

@Nutradvance Anabolic Resistance - https://t.co/G1Xf0PHxNl Stu’s paper for the RDA at 1.2g/kg - https://t.co/3aJG2GiLsD

Mar 22, 2022 · 1 like · 2,436 followers View post →
Marcus Wolford
@mvmntcoach · X

@ScepticalDoctor Well, it's all mitigation not prevention. Our best chance of mitigation of many negative effects of aging is ⬆️protein + ⬆️resistance training. Much of this is due to decreased anabolic signaling as we age or what is termed "Anabolic Resistance". https://t.co/G1Xf0PZ9bV

Feb 22, 2022 · 1 like · 2,436 followers View post →
Marcus Wolford
@mvmntcoach · X

For most us, our muscle mass remains mostly unchanged until we reach older ages (50+). Much of this is b/c of inactivity, but its also b/c of something called "Anabolic Resistance" - reduced MPS response to both protein & exercise leading to muscle loss. https://t.co/G1Xf0PHxNl

Jan 15, 2022 · 1 like · 2,436 followers View post →
Eve Beavers
@espacetimeCO · X

RT @_PaulMorgan: Very nice summary from @KevinPaulussen @Nicholas_Burd et al “Anabolic Resistance of Muscle Protein Turnover Comes in Vario…

Nov 2, 2021 · 2 shares · 898 followers View post →
Hec
@Muscles_n_Mitos · X

RT @_PaulMorgan:

Nov 2, 2021 · 1 share · 63 followers View post →
Joachim Nielsen
@JoachimNielsen6 · X

RT @_PaulMorgan: Very nice summary from @KevinPaulussen @Nicholas_Burd et al “Anabolic Resistance of Muscle Protein Turnover Comes in Vario…

Nov 1, 2021 · 2 shares · 1,299 followers View post →
Paul Morgan
@_PaulMorgan · X

Very nice summary from @KevinPaulussen @Nicholas_Burd et al “Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes” … a figure for the teaching slides

Nov 1, 2021 · 4 likes · 2 shares · 1,320 followers View post →
Paul Morgan
@_PaulMorgan · X

Nov 1, 2021 · 1 share · 1,320 followers View post →
Karageorgos
@Karageorgos15 · X

RT @DrMyohead: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein ef…

Jun 18, 2021 · 11 shares · 611 followers View post →
Hec
@Muscles_n_Mitos · X

RT @CraigAGoodman1: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/Ld01yG8mG0

May 25, 2021 · 2 shares · 63 followers View post →
Craig A. Goodman
@CraigAGoodman1 · X

Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes https://t.co/Ld01yG8mG0

May 25, 2021 · 18 likes · 2 shares · 3,905 followers View post →
Toppform Oslo
@Toppform_gym · X

RT @FrontNutrition: New Research: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes: Anabolic resistance is…

May 8, 2021 · 3 shares · 244 followers View post →
Kevin Paulussen
@KevinPaulussen · X

RT @Nicholas_Burd: Brief review discussing that anabolic resistance can look different depending on the population (e.g., aging, obesity, C…

May 8, 2021 · 4 shares · 67 followers View post →
Susannah Scaroni
@KenyanScaroni · X

RT @Nicholas_Burd: Brief review discussing that anabolic resistance can look different depending on the population (e.g., aging, obesity, C…

May 6, 2021 · 4 shares · 1,537 followers View post →
Joss Port
@Joss_Port · X

RT @DrMyohead: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein ef…

May 6, 2021 · 11 shares · 63 followers View post →
javierbutra
@javierbutra · X

RT @nick_krontiris: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes (open access) https://t.co/U4sXxk0BpC…

May 6, 2021 · 2 shares · 14,339 followers View post →
Vince
@Vince_Mrgn · X

RT @nick_krontiris: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes (open access) https://t.co/U4sXxk0BpC…

May 6, 2021 · 2 shares · 126 followers View post →
Pediatrics & Therapeutics
@TherapeuticsAnd · X

RT @DrMyohead: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein ef…

May 6, 2021 · 11 shares · 37 followers View post →
Fundación Iberoamericana de Nutrición
@FinutOrg · X

RT @FrontNutrition: New Research: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes: Anabolic resistance is…

May 6, 2021 · 3 shares · 4,047 followers View post →
Ignacio Hernando Valle
@nachoafysalud · X

RT @DrMyohead: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein ef…

May 6, 2021 · 11 shares · 5,831 followers View post →
Nick Krontiris
@nick_krontiris · X

Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes (open access) https://t.co/U4sXxk0BpC #exercise #fitness #fit #FitFam #FitLife #FitnessAddict #Workout #TrainHard #GymLife #GymTime #muscle #strength #lift #GetStrong #hypertrophy #gainz #gains

May 6, 2021 · 5 likes · 2 shares · 19,019 followers View post →
Gavin Connolly, PhD
@GavinConnolly1o · X

RT @DrMyohead: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein ef…

May 5, 2021 · 11 shares · 365 followers View post →
Frontiers - Nutrition
@FrontNutrition · X

New Research: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes: Anabolic resistance is defined by a blunted stimulation of muscle protein synthesis rates (MPS) to common anabolic stimuli in skeletal muscle… https://t.co/QQyo9ntLP2 #Nutrition

May 5, 2021 · 4 likes · 3 shares · 3,900 followers View post →
Argón
@metilargon · X

RT @DrMyohead: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein ef…

May 5, 2021 · 11 shares · 356 followers View post →
Jim Edwards
@Movement4Ages · X

RT @DrMyohead: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein ef…

May 5, 2021 · 11 shares · 135 followers View post →
Milan Betz
@MilanWBetz · X

RT @DrMyohead: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein ef…

May 5, 2021 · 11 shares · 218 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

RT @DrMyohead: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein ef…

May 5, 2021 · 11 shares · 6,726 followers View post →
Alex Olmos, PhD
@olmosalex65 · X

RT @DrMyohead: Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein ef…

May 5, 2021 · 11 shares · 105 followers View post →
zanzup
@ZanZupancic18 · X

RT @Nicholas_Burd: Brief review discussing that anabolic resistance can look different depending on the population (e.g., aging, obesity, C…

May 5, 2021 · 4 shares · 40 followers View post →
Dr. Myohead
@DrMyohead · X

Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes Move more and eat above RDA for protein effective under most conditions, but not a universal remedy. Nice review from @KevinPaulussen & @Nicholas_Burd https://t.co/8NfiHlyq5S https://t.co/HOkbpv7Bdu

May 5, 2021 · 49 likes · 11 shares · 2,646 followers View post →
Dr Richard Mackenzie
@mackenzie_dr · X

RT @Nicholas_Burd: Brief review discussing that anabolic resistance can look different depending on the population (e.g., aging, obesity, C…

May 5, 2021 · 4 shares · 963 followers View post →
Nicholas Burd
@Nicholas_Burd · X

Brief review discussing that anabolic resistance can look different depending on the population (e.g., aging, obesity, CKD,.....). Nice job, @KevinPaulussen https://t.co/DBX0E3aAsL

May 5, 2021 · 15 likes · 4 shares · 1,025 followers View post →