PubHawk
Ann Surg November 2021 PMID 34183510

Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-label, Noninferiority Trial.

Laura Mora-López, Neus Ruiz-Edo, Oscar Estrada-Ferrer, Maria Luisa Piñana-Campón, Meritxell Labró-Ciurans, Jordi Escuder-Perez, Ricard Sales-Mallafré, Pere Rebasa-Cladera, Salvador Navarro-Soto, Xavier Serra-Aracil

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Mentions

40
Peak: 16 in Nov 2021
across 4 sources since Sep 2021

Extended reach

338,240
potential audience

Total likes

75

Video views

2,072

Mentions per month

Sep 2021 – Sep 2025

Where it's discussed

  • X / Twitter32 posts
  • Blogs4 articles
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The discussions highlight growing enthusiasm for the study's potential to change current treatment practices, with phrases like 'perfect jumping off point for a new outpatient study' and 'many don't need imaging and maybe now no abx' emphasizing optimism and evolving perspectives. The tone and terminology suggest a mix of support, curiosity, and cautious anticipation about the implications of adopting non-antibiotic strategies for mild diverticulitis.

AgreementModerate agreement

Most discussions express support or approval for the study findings, indicating that the idea of managing mild diverticulitis without antibiotics aligns with evolving medical practices.

InterestHigh interest

Posts show high curiosity and engagement, with many discussing the clinical implications and future research directions, hinting at an active interest in the topic.

EngagementModerate engagement

While some posts mainly acknowledge the study, others delve into the significance and potential shifts in treatment protocols, reflecting moderate but focused engagement.

ImpactModerate impact

The discussions suggest the study could influence clinical guidelines by reducing unnecessary antibiotic use, though some acknowledge further research is needed before widespread adoption.

Abstract in brief

  • The study found that treating mild acute diverticulitis (AD) without antibiotics on an outpatient basis is both safe and effective, with no significant difference in hospital admission rates compared to traditional antibiotic treatment.
  • Participants receiving nonantibiotic treatment showed similar rates of emergency department revisits and pain control compared to those receiving antibiotics, supporting the idea that antibiotics may not be necessary for mild AD.
  • The results suggest that outpatient management of mild AD with anti-inflammatory and symptomatic treatment alone is a reliable alternative to antibiotics, potentially reducing unnecessary antibiotic use.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Tamara McColl
@TamaraMcColl · X

EM Journal Club on this beautiful Winnipeg day reviewing the DINAMO study - antibiotics vs no-antibiotics in acute uncomplicated diverticulitis. No antibiotics non-inferior and supported by prior lit. @UManitoba_Emerg @um_research https://t.co/YCNuq1nNBr https://t.co/AmT7MxGOzN

Jun 6, 2023 · 13 likes · 1,353 followers View post →
バン@内科医のジレンマ
@lostphysicianYB · X

@klplKIPa49ZdaFy 治療期間の根拠は特になかったような。 強いて言えば1週間？ 軽症例は抗菌薬フリーで良いとする前向きが出たばかり。 この場合の対照群も7日間投与ですし。 https://t.co/GxIk4OBPoz

May 10, 2022 · 9 likes · 2 shares · 4,361 followers View post →
Annals of Surgery
@AnnalsofSurgery · X

Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-label, Noninferiority Trial https://t.co/MSRaQgZ5OL

Nov 11, 2021 · 7 likes · 6 shares · 56,618 followers View post →
トンヌラ
@37phoenix · X

軽症の憩室炎での抗菌薬非投与の外来治療は抗菌薬投与と比較して入院や救急外来受診を増やさなかった。DINAMO-study. Ann Surg. PMID:34183510.https://t.co/JyiOye6vzk

Sep 11, 2021 · 6 likes · 2,061 followers View post →
舛森 悠| Yu Masumori |総合診療
@Dr_mandheling · X

参考文献：https://t.co/8Gu7e1XO8l

Dec 14, 2022 · 5 likes · 9,461 followers View post →
Annals of Surgery
@AnnalsofSurgery · X

Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-label, Noninferiority Trial https://t.co/MSRaQgZ5OL

Nov 1, 2021 · 4 likes · 6 shares · 56,618 followers View post →

All mentions

Tamara McColl
@TamaraMcColl · X

EM Journal Club on this beautiful Winnipeg day reviewing the DINAMO study - antibiotics vs no-antibiotics in acute uncomplicated diverticulitis. No antibiotics non-inferior and supported by prior lit. @UManitoba_Emerg @um_research https://t.co/YCNuq1nNBr https://t.co/AmT7MxGOzN

Jun 6, 2023 · 13 likes · 1,353 followers View post →
Ali S. Raja, MD
@AliRaja_MD · X

RT @LWestafer: @1stJohnnyMac @TariqNoohani @Rick_Pescatore @EMNews @alimkakeng @AustinChiangMD @blondemedSJW @VenkBellamkonda @AliRaja_MD S…

Apr 23, 2023 · 1 share · 143,302 followers View post →
Lauren Westafer, DO MPH MS
@LWestafer · X

@1stJohnnyMac @TariqNoohani @Rick_Pescatore @EMNews @alimkakeng @AustinChiangMD @blondemedSJW @VenkBellamkonda @AliRaja_MD Several were before DINAMO, the largest RCT was published (Ie their search did not capture it based on time cutoffs eg ACP guidelines) https://t.co/FwplbIrVwQ

Apr 23, 2023 · 1 like · 1 share · 12,874 followers View post →
ソンチョー
@sontyo_ · X

軽症の憩室炎における外来治療AMPC/CVA投与 VS 無投与: RCT https://t.co/QEh6e8k2x2

Apr 9, 2023 · 2 likes · 534 followers View post →
舛森 悠| Yu Masumori |総合診療
@Dr_mandheling · X

参考文献：https://t.co/8Gu7e1XO8l

Dec 14, 2022 · 5 likes · 9,461 followers View post →
JACK
@gunpla08 · X

RT @lostphysicianYB: @klplKIPa49ZdaFy 治療期間の根拠は特になかったような。 強いて言えば1週間？ 軽症例は抗菌薬フリーで良いとする前向きが出たばかり。 この場合の対照群も7日間投与ですし。 https://t.co/GxIk4OBPoz

May 11, 2022 · 2 shares · 5,975 followers View post →
石油王
@BKNoil · X

RT @lostphysicianYB: @klplKIPa49ZdaFy 治療期間の根拠は特になかったような。 強いて言えば1週間？ 軽症例は抗菌薬フリーで良いとする前向きが出たばかり。 この場合の対照群も7日間投与ですし。 https://t.co/GxIk4OBPoz

May 10, 2022 · 2 shares · 3,920 followers View post →
バン@内科医のジレンマ
@lostphysicianYB · X

@klplKIPa49ZdaFy 治療期間の根拠は特になかったような。 強いて言えば1週間？ 軽症例は抗菌薬フリーで良いとする前向きが出たばかり。 この場合の対照群も7日間投与ですし。 https://t.co/GxIk4OBPoz

May 10, 2022 · 9 likes · 2 shares · 4,361 followers View post →
Dr. bycomet
@bycomet · X

憩室炎に抗菌薬なし https://t.co/nXPxM8Uhqh

Mar 21, 2022 · 7,949 followers View post →
肉親の骨をゆうパックで寺に送るな
@FjxliMfucAYJS59 · X

合併症のない急性憩室炎に貴様らは抗生剤投与をいつまで続けるつもりだ、21世紀だぞ、という論文 Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentr… https://t.co/SOLUuJml5U

Dec 23, 2021 · 1,807 followers View post →
Choosing Wisely Brasil
@ChooseWiselyBR · X

Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis - the DINAMO-study: https://t.co/e2dS2Arz9t

Dec 19, 2021 · 1 like · 3,881 followers View post →
James Wilson, DO, FACP, FAWM, CTropMed®
@JamesWilsonDO1 · X

Mild #diverticulitis in stable healthy patients does not require antibiotics. Mind you the study noted 24h of stabilization in the ED, but perfect jumping off point for a new #outpatient study! (1/6) https://t.co/XBuXXxFJcr

Nov 25, 2021 · 4 likes · 992 followers View post →
@Some4SurgeryITeam
@Some4SurgeryIT1 · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 12, 2021 · 6 shares · 5,486 followers View post →
Rodrigo Gomes da Silva MD, PhD
@RodrigogomesMD · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 11, 2021 · 6 shares · 448 followers View post →
Thales P. Batista, MD, PhD
@BatistaTP · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 11, 2021 · 6 shares · 1,287 followers View post →
mohamed salama
@M_A_Salama · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 11, 2021 · 6 shares · 54 followers View post →
DrLizMurphy
@DrLizMurphy · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 11, 2021 · 6 shares · 515 followers View post →
Laura
@Laura69247647 · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 11, 2021 · 6 shares · 39 followers View post →
Annals of Surgery
@AnnalsofSurgery · X

Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-label, Noninferiority Trial https://t.co/MSRaQgZ5OL

Nov 11, 2021 · 7 likes · 6 shares · 56,618 followers View post →
Joaquín Muñoz Rodríguez MD, PhD, FACS
@joaquinmmunoz · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 4, 2021 · 6 shares · 448 followers View post →
Marta G Bocanegra
@Martabocanegra7 · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 2, 2021 · 6 shares · 202 followers View post →
Davide Zattoni
@ZattoniDavide · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 1, 2021 · 6 shares · 144 followers View post →
Josh Burke
@_JoshBurke_ · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 1, 2021 · 6 shares · 3,171 followers View post →
Medical Research Library of Brooklyn
@DMCLibraryBKLYN · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 1, 2021 · 6 shares · 330 followers View post →
HerrDV
@HerrDV · X

RT @AnnalsofSurgery: Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre,…

Nov 1, 2021 · 6 shares · 459 followers View post →
Annals of Surgery
@AnnalsofSurgery · X

Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-label, Noninferiority Trial https://t.co/MSRaQgZ5OL

Nov 1, 2021 · 4 likes · 6 shares · 56,618 followers View post →
Eddy Lang
@EddyLang1 · X

EmergencyCare+ | Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-label, Noninferiority Trial. https://t.co/ArYPYfsfkv

Oct 30, 2021 · 1 like · 3,835 followers View post →
Jason Hine
@JayHineMD · X

What the hell to do w diverticulitis!?! Many dont need imaging and maybe now no abx. Yes, we're not there yet, but future will be interesting. https://t.co/HVCm16TKhJ

Oct 26, 2021 · 1 like · 988 followers View post →
Biobanc IISPV
@Biobanco_IISPV · X

RT @hjoan23: #hjoan23publica a @AnnalsofSurgery

Oct 22, 2021 · 3 shares · 68 followers View post →
Atenció Primària ICS Camp de Tarragona
@apicstgn · X

RT @hjoan23: #hjoan23publica a @AnnalsofSurgery

Oct 22, 2021 · 3 shares · 888 followers View post →
Hospital Universitari Joan XXIII
@hjoan23 · X

#hjoan23publica a @AnnalsofSurgery

Oct 22, 2021 · 1 like · 3 shares · 5,899 followers View post →
トンヌラ
@37phoenix · X

軽症の憩室炎での抗菌薬非投与の外来治療は抗菌薬投与と比較して入院や救急外来受診を増やさなかった。DINAMO-study. Ann Surg. PMID:34183510.https://t.co/JyiOye6vzk

Sep 11, 2021 · 6 likes · 2,061 followers View post →