November 2021 PMID 34125597

Reinvestigating the Coughing Rat Model of Pertussis To Understand Pathogenesis.

Jesse M Hall, Jason Kang, Sophia M Kenney, Ting Y Wong, Graham J Bitzer, Claire O Kelly, Caleb A Kisamore, Dylan T Boehm, Megan A DeJong, M Allison Wolf, Emel Sen-Kilic, Alexander M Horspool, Justin R Bevere, Mariette Barbier, F Heath Damron

Mentions

3
Peak: 2 in Jul 2021
across 2 sources since Jun 2021

Extended reach

320
potential audience

Total likes

9

Video views

213

Mentions per month

Jun 2021 – Jul 2021

Where it's discussed

  • YouTube2 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

The discussions reflect a general interest in the study, with some posts highlighting the importance of understanding different bacterial strains and their effects, indicated by phrases like 'reinvestigating' and 'better understanding.' The tone remains neutral to mildly positive, emphasizing the relevance of the research without extensive critique or debate.

AgreementModerate agreement

Most discussions recognize the importance of reexamining the coughing rat model to better understand pertussis, showing a moderate level of agreement with the publication's focus.

InterestModerate interest

The discussions display some curiosity about the new study, but do not delve deeply into technical details or implications.

EngagementNeutral engagement

Participants mostly comment casually, with limited in-depth analysis or critical evaluation of the research methods or findings.

ImpactModerate impact

The overall tone suggests that the research is considered somewhat impactful, potentially advancing understanding or future vaccine development, but without strong consensus on immediate significance.

Abstract in brief

  • The study reexamines the coughing rat model of pertussis to better understand how different strains of the bacteria, like Tohama 1 and D420, cause disease, especially since current vaccines are less effective and new strains are emerging.
  • When rats are infected with these strains, they show symptoms such as coughing, lung inflammation, and immune responses, with D420 causing more prolonged coughing and higher antibody production than Tohama 1.
  • Overall, the coughing rat model helps researchers compare how different pertussis strains affect disease symptoms, which is useful for improving vaccines and understanding the disease better.]

Top posts

Most liked on X and Bluesky
Pertussis Papers
@PertussisPapers · X

New paper! Re-investigating the coughing rat model of pertussis to understand Bordetella pertussis pathogenesis https://t.co/WmwNYgI6nw https://t.co/9ioKJRY33S

Jun 15, 2021 · 2 likes · 108 followers View post →

All mentions

Pertussis Papers
@PertussisPapers · X

New paper! Re-investigating the coughing rat model of pertussis to understand Bordetella pertussis pathogenesis https://t.co/WmwNYgI6nw https://t.co/9ioKJRY33S

Jun 15, 2021 · 2 likes · 108 followers View post →