JGH Open September 2021 PMID 34584964

Gut microbiota dysbiosis in functional gastrointestinal disorders: Underpinning the symptoms and pathophysiology.

Lai Wei, Rajan Singh, Seungil Ro, Uday C Ghoshal

Download social card

Mentions

53
Peak: 14 in Feb 2022
across 5 sources since Mar 2021

Extended reach

81,546
potential audience

Total likes

181

Video views

2,345

Mentions per month

Mar 2021 – Jan 2025

Where it's discussed

  • X / Twitter36 posts
  • News9 articles
  • YouTube4 videos
  • Reddit2 posts
  • Blogs2 articles

AI synopsis

What people are saying

Several discussions emphasize the role of gut microbiota dysbiosis in GI symptoms, using words like 'critical role' and 'underpinning' which suggest that participants see this as an important finding. The tone indicates curiosity and a recognition of the research's relevance for future treatments, though some posts remain more introductory, reflecting moderate perceived impact and engagement.

AgreementModerate agreement

Most discussions show support for the importance of the research, with participants highlighting the connection between gut microbiota and GI disorders, indicating moderate consensus.

InterestHigh interest

Posts express high curiosity, with multiple mentions of the microbiota's role and potential clinical implications, reflecting strong engagement.

EngagementModerate engagement

Many posts reference external research, methods, and implications, demonstrating a meaningful level of deep engagement, though not overwhelmingly detailed.

ImpactModerate impact

There is a sense that the publication is viewed as significant within gastroenterological research, but the overall perception of immediate impact remains moderate.

Abstract in brief

  • Gut microbiota dysbiosis plays a significant role in functional gastrointestinal disorders (FGIDs), with alterations in microbial species linked to symptoms such as gut dysmotility, hypersensitivity, immune changes, and barrier dysfunction.
  • Despite advances in understanding these relationships, the exact cellular and molecular mechanisms connecting gut microbiota to FGIDs remain unclear due to challenges like the lack of suitable animal models, limited longitudinal studies, and insufficient data on disease-specific changes.
  • Current treatments targeting dysbiosis include dietary modifications, antibiotics, probiotics, and fecal microbiota transplants, with ongoing research aimed at uncovering new therapeutic options based on gut microbiota's role in maintaining gut health.

Top posts

Most liked on X and Bluesky
GutMicrobiota Health
@GMFHx · X

What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh & colleagues explore how gut microbiota-derived molecules impact gut motility & potential implications for the clinical setting https://t.co/s65pKitWTJ https://t.co/StwsQSomAo

Feb 3, 2022 · 77 likes · 20 shares · 35,521 followers View post →
Rajan Singh
@Rajan___Singh · X

Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro @NatRevGastroHep @JNMjournal @NGMJournal @esnm_eu

Mar 28, 2021 · 35 likes · 12 shares · 1,473 followers View post →
Kewin Siah
@KewinSiah · X

Who's who in DGBI:

Apr 10, 2021 · 14 likes · 2 shares · 2,347 followers View post →
Rajan Singh
@Rajan___Singh · X

@KewinSiah @MarkPimentelMD @npichetshotemd @CedarsSinai @UCLAGIHep @INMAssociation @jonathanlwj @sunnyheiwong @anma_i @IBS_Maastricht @drkeithsiau In our recent review(https://t.co/OZaqlgllDK @LaiWei @Rajan___Singh #UdayGhoshal), we proposed that H2S producing #GutMicrobes might play a critical role in IBS-D. The reason we love #GutScience, now here is the evidence! @AmJGastro @MarkPimentelMD group! Congratulations!

Sep 19, 2022 · 14 likes · 2 shares · 1,473 followers View post →
Emel Cihan
@Emell_Cihan · X

Gut microbiota dysbiosis in functional gastrointestinal disorders: Underpinning the symptoms and pathophysiology https://t.co/1y6i23jOXz

Feb 3, 2022 · 1 like · 880 followers View post →
Walter Huamán
@WalterH64937350 · X

Gut microbiota dysbiosis in functional gastrointestinal disorders: Underpinning the symptoms and pathophysiology https://t.co/SaeHlE7jgL

Mar 28, 2021 · 1 like · 249 followers View post →

All mentions

Ace Bryan Sotelo Cabal
@ace_cabal · X

RT @Rajan___Singh: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro…

Jan 29, 2025 · 12 shares · 1,134 followers View post →
IndianNeurogastroenterology & Motility Association
@INMAssociation · X

RT @Rajan___Singh: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro…

Jan 12, 2025 · 12 shares · 373 followers View post →
kara gross margolis
@karagm2009 · X

RT @Rajan___Singh: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro…

Jan 12, 2025 · 12 shares · 688 followers View post →
Gut-Brain Science
@GutBrainScience · X

RT @Rajan___Singh: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro…

Jan 12, 2025 · 12 shares · 616 followers View post →
Ayesha Shah
@AyeshaShah717 · X

RT @Rajan___Singh: @KewinSiah @MarkPimentelMD @npichetshotemd @CedarsSinai @UCLAGIHep @INMAssociation @jonathanlwj @sunnyheiwong @anma_i @I…

May 12, 2023 · 2 shares · 33 followers View post →
IndianNeurogastroenterology & Motility Association
@INMAssociation · X

RT @Rajan___Singh: @KewinSiah @MarkPimentelMD @npichetshotemd @CedarsSinai @UCLAGIHep @INMAssociation @jonathanlwj @sunnyheiwong @anma_i @I…

Sep 19, 2022 · 2 shares · 373 followers View post →
Rajan Singh
@Rajan___Singh · X

@KewinSiah @MarkPimentelMD @npichetshotemd @CedarsSinai @UCLAGIHep @INMAssociation @jonathanlwj @sunnyheiwong @anma_i @IBS_Maastricht @drkeithsiau In our recent review(https://t.co/OZaqlgllDK @LaiWei @Rajan___Singh #UdayGhoshal), we proposed that H2S producing #GutMicrobes might play a critical role in IBS-D. The reason we love #GutScience, now here is the evidence! @AmJGastro @MarkPimentelMD group! Congratulations!

Sep 19, 2022 · 14 likes · 2 shares · 1,473 followers View post →
Marissa Sgro
@MarissaSgro · X

RT @Rajan___Singh: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro…

Feb 3, 2022 · 12 shares · 285 followers View post →
Cocina adaptada autismo
@cocinadaptada · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 355 followers View post →
Dr Fermin Vinaixa
@DrFerminVinaixa · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 330 followers View post →
Felipe Morillo
@morillo_fe · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 749 followers View post →
Rajan Singh
@Rajan___Singh · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 1,473 followers View post →
Oscar Andres
@OscarAndresMD · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 552 followers View post →
Viviana
@VivianAya93 · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 133 followers View post →
katie wright
@katiewr31413491 · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 12,932 followers View post →
Peace Park
@peaceppark · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 17 followers View post →
Emel Cihan
@Emell_Cihan · X

Gut microbiota dysbiosis in functional gastrointestinal disorders: Underpinning the symptoms and pathophysiology https://t.co/1y6i23jOXz

Feb 3, 2022 · 1 like · 880 followers View post →
Noemí Martínez
@Mimimar46 · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 268 followers View post →
козел кефир
@cacaoXtawco · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 392 followers View post →
Eros
@ErosSowinski · X

RT @GMFHx: What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh…

Feb 3, 2022 · 20 shares · 531 followers View post →
GutMicrobiota Health
@GMFHx · X

What we know so far on the role of gut microbiota changes in functional gastrointestinal disorders? @LaiWeiLisa, @Rajan___Singh & colleagues explore how gut microbiota-derived molecules impact gut motility & potential implications for the clinical setting https://t.co/s65pKitWTJ https://t.co/StwsQSomAo

Feb 3, 2022 · 77 likes · 20 shares · 35,521 followers View post →
Ranjan Sinha
@Ranjan_Health · X

Trying to cure #irritablebowelsyndrome without assessing the #gutmicrobiome, host #genetics and its interaction with #food is like trying to cure #diabetestype2 without measuring #bloodsugar. Glad to see Increasing research publ…https://t.co/y8dWVRBkgo https://t.co/9WqXjGBvOC

Nov 7, 2021 · 1 like · 38 followers View post →
metagen human papers
@metagen_human · X

Gut microbiota dysbiosis in functional gastrointestinal disorders: Underpinning the symptoms and pathophysiology https://t.co/vwGj4RTiLj

Oct 3, 2021 · 1 like · 75 followers View post →
FMT Articles & Papers
@fmtarticles · X

Gut microbiota dysbiosis in functional gastrointestinal disorders: Underpinning the symptoms and pathophysiology https://t.co/KXzBovTUD3 https://t.co/buf2jlKTgG

Sep 29, 2021 · 475 followers View post →
Symbiosis papers
@Symbiosispapers · X

Gut microbiota dysbiosis in functional gastrointestinal disorders: Underpinning the symptoms and pathophysiology https://t.co/YRyjUyMtMa

Sep 29, 2021 · 1,113 followers View post →
Journal of Gastroenterology and Hepatology
@JGHofficial · X

RT @KewinSiah: Who's who in DGBI:

Apr 15, 2021 · 2 shares · 5,570 followers View post →
@citologia_biopsia
@CBiopsia · X

RT @KewinSiah: Who's who in DGBI:

Apr 11, 2021 · 2 shares · 128 followers View post →
Kewin Siah
@KewinSiah · X

Who's who in DGBI:

Apr 10, 2021 · 14 likes · 2 shares · 2,347 followers View post →
Mu-Ming Chien
@MuMingChien · X

RT @RAJAN_SGPGI: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro @N…

Mar 29, 2021 · 12 shares · 120 followers View post →
.c.a.r.l.o.s
@galantee28 · X

RT @RAJAN_SGPGI: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro @N…

Mar 29, 2021 · 12 shares · 35 followers View post →
Julia Dallman
@DallmanLab · X

RT @RAJAN_SGPGI: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro @N…

Mar 29, 2021 · 12 shares · 298 followers View post →
Rome PsychoGastroenterology
@RomeGastroPsych · X

RT @RAJAN_SGPGI: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro @N…

Mar 29, 2021 · 12 shares · 3,728 followers View post →
Walter Huamán
@WalterH64937350 · X

Gut microbiota dysbiosis in functional gastrointestinal disorders: Underpinning the symptoms and pathophysiology https://t.co/SaeHlE7jgL

Mar 28, 2021 · 1 like · 249 followers View post →
ANMS
@ANMSociety · X

RT @RAJAN_SGPGI: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro @N…

Mar 28, 2021 · 12 shares · 3,106 followers View post →
Cecelia I. Nelson, PhD
@ThatDocStudent · X

RT @RAJAN_SGPGI: Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro @N…

Mar 28, 2021 · 12 shares · 548 followers View post →
Rajan Singh
@Rajan___Singh · X

Please check out our recently published review article! https://t.co/OZaqlgCoFK @AmerGastroAssn @ANMSociety @AGA_Gastro @NatRevGastroHep @JNMjournal @NGMJournal @esnm_eu

Mar 28, 2021 · 35 likes · 12 shares · 1,473 followers View post →