The discussions predominantly reflect strong interest and support, evident through mentions of the study’s detailed immune and fibrosis profiling and potential for treatment strategies, such as targeting the JAK-STAT pathway. Words like 'latest research' and 'reveals' suggest a tone of scientific curiosity and optimism, while references to treatment implications indicate recognition of significant practical impact.
AgreementModerate agreement
Most discussions acknowledge and support the importance of the study, highlighting its scientific contributions.
InterestHigh interest
The majority find the research highly relevant, especially those focused on hair loss and autoimmune mechanisms.
EngagementModerate engagement
Participants show moderate engagement, discussing methodologies and potential implications without in-depth critique.
ImpactModerate impact
The findings are viewed as potentially impactful, informing future treatments and understanding of FFA.
Abstract in brief
The study found that frontal fibrosing alopecia (FFA) is primarily an inflammatory scalp condition involving immune system dysregulation, particularly with Th1 and JAK-STAT pathways, leading to scarring and fibrosis without affecting the rest of the body.
Researchers identified specific genes and biomarkers related to immune activation and fibrosis in scalp tissue, such as CXCL9, CXCL10, FOXP3, and TGFB1, which correlate with disease severity.
The findings suggest that targeting the JAK-STAT pathway could be a potential treatment approach for FFA, as the disease shows signs of being reversible through inhibition of this immune signaling pathway.]
Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement https://t.co/eTbCXk6jHe https://t.co/hsmWhHSxOB
Mar 4, 2022 · 7 likes · 2 shares · 18,616 followersView post →
DD
Dr. Jeff Donovan,
@DonovanMedical · X
This week’s Evidence Based Hair podcast addresses the latest research in scarring alopecia from the past 1-2 months. I’ll be reviewing 3 studies in FFA, 2 in LPP, 2 in CCCA and 1 in FD. https://t.co/60PoiNK9a2 #scarringalopecia
Mar 21, 2022 · 3 likes · 1 share · 3,482 followersView post →
PB
Public Health Bulletin
@BulletinPublic · X
Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. https://t.co/MxojDXhrKH
This video reviews the most influential hair research studies published in 2022, emphasizing immune system involvement and fibrosis in scalp conditions like frontal fibrosing alopecia, highlighting potential therapeutic…
This episode discusses research showing frontal fibrosing alopecia is an inflammatory scalp condition involving immune dysregulation, especially in Th1 and JAK-STAT pathways, leading to scarring but no systemic effects…
This week’s Evidence Based Hair podcast addresses the latest research in scarring alopecia from the past 1-2 months. I’ll be reviewing 3 studies in FFA, 2 in LPP, 2 in CCCA and 1 in FD. https://t.co/60PoiNK9a2 #scarringalopecia
Mar 21, 2022 · 3 likes · 1 share · 3,482 followersView post →
LA
Lt Col MD David Perez-Meza FISHRS ABHRS
@drdaviperezmeza · X
RT @JAADjournals: Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic…
RT @JAADjournals: Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic…
Mar 4, 2022 · 2 shares · 35,131 followersView post →
JJ
JAAD Journals
@JAADjournals · X
Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement https://t.co/eTbCXk6jHe https://t.co/hsmWhHSxOB
Mar 4, 2022 · 7 likes · 2 shares · 18,616 followersView post →
JR
José R. Ribeiro
@JoseRodRibeiro · X
RT @RevPortPneumol: Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemi…
Jun 12, 2021 · 1 share · 9,295 followersView post →
PB
Public Health Bulletin
@BulletinPublic · X
Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. https://t.co/MxojDXhrKH
Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement https://t.co/m203KEmbKl
2021-Clinical and Pathologic Correlation of Cutaneous COVID-19 ...
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... 10.1016/j.jaad.2021.09.002. Department of Medicine, Massachusetts General ... //doi.org/10.1016/j.det.2021.05.016 445-447. 5. Sadoff J, Le Gars M ...