August 2021 PMID 34387126

Pacemaker-Based Cardiac Neuromodulation Therapy in Patients With Hypertension: A Pilot Study.

Zbigniew Kalarus, Béla Merkely, Petr Neužil, Marcin Grabowski, Przemysław Mitkowski, Germanas Marinskis, Andrejs Erglis, Jarosław Kaźmierczak, Thomas Sturmberger, Adam Sokal, Slawomir Pluta, László Gellér, István Osztheimer, Filip Malek, Agnieszka Kolodzińska

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Mentions

30
Peak: 1 in Aug 2021
across 4 sources since Aug 2021

Extended reach

32,082
potential audience

Total likes

12

Video views

752

Mentions per month

Aug 2021 – Apr 2025

Where it's discussed

  • News24 articles
  • YouTube3 videos
  • Facebook2 posts
  • X / Twitter1 posts

AI synopsis

What people are saying

These discussions highlight the promising results of the study, with comments like 'significantly reduced BP' and references to the 'MODERATO II controlled study,' indicating interest in innovative treatment options. The tone remains positive yet measured, emphasizing the potential of pacemaker-based cardiac neuromodulation without overly optimistic claims, reflecting moderate engagement and perceived impact.

AgreementModerate agreement

Most discussions acknowledge the positive findings of the study, mentioning the significant BP reductions observed in the research.

InterestModerate interest

The mentions demonstrate moderate curiosity, focusing on the potential clinical implications without delving into technical details.

EngagementModerate engagement

Participants show some engagement by referencing specific study outcomes and commentaries, but their involvement remains relatively surface-level.

ImpactModerate impact

There is a recognition that the findings could influence future hypertension treatments, although the discussions remain cautious and exploratory.

Abstract in brief

  • The study investigated the effects of a cardiac neuromodulation therapy (CNT) using a pacemaker device called Moderato on lowering blood pressure in hypertensive patients, finding that it significantly reduced 24-hour ambulatory systolic blood pressure after 6 months.
  • Patients with hypertension who received the CNT showed an average reduction of about 11 mmHg in their systolic blood pressure, compared to a smaller reduction in the control group, with no significant adverse effects reported.
  • Most participants had isolated systolic hypertension and were already on multiple antihypertensive medications, and the results suggest that CNT via pacemaker could be a promising additional treatment for managing high blood pressure.]

Top posts

Most liked on X and Bluesky
JAHA
@JAHA_AHA · X

Backbeat CNT significantly reduced BP in a MODERATO II randomized controlled study of hypertensive pacemaker patients. https://t.co/oZ3rpZO3u6 @BurkhoffMD @OrchestraBioMed #AHAJournals https://t.co/HPrV4urBcz

Aug 24, 2021 · 2 likes · 31,332 followers View post →

All mentions

JAHA
@JAHA_AHA · X

Backbeat CNT significantly reduced BP in a MODERATO II randomized controlled study of hypertensive pacemaker patients. https://t.co/oZ3rpZO3u6 @BurkhoffMD @OrchestraBioMed #AHAJournals https://t.co/HPrV4urBcz

Aug 24, 2021 · 2 likes · 31,332 followers View post →