Mol Autism September 2021 PMID 34537069

Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis.

Stephanie Antoun, Pierre Ellul, Hugo Peyre, Michelle Rosenzwajg, Pierre Gressens, David Klatzmann, Richard Delorme

Mentions

67
Peak: 21 in Sep 2025
across 5 sources since Sep 2021

Extended reach

232,576
potential audience

Total likes

9,673

Video views

77,330

Mentions per month

Sep 2021 – Oct 2025

Where it's discussed

  • X / Twitter30 posts
  • News26 articles
  • Bluesky6 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect a generally supportive stance towards the study, with posts like '@AshleyGWinter Do they know untreated maternal fever is bad for foetal brain tissue?' showing concern, and references to the study's statistical findings, such as an increased odds ratio for neurodevelopmental disorders. The tone varies from curiosity and concern to critique of misinformation, illustrating an engaged audience considering both scientific and societal implications.

AgreementModerate agreement

Most discussions accept the findings that maternal fever is associated with increased neurodevelopmental risks, with some emphasizing the importance of awareness and precaution.

InterestHigh interest

Posts express high curiosity and concern about the implications, with many sharing personal opinions or rhetorical questions about the significance of the study.

EngagementModerate engagement

Several discussions delve into implications for pregnant women, referencing mechanisms, treatments, and societal reactions, indicating moderate engagement.

ImpactModerate impact

The discussions aim to influence perceptions about managing maternal fever and highlight potential policy or health recommendations, indicating a moderate impact.

Abstract in brief

  • The systematic review and meta-analysis found that maternal fever during pregnancy is associated with a higher risk of neurodevelopmental disorders (NDD) in children, with an overall odds ratio of 1.24, especially when fever occurs during the first trimester.
  • The study included ten research studies totaling over 10,000 children, of which about 1,394 were exposed to maternal fever, and highlighted that fever severity, duration, and factors like medication use and timing during pregnancy can influence this risk.
  • Limitations noted in the analysis include heterogeneity among the different studies and the exclusion of research focusing solely on infections without fever, which suggests that more research is needed to clarify these factors fully.

Top posts

Most liked on X and Bluesky
Dr Katie Cairns
@kiityc · X

@AshleyGWinter Do they know untreated maternal fever is bad for foetal brain tissue? People take Tylenol to treat pain and fever. It may be the fever, not the drug. Influenza and Covid cause fever…and he wants to ban those vaccines. https://t.co/SaBI2z18mh https://t.co/gFCFegmaLA

Sep 6, 2025 · 13 likes · 3 shares · 3,105 followers View post →
Thiago Roitman
@thiagomelo.bsky.social · Bluesky

Queria muito ser presidente pra poder virar pra Laura e dizer: DEIXA EU COLOCAR ESSE VÍDEO EM REDE NACIONAL NO INTERVALO DA NOVELA OU NA FINAL DO CAMPEONATO BRASILEIRO??? youtu.be/8M_WWkT99P8?...

Sep 30, 2025 · 10 likes · 2 shares View post →
N of One
@NofOneAutism · X

FEVER DURING PREGNANCY seems to increase the risk of offspring neurodevelopmental disorder - particularly later receipt of autism spectrum disorder - according to a recent review of the published research. https://t.co/QoKhkGeATn

Oct 14, 2021 · 5 likes · 2 shares · 189 followers View post →
Healthcare-Global
@healthcare-global.bsky.social · Bluesky

pmc.ncbi.nlm.nih.gov/articles/PMC... Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis - PMC

Sep 23, 2025 · 5 likes View post →
Saber Atualizado
@AtualizadoSaber · X

Hipertermia - um aumento descontrolado da temperatura corporal - durante a gravidez atua como um teratógeno em alguns animais e pode causar morte fetal. (1) Referências:

Sep 26, 2025 · 4 likes · 1 share · 30,150 followers View post →
Molecular Autism
@MolecularAutism · X

Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis @HopRobertDebr @Dr34dy @APHP @Inserm https://t.co/hY7UPFQqvn https://t.co/vfqF6oIt8s

Sep 20, 2021 · 3 likes · 2 shares · 1,697 followers View post →

All mentions

cg
@NorteSur7 · X

RT @kiityc: @AshleyGWinter Do they know untreated maternal fever is bad for foetal brain tissue? People take Tylenol to treat pain and fe…

Oct 11, 2025 · 3 shares · 4,680 followers View post →
gatoveio.bsky.social
@gatoveio.bsky.social · Bluesky

youtu.be/8M_WWkT99P8?...

Oct 3, 2025 · 1 like · 1 share View post →
Thiago Roitman
@thiagomelo.bsky.social · Bluesky

Queria muito ser presidente pra poder virar pra Laura e dizer: DEIXA EU COLOCAR ESSE VÍDEO EM REDE NACIONAL NO INTERVALO DA NOVELA OU NA FINAL DO CAMPEONATO BRASILEIRO??? youtu.be/8M_WWkT99P8?...

Sep 30, 2025 · 10 likes · 2 shares View post →
Thiago Roitman
@thiagomelo.bsky.social · Bluesky

Queria muito ser presidente pra poder virar pra Laura e dizer: DEIXA EU COLOCAR ESSE VÍDEO EM REDE NACIONAL NO INTERVALO DA NOVELA OU NA FINAL DO CAMPEONATO BRASILEIRO??? youtu.be/8M_WWkT99P8?...

Sep 30, 2025 · 2 likes View post →
Silvana Marques
@silmarq.bsky.social · Bluesky

Pensa num vídeo necessário! @lauramarise.bsky.social explicando por A+B por que não dá pra gestante cair na desinformação do presidente laranja dos EUA youtu.be/8M_WWkT99P8?...

Sep 30, 2025 View post →
Michael Serra
@michaelserra.com · Bluesky

Didática e roteiros excepcionais. Vale espalhar. youtu.be/8M_WWkT99P8?...

Sep 30, 2025 View post →
Klinger Neves
@Kli_Nev · X

RT @AtualizadoSaber: Hipertermia - um aumento descontrolado da temperatura corporal - durante a gravidez atua como um teratógeno em alguns…

Sep 26, 2025 · 1 share · 3,851 followers View post →
superjaded
@Superjaded13 · X

Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis | Molecular Autism | Full Text https://t.co/kZQHcSI7hu

Sep 26, 2025 · 303 followers View post →
Saber Atualizado
@AtualizadoSaber · X

Hipertermia - um aumento descontrolado da temperatura corporal - durante a gravidez atua como um teratógeno em alguns animais e pode causar morte fetal. (1) Referências:

Sep 26, 2025 · 4 likes · 1 share · 30,150 followers View post →
Dra. Tauany
@TauanyMRL · X

Febre por só também é fator de risco para distúrbios no neurodesenvolvimento… Gente, calma! https://t.co/HwPp0VjIzL https://t.co/p6blHAF5Fj

Sep 26, 2025 · 243 followers View post →
raquel cozer
@raqcozer · X

@LandisLynn1 @BarackObama Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis https://t.co/SjyCPffnOb

Sep 25, 2025 · 10,860 followers View post →
dearappauthors
@dearappauthors · X

RT @kiityc: @AshleyGWinter Do they know untreated maternal fever is bad for foetal brain tissue? People take Tylenol to treat pain and fe…

Sep 24, 2025 · 3 shares · 371 followers View post →
Ajin Cherian
@itsajin · X

@admsmith249687 @CFSH67 @DrNeilStone A meta-analysis https://t.co/U7WYbgdoYa

Sep 24, 2025 · 273 followers View post →
Lusitan1981
@lusitan1981 · X

@DAljubarrota @inesdealmeida90 A própria febre alta durante a gravidez aumenta o risco de problemas de desenvolvimento neurológicos segundo alguns estudos. https://t.co/9ZZ2qxWgBm

Sep 24, 2025 · 1,048 followers View post →
Alan Fung
@aroundtheworls · X

@jamesisjjj @SpencerHakimian The problem is the fever not the drug used to reduce the fever. ASD rates are even higher among those who don't take drugs to reduce fevers- https://t.co/zlIsLyaH8b

Sep 24, 2025 · 1 like · 36 followers View post →
6ix Dweller
@buddah67 · X

@SenWarren Highly irresponsible to jump to that conclusion, based on one study when HAVING A FEVER while you are pregnant may cause NDD.  "Additional evidence supported the association between fever during pregnancy & increased risk for NDD... 1 of many studies https://t.co/bjVMgecQyU

Sep 23, 2025 · 707 followers View post →
What in the actual...
@AsxItxLies · X

@francoboca @TheMaineWonk @thetimes Having a high fever can cause NDDs at or above the same ratio as reported in this study. https://t.co/GwqT5CINYk

Sep 23, 2025 · 2 likes · 217 followers View post →
Healthcare-Global
@healthcare-global.bsky.social · Bluesky

pmc.ncbi.nlm.nih.gov/articles/PMC... Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis - PMC

Sep 23, 2025 · 5 likes View post →
Soph
@Sophs0123 · X

‘Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis’ Have a read of what having a fever during pregnancy does to the baby!! You dimwits Trump & RFK Jr… #TYLENOL #paracetamol https://t.co/CirYl8J4Vk

Sep 22, 2025 · 1 like · 913 followers View post →
Tam.
@c3convertase · X

RT @kiityc: @AshleyGWinter Do they know untreated maternal fever is bad for foetal brain tissue? People take Tylenol to treat pain and fe…

Sep 7, 2025 · 3 shares · 4,197 followers View post →
Dr Katie Cairns
@kiityc · X

@AshleyGWinter Do they know untreated maternal fever is bad for foetal brain tissue? People take Tylenol to treat pain and fever. It may be the fever, not the drug. Influenza and Covid cause fever…and he wants to ban those vaccines. https://t.co/SaBI2z18mh https://t.co/gFCFegmaLA

Sep 6, 2025 · 13 likes · 3 shares · 3,105 followers View post →
Boian
@boianspeaks · X

@VikiLovesFACS @P_McCulloughMD Fever is one of the most common side effects of covid vaccination. You are encouraging pregnant mothers to risk a guaranteed fever risk, over a theoretical risk of a covid-infection related fever. ⚠️ https://t.co/jovuhAfBzr ⚠️ https://t.co/dqpK0DCVjd https://t.co/KCHWQQ0Ouq https://t.co/fHhSfq4rvA

Oct 29, 2023 · 831 followers View post →
Boian
@boianspeaks · X

@VikiLovesFACS @ImperialMed @theipaper @P_McCulloughMD Fever is one of the most common side effects of covid vaccination. You are encouraging pregnant mothers to risk a guaranteed fever risk, over a theoretical risk of a covid-infection related fever. ⚠️ https://t.co/jovuhAfBzr ⚠️ https://t.co/dqpK0DCVjd https://t.co/KCHWQQ0Ouq https://t.co/6h8igTFK3A

Oct 29, 2023 · 831 followers View post →
Boian
@boianspeaks · X

@VikiLovesFACS @P_McCulloughMD Fever is one of the most common side effects of covid vaccination. You are encouraging pregnant mothers to risk a guaranteed fever risk, over a theoretical risk of a covid-infection related fever. ⚠️ https://t.co/jovuhAfBzr ⚠️ https://t.co/dqpK0DCVjd https://t.co/KCHWQQ0Ouq https://t.co/2jQ1KsUPsc

Oct 29, 2023 · 2 likes · 831 followers View post →
Dave Austin
@DaveAus23503512 · X

@Ari58394958 @liellu142RI @MarkWKlineMD1 Any research to back up the SLP’s claim that masking caused a 300% plus increase in speech development delays? Febrile maternal illness associated with developmental delay https://t.co/8Q4r7ke8dc

Jun 4, 2023 · 211 followers View post →
Patricia Hyland Bowman
@bowman_hyland · X

RT @Hragy: @JoJoYangMD What’s the advice to a pregnant woman who developed severe prolonged high fever due to COVID19 infection during the…

Jul 6, 2022 · 1 share · 153 followers View post →
Hany Ragy
@Hragy · X

@JoJoYangMD What’s the advice to a pregnant woman who developed severe prolonged high fever due to COVID19 infection during the brain development? https://t.co/kXrWOGMOYm

Jul 6, 2022 · 1 like · 1 share · 80,542 followers View post →
tom C
@85tmoney85 · X

@MaeYeg @YourAlberta https://t.co/fqgx13u4QQ

Oct 26, 2021 · 1 like · 3 followers View post →
Make A Stand 4 Autism
@MakeAStandOrg · X

RT @NofOneAutism: FEVER DURING PREGNANCY seems to increase the risk of offspring neurodevelopmental disorder - particularly later receipt o…

Oct 14, 2021 · 2 shares · 1,136 followers View post →
N of One
@NofOneAutism · X

FEVER DURING PREGNANCY seems to increase the risk of offspring neurodevelopmental disorder - particularly later receipt of autism spectrum disorder - according to a recent review of the published research. https://t.co/QoKhkGeATn

Oct 14, 2021 · 5 likes · 2 shares · 189 followers View post →
H Kiely
@liberkiely · X

RT @EvidentlyBetter: Our latest Learning Disabilities & Autism bulletin: Fever during pregnancy as a risk factor for neurodevelopmental dis…

Oct 5, 2021 · 1 share · 396 followers View post →
Evidently Better
@EvidentlyBetter · X

Our latest Learning Disabilities & Autism bulletin: Fever during pregnancy as a risk factor for neurodevelopmental disorders - results from a systematic review and meta-analysis; Autistic individuals are more likely to be LGBTQ+; & more https://t.co/Wc3StF85nU

Oct 1, 2021 · 1 like · 1 share · 623 followers View post →
Paul Whiteley
@PaulWhiteleyPhD · X

Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis https://t.co/auEsa9kTqX "Maternal exposure to fever during pregnancy increased the risk of NDD in offspring with an OR of 1.24."

Sep 21, 2021 · 4,959 followers View post →
#Autism
@Autism_Journal · X

Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis https://t.co/JAZs9tyGGp #PubMed #Autism

Sep 20, 2021 · 388 followers View post →
GW4 Neurodevelopmental Neurodiversity Network
@neurodnetwork · X

RT @MolecularAutism: Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-an…

Sep 20, 2021 · 2 shares · 1,445 followers View post →
Molecular Autism
@MolecularAutism · X

Fever during pregnancy as a risk factor for neurodevelopmental disorders: results from a systematic review and meta-analysis @HopRobertDebr @Dr34dy @APHP @Inserm https://t.co/hY7UPFQqvn https://t.co/vfqF6oIt8s

Sep 20, 2021 · 3 likes · 2 shares · 1,697 followers View post →