Hum Brain Mapp October 2021 PMID 34132437

A comprehensive score reflecting memory-related fMRI activations and deactivations as potential biomarker for neurocognitive aging.

Joram Soch, Anni Richter, Hartmut Schütze, Jasmin M Kizilirmak, Anne Assmann, Gusalija Behnisch, Hannah Feldhoff, Larissa Fischer, Julius Heil, Lea Knopf, Christian Merkel, Matthias Raschick, Clara-Johanna Schietke, Annika Schult, Constanze I Seidenbecher

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Mentions

Peak: 5 in Jan 2021

across 2 sources since Jan 2021

Extended reach

207,932

potential audience

Total likes

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Mentions per month

Jan 2021 – Apr 2025

Where it's discussed

X / Twitter7 posts
YouTube1 videos

AI synopsis

What people are saying

Discussions demonstrate a positive reception with phrases like 'new biomarker' and 'potential for neurocognitive aging,' showing recognition of the significance of the research. The tone emphasizes curiosity and respect for the methodology, but specific debates or detailed critiques are limited, reflecting moderate engagement and impact.

AgreementModerate agreement

Most discussions express support or recognition of the research's importance, suggesting general agreement with its potential significance.

InterestHigh interest

Several posts highlight curiosity and enthusiasm about the novel biomarkers and their applications, indicating high interest.

EngagementModerate engagement

There are references to the methodology and implications, such as mentions of 'quantifying successful aging' and specific scores, showing moderate engagement.

ImpactModerate impact

While some posts hint at the potential for these biomarkers to influence future research and clinical practice, the overall perception of immediate impact remains moderate.

Abstract in brief

Older adults, especially those at risk for dementia, show declines in episodic memory linked to changes in brain activity that can be detected using fMRI.
A new imaging biomarker called FADE-SAME has been developed to assess memory-related brain activity by evaluating both activations and deactivations during memory tasks, improving upon the original FADE score.
In a study comparing young and older adults, both FADE and FADE-SAME scores showed significant age-related differences and correlated with memory performance, suggesting these scores could serve as valuable biomarkers for assessing neurocognitive aging.

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All mentions

Neurocognitive Aging Biomarker Using Memory fMRI Activations and Deactivations

This study introduces FADE-SAME, a biomarker assessing memory-related brain activity by evaluating fMRI activations and deactivations, distinguishing young and older adults, and correlating with memory performance.

Joram Soch · Apr 3, 2025 17 views

UCL Discovery

@ucl_discovery · X

Open Access UCL Research: A comprehensive score reflecting memory-related fMRI activations and deactivations as potential biomarker for neurocognitive aging https://t.co/mQ5JKheCs6

Apr 8, 2022 · 2,521 followers View post →

UCL Discovery

@ucl_discovery · X

Open Access UCL Research: A comprehensive score reflecting memory-related fMRI activations and deactivations as potential biomarker for neurocognitive aging - UCL Discovery https://t.co/6SbyRlm3UH

Nov 16, 2021 · 2,521 followers View post →

Open Neuroscience

@openneurosci · X

RT @JoramSoch: New @biorxiv_neursci preprint with @SchottBjorn et al. on quantifying successful aging in memory: "A comprehensive score ref…

Jan 19, 2021 · 1 share · 2,371 followers View post →

Joram Soch

@JoramSoch · X

Jan 19, 2021 · 1 like · 1 share · 486 followers View post →

Open Neuroscience

@openneurosci · X

RT @biorxiv_neursci: A comprehensive score reflecting memory-related fMRI activations and deactivations as potential biomarker for neurocog…

Jan 18, 2021 · 1 share · 2,371 followers View post →

bioRxiv Neuroscience

@biorxiv_neursci · X

A comprehensive score reflecting memory-related fMRI activations and deactivations as potential biomarker for neurocognitive aging https://t.co/czY0S6bRdx #biorxiv_neursci

Jan 18, 2021 · 3 likes · 1 share · 60,093 followers View post →

bioRxiv

@biorxivpreprint · X

A comprehensive score reflecting memory-related fMRI activations and deactivations as potential biomarker for neurocognitive aging https://t.co/IRRiiV29Eo #bioRxiv

Jan 18, 2021 · 137,545 followers View post →