... 10.1177/2047487320905721 (Epub ahead of print). 22. Mach F et al., Eur Heart J 2020, 41:111–188. 23. Koren JM, J Am Coll Cardiol 2019, 74:2132 ...
A scoring system for predicting individual treatment effects of statins in type 2 diabetes patients on haemodialysis.
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Mar 2020 – Jan 2026Where it's discussed
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What people are saying
The overall discussion demonstrates a genuine curiosity about the clinical implications of the scoring system, with phrases like 'potential impact' and 'personalized care' indicating a nuanced understanding. The tone varies from cautious optimism to recognition of risks, reflecting a balanced perspective on the study's significance.
The discussion acknowledges the potential and relevance of the research, with some optimism about personalized care.
Participants show a moderate interest, noting the importance of biomarkers and personalized treatment options.
Tweets reflect thoughtful engagement, mentioning biomarkers, potential benefits, and risks involved.
The conversation recognizes some potential impact, but also highlights uncertainties and the need for further validation.
Abstract in brief
- Researchers developed a scoring system using specific patient markers to predict how individuals with type 2 diabetes on haemodialysis will respond to statin therapy, identifying those who may benefit, be neutral, or be harmed.
- The study analyzed data from the 4D trial involving over 1,200 patients, creating two scores based on different sets of markers, which successfully stratified patients into groups with varying treatment effects and mortality outcomes.
- The score incorporates markers linked to mechanisms like cholesterol metabolism and atherosclerosis, providing a potential clinical tool to personalize statin treatment, maximizing benefits while minimizing risks for haemodialysis patients.
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Potential impact of statins on people with diabetes on haemodialysis: - 1/3 benefit - 1/3 no effect - 1/3 may die Biomarkers could predict statin use for personalised care in the future. @schuler_jochen @DrAseemMalhotra @BritRenalSoc https://t.co/8BBnwQwoHU
DOI: 10.1177/2047487320905721 https://doi.org/10.1177/2047487320905721. *Deutsche Diabetes Dialyse Studie (4D-. Studie). Randomized Controlled ...
https://doi.org/10.1177/2047487320905721. Bilder. Dialysepatienten haben ein hohes Risiko für Herz-Kreislauf-Erkrankungen < Dialysepatienten ...
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