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The discussions predominantly express strong agreement and high interest through phrases such as 'big implications', 'ready for prime time', and 'hopeful', emphasizing the potential transformative impact. Engagement is shown by technical references and questions about clinical applications, reflecting deep consideration of the study's significance.
Most discussions acknowledge the validity and promising nature of the study, with some explicitly stating it shows high potential for early detection.
Posts exhibit strong interest, highlighting the relevance for cancer screening, early detection, and clinical implications.
Participants engage by referencing technical details, potential clinical impact, and asking questions about applications, indicating active involvement.
Many posts suggest that this research could significantly influence future cancer diagnostics and screening methods, with phrases like 'big implications' and 'ready for prime time'.
Early detection could improve cure rates, mainly in cancers without screening modalities.
This just published. Ready for prime time? Big implications if so. Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/SUDXGIc9Nm
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set @EricKleinMD @CleClinicMD @ClevelandClinic @OncoAlert #CleClinicCancer @caseccc https://t.co/PpgxhZmjwT
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set - Annals of Oncology https://t.co/8Dwl7Ooz1Z
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set - Annals of Oncology @Annals_Oncology @EricKleinMD @PCF_Science https://t.co/zQT1mn8zpq
#cancer #blood test - #genomics #precisionmedicine Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set - Annals of #Oncology https://t.co/DDbCTcssQ8
Despite advances in cancer care, gaps remain. Dr. Josh Ofman explains how GRAIL's Galleri test detects over 50 cancer types early, before symptoms, potentially improving outcomes and complementing standard screening…
We routinely screen for just three cancers in the UK but more than 4 in 5 cancer deaths are caused by cancers without screening. Sir Harpal Kumar explains how the Galleri multi-cancer early detection test detects over…
I wonder if this blood-based test (or other similar tests) can be studied in patients with cancer predisposition (e.g., hereditary cancer syndromes) to help with early detection. https://t.co/FfLD4hQIKF
New article: Re: Sabrina H. Rossi, Grant D. Stewart. Re: Clinical Validation of a Targeted Methylation-based Multi-cancer Early Detection Test Using an Independent Validation Set. Eur Urol. In press. https://t.co/mivZLNmsu5 https://t.co/72sYu1c59a #kidneycancer #oncology https://t.co/hitV1RzcXd
UroOncoNews Re: Clinical Validation of a Targeted Methylation-based Multi-cancer Early Detection Test Using an Independent Validation Set https://t.co/cmvt7L22AI
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/JKGzqm5vvT https://t.co/nHc1teTAOg
RT @TomPMarshall: @KateCushing2 @pash22 @NHSEngland @guardian @susan_bewley @MichaelBaum11 @BenMazer @oncology_bg @AaronGoodman33 @barttels…
@KateCushing2 @pash22 @NHSEngland @guardian @susan_bewley @MichaelBaum11 @BenMazer @oncology_bg @AaronGoodman33 @barttels2 @chadinabhan @VPrasadMDMPH "False +ve low at 0.5%" - conflates specificity & PPV Does this help? - Assume 99.5% specificity all Stages - 60yr old ♀; QCancer risk 1%; assume 0.25% each at Stages I to IV Stage I-II: Sensitivity 28% & PPV = 22% https://t.co/HQr33PgWtH https://t.co/17R2Cy7DnT
RT @jamecancerdoc: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation se…
RT @PaperbirdsO: New article: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent va…
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/Rnpkbcqp2G
Clinical #validation of a targeted methylation-based multi-cancer early #detection test using an independent validation set https://t.co/wdkVZwO8ze #Früherkennungstest #Früherkennung #Tumore #Onkologie
Clinical validation of a targeted #methylation-based multi-#cancer early #detection test using an independent validation set: https://t.co/IjvP4rmwKF
RT @jamecancerdoc: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation se…
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/aRH0UHcPqc #gyncsm "accurate reliable at identifying &locating cancer, ... some kinds for which there are now no effective screening methods.”
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/HYI5I1YWGt
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/5VY5M94ME2 https://t.co/mroR1rV5zn
血液を調べてのがん細胞由来のDNAメチル化を検出する事で様々な癌を検出できる可能性
New article: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/UJOIBPYTcC #kidneycancer #oncology https://t.co/Sp0uRevQsu
RT @jamecancerdoc: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation se…
RT @jamecancerdoc: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation se…
RT @bioinfosm: #cancer #blood test - #genomics #precisionmedicine Clinical validation of a targeted methylation-based multi-cancer early d…
#cancer #blood test - #genomics #precisionmedicine Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set - Annals of #Oncology https://t.co/DDbCTcssQ8
RT @jamecancerdoc: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation se…
RT @jamecancerdoc: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation se…
RT @jamecancerdoc: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation se…
RT @jamecancerdoc: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation se…
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set @EricKleinMD @CleClinicMD @ClevelandClinic @OncoAlert #CleClinicCancer @caseccc https://t.co/PpgxhZmjwT
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/QJ6YX13PUH
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @CleClinic_GUMRC: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation…
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @CleClinic_GUMRC: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation…
RT @drgandara: This just published. Ready for prime time? Big implications if so. Clinical validation of a targeted methylation-based mult…
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @drgandara: This just published. Ready for prime time? Big implications if so. Clinical validation of a targeted methylation-based mult…
RT @drgandara: This just published. Ready for prime time? Big implications if so. Clinical validation of a targeted methylation-based mult…
RT @drgandara: This just published. Ready for prime time? Big implications if so. Clinical validation of a targeted methylation-based mult…
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set - Annals of Oncology https://t.co/ONP8QCDh2x
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @EricKleinMD: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set…
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
Pre-symptom #blood #test that detects more than 50 #cancers rolled out: Clinical #validation of a targeted #methylation-based multi-cancer early detection test using an independent validation set https://t.co/5h5r8M6nvp
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set @Annals_Oncology https://t.co/LpXNj42Koo
RT @drgandara: This just published. Ready for prime time? Big implications if so. Clinical validation of a targeted methylation-based mult…
RT @drgandara: This just published. Ready for prime time? Big implications if so. Clinical validation of a targeted methylation-based mult…
RT @EricKleinMD: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set…
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set - Annals of Oncology https://t.co/VFVyfrNMMC
RT @EricKleinMD: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set…
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set - Annals of Oncology https://t.co/8Dwl7Ooz1Z
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/MRDDdiimCr
Seems Hopeful Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set #kahnchronicle https://t.co/jlhrfJrOdX
RT @CleClinic_GUMRC: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation…
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set @Annals_Oncology https://t.co/XLdfPCzlcX
RT @drgandara: This just published. Ready for prime time? Big implications if so. Clinical validation of a targeted methylation-based mult…
RT @drgandara: This just published. Ready for prime time? Big implications if so. Clinical validation of a targeted methylation-based mult…
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @CleClinic_GUMRC: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation…
This just published. Ready for prime time? Big implications if so. Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/SUDXGIc9Nm
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set - Annals of Oncology @Annals_Oncology @EricKleinMD @PCF_Science https://t.co/zQT1mn8zpq
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/3Q1HlFJqiF #Cancer
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set https://t.co/dgUmqvpdhx
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
RT @Annals_Oncology: Early detection could improve cure rates, mainly in cancers without screening modalities.
Early detection could improve cure rates, mainly in cancers without screening modalities.
10.1016/j.annonc.2021.05.806. Keywords. /Scientific community/Research programs/Cancer research; /Health and medicine/Medical specialties/Oncology/Cancer ...
doi: 10.1016/j.annonc. 2021.05.806 2. American Cancer Society. Cancer facts & figures 2022. https://bit.ly/3Nhlkxi [GRAIL, LLC. Data on file: GA-2021-0065].
2021;32(9):1167-77. DOI:https://doi.org/10.1016/j.annonc.2021.05.806. more. December 6 · deborahwilsonmd's profile picture. deborahwilsonmd. •.
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... 10.1016/S0140-6736(23)01700-2 2. US Preventive Services Task ... DOI:https://doi.org/10.1016/j.annonc.2021.05.806. more. December 6.
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doi: 10.1016/j.annonc.2021.05.806 2. American Cancer Society. Cancer facts & figures 2022. https://bit.ly/3Nhlkxi [GRAIL, LLC. Data on file ...
doi: 10.1016/j.annonc.2021.05.806. 3. Liu MC, Oxnard GR, Klein EA, et al. Sensitive and specific multi-cancer detection and localization ...
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doi: 10.1016/j.annonc.2021.05.806; GRAIL, Inc. False positive rate. [Data on file: GR-2025-0256]; Schrag D, Beer TM, McDonnell CH, et al ...
doi: 10.1016/j.annonc.2021.05.806; GRAIL, Inc. False positive rate. [Data on file: GR-2025-0256]; Schrag D, Beer TM, McDonnell CH, et al ...
doi: 10.1016/j.annonc.2021.05.806; GRAIL, Inc. False positive rate. [Data on file: GR-2025-0256]; Schrag D, Beer TM, McDonnell CH, et al ...
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doi: 10.1016/j.annonc.2021.05.806 2. American Cancer Society. Cancer facts & figures 2022. https://bit.ly/3Nhlkxi [GRAIL, LLC. Data on file ...
... 10.1016/j.annonc.2021.05.806 2. American Cancer Society. Cancer facts & figures 2022. https://bit.ly/3Nhlkxi [GRAIL, LLC. Data on file: GA ...
doi: 10.1016/j.annonc.2021.05.806 *Assumes screening is available for all colorectal, breast, prostate, cervical cancer cases, and 43% of ...
doi: 10.1016/j.annonc.2021.05.806 2. Schrag D, Beer TM, McDonnell CH, et al. Blood- based tests for multi-cancer early detection (PATHFINDER): ...
... detection test using an independent validation set. Ann Oncol. 2021 Sep;32(9):1167-77. doi: 10.1016/j.annonc.2021.05.806.
... detection test using an independent validation set. Ann Oncol. 2021 Sep;32(9):1167-77. doi: 10.1016/j.annonc.2021.05.806".
... 10.1016/j.annonc.2021.05.806 | Facebook. Log in. Facebook. No photo ... doi: 10.1016/j.annonc. 2021.05.806. Lan Pham and 5 others ·
doi: 10.1016/j.annonc.2021.05.806 *Assumes screening is available for all colorectal, breast, prostate, cervical cancer cases, and 43% of ...
https://doi.org/10.1016/j.annonc.2021.05.806; McCarthy, A. M., & Armstrong, K. (2014). The role of testing for BRCA1 and BRCA2 mutations in ...
... detection test using an independent validation set. Ann Oncol. 2021 Sep;32(9):1167-77. doi: 10.1016/j.annonc.2021.05.806.
Early detection is key to improving cancer outcomes. Adding multi-cancer early detection (MCED) testing to recommended screenings has the ...
... 10.1016/j.annonc.2021.05.806/asset/5ca8fc8f-0972-4583-a99a-3272bc774323/main.assets/gr3c_lrg.jpg. Полная статья здесь: https://www ...
... 10.1016/j.annonc.2021.05.806/asset/5ca8fc8f-0972-4583-a99a-3272bc774323/main.assets/gr3c_lrg.jpg. Artikel penuh kat sini: https://www ...
... 10.1016/j.annonc.2021.05.806/asset/5ca8fc8f-0972-4583-a99a-3272bc774323/main.assets/gr3c_lrg.jpg. Full article here: https://www ...
doi:10.1016/j.cell.2024.11.027; Iliff JJ, Wang M, Liao Y, et al. A paravascular pathway facilitates CSF flow through the brain parenchyma ...
Ann Oncol. 2021 Sep;32(9):1167-77. doi: 10.1016/j.annonc.2021.05.806; American Cancer Society. Cancer facts & ...
Kevin McFarland, a lieutenant with his local fire department, didn't think twice about taking a multi-cancer early detection (MCED) test ...
doi:10.1016/j.annonc.2021.05.806. 13. Shao SH, Allen B, Clement J, et al. Multi-cancer early detection test sensitivity for cancers with and ...
DOI: https://doi.org/10.1016/j.annonc.2021.05.806. GRAIL, Inc. Data on file: VV-TMF-59592 on clinical validation analysis in a subset of ...
doi: 10.1016/j.annonc.2021.05.806. Epub 2021 Jun 24. PMID: 34176681. Page 19. 19. What Do We Know about MCD. Cost? Page 20. 20. Costs of MCD ...
... 10.1016/j.annonc.2021.05.806 2. Schrag D, Beer TM, McDonnell CH, et al. Blood-based tests for multi-cancer early detection (PATHFINDER): a ...
Photo by Unidad Biotecnologia on December 12, 2025. May be an image of microscope.
doi: 10.1016/j.annonc.2021.05.806 3. Schrag D, Beer TM, McDonnell CH, et al. Blood-based tests for multi-cancer early detection (PATHFINDER): ...
doi: 10.1016/j.annonc. 2021.05.806 3. Schrag D, Beer TM, McDonnell CH, et al. Blood-based tests for multi-cancer early detection (PATHFINDER): ...
doi:10.1016/j.annonc.2021.05.806; Blevins Primeau AS. Time to cancer diagnosis after MCED testing in asymptomatic patients. Cancer Therapy ...
doi:10.1016/j.annonc.2021.05.806; Bao Y, Zhang D, Guo H, et al. Beyond blood: advancing the frontiers of liquid biopsy in oncology and ...
... . Klein A, et al. Annals of Oncology. 2021; 32 (9): 1167-1177. https://doi.org/10.1016/j.annonc.2021.05.806".
org/10.1016/j.annonc.2021.05.806.
doi: 10.1016/j.annonc.2021.05.806. We can now treat cancer far more effectively, but we can't treat what we haven't found. The Galleri multi ...
La prueba de sangre Galleri puede detectar hasta 50 tipos diferentes de cáncer y ya se ofrece en varios entornos (ver infografía). Si bien ...
DOI: https://doi.org/10.1016/j.annonc.2021.05.806. In 2024, an estimated 2,001,140 new cancer cases and 611,720 cancer deaths will occur in ...
Identifying and analyzing DNA shed by #cancer cells can help screen for some of the deadliest cancers that don't have recommended screening ...
doi:10.1016/j.annonc.2021.05.806; Schrag D, Beer TM, McDonnell CH 3rd, et al. Blood-based tests for multicancer early detection (PATHFINDER): ...
Ann Oncol. 2021;32(9):1167-1177. Doi: 10.1016/j.annonc.2021.05.806. American Cancer Society. Cancer Facts & ...
2021;32(9):1167-1177. Doi: 10.1016/j.annonc.2021.05.806. American Cancer Society . Cancer Facts & Figures. 2021. Available at ...
... results do occur. References: 1. Klein EA, et al. Ann Oncol. 2021;32(9):1167-1177. doi: 10.1016/j.annonc.2021.05.806.
... .ly/4589HRI References: 1. Klein EA, et al. Ann Oncol. 2021;32(9):1167-1177. doi: 10.1016/j.annonc.2021.05.806.
... . https://bit.ly/3MvVeZO. 3. Klein EA, et al. Ann Oncol. 2021;32(9):1167-1177. doi: 10.1016/j.annonc.2021.05.806.
... 1. https://bit.ly/3Zza98Z 2. Klein EA, et al. Ann Oncol. 2021;32(9):1167-1177. doi: 10.1016/j.annonc.2021.05.806.
doi: 10.1016/j.annonc.2021.05.806 2. American Cancer Society. Cancer facts & figures 2022. https://bit.ly/3Nhlkxi [GRAIL, LLC. Data on file ...
doi:10.1016/j.annonc.2021.05.806. Shao SH, Allen B, Clement J, et al. Multi-cancer early detection test sensitivity for cancers with and ...
doi:10.1016/j.annonc.2021.05.806. Last updated 29 July 2025 15:37. Citation: The Pharmaceutical Journal, PJ, September 2022, Vol 309, No 7965 ...
doi:10.1016/j.annonc.2021.05.806; Lee J, Kim HC, Kim ST, et al. Multimodal circulating tumor DNA (ctDNA) colorectal neoplasia detection assay ...
In the past, cfDNA has been harnessed to assess tumors that had already been identified, explained Michael J. ... doi:10.1016/j.annonc.2021.05.806 ...
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doi:10.1016/j.annonc.2021.05.806; Blood test for early detection of cancer: final study results support screening use. News release. European ...
Source: Annals of Oncology 24 June, 2021 DOI: 10.1016/j.annonc.2021.05.806 Clinical validation of a targeted methylation-based multi ...
org/10.1016/j.annonc.2021.05.806. [2] Blood test for early detection of cancer: final study results support screening use. Retrieved June 25 ...
CCGA的研究结果毫无疑问对GRAIL甚至对行业来说都是具有重要参考意义的，不过也有其局限性：如果在癌症患者进行活检后采集血液样本，与活检前相比， ...
doi.org/10.1016/j.annonc.2021.05.806. Currently rated 4.7 by 3 people. Posted in: Device / Technology News | Medical Condition News. Comments ...
2021;doi:10.1016/j.annonc.2021.05.806. “The goal is to improve the way we screen for cancer,” Eric A. Klein, MD, chairman of the Glickman ...
DOI. 10.1016/j.annonc.2021.05.806. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of ...
10.1016/j.annonc.2021.05.806. Figshare View on figshare. Download Download full text [pdf]. Europe PubMed Central 34176681. Pubmed 34176681 ...
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