August 2021 PMID 34505026

Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis.

Safi U Khan, Ahmad N Lone, Muhammad Shahzeb Khan, Salim S Virani, Roger S Blumenthal, Khurram Nasir, Michael Miller, Erin D Michos, Christie M Ballantyne, William E Boden, Deepak L Bhatt

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Mentions

282

Peak: 69 in Jul 2021

across 6 sources since Jul 2021

Extended reach

1,310,033

potential audience

Total likes

9,933

Video views

401,681

Mentions per month

Jul 2021 – Jul 2025

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AI synopsis

What people are saying

The discussions reflect a generally positive view of the publication, highlighting its findings that omega-3s, especially EPA, reduce cardiovascular mortality, with participants citing studies and emphasizing implications for health. The tone ranges from supportive to cautious, with some skeptics questioning benefits but overall engagement remains high, demonstrating the article's relevance in ongoing health conversations.

AgreementModerate agreement

Most posts acknowledge the positive effects of omega-3s on cardiovascular health, with some emphasizing the greater benefits of EPA alone.

InterestModerate interest

Discussions show moderate curiosity, referencing specific studies and results but not delving deeply into methodology or controversies.

EngagementHigh engagement

Many posts actively discuss the implications, such as benefits and potential risks, and cite related research, indicating deep interest.

ImpactModerate impact

The frequent referencing of systematic reviews and meta-analyses suggests these discussions have a meaningful influence on public perception and clinical considerations.

Abstract in brief

Omega-3 fatty acids like EPA and DHA may help reduce cardiovascular death, nonfatal heart attacks, and other heart-related events, with EPA showing slightly stronger benefits.
The study found that EPA alone might be more effective than DHA in lowering death and heart attack risks but could also increase the chance of atrial fibrillation (irregular heartbeat) and bleeding.
Overall, omega-3s seem to improve some heart health outcomes but might also carry risks like bleeding and arrhythmias, so their use should be carefully considered based on individual patient needs.]

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All mentions

High-Dose Omega-3 Fatty Acids and Heart Risk: A Study Overview

This video discusses a significant study assessing the impact of high-dose omega-3 fatty acids on cardiovascular events. The trial involved over 13,000 patients and concluded that omega-3s did not reduce the risk of…

Physionic · Jun 5, 2024 228,786 views

Omega-3 Fatty Acids and Cardiovascular Health: Benefits and Risks

Omega-3 fatty acids like EPA and DHA may help reduce cardiovascular death and heart attacks. EPA may be more effective than DHA but also carries potential risks such as atrial fibrillation and bleeding. Use should be…

Dr. Samy Mohamady الدكتور سامي محمدي · Aug 26, 2021 133,937 views

Omega-3 Fatty Acids: Impacts on Heart Health and Nutrition

Research suggests that omega-3 fatty acids may promote heart health. This video delves into the effects of increased omega-3 intake on cardiovascular events and mortality, based on a systematic review of numerous…

Naturacademy / Benjamin Dariouch · Oct 21, 2022 36,014 views

Egg Consumption and Heart Health: New Research Insights

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Thrive Nutrition RDN | Amy Lawson MS, RD, LDN · Apr 25, 2024 2,535 views

Impact of Omega-3 Fatty Acids on Heart Health Outcomes

Omega-3 fatty acids like EPA and DHA may help reduce cardiovascular death, nonfatal heart attacks, and other heart-related events. EPA shows slightly stronger benefits but may increase risks of atrial fibrillation and…

Sergey Kostyukevich · Dec 26, 2023 410 views

sybilequinox

@incelantithesis · X

@TakeThiamine You suggest omega-3s contribute to lipid peroxidation, potentially leading to cellular damage, and cite long-term accumulation as a drawback. However, a 2021 systematic review and meta-analysis in *eClinicalMedicine* (DOI: 10.1016/j.eclinm.2021.100997)

Jul 30, 2025 · 1 like · 16 followers View post →

compoundwins

@compoundwins · X

RT @compoundwins: @Faisal_Science هلا فيصل، شكراً على محتواك. فيه أكثر من ورقة علمية منشورة تشير الى احتمالية 30% زيادة العرضة بـ Atrial…

Jan 16, 2025 · 1 share · 31 followers View post →

compoundwins

@compoundwins · X

@Faisal_Science هلا فيصل، شكراً على محتواك. فيه أكثر من ورقة علمية منشورة تشير الى احتمالية 30% زيادة العرضة بـ Atrial Fibrillation (الرجفان الأذيني) مع تناول الأوميغا-3 خصوصا بجرعات عالية. وش رايك؟ 1. REDUCE-IT TRIAL 2. STRENGTH TRIAL 3. https://t.co/vf0wOrdk3q 4. https://t.co/PF8AVdP8O5

Jan 16, 2025 · 1 like · 1 share · 31 followers View post →

風地＠毎日音楽の話を(も)しています

@huuchi · X

RT @megikaya: ざっくり言うと、オメガ3は、心筋梗塞予防には効果があると考えられています。脳卒中予防にはならなそうです。うつ病の症状改善にも効果あるかもしれません。実際はもっと詳細があります。 https://t.co/3W1Oek0DFR https://…

Dec 26, 2024 · 7 shares · 1,821 followers View post →

HajimeChan

@HajimeChanChin · X

Dec 26, 2024 · 7 shares · 766 followers View post →

happy anesth

@kmyk08315265 · X

Dec 25, 2024 · 7 shares · 549 followers View post →

おれんじ色

@orangeiro7 · X

Dec 25, 2024 · 7 shares · 1,806 followers View post →

黒木玄 Gen Kuroki

@genkuroki · X

Dec 25, 2024 · 7 shares · 15,615 followers View post →

Rik@予防医療

@megikaya · X

Dec 25, 2024 · 59 likes · 7 shares · 22,210 followers View post →

Nancy Swarey

@twitbangs · X

@wbz @mallikamarshall Khan SU, et al. (2021). Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic & meta-analysis. Examines the impact of omega-3 fatty acids on cardiovascular health: #indisputable Respectfully suggest u never ever again believe ANYTHING averred by @mallikamarshall

May 29, 2024 · 2 likes · 186 followers View post →

影山　広行

@ultimumveritas · X

Lancetのオメガ３摂取に心臓血管病に対する予防効果についてもメタ解析です。 Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis 臨床医学ではNEJM、Lancet、JAMAが三大トップジャーナルです。これですべて登場しました。 https://t.co/laFKABb8Gu

Mar 9, 2024 · 956 followers View post →

Tyler Maden

@MadenTyler · X

Beneficial effects of omega-3 - Lowers risk of death - Lowers risk of heart attack - Lowers risk of CVD - Resolves inflammation - Reduced dementia risk factors - Boosts immune function - Improves gut health e.g. [https://t.co/SODOpkwMQo] (https://t.co/Kbm2B8e4Sl)

Oct 31, 2022 · 32 followers View post →

Dr Pędziwiatr

@DrPedziwiatr · X

@MlodyGrabus Aktualna duża meta analiza dotycząca Omega 3 i Ryzyka sercowo-naczyniowego. https://t.co/uXrcagFnYr

Aug 31, 2022 · 11 likes · 42 followers View post →

DMI Group - Lincoln

@dmi_lincoln · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 22, 2022 · 12 shares · 478 followers View post →

Natsir Ramadhan

@natsiradhan · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 21, 2022 · 12 shares · 557 followers View post →

DiscoStew

@DiscoStew66 · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 21, 2022 · 12 shares · 10,586 followers View post →

Claire E. Hills

@Chillslincoln79 · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 21, 2022 · 12 shares · 1,642 followers View post →

Giuseppe Biondi-Zoccai

@gbiondizoccai · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 21, 2022 · 12 shares · 12,116 followers View post →

Luiz André Almeida

@luizandr7 · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 21, 2022 · 12 shares · 202 followers View post →

Pourya Yarahmadi

@PouryaYarahmad · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 21, 2022 · 12 shares · 552 followers View post →

Mamas A. Mamas

@mmamas1973 · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 21, 2022 · 12 shares · 79,743 followers View post →

Safi U. Khan, MD, MS

@safinmc · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 21, 2022 · 12 shares · 1,187 followers View post →

Usman Shah

@cardiacshah · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 20, 2022 · 12 shares · 380 followers View post →

CardioEd Bot

@CardioBot · X

RT @AAlMohammad87: Interesting meta-analysis and systemic review @TheLancet on the effects of omega-3 fatty acids on cardiovascular mortali…

Aug 20, 2022 · 12 shares · 1,202 followers View post →

Abdallah Al-Mohammad

@AAlMohammad87 · X

Aug 20, 2022 · 25 likes · 12 shares · 924 followers View post →

Dex

@dexterizm · X

@AlpSirman "Omega-3'den fazla birşey bekleme" konusunda aksini gösteren anlamında. Sonuçta mucize bir ilaç değil, önemli ve etkili bir gıda takviyesi. Kalp damar sağlığına da bir miktar olumlu etkisini gösteren çalışmalar da var şunun gibi https://t.co/xbdDGUppBp

Jul 26, 2022 · 453 followers View post →

Sahba Ferdowsi DO (conciergedoc)

@DrFerdowsi · X

Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/V9Oyh0rAIP

Apr 2, 2022 · 9,654 followers View post →

AJ Post

@ajpost_news · X

Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/oVKnyP9CKC

Feb 14, 2022 · 10 followers View post →

د/عبدالله القرني Abdullah Algarni

@abaidalgarni · X

Hmmmmm..

Dec 28, 2021 · 2,016 followers View post →

SystematicReviewBot

@EvidenceRobot · X

RT @UPMCMercyIM: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/MSMslj1H2X

Sep 19, 2021 · 1 share · 6,718 followers View post →

UPMC Mercy Internal Medicine Residency

@UPMCMercyIM · X

Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/MSMslj1H2X

Sep 19, 2021 · 1 like · 1 share · 3,105 followers View post →

Michael Fahem

@Michael_maher50 · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

Sep 16, 2021 · 13 shares · 936 followers View post →

Gustavo Aurelian0

@GustavoGHLA · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

Sep 13, 2021 · 13 shares · 11 followers View post →

gizigama

@gizigama · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

Sep 13, 2021 · 13 shares · 21 followers View post →

Maricruz Espinosa.

@mespinoosap · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

Sep 12, 2021 · 13 shares · 72 followers View post →

Weldon

@Rocker75W · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

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Renato Dumbra

@renatodumbra · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

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Alex

@AlexViKu · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

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Dani Reyes Olavarría

@Daniitota · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

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Jose

@Jose_8523 · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

Sep 12, 2021 · 13 shares · 294 followers View post →

Jose Antonio PhD

@JoseAntonioPhD · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

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PT_Thunem

@PT_Thunem · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

Sep 12, 2021 · 13 shares · 80 followers View post →

Raj Makhija

@iRajMakhija · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

Sep 12, 2021 · 13 shares · 1,943 followers View post →

OJSN

@iamojsn · X

RT @ExphysPhD: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Omega-3 FAs reduced cardiov…

Sep 12, 2021 · 13 shares · 14,998 followers View post →

Jeffrey R. Stout

@ExphysPhD · X

Sep 12, 2021 · 47 likes · 13 shares · 3,517 followers View post →

Alan Watson

@Alan_Watson_ · X

@NutritionMadeS3 @ScepticalDoctor Questions have increasingly been asked about the possible disbenefits of DHA (LDL raising etc) recent publications confirm that it could be better to consider EPA rather than EPA+DHA given the significant greater benefits from EPA alone eg: 10.1016/j.eclinm.2021.100997 https://t.co/cQ0a1SbHMv

Sep 2, 2021 · 1 like · 1,474 followers View post →

PF Anderson @pfanderson@disabled.social

@pfanderson · X

Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/DeWgTkJM7c #sysrev

Jul 21, 2021 · 10,792 followers View post →

Reiner 

@erlesen · X

RT @erlesen: Purified ethyl ester of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have had mixed results https://t.co/o7hyrp…

Jul 14, 2021 · 2 shares · 7,847 followers View post →

Dr Shraboni Ghosal, PhD

@ShraboniGhosal · X

RT @erlesen: Purified ethyl ester of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have had mixed results https://t.co/o7hyrp…

Jul 14, 2021 · 2 shares · 1,929 followers View post →

ScienceStop

@B0tSci · X

RT @Dra_TeraizaMesa: RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3…

Jul 13, 2021 · 5 shares · 4,081 followers View post →

Lee

@greeneyedlizzie · X

RT @Dra_TeraizaMesa: RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3…

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Atanas G. Atanasov

@_atanas_ · X

RT @Dra_TeraizaMesa: RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3…

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Science Communication

@ScienceCommuni2 · X

RT @dronita_de: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/6uOmFL4Wga

Jul 13, 2021 · 2 shares · 2,870 followers View post →

Atanas G. Atanasov

@_atanas_ · X

RT @dronita_de: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/6uOmFL4Wga

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Science Communication

@ScienceCommuni2 · X

RT @Dra_TeraizaMesa: RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3…

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International Natural Product Sciences Taskforce

@_INPST · X

RT @Dra_TeraizaMesa: RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3…

Jul 12, 2021 · 5 shares · 10,256 followers View post →

Reiner 

@erlesen · X

Purified ethyl ester of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have had mixed results https://t.co/o7hyrpQT7l Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. Published: July 08, 2021 https://t.co/JITx55h3m1

Jul 12, 2021 · 4 likes · 2 shares · 7,847 followers View post →

Dra. Teraiza Mesa R Cuenta Oficial ®

@Dra_TeraizaMesa · X

Jul 12, 2021 · 9 likes · 5 shares · 9,091 followers View post →

Vital Vitamins

@myvitalvitamins · X

Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis - The Lancet https://t.co/0gs55LBR9t

Jul 12, 2021 · 32 followers View post →

Joaquín San José

@jsanjosea · X

RT @nick_krontiris: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis (open access) https://…

Jul 12, 2021 · 1 share · 409 followers View post →

Dr Shraboni Ghosal, PhD

@ShraboniGhosal · X

RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

Jul 12, 2021 · 21 shares · 1,929 followers View post →

Nick Krontiris

@nick_krontiris · X

Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis (open access) https://t.co/Tv8aTWP7e6 #nutrition #diet #supplement #supplements #Omega3 #PUFAs

Jul 12, 2021 · 2 likes · 1 share · 18,972 followers View post →

Ronita De, PhD

@dronita_de · X

Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/6uOmFL4Wga

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Ronita De, PhD

@dronita_de · X

RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

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@TheBhupiThakur · X

RT @LSchwingshackl: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/lQDaspM6xk

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Lukas Schwingshackl

@LSchwingshackl · X

Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/lQDaspM6xk

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@ZarudinMS · X

RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

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ScienceStop

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RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

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Atanas G. Atanasov

@_atanas_ · X

RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

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Nattha Saravutanukul

@n3nnnnn · X

RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

Jul 11, 2021 · 21 shares · 368 followers View post →

RealRositaFonseca

@CalifQuail1969 · X

RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

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Lee

@greeneyedlizzie · X

RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

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BIKRAMJIT KONWAR

@YogaOfFreedom · X

RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

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RT @evanbeloff: “Omega-3 FAs reduced cardiovascular mortality & improved cardiovascular outcomes. cardiovascular risk reduction was more pr…

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Alison L. Bailey, MD

@a_l_bailey · X

RT @drpablocorral:

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Evan Beloff

@evanbeloff · X

“Omega-3 FAs reduced cardiovascular mortality & improved cardiovascular outcomes. cardiovascular risk reduction was more prominent with EPA than with EPA+DHA”. Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review & meta-analysis https://t.co/mk1zxSgVjz

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RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

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RT @_atanas_: Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis #Omega3 #FattyAcids #Cardiov…

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Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/txCnumLWH6

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Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis https://t.co/Jm2f4NFmXI

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Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis.

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