Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechanoporation to bring intracellular delivery to the next level. Great job, Byeongju Joo! https://t.co/CDxXSrWVc9
Highly Efficient Transfection of Human Primary T Lymphocytes Using Droplet-Enabled Mechanoporation.
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Jun 2021 – Aug 2021Where it's discussed
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X / Twitter24 posts
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YouTube3 videos
AI synopsis
What people are saying
Discussions underscore the novelty of droplet microfluidics combined with mechanoporation, with many posts describing the method as a 'game changer' for cell therapies. The tone is enthusiastic, with phrases like 'excited to share' and mentions of improved efficiency and scalability indicating strong interest and perceived high impact, although engagement remains somewhat focused on overviews rather than deep technical analysis.
Most discussions express positive support and enthusiasm for the research, highlighting its innovation and potential benefits.
Posts show high interest, emphasizing new methods and technological advances in cell transfection.
Some comments discuss the methodology and implications, indicating a moderate level of detailed engagement.
Several posts suggest this research could significantly influence future cellular engineering practices, though some focus on its potential rather than definitive impacts.
Abstract in brief
- This study introduces a new method for efficiently delivering genetic material into human primary T cells using droplet microfluidics combined with cell mechanoporation, which mechanically permeabilizes cell membranes as cells pass through narrow channels.
- The approach reduces the amount of cargo needed, minimizes clogging issues, maintains high cell viability, and achieves better delivery efficiency compared to traditional techniques like viral vectors and electroporation.
- Overall, this droplet-enabled mechanoporation method offers a scalable, cost-effective, and less cytotoxic way to modify cells, with potential applications in cell therapy and genetic engineering.
Top posts
Most liked on X and Blueskynew #ACSNano journal cover! #MyACSCover @ACS4Authors https://t.co/UDCtBA7U0Z https://t.co/0PuX1pOFrk
Transfection/electroporation are the current standards for modifying/loading #immune cells for #whole #cell therapy. Read in @acsnano how @ac467 et al new technique of #droplet-enabled #mechanoporation has high cargo #delivery and #scalability! https://t.co/MmhIQFj3He
RT @ac467: new #ACSNano journal cover! #MyACSCover @ACS4Authors https://t.co/UDCtBA7U0Z https://t.co/0PuX1pOFrk
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
All mentions
Efficient Genetic Delivery Using Droplet-Enabled Mechanoporation
This study introduces a new method for efficiently delivering genetic material into human primary T cells using droplet microfluidics combined with cell mechanoporation, which mechanically permeabilizes cell membranes…
Droplet-Enabled Mechanoporation for Efficient T Cell Transfection
This video showcases high-speed imaging of droplet microfluidics used in mechanoporation to deliver genetic material into human T cells efficiently, reducing cargo use and maintaining cell viability, offering a…
Innovative Microfluidic Technique Enhances T Cell Transfection Efficiency
This study introduces a new droplet microfluidics method combined with cell mechanoporation to efficiently deliver genetic material into human primary T cells, reducing cargo use, improving viability, and offering…
RT @ac467: new #ACSNano journal cover! #MyACSCover @ACS4Authors https://t.co/UDCtBA7U0Z https://t.co/0PuX1pOFrk
RT @ac467: new #ACSNano journal cover! #MyACSCover @ACS4Authors https://t.co/UDCtBA7U0Z https://t.co/0PuX1pOFrk
RT @ac467: new #ACSNano journal cover! #MyACSCover @ACS4Authors https://t.co/UDCtBA7U0Z https://t.co/0PuX1pOFrk
new #ACSNano journal cover! #MyACSCover @ACS4Authors https://t.co/UDCtBA7U0Z https://t.co/0PuX1pOFrk
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @BioconjChem: Transfection/electroporation are the current standards for modifying/loading #immune cells for #whole #cell therapy. Read…
RT @BioconjChem: Transfection/electroporation are the current standards for modifying/loading #immune cells for #whole #cell therapy. Read…
RT @BioconjChem: Transfection/electroporation are the current standards for modifying/loading #immune cells for #whole #cell therapy. Read…
Transfection/electroporation are the current standards for modifying/loading #immune cells for #whole #cell therapy. Read in @acsnano how @ac467 et al new technique of #droplet-enabled #mechanoporation has high cargo #delivery and #scalability! https://t.co/MmhIQFj3He
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
RT @ac467: Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechan…
Excited to share our new work published in @acsnano! We demonstrated how droplet microfluidics can be leveraged with cell mechanoporation to bring intracellular delivery to the next level. Great job, Byeongju Joo! https://t.co/CDxXSrWVc9
[ASAP] Highly Efficient Transfection of Human Primary T Lymphocytes Using Droplet-Enabled Mechanoporation https://t.co/ixCEM3QI1F