October 2021 PMID 34535961

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA study.

Giovanni Fiorito, Saverio Caini, Domenico Palli, Benedetta Bendinelli, Calogero Saieva, Ilaria Ermini, Virginia Valentini, Melania Assedi, Piera Rizzolo, Daniela Ambrogetti, Laura Ottini, Giovanna Masala

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Mentions

139
Peak: 99 in Sep 2021
across 6 sources since Sep 2021

Extended reach

681,076
potential audience

Total likes

12,122

Video views

251,096

Mentions per month

Sep 2021 – Aug 2024

Where it's discussed

  • X / Twitter123 posts
  • News5 articles
  • Blogs4 articles
  • YouTube3 videos
  • Facebook2 posts
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AI synopsis

What people are saying

Several discussions highlight the study's results, emphasizing how lifestyle changes positively impacted DNA methylation markers of aging. Comments like 'evidence of a causal association between lifestyle modification and slowing down DNAm aging biomarkers' reflect a deeper analysis of this research. The tone is generally positive, with users eagerly engaging in questions about how different diets might influence health, indicating a strong interest and the potential impact on personal health choices.

AgreementModerate agreement

Many discussions support the findings of the published study, indicating a consensus on the benefits of lifestyle interventions.

InterestHigh interest

A significant number of participants express curiosity about the implications of the study and how it relates to existing knowledge of diet and exercise.

EngagementModerate engagement

While some posts agree or mention the study's findings, others delve into specific aspects like the relationship between certain foods and biological aging.

ImpactHigh impact

There is a strong belief that the study will influence future research and public health guidelines regarding diet and physical activity.

Abstract in brief

  • A two-year study (DAMA) investigated the impact of diet and physical activity on DNA methylation-based aging biomarkers in postmenopausal women.
  • Improved dietary habits significantly slowed the DNAmGrimAge clock, an advanced predictor of biological age and longevity.
  • Increased physical activity led to a notable reduction in stochastic epigenetic mutations, supporting a link between lifestyle changes and healthier aging markers.

Top posts

Most liked on X and Bluesky
Aging Science News
@AgingBiology · X

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA study https://t.co/iCCv74xIEC

Sep 26, 2021 · 45 likes · 5 shares · 30,594 followers View post →
Agingdoc
@agingdoc1 · X

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA study (2021) "... evidence of a causal association between lifestyle modification and slowing down of DNAm aging biomarkers." https://t.co/u7E2PN7JV2 https://t.co/SrdAVjFcFZ

Jan 6, 2023 · 28 likes · 11 shares · 41,667 followers View post →
Bruno Vellas
@brunovellas · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study - Fiorito - - Aging Cell - Wiley Online Library https://t.co/NQodK61qkS

Sep 22, 2021 · 13 likes · 10 shares · 2,563 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study https://t.co/lJaWAa6PXy

Sep 19, 2021 · 8 likes · 3 shares · 9,722 followers View post →
Alexander Boldizar
@Boldizar · X

@PeterAttiaMD Yes! This has been my biggest question since you had Rick Johnson on! How do we reconcile fructose negatives with studies like this where only fruit had p-value below 0.05 (table 2) for helping bio aging. I'm keto otherwise, but love all fruit. https://t.co/xOO66uUTu9

Jan 13, 2022 · 3 likes · 2,459 followers View post →
Juan C. Opazo
@opazolab · X

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA study https://t.co/iDIidFqEtk

Sep 22, 2021 · 3 likes · 1 share · 1,667 followers View post →

All mentions

Impact of Diet and Exercise on Biological Aging

This video explores recent research on how diet and physical activity can reverse biological aging. It reviews a two-year study showing that improved dietary habits and increased physical activity significantly slowed…

Lift'N'Balance · Oct 14, 2021 407 views
Abhishek Singh
@tremblerz · X

@icepick1001 @GaryMarcus In addition to the below, you can find plenty of studies showing the impact of lifestyle interventions (exercise, diet, etc.) on all-cause mortality risk https://t.co/uJsInswYUs https://t.co/DE1NHpBIbs https://t.co/bhKTsVh467

Sep 4, 2023 · 639 followers View post →
JCM Compounding Knowledge
@JCM_IF · X

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA study https://t.co/r6rRRBXJeC

Jun 21, 2023 · 3,933 followers View post →
roosgar
@roosgarvi · X

https://t.co/nd4KB1Q5dr

Jan 18, 2023 · 1,204 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 12, 2023 · 11 shares · 132 followers View post →
행님(동결중)
@20new00 · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 8, 2023 · 11 shares · 123 followers View post →
구독계A
@gdgd1004gd · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 7, 2023 · 11 shares · 24 followers View post →
Alis volat propriis
@Alisvolatprop12 · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 7, 2023 · 11 shares · 19,535 followers View post →
Heewon Jung
@DrEcsta · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 7, 2023 · 11 shares · 128,854 followers View post →
Dr. Chris Chappel
@ChappelDr · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 7, 2023 · 11 shares · 13,618 followers View post →
Science
@Long_life_sci · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 6, 2023 · 11 shares · 33 followers View post →
KALLEL Labs
@labs_sir · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 6, 2023 · 11 shares · 115 followers View post →
Saturnsky, MBA, BigTech Exec Corporate Demon
@mba_big · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 6, 2023 · 11 shares · 236 followers View post →
Dr. Rajesh Jain, MD
@DiabetesAsiaOrg · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 6, 2023 · 11 shares · 1,674 followers View post →
Fay
@fay90028966 · X

RT @agingdoc1: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the…

Jan 6, 2023 · 11 shares · 142 followers View post →
Agingdoc
@agingdoc1 · X

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA study (2021) "... evidence of a causal association between lifestyle modification and slowing down of DNAm aging biomarkers." https://t.co/u7E2PN7JV2 https://t.co/SrdAVjFcFZ

Jan 6, 2023 · 28 likes · 11 shares · 41,667 followers View post →
АлексейБойко
@baykaji777 · X

https://t.co/057YlUBJsQ

Oct 30, 2022 · 28 followers View post →
Alice Medeiros
@alicevmedeiros · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study https://t.co/ZmnSTSxkCh

Jul 26, 2022 · 152 followers View post →
Lincoln Cannon
@LincolnCannon · X

RT @thrivous: Improved diet and increased physical activity have favorable effects on epigenetic biomarkers of aging. Lab animal testing of…

Mar 15, 2022 · 2 shares · 7,199 followers View post →
Lincoln Cannon LLC
@lincolncannonco · X

RT @thrivous: Improved diet and increased physical activity have favorable effects on epigenetic biomarkers of aging. Lab animal testing of…

Mar 6, 2022 · 2 shares · 1,355 followers View post →
Thrivous
@thrivous · X

Improved diet and increased physical activity have favorable effects on epigenetic biomarkers of aging. Lab animal testing of longevity consequences is underway to confirm the practical ramifications. https://t.co/AwY911ZxgB

Mar 6, 2022 · 2 likes · 2 shares · 11,791 followers View post →
Alexander Boldizar
@Boldizar · X

@PeterAttiaMD Yes! This has been my biggest question since you had Rick Johnson on! How do we reconcile fructose negatives with studies like this where only fruit had p-value below 0.05 (table 2) for helping bio aging. I'm keto otherwise, but love all fruit. https://t.co/xOO66uUTu9

Jan 13, 2022 · 3 likes · 2,459 followers View post →
Alexander Boldizar
@Boldizar · X

@PeterAttiaMD Fruit, please! Ep #87: “It’s not as bad as other sugar because of fiber & volume.” But lots of studies show fruit is not just neutral, but positive. https://t.co/xOO66uUTu9 I’m keto + fruit & can’t reconcile fructose ideas with overall health advantages of eating fruit. Thx

Nov 22, 2021 · 2,459 followers View post →
ENDALA klinika zdraví
@endalaclinic · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study - Fiorito - 2021 - Aging Cell - Wiley Online Library https://t.co/fTdKd4B6mA

Nov 9, 2021 · 1 like · 253 followers View post →
TruDiagnostic
@TruDiagnostic · X

A 2 year trial on Diet and Exercise of post-menopausal women found that easily-achievable changes to lifestyle successfully slowed aging, measured by the GrimAge epigenetic clock. Discover the study here https://t.co/1P8bvFnSkl https://t.co/vflIgosjkt

Oct 28, 2021 · 1 like · 1,337 followers View post →
Orlando_uy
@Orlando_uy · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study https://t.co/6aXbSi4Uls

Sep 30, 2021 · 2 likes · 694 followers View post →
Nikki Noren Hooten
@nnhooten · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study https://t.co/uEyAtfIzIH

Sep 27, 2021 · 2 likes · 1,320 followers View post →
Ryan Bailey
@BioExplorr · X

RT @AgingBiology: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: t…

Sep 26, 2021 · 5 shares · 195 followers View post →
Carl Sordoni
@sordo44 · X

RT @AgingBiology: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: t…

Sep 26, 2021 · 5 shares · 529 followers View post →
Alexander Dakhovnik
@ADakhovnik · X

RT @AgingBiology: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: t…

Sep 26, 2021 · 5 shares · 77 followers View post →
Healthspan
@HealthspanBot · X

#FightAging #EndAging #Lifespan #Healthspan https://t.co/MwIedgwCdT

Sep 26, 2021 · 51 followers View post →
Fay
@fay90028966 · X

RT @AgingBiology: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: t…

Sep 26, 2021 · 5 shares · 142 followers View post →
The Phoenix Lab
@The_Phoenix_Lab · X

RT @AgingBiology: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: t…

Sep 26, 2021 · 5 shares · 210 followers View post →
Aging Science News
@AgingBiology · X

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA study https://t.co/iCCv74xIEC

Sep 26, 2021 · 45 likes · 5 shares · 30,594 followers View post →
Longevity Wiki
@longevitywiki · X

RT @longevitywiki: Now, Could A Mediterranean Diet, Make Us Live Longer?

Sep 25, 2021 · 2 shares · 554 followers View post →
ProfSAldred
@DrSAldred · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study https://t.co/TBUb9KCpr6

Sep 23, 2021 · 253 followers View post →
INSPIRE Platform - IHU HealthAge
@INSPIREPlatfor1 · X

RT @brunovellas: DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: th…

Sep 23, 2021 · 10 shares · 674 followers View post →
Osteoporosis-NL @osteoporosis-nl.bsky.social
@Osteoporosis_NL · X

DNA methylation-based biomarkers of aging were slowed down in a 2-yr diet and physical activity intervention trial: the DAMA study. G Fiorito et al. Aging Cell 18 Sept 2021 https://t.co/dCMyKxmHix causal relationship between lifestyle and healthy aging-related epigenetics

Sep 23, 2021 · 1 like · 3,382 followers View post →
APalacio_s
@APalacio_s · X

RT @opazolab: DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the D…

Sep 22, 2021 · 1 share · 1,873 followers View post →
Terri Haber
@TerriCHaber · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study - Fiorito - - Aging Cell - Wiley Online Library https://t.co/yzbKWWW1xt

Sep 22, 2021 · 55 followers View post →
Dr. Neil Paulvin
@NeilpDo · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study https://t.co/aUyWuu13aK - via Researcher (@ResearcherApp) https://t.co/knROr0eIBr

Sep 22, 2021 · 1 like · 2,844 followers View post →
Kathy Hubbell
@itsokhub · X

RT @davidasinclair: Aging news: Abundance of a chemical called a DNA-methyl represents biological age

Sep 22, 2021 · 288 shares · 34 followers View post →
Shamelessly Marketing African Books
@AbdullahiBulle · X

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Sep 22, 2021 · 288 shares · 3,188 followers View post →
Pauline
@Poplinecreation · X

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Sep 22, 2021 · 288 shares · 285 followers View post →
2140wtf
@2140wtf · X

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Sep 22, 2021 · 288 shares · 1,428 followers View post →
Mike
@Mike_riss · X

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Sep 22, 2021 · 288 shares · 112 followers View post →
YodaVerse
@yoda_money · X

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Melchior
@melchior_b · X

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HL
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nhove
@NHovemann · X

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Juan Gargiulo
@jmgargiulo · X

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Sep 22, 2021 · 288 shares · 211 followers View post →
MAshraf
@MinaalAshraf · X

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Symon
@symonlistens · X

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Sep 22, 2021 · 288 shares · 84 followers View post →
Moiz Masood Sultani
@Moiz · X

RT @davidasinclair: Aging news: Abundance of a chemical called a DNA-methyl represents biological age

Sep 22, 2021 · 288 shares · 2,522 followers View post →
Jon
@xujun_jon · X

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CK
@CKitsakis · X

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Sep 22, 2021 · 288 shares · 437 followers View post →
Drew Richard
@drewrgraphics · X

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Sep 22, 2021 · 288 shares · 111 followers View post →
Bertram Eyakuze
@beyakuze · X

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Sep 22, 2021 · 288 shares · 208 followers View post →
Robert Havercroft
@RHHealthyLiving · X

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Sep 22, 2021 · 288 shares · 28 followers View post →
|Truth | Clarity | High signal
@gkosfra · X

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Sep 22, 2021 · 288 shares · 57 followers View post →
Longevity
@longevitymag · X

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emilio cardenal (v3)
@emilio_cardenal · X

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Sep 22, 2021 · 288 shares · 310 followers View post →
Elizabeth Blakemore
@Eliza_Blakemore · X

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Naftali Shangala
@Easynaf2022 · X

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Sep 22, 2021 · 288 shares · 1,700 followers View post →
Magda Purizaca
@MagdaPurizaca1 · X

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Sep 22, 2021 · 288 shares · 30 followers View post →
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@Aaron8Parker · X

RT @davidasinclair: Aging news: Abundance of a chemical called a DNA-methyl represents biological age

Sep 22, 2021 · 288 shares · 502 followers View post →
PetriBio_edu
@1000yrlifespan · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study https://t.co/rKoGNILIDr

Sep 22, 2021 · 67 followers View post →
biotechcool
@ro_portu · X

RT @davidasinclair: Aging news: Abundance of a chemical called a DNA-methyl represents biological age

Sep 22, 2021 · 288 shares · 123 followers View post →
PetriBio_edu
@1000yrlifespan · X

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Muzzpol
@Muzzpol · X

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Sep 22, 2021 · 288 shares · 861 followers View post →
Kashif Ansari
@ansarikashif7 · X

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Sep 22, 2021 · 288 shares · 741 followers View post →
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@dut_c_h · X

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Arthur Bartoli - e/acc
@MorganArthur13_ · X

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@fundix2 · X

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@Pao_23 · X

RT @davidasinclair: Aging news: Abundance of a chemical called a DNA-methyl represents biological age

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Gregory Pokrywka MD FACP FNLA FASPC NCMP
@gpokmd · X

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@twoblackparents · X

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Jabez Consulting
@jabezconsulting · X

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The Phoenix Lab
@The_Phoenix_Lab · X

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Sep 22, 2021 · 288 shares · 210 followers View post →
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@kudaclaver · X

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Sep 22, 2021 · 288 shares · 291 followers View post →
Dr. Marozau Aliaksandr/FutureCollector
@MisterioMoRoZ · X

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Sep 22, 2021 · 288 shares · 207 followers View post →
Hussain
@bayogah · X

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Sep 22, 2021 · 288 shares · 167 followers View post →
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@julemindbody · X

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Sep 22, 2021 · 288 shares · 499 followers View post →
ICFSRcongress
@ICFSRcongress · X

RT @brunovellas: DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: th…

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JFA
@JFrailtyAging · X

RT @brunovellas: DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: th…

Sep 22, 2021 · 10 shares · 3,509 followers View post →
The Journal of Nutrition, Health & Aging
@JNHA6 · X

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@jpreventionalz1 · X

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Investment Frog
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@vadimX_ · X

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@HilaryKernMD · X

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@mst4truth · X

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Longevity Wiki
@longevitywiki · X

Now, Could A Mediterranean Diet, Make Us Live Longer?

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Veeragopal kamarapu
@veeragopalk · X

RT @davidasinclair: Aging news: Abundance of a chemical called a DNA-methyl represents biological age

Sep 22, 2021 · 288 shares · 174 followers View post →
Serg
@__DigitalBath__ · X

RT @davidasinclair: Aging news: Abundance of a chemical called a DNA-methyl represents biological age

Sep 22, 2021 · 288 shares · 61 followers View post →
Scott Penberthy
@scottpenberthy · X

RT @davidasinclair: Aging news: Abundance of a chemical called a DNA-methyl represents biological age

Sep 22, 2021 · 288 shares · 1,603 followers View post →
Johns Hopkins Frailty Science #FrailtyFighter
@FrailtyScience · X

RT @brunovellas: DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: th…

Sep 22, 2021 · 10 shares · 2,270 followers View post →
Emel Taş
@EmelieTas · X

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA study @Wileyonline https://t.co/UStGhiTrcj

Sep 22, 2021 · 99 followers View post →
Juan C. Opazo
@opazolab · X

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA study https://t.co/iDIidFqEtk

Sep 22, 2021 · 3 likes · 1 share · 1,667 followers View post →
Ivan Aprahamian
@IAprahamian · X

RT @brunovellas: DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: th…

Sep 22, 2021 · 10 shares · 489 followers View post →
Bruno Vellas
@brunovellas · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study - Fiorito - - Aging Cell - Wiley Online Library https://t.co/NQodK61qkS

Sep 22, 2021 · 13 likes · 10 shares · 2,563 followers View post →
Ken Gusler
@kgusler · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: https://t.co/LZm56Rpnd0

Sep 20, 2021 · 20,030 followers View post →
Rapamycin News
@RapaNews · X

RT @mike_lustgarten: DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial…

Sep 19, 2021 · 3 shares · 5,312 followers View post →
Muzzpol
@Muzzpol · X

RT @mike_lustgarten: DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial…

Sep 19, 2021 · 3 shares · 861 followers View post →
AntiAgify - Science will set you free
@AntiAgify · X

RT @mike_lustgarten: DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial…

Sep 19, 2021 · 3 shares · 1,352 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study https://t.co/lJaWAa6PXy

Sep 19, 2021 · 8 likes · 3 shares · 9,722 followers View post →
Nutriop Longevity
@nutriop · X

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity intervention trial: the DAMA... https://t.co/DZVggG4c7R

Sep 19, 2021 · 80 followers View post →
Società Italiana di Gerontologia e Geriatria
@GeriSocITA · X

DNA methylation-based biomarkers of aging were slowed down in a two-year diet and physical activity int...: https://t.co/xEX3GP3LN5

Sep 19, 2021 · 725 followers View post →