PubHawk
Proc Natl Acad Sci U S A July 2021 PMID 34260385

Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence.

Hao-Ming Dong, Daniel S Margulies, Xi-Nian Zuo, Avram J Holmes

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Mentions

12
Peak: 4 in Nov 2020
across 3 sources since Nov 2020

Extended reach

181,762
potential audience

Total likes

284

Video views

11,352

Mentions per month

Nov 2020 – Dec 2025

Where it's discussed

  • News6 articles
  • X / Twitter4 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions generally express strong agreement with the study’s findings, evident in phrases like 'important insight into brain development.' Several posts delve into specifics, such as mentioning the gradual maturation of cortices and how this relates to cognitive growth, showing interest and engagement. The tone varies from academic to cautiously optimistic about the potential influence of this research on developmental neuroscience.

AgreementModerate agreement

Most discussions recognize the importance of the study in understanding brain development, reflecting a general consensus about its relevance.

InterestHigh interest

Numerous posts show high curiosity, with many discussing specific findings like the maturation of association areas and default networks.

EngagementModerate engagement

Posts often reference the methods used, such as fMRI data, and explore implications for cognitive and social development, indicating active engagement.

ImpactModerate impact

Participants acknowledge that the findings could influence future research and understanding of adolescence, highlighting moderate perceived impact.

Abstract in brief

  • The study investigates how large-scale brain organization, specifically the functional gradients in the cortex, change from childhood to adolescence, highlighting shifts from sensory/motor regions to more complex association areas.
  • Using resting-state fMRI data from 190 individuals aged 6-17, the research shows that the brain's gradient patterns gradually mature, reaching an adult-like organization around ages 13-14, with key changes observed in the default network and sensory/motor areas.
  • The findings suggest that different brain networks mature at different rates, with sensory/motor regions developing early and association areas like the medial prefrontal cortex maturing later during adolescence, which may influence cognitive and social development.
Read the full abstract

Top posts

Most liked on X and Bluesky
CLaE
@leafs_s · X

Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence https://t.co/asd25d3YGr

Nov 21, 2020 · 6 likes · 28,855 followers View post →
bioRxiv
@biorxivpreprint · X

Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence https://t.co/3yHmoxFj8V #bioRxiv

Nov 18, 2020 · 1 like · 138,512 followers View post →
aDNA_papers
@aDNA_papers · X

Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence https://t.co/A0GZt94llj

Nov 18, 2020 · 1,697 followers View post →
Rosaura Brisuela @roswitta.bsky.social
@Roswitamind · X

Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence https://t.co/7jAFLRTFco

Nov 25, 2020 · 1,287 followers View post →

All mentions

Rosaura Brisuela @roswitta.bsky.social
@Roswitamind · X

Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence https://t.co/7jAFLRTFco

Nov 25, 2020 · 1,287 followers View post →
CLaE
@leafs_s · X

Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence https://t.co/asd25d3YGr

Nov 21, 2020 · 6 likes · 28,855 followers View post →
aDNA_papers
@aDNA_papers · X

Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence https://t.co/A0GZt94llj

Nov 18, 2020 · 1,697 followers View post →
bioRxiv
@biorxivpreprint · X

Shifting gradients of macroscale cortical organization mark the transition from childhood to adolescence https://t.co/3yHmoxFj8V #bioRxiv

Nov 18, 2020 · 1 like · 138,512 followers View post →
Adolescent maturation of cortical excitation-inhibition ratio based on ...
News

U.S.A. 118, e2024448118 (2021). Crossref · PubMed · Web of Science ... https://doi.org/10.1073/pnas.2506513122 · Crossref. Loading... Citation ...

Jun 4, 2025 View →
Adolescent maturation of cortical excitation-inhibition ratio based on ...
News

U.S.A. 118, e2024448118 (2021). GO TO REFERENCE. Crossref ... https://doi.org/10.1073/pnas.2506513122 · Crossref. Loading... Citation ...

Jun 4, 2025 View →
Cortical gradients of functional integration | CORTIGRAD | Project ...
News

DOI: 10.1073/pnas.2024448118. Non-peer reviewed articles (1). Gradients in brain organization (opens in new window). Author(s): Bernhardt ...

Apr 28, 2025 View →
Cortical gradients of functional integration | CORTIGRAD | Projet ...
News

DOI: 10.1073/pnas.2024448118. Non-peer reviewed articles (1). Gradients in brain organization (s'ouvre dans une nouvelle fenêtre). Auteurs ...

Apr 28, 2025 View →
Macroscale connectome topographical structure reveals the ...
News

U.S.A. 118, e2024448118 (2021). Crossref · PubMed · Web of Science ... https://doi.org/10.1073/pnas.2417010122 · Crossref. Juntao Zhao,; Yunyun ...

Oct 11, 2024 View →
Macroscale connectome topographical structure reveals the ...
News

U.S.A. 118, e2024448118 (2021). GO TO REFERENCE. Crossref ... https://doi.org/10.1073/pnas.2417010122 · Crossref. Juntao Zhao,; Yunyun ...

Oct 11, 2024 View →