July 2021 PMID 34138966

Phenolic compounds disrupt spike-mediated receptor-binding and entry of SARS-CoV-2 pseudo-virions.

Anna Goc, Waldemar Sumera, Matthias Rath, Aleksandra Niedzwiecki

Mentions

11
Peak: 4 in Oct 2021
across 3 sources since Jun 2021

Extended reach

23,728
potential audience

Total likes

428

Video views

12,243

Mentions per month

Jun 2021 – Oct 2022

Where it's discussed

  • X / Twitter7 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The discussions highlight excitement over phenolic compounds like curcumin and theaflavin as potential antiviral agents, with phrases such as 'disrupts' and 'decreases activity' emphasizing their promising effects. The tone remains positive and curious, reflecting interest in both the scientific and therapeutic implications of the research.

AgreementModerate agreement

Most discussions acknowledge the positive potential of phenolic compounds in disrupting SARS-CoV-2 entry, reflecting general agreement with the publication's findings.

InterestHigh interest

The posts show strong enthusiasm for natural compounds like curcumin and theaflavin, indicating high curiosity about their antiviral properties.

EngagementModerate engagement

Participants reference specific compounds and the research process, suggesting moderate to deep engagement with the scientific content.

ImpactModerate impact

The discussions recognize the importance of these findings as promising leads for COVID-19 treatment development, though they remain optimistic rather than conclusive.

Abstract in brief

  • The study found that certain phenolic compounds, especially theaflavin-3,3'-digallate, curcumin, and brazilin, can block the SARS-CoV-2 virus from attaching to human cells by binding to the spike protein or the ACE2 receptor.
  • These compounds not only prevent viral entry but also decrease the activity of enzymes like transmembrane serine protease 2 and cathepsin L, which are crucial for the virus to infect cells.
  • Overall, these polyphenols show multiple ways of fighting the virus, making them promising candidates for further research and potential treatments.]

Top posts

Most liked on X and Bluesky
Abazar Habibinia, MD
@AbazarMd · X

The Power of Phytonutrients: As per a study published by Dr. Rath Research Institute in the USA, #Curcumin disrupts and decreases the activity of ACE2 & TMPRSS2―the two groups of receptors & binding sites of the spike protein of SARS-CoV-2 for an entry. https://t.co/ZA5tIMWdLU

Oct 13, 2021 · 6 likes · 3 shares · 827 followers View post →
Debbie
@MsDianaFrances · X

RT @AbazarMd: The Power of Phytonutrients: As per a study published by Dr. Rath Research Institute in the USA, #Curcumin disrupts and decre…

Oct 14, 2021 · 3 shares · 4,890 followers View post →
Pixie Warrior
@PixieWarrior22 · X

RT @AbazarMd: The Power of Phytonutrients: As per a study published by Dr. Rath Research Institute in the USA, #Curcumin disrupts and decre…

Oct 16, 2021 · 3 shares · 2,259 followers View post →
Francesca Salvati
@Frances47065366 · X

https://t.co/f9wgx42xFj

Aug 21, 2021 · 1 share · 1,726 followers View post →
One Health, India
@One_Health_In · X

Scientists demonstrated the efficacy of specific polyphenols against #SARSCoV2 and their prospects for further scientific and clinical investigations. Read more @PLOSONE https://t.co/sABGkHGVg0

Jun 24, 2021 · 1,028 followers View post →
Tony N
@TonyN47243342 · X

@organichemusic - Theaflavin Standardized Extract https://t.co/zpuRRN1YFx https://t.co/i7XxMbKhei https://t.co/N4FMbk523N https://t.co/gbynUqBe56 https://t.co/fFluTmrxSB https://t.co/hAURMDKJYe https://t.co/dMVyFvDqXE https://t.co/sKDrtCmqQi https://t.co/4gh5Sybzq5 https://t.co/2ONDB9VdjF

Oct 15, 2022 · 550 followers View post →

All mentions

Tony N
@TonyN47243342 · X

@organichemusic - Theaflavin Standardized Extract https://t.co/zpuRRN1YFx https://t.co/i7XxMbKhei https://t.co/N4FMbk523N https://t.co/gbynUqBe56 https://t.co/fFluTmrxSB https://t.co/hAURMDKJYe https://t.co/dMVyFvDqXE https://t.co/sKDrtCmqQi https://t.co/4gh5Sybzq5 https://t.co/2ONDB9VdjF

Oct 15, 2022 · 550 followers View post →
Simba
@Simbaosho · X

RT @AbazarMd: The Power of Phytonutrients: As per a study published by Dr. Rath Research Institute in the USA, #Curcumin disrupts and decre…

Oct 22, 2021 · 3 shares · 180 followers View post →
Pixie Warrior
@PixieWarrior22 · X

RT @AbazarMd: The Power of Phytonutrients: As per a study published by Dr. Rath Research Institute in the USA, #Curcumin disrupts and decre…

Oct 16, 2021 · 3 shares · 2,259 followers View post →
Debbie
@MsDianaFrances · X

RT @AbazarMd: The Power of Phytonutrients: As per a study published by Dr. Rath Research Institute in the USA, #Curcumin disrupts and decre…

Oct 14, 2021 · 3 shares · 4,890 followers View post →
Abazar Habibinia, MD
@AbazarMd · X

The Power of Phytonutrients: As per a study published by Dr. Rath Research Institute in the USA, #Curcumin disrupts and decreases the activity of ACE2 & TMPRSS2―the two groups of receptors & binding sites of the spike protein of SARS-CoV-2 for an entry. https://t.co/ZA5tIMWdLU

Oct 13, 2021 · 6 likes · 3 shares · 827 followers View post →
Francesca Salvati
@Frances47065366 · X

https://t.co/f9wgx42xFj

Aug 21, 2021 · 1 share · 1,726 followers View post →
One Health, India
@One_Health_In · X

Scientists demonstrated the efficacy of specific polyphenols against #SARSCoV2 and their prospects for further scientific and clinical investigations. Read more @PLOSONE https://t.co/sABGkHGVg0

Jun 24, 2021 · 1,028 followers View post →