Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after glucose normalization. Why glucose control alone may not be enough for #ASCVD risk reduction in #diabetes https://t.co/aFbvfB6LRZ #AHAJournals https://t.co/KyCqQWlXMv
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis.
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Jul 2021 – Mar 2025Where it's discussed
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X / Twitter43 posts
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News8 articles
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Blogs4 articles
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Reddit3 posts
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YouTube2 videos
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Facebook2 posts
AI synopsis
What people are saying
The collection reflects a high level of agreement and interest, with posts emphasizing the importance of hyperglycemia in promoting immune changes that lead to artery disease, exemplified by phrases like 'promotes persistent proatherogenic characteristics' and 'epigenetic priming.' The use of scientific terminology and references to ongoing research indicate deep engagement and recognition of the study's potential impact on medical practices.
Most discussions emphasize the significance of hyperglycemia's role in immune cell reprogramming and atherosclerosis, showing strong consensus with positive language.
Posts demonstrate high interest through references to immunology, cardiovascular risk, and mentions of ongoing research, indicating enthusiasm and engagement with the topic.
While many posts echo the study's findings, some include detailed quotes or calls to action, suggesting active engagement with the science rather than superficial comments.
The widespread sharing of the research and comments about its relevance to cardiovascular health imply that these discussions recognize the study's potential to influence medical understanding and future treatments.
Abstract in brief
- Study investigates how high blood sugar (hyperglycemia) affects immune cells (macrophages) in diabetes, leading to an increased risk of cardiovascular disease.
- Experiments using macrophages from diabetic mice showed they become "trained" to exhibit inflammatory behaviors even when glucose levels are normal, suggesting a lasting impact from prior high glucose exposure.
- Bone marrow transplants from diabetic mice into healthy mice showed that this training can contribute to more severe artery disease, indicating that changes in immune cell behavior due to diabetes can promote ongoing cardiovascular issues.
Top posts
Most liked on X and Bluesky'Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis' (@CircAHA) A huge collaborative work to progress understanding of trained immunity associated with hyperglycaemia. Congratulations to all involved. https://t.co/h0HjIC863h https://t.co/onco8r4EcZ
Sugar makes your macrophages remember! Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis: https://t.co/sYudQa91vF #diabetes #cardiovascular #macrophage
After 7 years of hard work, Edgar & Akbar et al. is finally out for all to enjoy
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis @CircAHA https://t.co/50E9d8mI1e
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/oE7otcW2oZ
All mentions
Impact of Hyperglycemia on Immune Cells and Cardiovascular Risk
This study investigates how high blood sugar affects immune cells, causing them to become 'trained' and promote artery disease even after glucose levels normalize. The findings highlight the lasting impact of…
High Blood Sugar's Impact on Vascular and Immune System Health
This video explores how high blood sugar damages blood vessels and alters immune responses, increasing inflammation. It highlights the role of hyperglycemia in cardiovascular disease and how diet and exercise can reduce…
This Works Better than Stem Cells - 5 Ways to Increase Stem Cells Naturally https://t.co/8IRuKdSZNa via @YouTube
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#Paasto stimuloi muuten kantasoluja! https://t.co/dRmDnG8mKz https://t.co/KfHJMC8L7k
https://t.co/wrTE9TRwb7
High blood sugar levels 'reprogram' stem cells https://t.co/EtjHDT4aIs https://t.co/p9u46ubJ5z https://t.co/t7xQbe1tF9
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis @CircAHA https://t.co/50E9d8mI1e
RT @CircAHA: ICYMI Hyperglycemia Induces Trained Immunity https://t.co/i7tqMegbnQ
RT @CircAHA: ICYMI Hyperglycemia Induces Trained Immunity https://t.co/i7tqMegbnQ
RT @CircAHA: ICYMI Hyperglycemia Induces Trained Immunity https://t.co/i7tqMegbnQ
Sugar makes your macrophages remember! Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis: https://t.co/sYudQa91vF #diabetes #cardiovascular #macrophage
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/oE7otcW2oZ
RT @NicolaiWorm: "We hypothesized that #hyperglycemia induces trained immunity in macrophages, promoting persistent proatherogenic characte…
"We hypothesized that #hyperglycemia induces trained immunity in macrophages, promoting persistent proatherogenic characteristics." https://t.co/KDfnuSvD8r @lowcarbGP @davidludwigmd
RT @JRockDataSci1: Hyperglycemia reprograms stem cells toward production of pro-inflammatory pro-atherogenic macrophages which may later be…
RT @JRockDataSci1: Hyperglycemia reprograms stem cells toward production of pro-inflammatory pro-atherogenic macrophages which may later be…
"High levels of #glucose in the blood "reprogram" stem cells, leading to a lasting increase in the risk of developing dangerous #atherosclerosis." #heartdisease #bloodsugar https://t.co/kSqaxmROZx
RT @JRockDataSci1: Hyperglycemia reprograms stem cells toward production of pro-inflammatory pro-atherogenic macrophages which may later be…
RT @JRockDataSci1: Hyperglycemia reprograms stem cells toward production of pro-inflammatory pro-atherogenic macrophages which may later be…
Hyperglycemia reprograms stem cells toward production of pro-inflammatory pro-atherogenic macrophages which may later become foam cells. https://t.co/Qajzv6bd74 @PeterAttiaMD @BenBikmanPhD @DaveKeto @virtahealth @DrSarahHallberg @gerdosi
'Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis' (@CircAHA) A huge collaborative work to progress understanding of trained immunity associated with hyperglycaemia. Congratulations to all involved. https://t.co/h0HjIC863h https://t.co/onco8r4EcZ
RT @CircAHA: Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after gl…
RT @CircAHA: Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after gl…
RT @CircAHA: Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after gl…
RT @CircAHA: Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after gl…
RT @CircAHA: Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after gl…
RT @CircAHA: Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after gl…
RT @CircAHA: Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after gl…
RT @CircAHA: Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after gl…
RT @CircAHA: Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after gl…
RT @CircAHA: Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after gl…
Hyperglycaemia promotes epigenetic priming of macrophage precursors & persistent pro-atherogenic characteristics even after glucose normalization. Why glucose control alone may not be enough for #ASCVD risk reduction in #diabetes https://t.co/aFbvfB6LRZ #AHAJournals https://t.co/KyCqQWlXMv
After 7 years of hard work, Edgar & Akbar et al. is finally out for all to enjoy
Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/W8tT9YzCPo
@abledoc @AskDrShashank Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/vfCXqFmXRC
@exceedhergrasp1 @GemzME @Tweet_Nutrition @KendaRigdon Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/4sU6ZzlJYy
Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis | Circulation https://t.co/V8DTsmsCAf
Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/9dHMgH8XHM
RT @sgoto4: Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/QNYmPMbhw…
RT @sgoto4: Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/QNYmPMbhwb
Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/QNYmPMbhwb
Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/QNYmPMbhwb高血糖と動脈硬化の関連がわかるかな?
https://t.co/NhokZ0vcJ7
Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis https://t.co/u3KzcxkXlh