Mol Neurodegener August 2021 PMID 34454574

Extracellular protein components of amyloid plaques and their roles in Alzheimer's disease pathology.

M Mahafuzur Rahman, Christofer Lendel

Mentions

10
Peak: 3 in Aug 2021
across 3 sources since Aug 2021

Extended reach

20,949
potential audience

Total likes

47

Video views

290

Mentions per month

Aug 2021 – Apr 2025

Where it's discussed

  • X / Twitter6 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The overall discussions demonstrate moderate support and curiosity about the article, exemplified by phrases like 'new article' and hashtags related to Alzheimer's and neurology, which indicate interest but lack detailed critique or engagement. The tone is neutral and informative, emphasizing the publication's relevance while not delving into technical or controversial implications.

AgreementModerate agreement

The posts show a positive attitude toward the research, acknowledging its relevance to Alzheimer's disease understanding.

InterestModerate interest

Participants show moderate curiosity by sharing the publication and discussing its focus on amyloid plaques.

EngagementNeutral engagement

Most comments are brief, mainly sharing or referencing the article without in-depth analysis.

ImpactModerate impact

The posts suggest that the publication is influential within the field, but the overall discourse remains introductory.

Abstract in brief

  • This review explains that Alzheimer’s disease (AD) is characterized by the buildup of amyloid-beta (A) peptides in plaques outside neurons and tau proteins inside them, and while much research has focused on A, other extracellular proteins also play important roles in the disease.
  • It highlights how the deposition of specific proteins in these plaques can disrupt the normal protein networks within the brain, potentially contributing to AD development and related conditions.
  • The paper discusses current research methods, like top-down analyses of postmortem tissue and bottom-up approaches for understanding protein organization in plaques, as well as a network analysis of proteins that interact with A, to better understand their roles in AD pathology.

Top posts

Most liked on X and Bluesky
Molecular Neurodegeneration
@MolNeuro · X

'#Extracellular protein components of #amyloid plaques and their roles in #AlzheimersDisease pathology' @KTHuniversity https://t.co/UuaUaxEGzU https://t.co/tnWzkA3rXG

Aug 31, 2021 · 7 likes · 1 share · 2,943 followers View post →
BrightFocus Foundation
@_BrightFocus · X

RT @MolNeuro: '#Extracellular protein components of #amyloid plaques and their roles in #AlzheimersDisease pathology' @KTHuniversity http…

Aug 31, 2021 · 1 share · 17,148 followers View post →
Paperbirds_Neurology
@PaperbirdsN · X

New article: Extracellular protein components of amyloid plaques and their roles in Alzheimer's disease pathology https://t.co/omBlypmvG6 #alzheimers #neurology https://t.co/eGpXiSsRdD

Aug 30, 2021 · 457 followers View post →
es/iode
@es_iode · X

Mar 1, 2023 · 36 followers View post →
es/iode
@es_iode · X

Jan 8, 2023 · 36 followers View post →
es/iode
@es_iode · X

Dec 17, 2022 · 36 followers View post →

All mentions

es/iode
@es_iode · X

Mar 1, 2023 · 36 followers View post →
es/iode
@es_iode · X

Jan 8, 2023 · 36 followers View post →
es/iode
@es_iode · X

Dec 17, 2022 · 36 followers View post →
BrightFocus Foundation
@_BrightFocus · X

RT @MolNeuro: '#Extracellular protein components of #amyloid plaques and their roles in #AlzheimersDisease pathology' @KTHuniversity http…

Aug 31, 2021 · 1 share · 17,148 followers View post →
Molecular Neurodegeneration
@MolNeuro · X

'#Extracellular protein components of #amyloid plaques and their roles in #AlzheimersDisease pathology' @KTHuniversity https://t.co/UuaUaxEGzU https://t.co/tnWzkA3rXG

Aug 31, 2021 · 7 likes · 1 share · 2,943 followers View post →
Paperbirds_Neurology
@PaperbirdsN · X

New article: Extracellular protein components of amyloid plaques and their roles in Alzheimer's disease pathology https://t.co/omBlypmvG6 #alzheimers #neurology https://t.co/eGpXiSsRdD

Aug 30, 2021 · 457 followers View post →