Cureus June 2021 PMID 34290927

Frank's Sign in Polycystic Ovary Syndrome and Sideburn Adiposity: A Case Report and Illustrated Hypothesis.

Mohammed Abrahim

Mentions

22
Peak: 5 in Jul 2021
across 5 sources since Jul 2021

Extended reach

13,803
potential audience

Total likes

13

Video views

573

Mentions per month

Jul 2021 – Sep 2025

Where it's discussed

  • X / Twitter12 posts
  • Facebook6 posts
  • YouTube2 videos
  • News1 articles
  • Blogs1 articles

AI synopsis

What people are saying

The overall discussions demonstrate enthusiastic curiosity, with participants recognizing potential links between Frank's sign and PCOS, exemplified by phrases such as 'Have you noticed' and 'Also, Frank's sign could be a sign,' which indicate interest in observational findings. The tone is exploratory, emphasizing the possibility of new diagnostic indicators, yet the engagement remains moderate, reflecting interest but limited in-depth analysis at this stage.

AgreementStrong agreement

Most discussions agree that Frank's sign could be linked to PCOS, as multiple posters acknowledge this possible association based on their observations.

InterestHigh interest

The comments show high curiosity about the potential clinical significance, with many posters noting visual signs like ear creases in young women with PCOS.

EngagementModerate engagement

Posts reflect some depth, with users referencing the specifics of the case report and considering its implications, but mostly through brief mentions and questions.

ImpactModerate impact

While the discussions highlight potential diagnostic insights, the overall influence appears preliminary, suggesting an emerging hypothesis rather than a widely adopted clinical practice.

Abstract in brief

  • The article discusses a case report where a young woman with Polycystic Ovary Syndrome (PCOS) also shows Franks sign, a diagonal earlobe crease, which has traditionally been linked to aging and cardiometabolic diseases.
  • The author suggests that finding Franks sign in young women could serve as a clinical indicator prompting further investigation for PCOS.
  • An hypothesis is proposed that both Franks sign and PCOS may share a common underlying cause related to visceral adiposity (fat accumulation) around the face, which might explain their association.

Top posts

Most liked on X and Bluesky
DoctorAbrahim
@doctorabrahim · X

@drsamshuaibi Ear creases could also occur in young individuals with visceral/ facial obesity such as in PCOS. https://t.co/ZsOyvNPpad

Sep 5, 2023 · 3 likes · 1 share · 55 followers View post →
Adipose Papers
@adipose_papers · X

Frank's Sign in Polycystic Ovary Syndrome and Sideburn Adiposity: A Case Report and Illustrated Hypothesis https://t.co/Tp4pNlsFAO https://t.co/amNP9Kt99x

Jul 22, 2021 · 1 like · 2,484 followers View post →
DoctorAbrahim
@doctorabrahim · X

@BrianElliottMD1 Frank's sign also occurs in young females with visceral facial obesity as in PCOS https://t.co/ZsOyvO701L

Sep 27, 2022 · 1 like · 55 followers View post →
DoctorAbrahim
@doctorabrahim · X

Frank’s Sign in Polycystic Ovary Syndrome and Sideburn Adiposity: A Case Report and Illustrated Hypothesis https://t.co/lEOtJ0BiqN #PCOS #PCOD @CureusInc #diagonalearlobecrease #earlobecrease #frankssign #casereport #researchpaper

Jul 21, 2021 · 1 like · 2 shares · 55 followers View post →
Dr LG (is a longhauler)
@subversivepsych · X

RT @doctorabrahim: @drsamshuaibi Ear creases could also occur in young individuals with visceral/ facial obesity such as in PCOS. https://…

Sep 22, 2023 · 1 share · 5,199 followers View post →
Cureus
@CureusMedical · X

RT @doctorabrahim: Frank’s Sign in Polycystic Ovary Syndrome and Sideburn Adiposity: A Case Report and Illustrated Hypothesis https://t.co/…

Jul 21, 2021 · 2 shares · 4,553 followers View post →

All mentions

Dr LG (is a longhauler)
@subversivepsych · X

RT @doctorabrahim: @drsamshuaibi Ear creases could also occur in young individuals with visceral/ facial obesity such as in PCOS. https://…

Sep 22, 2023 · 1 share · 5,199 followers View post →
DoctorAbrahim
@doctorabrahim · X

@drsamshuaibi Ear creases could also occur in young individuals with visceral/ facial obesity such as in PCOS. https://t.co/ZsOyvNPpad

Sep 5, 2023 · 3 likes · 1 share · 55 followers View post →
DoctorAbrahim
@doctorabrahim · X

@tatertotsmcgee Have you noticed Frank's sign in PCOS? https://t.co/ZsOyvNPWZL

Oct 13, 2022 · 55 followers View post →
DoctorAbrahim
@doctorabrahim · X

@queenveej Have you noticed Frank's sign in PCOS? https://t.co/ZsOyvNPWZL

Oct 13, 2022 · 55 followers View post →
DoctorAbrahim
@doctorabrahim · X

@lolacoaster Have you noticed Frank's sign in PCOS? https://t.co/ZsOyvNPWZL

Oct 13, 2022 · 55 followers View post →
DoctorAbrahim
@doctorabrahim · X

@BrianElliottMD1 Frank's sign also occurs in young females with visceral facial obesity as in PCOS https://t.co/ZsOyvO701L

Sep 27, 2022 · 1 like · 55 followers View post →
DoctorAbrahim
@doctorabrahim · X

@heidithewiz Also, Frank's sign could be a sign of PCOS https://t.co/ZsOyvNPWZL

Sep 27, 2022 · 55 followers View post →
JoeCannonMS
@JoeCannonMS · X

Diagnoal ear lobe crease and PCOS in 23 yr old female. Connection? https://t.co/M3KzQ3TaqG

Jul 23, 2021 · 500 followers View post →
Adipose Papers
@adipose_papers · X

Frank's Sign in Polycystic Ovary Syndrome and Sideburn Adiposity: A Case Report and Illustrated Hypothesis https://t.co/Tp4pNlsFAO https://t.co/amNP9Kt99x

Jul 22, 2021 · 1 like · 2,484 followers View post →
Cureus
@CureusMedical · X

RT @doctorabrahim: Frank’s Sign in Polycystic Ovary Syndrome and Sideburn Adiposity: A Case Report and Illustrated Hypothesis https://t.co/…

Jul 21, 2021 · 2 shares · 4,553 followers View post →
PCOS_BOT
@BotPcos · X

RT @doctorabrahim: Frank’s Sign in Polycystic Ovary Syndrome and Sideburn Adiposity: A Case Report and Illustrated Hypothesis https://t.co/…

Jul 21, 2021 · 2 shares · 14 followers View post →
DoctorAbrahim
@doctorabrahim · X

Frank’s Sign in Polycystic Ovary Syndrome and Sideburn Adiposity: A Case Report and Illustrated Hypothesis https://t.co/lEOtJ0BiqN #PCOS #PCOD @CureusInc #diagonalearlobecrease #earlobecrease #frankssign #casereport #researchpaper

Jul 21, 2021 · 1 like · 2 shares · 55 followers View post →
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