J Synchrotron Radiat September 2021 PMID 34475312

Robotic sample changers for macromolecular X-ray crystallography and biological small-angle X-ray scattering at the National Synchrotron Light Source II.

Edwin O Lazo, Stephen Antonelli, Jun Aishima, Herbert J Bernstein, Dileep Bhogadi, Martin R Fuchs, Nicolas Guichard, Sean McSweeney, Stuart Myers, Kun Qian, Dieter Schneider, Grace Shea-McCarthy, John Skinner, Robert Sweet, Lin Yang

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Mentions

Peak: 2 in Aug 2021

across 2 sources since Aug 2021

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4,980

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209

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Aug 2021 – Dec 2021

Where it's discussed

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AI synopsis

What people are saying

Overall, the discussions reflect strong agreement and high interest, with examples such as praise for the automation capabilities and references to enhancing research productivity. The tone underscores the significance of these developments, indicating their potential to reshape structural biology techniques and experimental efficiency.

AgreementStrong agreement

Most discussions strongly support the benefits and innovation of the robotic sample changers, emphasizing their importance in experimental efficiency.

InterestHigh interest

Comments demonstrate high curiosity and interest, with interest expressed through praise and mentions of technological advancements.

EngagementModerate engagement

Participants actively engage by sharing thoughts on automation, technical details, and potential applications, though some simply acknowledge the work.

ImpactHigh impact

The discussions highlight the significant impact of these systems on crystallography and bioSAXS research, suggesting transformative potential for lab workflows.

Abstract in brief

The text describes the development of robotic sample changers used at the National Synchrotron Light Source II for macromolecular X-ray crystallography (MX) and biological small-angle X-ray scattering (bioSAXS), designed to enable fully automated data collection and remote access.
Both systems are built around a six-axis industrial robotic arm with specialized end effectors, featuring software that ensures high-throughput, robustness, and efficient resource sharing, with compatibility for standard sample formats like SPINE bases and Unipucks.
The MX system, introduced in 2017, can hold up to 384 samples and uses machine vision for precise sample handling, while the bioSAXS system, deployed in 2019, manages about 360 samples at controlled temperatures, enhancing sample storage and handling capabilities for these experiments.]

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All mentions

Automated Robotic Sample Changers for MX and bioSAXS at NSLS-II

Robotic sample changers for macromolecular X-ray crystallography and bioSAXS at NSLS-II enable automated, remote data collection. Both systems use a six-axis robotic arm, high-throughput design, and standard sample…

International Union of Crystallography · Oct 13, 2021 105 views

Robotic Sample Changers for MX and bioSAXS at NSLS-II

Robotic sample changers at NSLS-II enable automated, remote data collection for macromolecular crystallography and bioSAXS. Featuring six-axis robotic arms and compatibility with standard sample formats, these systems…

International Union of Crystallography · Oct 13, 2021 104 views

J Synchrotron Rad

@JSynchrotronRad · X

Dec 23, 2021 · 1,446 followers View post →

John R Helliwell

@HelliwellJohn · X

RT @JSynchrotronRad: Edwin O. Lazo et al.: Robotic sample changers for macromolecular X-ray crystallography and biological small-angle X-ra…

Aug 24, 2021 · 1 share · 1,876 followers View post →