We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR that recognizes HLA-A2 (class I)! They prevent #GraftvsHostDisease & traffic to #transplanted A2+ #pancreatic #islets! #thefutureishere https://t.co/dEePITSfD2 https://t.co/0J22xXhgg5
Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance.
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Aug 2021 – Jan 2024Where it's discussed
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X / Twitter60 posts
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News9 articles
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YouTube2 videos
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What people are saying
Discussions demonstrate strong support and curiosity, with phrases like 'hope to see this work in human trials' and 'created regulatory T cells using gene editing,' emphasizing excitement and recognition of the research’s significance. The tone is positive and forward-looking, showcasing the perceived high impact of engineering T cells for transplant tolerance.
Most discussions express support or curiosity about the research, highlighting its promising potential.
Posts show high interest, with users engaging in questions and appreciation for the advancements.
Several comments include detailed descriptions, acknowledgments, and references, indicating active participation.
The frequent mention of clinical implications, gene editing techniques, and potential for transplantation highlight the significant impact of this research.
Top posts
Most liked on X and BlueskyPrecision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance https://t.co/waWTEqYZCG #biorxiv_immuno
Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance https://t.co/497mEYxKYs #bioRxiv
Our #TCR deficient HLA-A2 #specific #CAR #Tregs that prevent #graftvshost #disease in #humanized #mice were featured as part of @BioCentury’s roundup of #translational #news! #immunologymatters https://t.co/AFfPZOflDB https://t.co/8y4G2Mpczy https://t.co/TyKFUADiCe
New Research: Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance: Infusion of regulatory T cells (Tregs) engineered with a chimeric antigen receptor (CAR) targeting… https://t.co/GrbpVJM8Dj #immunology
What are the implications for #aging & #longevity of our work engineering #Tregs for #transplantation #tolerance? Thank you to Danielle Davis for creating this video, with the initiative and support of @DayOneVC! #immunologymatters https://t.co/KmYLVlM5QY https://t.co/8y4G2Mpczy https://t.co/C1s1lS9fVY
All mentions
Transforming Immune Cells into Living Drugs with Dr. Ferreira
Dr. Leonardo Ferreira, Assistant Professor at the Medical University of South Carolina, focuses on immune tolerance and engineering T regulatory cells (Tregs) to create cell therapies for autoimmune diseases, cancer…
Engineering Tregs for Transplant Tolerance and Longevity
In this video, Leonardo Ferreira, PhD from UCSF, discusses his work on engineering regulatory T cells (Tregs) for transplantation tolerance. He explores the implications of this research for aging and longevity…
RT @Madam_Mito: https://t.co/09oOR9o4Yg Interesting talk. @enhancerleo #Aging
RT @Madam_Mito: https://t.co/09oOR9o4Yg Interesting talk. @enhancerleo #Aging
https://t.co/09oOR9o4Yg Interesting talk. @enhancerleo #Aging
RT @enhancerleo: Unfreeze your science! Thank you @CRYOPDP and Guilherme Cardoso for the opportunity of being interviewed for the inaugural…
Unfreeze your science! Thank you @CRYOPDP and Guilherme Cardoso for the opportunity of being interviewed for the inaugural episode of your new podcast. #immunologymatters #changingwhatspossible https://t.co/3X1tLSc9qp https://t.co/CeIX0uo4hE
In 2021, I co-authored a study genetically engineering immunosuppressive human regulatory T cells (CAR Tregs) that traffic to transplanted human pancreatic islets. https://t.co/6e2U348J6S
RT @enhancerleo: Our #TCR deficient HLA-A2 #specific #CAR #Tregs that prevent #graftvshost #disease in #humanized #mice were featured as p…
RT @HIRN_CC: Highlighting #HIRN supported manuscript: Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cel…
RT @HIRN_CC: Highlighting #HIRN supported manuscript: Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cel…
RT @HIRN_CC: Highlighting #HIRN supported manuscript: Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cel…
Highlighting #HIRN supported manuscript: Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance in @FrontImmunol https://t.co/gpWFNwmTtW @enhancerleo @leoferreiralab @kickassscience1 @QizhiTang #HIRNfundedResearch
Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance https://t.co/zGfOWqyIlo
RT @enhancerleo: Células regulatórias T reeducadas utilizando edição genética hoje no Público! Pela inigualável @AndreaCF @Publico. #immuno…
Células regulatórias T reeducadas utilizando edição genética hoje no Público! Pela inigualável @AndreaCF @Publico. #immunologymatters #CARTregs https://t.co/W3XAGEosab https://t.co/8y4G2Mpczy https://t.co/MrzQxXBohN
RT @enhancerleo: What are the implications for #aging & #longevity of our work engineering #Tregs for #transplantation #tolerance? Thank yo…
RT @enhancerleo: Our #TCR deficient HLA-A2 #specific #CAR #Tregs that prevent #graftvshost #disease in #humanized #mice were featured as p…
RT @enhancerleo: What are the implications for #aging & #longevity of our work engineering #Tregs for #transplantation #tolerance? Thank yo…
What are the implications for #aging & #longevity of our work engineering #Tregs for #transplantation #tolerance? Thank you to Danielle Davis for creating this video, with the initiative and support of @DayOneVC! #immunologymatters https://t.co/KmYLVlM5QY https://t.co/8y4G2Mpczy https://t.co/C1s1lS9fVY
Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance.#Tregcelltherapies @DrGauravNarula @CTCTC_tmc https://t.co/95Bzgo3gwB
Precision Engineering of an Anti-HLA-A2 CAR in Regulatory T Cells for Transplant Immune Tolerance https://t.co/1eMJoLgY6u #CART #bmtsm #CARTcell #immunotherapy #tcellrx #ICAN #CRS #CARTcells #CellTherapy @ASTCT @FrontImmunol Hope to see this work nicely in human trials!!
Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance https://t.co/vLwrAGDq0U
RT @enhancerleo: Our #TCR deficient HLA-A2 #specific #CAR #Tregs that prevent #graftvshost #disease in #humanized #mice were featured as p…
RT @enhancerleo: Our #TCR deficient HLA-A2 #specific #CAR #Tregs that prevent #graftvshost #disease in #humanized #mice were featured as p…
RT @enhancerleo: Our #TCR deficient HLA-A2 #specific #CAR #Tregs that prevent #graftvshost #disease in #humanized #mice were featured as p…
RT @enhancerleo: Our #TCR deficient HLA-A2 #specific #CAR #Tregs that prevent #graftvshost #disease in #humanized #mice were featured as p…
Our #TCR deficient HLA-A2 #specific #CAR #Tregs that prevent #graftvshost #disease in #humanized #mice were featured as part of @BioCentury’s roundup of #translational #news! #immunologymatters https://t.co/AFfPZOflDB https://t.co/8y4G2Mpczy https://t.co/TyKFUADiCe
Scientists demonstrate that genome-engineered mono-antigen-specific A2-CAR #Tregs localize to HLA-A2-expressing grafts. Read the full article here: https://t.co/Q2Nher2gPt https://t.co/VMytJfAhNZ
RT @FrontImmunol: New Research: Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immu…
RT @FrontImmunol: New Research: Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immu…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @FrontImmunol: New Research: Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immu…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
From our newest core faculty member Qizhi Tang @QizhiTang https://t.co/NRW1cW3FbF
RT @FrontImmunol: New Research: Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immu…
New Research: Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance: Infusion of regulatory T cells (Tregs) engineered with a chimeric antigen receptor (CAR) targeting… https://t.co/GrbpVJM8Dj #immunology
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
RT @enhancerleo: We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR t…
We created #human #regulatory #Tcells (#Tregs) where their (class II-restricted) #TCR was replaced via #CRISPR w/ a #CAR that recognizes HLA-A2 (class I)! They prevent #GraftvsHostDisease & traffic to #transplanted A2+ #pancreatic #islets! #thefutureishere https://t.co/dEePITSfD2 https://t.co/0J22xXhgg5
RT @3DiMMUNE: can CAR-Treg function normally? This preprint showed they could survive for 2 weeks. Precision engineering of an anti-HL…
RT @biorxivpreprint: Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune toleranc…
can CAR-Treg function normally? This preprint showed they could survive for 2 weeks. Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance https://t.co/jOroaIChrS
Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance https://t.co/B3vhBH6vsU
RT @biorxivpreprint: Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune toleranc…
RT @biorxiv_immuno: Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance…
RT @biorxiv_immuno: Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance…
RT @biorxivpreprint: Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune toleranc…
Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance https://t.co/BYkki6er6D
Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance https://t.co/waWTEqYZCG #biorxiv_immuno
Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance https://t.co/497mEYxKYs #bioRxiv