Genome Med September 2021 PMID 34517888

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis.

Vinod K Gupta, Kevin Y Cunningham, Benjamin Hur, Utpal Bakshi, Harvey Huang, Kenneth J Warrington, Veena Taneja, Elena Myasoedova, John M Davis, Jaeyun Sung

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Mentions

71
Peak: 16 in Sep 2021
across 4 sources since Sep 2021

Extended reach

177,854
potential audience

Total likes

134

Video views

2,994

Mentions per month

Sep 2021 – Sep 2023

Where it's discussed

  • News36 articles
  • X / Twitter28 posts
  • Blogs4 articles
  • YouTube3 videos

AI synopsis

What people are saying

The overall tone suggests high enthusiasm for the study, as seen in posts calling it a 'big step' and highlighting the use of advanced techniques like machine learning, indicating that these discussions see microbiome research as having a transformative impact on understanding and managing rheumatoid arthritis.

AgreementStrong agreement

Most discussions express strong agreement with the findings, highlighting the significance of microbiome research in RA prognosis.

InterestHigh interest

Posts demonstrate high interest, emphasizing the complex links and promising predictive capabilities, using phrases like 'big step' and 'significant indicator'.

EngagementHigh engagement

Many posts reference specific methods, such as metagenome sequencing and AI predictions, indicating deep engagement with the research details.

ImpactHigh impact

The discussions underscore the potential for microbiome analysis to transform RA diagnosis and treatment, calling it a 'game changer' and a 'non-invasive tool'.

Abstract in brief

  • The study investigates how gut microbiome features relate to clinical improvement in rheumatoid arthritis (RA), aiming to identify microbial indicators that predict whether patients will experience meaningful disease improvement.
  • Researchers analyzed stool samples from RA patients over time, using advanced sequencing and machine learning to link gut bacteria and biochemical pathways with patient outcomes, finding age and microbiome composition as significant factors.
  • The findings suggest that certain baseline gut microbiome traits are associated with future clinical improvement, highlighting the gut microbiome's potential role in predicting and possibly influencing RA treatment responses.

Top posts

Most liked on X and Bluesky
Jaeyun Sung, PhD
@jsung0906 · X

Sharing our latest work with #MayoClinicRheumatology @JohnDavisIII @MdWarrington @MyasoedovaElena showing that a significant indicator of whether a patient with #RheumatoidArthritis will improve over the course of disease may lie in part in the gut!

Sep 13, 2021 · 18 likes · 5 shares · 323 followers View post →
Biocodex Microbiota Institute
@Microbiota_Inst · X

A new study in @BioMedCentral: "Gut microbial determinants of clinically important improvement in patients with #RheumatoidArthritis." #GutMicrobiota @vinodgupta299 @VeenaTaneja @MyasoedovaElena @JohnDavisIII @jsung0906 @MayoClinic

Sep 17, 2021 · 6 likes · 1 share · 26,840 followers View post →
Massimo Barberi
@masbarberi · X

Researchers at the Mayo Clinic used gut microbiome data and artificial intelligence to predict clinical outcomes of rheumatoid arthritis with an accuracy of 90% | Genome Medicine | Full Text https://t.co/weu9V7uhoV

Oct 19, 2021 · 6 likes · 2 shares · 3,823 followers View post →
Joe Blair
@joefromlondon · X

As I discovered in my PhD, RA is seriously complex. New findings showing links between Clinical improvement and the microbiome is surely a big step! #Bioinformatics #autoimmune #microbiome #Genetics https://t.co/Mbs9wcMTHM

Nov 6, 2021 · 4 likes · 3 shares · 300 followers View post →
XiaoTao JIANG
@Titus12629950 · X

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis from @jaeyunsun #RheumatoidArthritis @GenomeMedicine #arthritis https://t.co/NWZ24ZMrz8 https://t.co/dvcGGAw2sE

Oct 16, 2021 · 3 likes · 1 share · 371 followers View post →
BMC
@BioMedCentral · X

A study published in @GenomeMedicine found that the gut microbiome could be used as a non-invasive tool for predicting clinical improvement and for monitoring rheumatoid arthritis activity. https://t.co/K1wMphffOM

Sep 15, 2021 · 2 likes · 1 share · 75,404 followers View post →

All mentions

François Booream
@BooraemFrancois · X

ra is similar pathways per uc/crohns. relates to gut permeability issues as well. https://t.co/sfzSFICMZH https://t.co/DULZ2FsGpx

Mar 25, 2022 · 725 followers View post →
Altamiro Bottino
@BottinoAltamiro · X

Researchers link gut microbiome to rheumatoid arthritis prognosis https://t.co/BNdJ49nI6K https://t.co/OI2iavCuQR https://t.co/CeZw1AC8i4

Nov 30, 2021 · 93 followers View post →
ALI MUHAMMED ~
@BinMohammed07 · X

Further Reading; ''A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery'' https://t.co/RTUt26PzG8 ''Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis'' https://t.co/nIJZR50gDU https://t.co/KZoK49gzFg

Nov 16, 2021 · 2,332 followers View post →
Bioinformatics Trends 
@BinfoTrends · X

RT @joefromlondon: As I discovered in my PhD, RA is seriously complex. New findings showing links between Clinical improvement and the micr…

Nov 6, 2021 · 3 shares · 8,157 followers View post →
CompChemBio Bot
@CompChemBioBot · X

RT @joefromlondon: As I discovered in my PhD, RA is seriously complex. New findings showing links between Clinical improvement and the micr…

Nov 6, 2021 · 3 shares · 2,762 followers View post →
Joe Blair
@joefromlondon · X

As I discovered in my PhD, RA is seriously complex. New findings showing links between Clinical improvement and the microbiome is surely a big step! #Bioinformatics #autoimmune #microbiome #Genetics https://t.co/Mbs9wcMTHM

Nov 6, 2021 · 4 likes · 3 shares · 300 followers View post →
AIT RAHOU Omar
@AITRAHOUOmar1 · X

RT @masbarberi: Researchers at the Mayo Clinic used gut microbiome data and artificial intelligence to predict clinical outcomes of rheumat…

Oct 20, 2021 · 2 shares · 352 followers View post →
Kumar Sankaran
@BiomeSankar · X

RT @masbarberi: Researchers at the Mayo Clinic used gut microbiome data and artificial intelligence to predict clinical outcomes of rheumat…

Oct 19, 2021 · 2 shares · 813 followers View post →
Massimo Barberi
@masbarberi · X

Researchers at the Mayo Clinic used gut microbiome data and artificial intelligence to predict clinical outcomes of rheumatoid arthritis with an accuracy of 90% | Genome Medicine | Full Text https://t.co/weu9V7uhoV

Oct 19, 2021 · 6 likes · 2 shares · 3,823 followers View post →
Emad El-Omar
@emadelomar · X

RT @Titus12629950: Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis from @jaeyunsun #Rh…

Oct 17, 2021 · 1 share · 3,876 followers View post →
XiaoTao JIANG
@Titus12629950 · X

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis from @jaeyunsun #RheumatoidArthritis @GenomeMedicine #arthritis https://t.co/NWZ24ZMrz8 https://t.co/dvcGGAw2sE

Oct 16, 2021 · 3 likes · 1 share · 371 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@SueBrownSB The immune system is influenced by the microbiome, a network of microorganisms that live in and on the human body. These microbes outnumber the body’s cells by 10 to 1. Trillions of microbes — both helpful and harmful — reside in the digestive tract.

Oct 1, 2021 · 373 followers View post →
NANNO
@HiSoKa30M · X

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis | Genome Medicine https://t.co/wfIoI47Aqs

Sep 21, 2021 · 81 followers View post →
GutMicrobiomePapers
@GutPapers · X

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis https://t.co/cXlURVquRg

Sep 18, 2021 · 1 like · 518 followers View post →
John M. Davis III, MD MS
@JohnDavisIII · X

RT @Microbiota_Inst: A new study in @BioMedCentral: "Gut microbial determinants of clinically important improvement in patients with #Rheum…

Sep 17, 2021 · 1 share · 1,123 followers View post →
Biocodex Microbiota Institute
@Microbiota_Inst · X

A new study in @BioMedCentral: "Gut microbial determinants of clinically important improvement in patients with #RheumatoidArthritis." #GutMicrobiota @vinodgupta299 @VeenaTaneja @MyasoedovaElena @JohnDavisIII @jsung0906 @MayoClinic

Sep 17, 2021 · 6 likes · 1 share · 26,840 followers View post →
Dr. John Cush
@RheumNow · X

32 RA pts; each w/ 2 stool samples >6 mos apart - stool metagenome sequencing stool samples and pt activity assessed. Microbiome most influenced by age, followed by those achieving minimum clinically important improvement https://t.co/unaEOOuP34

Sep 17, 2021 · 1 like · 24,538 followers View post →
BMC Biology
@BMCBiology · X

RT @BioMedCentral: A study published in @GenomeMedicine found that the gut microbiome could be used as a non-invasive tool for predicting c…

Sep 15, 2021 · 1 share · 9,020 followers View post →
BMC
@BioMedCentral · X

A study published in @GenomeMedicine found that the gut microbiome could be used as a non-invasive tool for predicting clinical improvement and for monitoring rheumatoid arthritis activity. https://t.co/K1wMphffOM

Sep 15, 2021 · 2 likes · 1 share · 75,404 followers View post →
Dr Anthony Martin
@AMAinsight · X

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis | Genome Medicine | Full Text https://t.co/rWFedfepWd

Sep 15, 2021 · 913 followers View post →
Elena MyasoedovaMD ☀️
@MyasoedovaElena · X

RT @jsung0906: Sharing our latest work with #MayoClinicRheumatology @JohnDavisIII @MdWarrington @MyasoedovaElena showing that a significant…

Sep 14, 2021 · 5 shares · 880 followers View post →
Metagenomics Papers
@metagenomic_lit · X

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis https://t.co/Uu0V43IUjf

Sep 14, 2021 · 3,702 followers View post →
Symbiosis papers
@Symbiosispapers · X

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis https://t.co/qNe7AsCQV8

Sep 14, 2021 · 1,114 followers View post →
KenWarringtonMD
@MdWarrington · X

RT @jsung0906: Sharing our latest work with #MayoClinicRheumatology @JohnDavisIII @MdWarrington @MyasoedovaElena showing that a significant…

Sep 14, 2021 · 5 shares · 3,710 followers View post →
Anupam Gautam
@Anupam__Gautam · X

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis https://t.co/wH4pZfHnwp

Sep 14, 2021 · 125 followers View post →
John M. Davis III, MD MS
@JohnDavisIII · X

RT @jsung0906: Sharing our latest work with #MayoClinicRheumatology @JohnDavisIII @MdWarrington @MyasoedovaElena showing that a significant…

Sep 13, 2021 · 5 shares · 1,123 followers View post →
Kazuhiro Takemoto
@kztakemoto · X

RT @jsung0906: Sharing our latest work with #MayoClinicRheumatology @JohnDavisIII @MdWarrington @MyasoedovaElena showing that a significant…

Sep 13, 2021 · 5 shares · 1,377 followers View post →
Jaeyun Sung, PhD
@jsung0906 · X

Sharing our latest work with #MayoClinicRheumatology @JohnDavisIII @MdWarrington @MyasoedovaElena showing that a significant indicator of whether a patient with #RheumatoidArthritis will improve over the course of disease may lie in part in the gut!

Sep 13, 2021 · 18 likes · 5 shares · 323 followers View post →