The digital discussions reflect strong interest and acknowledgment of the research's potential, with phrases like 'new research might have found a way to bust biofilm bacteria' and references to hydrogen sulfide's role in bacterial survival, which underscore curiosity and perceived significance of the findings. Words such as 'promising' and 'enhances the deadly effects' convey optimism, but the tone remains cautious, indicating respect for the scientific advancement without overhyping it.
AgreementModerate agreement
Most discussions agree on the significance of targeting bacterial hydrogen sulfide to combat antibiotic resistance, citing the potential for improving antimicrobial effectiveness.
InterestHigh interest
Posts demonstrate high curiosity, referencing detailed findings like hydrogen sulfide's role in bacterial defenses and the development of inhibitors.
EngagementModerate engagement
The discourse involves some depth, with mentions of the research process, mechanisms, and potential applications, but stops short of critical analysis.
ImpactModerate impact
The discussions recognize the research's importance, highlighting its promise for advancing antibiotic strategies, though they do not depict it as a guaranteed breakthrough.
Abstract in brief
The study focuses on combating antibiotic resistance by targeting bacterial hydrogen sulfide (HS) production, which helps bacteria defend against antibiotics.
Researchers identified cystathionine lyase CSE as the main enzyme producing HS in two major pathogens and developed small molecules to inhibit this enzyme.
These CSE inhibitors enhance the effectiveness of antibiotics, reduce bacterial biofilm formation and tolerance, and decrease persister bacteria, making them promising as adjuvants for antibiotic therapy.]
Targeting hydrogen sulfide production in bacteria enhances the deadly effects of antimicrobials on drug-resistant pathogens, @nyulangone researchers report in @ScienceMagazine. The findings offer promise for developing highly effective #antibiotics https://t.co/c9044btmIA
Jun 10, 2021 · 1 like · 1,963 followersView post →
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Rene Sugar
@renesugar · X
Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance and tolerance
https://t.co/9xdta829ia
Researchers Discover Critical Role of Hydrogen Sulfide in Ability of Bacteria to Survive Antibiotics
https://t.co/QG89HPj8wg
"By releasing hydrogen sulfide, bacteria avoid being killed by antibiotics."
https://t.co/9xdta8jcka
@cshperspectives Kostya isn't 70 yet, but over 60 and works at the bench still, and still has 1st author papers in Science.
Shatalin K, et al. Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance and tolerance. Science. 2021. doi: 10.1126/science.abd8377. PMID: 34112687.
This video explores how inhibiting bacterial hydrogen sulfide production can combat antibiotic resistance. Researchers identified key enzymes and developed inhibitors that improve antibiotic efficacy and reduce…
This edition of weekly scientific reports covers recent developments in COVID-19 research, including classroom safety risks during the pandemic, herd immunity in communities, and mask efficacy in virus transmission…
@cshperspectives Kostya isn't 70 yet, but over 60 and works at the bench still, and still has 1st author papers in Science.
Shatalin K, et al. Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance and tolerance. Science. 2021. doi: 10.1126/science.abd8377. PMID: 34112687.
Researchers Discover Critical Role of Hydrogen Sulfide in Ability of Bacteria to Survive Antibiotics
https://t.co/QG89HPj8wg
"By releasing hydrogen sulfide, bacteria avoid being killed by antibiotics."
https://t.co/9xdta8jcka
Targeting hydrogen sulfide production in bacteria enhances the deadly effects of antimicrobials on drug-resistant pathogens, @nyulangone researchers report in @ScienceMagazine. The findings offer promise for developing highly effective #antibiotics https://t.co/c9044btmIA
Jun 10, 2021 · 1 like · 1,963 followersView post →
N
Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance ...
News
Science. 11 Jun 2021. Vol 372, Issue 6547. pp. 1169-1175. DOI: 10.1126/science.abd8377 · PREVIOUS ARTICLE. Time-resolved structured illumination microscopy ...