Front Pharmacol September 2021 PMID 34658858

Intermittent Fasting Inhibits High-Fat Diet-Induced Atherosclerosis by Ameliorating Hypercholesterolemia and Reducing Monocyte Chemoattraction.

Yuanli Chen, Jiamin Su, Yali Yan, Qian Zhao, Jialing Ma, Mengmeng Zhu, Xiaoyu He, Baotong Zhang, Hongmei Xu, Xiaoxiao Yang, Yajun Duan, Jihong Han

Mentions

9
Peak: 2 in Oct 2021
across 2 sources since Sep 2021

Extended reach

21,188
potential audience

Total likes

33

Video views

909

Mentions per month

Sep 2021 – Jul 2025

Where it's discussed

  • X / Twitter7 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions exemplify a high level of agreement and interest, with posts highlighting how intermittent fasting reduces plaque formation and promotes plaque stability, such as mention of 'inhibiting monocyte adhesion' and 'reducing circulating CCL2 levels.' The tone is enthusiastic and acknowledges the potential health benefits, reflecting its perceived high impact on cardiovascular research and health practices.

AgreementStrong agreement

Most posts strongly endorse the findings, emphasizing the protective role of intermittent fasting against atherosclerosis.

InterestHigh interest

The discussions reflect high engagement, with users showing curiosity and enthusiasm about the potential health benefits highlighted.

EngagementModerate engagement

Posts reference specific mechanisms, such as reduced monocyte adhesion and lowering cholesterol, indicating a deeper understanding and interest in the research details.

ImpactHigh impact

The discussions suggest that many perceive this research could significantly influence health strategies and promote further investigation into fasting protocols.

Abstract in brief

  • Intermittent fasting (IF) helps prevent atherosclerosis caused by high-fat diets by lowering cholesterol levels, reducing plaque buildup, and increasing plaque stability in mice.
  • The study showed that IF decreases monocyte attraction and adhesion to blood vessel walls, partly by reducing chemokines and adhesion molecules, which in turn limits inflammation and plaque formation.
  • Overall, the findings suggest that IF could be a promising strategy for preventing or treating atherosclerosis through its effects on cholesterol, immune cell recruitment, and inflammation.]

Top posts

Most liked on X and Bluesky
htw
@heniek_htw · X

▶️ Intermittent Fasting treatment alleviates development of atherosclerosis & increases plaque stability. Mechanistically, IF inhibits monocyte adhesion & infiltration to endothelium by reducing & circulating CCL2 levels & Ly6Chigh monocytes.

Oct 5, 2021 · 5 likes · 1 share · 11,358 followers View post →
İntizam Seyda Durgun
@IntizamD · X

(1)“Intermittent Fasting Inhibits High-Fat Diet-Induced Atherosclerosis by Ameliorating Hypercholesterolemia and Reducing Monocyte Chemoattraction.”, Front Pharmacol. 2021 Sep 30;12:719750. doi: 10.3389/fphar.2021.719750. eCollection 2021. https://t.co/EmfVtzp9s6

Dec 31, 2022 · 1 like · 603 followers View post →
شـاهـين♂️
@bioApproach_ · X

@abwmn13 @bakhsh_reda نعم، يساهم في العلاج وفي تقليل التصلب الذي حصل وال necrotic cores في التصلب نفسه من خلال تقليل الخلايا الالتهابية في المكان. راجع: doi: 10.3389/fphar.2021.719750.

Jul 21, 2025 · 1 like · 233 followers View post →
Frontiers - Pharmacology and Toxicology
@FrontPharmacol · X

New Research: Intermittent Fasting Inhibits High-Fat Diet–Induced Atherosclerosis by Ameliorating Hypercholesterolemia and Reducing Monocyte Chemoattraction https://t.co/CRukzZ3KjL #pharmacology

Sep 30, 2021 · 6,142 followers View post →
Eve Beavers is espacetimeCO & espacetimeNOT
@espacetimeCO · X

RT @heniek_htw: ▶️ Intermittent Fasting treatment alleviates development of atherosclerosis & increases plaque stability. Mechanistically,…

Oct 5, 2021 · 1 share · 911 followers View post →
Optimistic Cavs Fan (Hope)
@BBerbari_3K · X

@FortMinorLinkin @aantcsz @OvOBrezzzy Here ya go https://t.co/T6EVNP1Zr1

Sep 27, 2022 · 725 followers View post →

All mentions

شـاهـين♂️
@bioApproach_ · X

@abwmn13 @bakhsh_reda نعم، يساهم في العلاج وفي تقليل التصلب الذي حصل وال necrotic cores في التصلب نفسه من خلال تقليل الخلايا الالتهابية في المكان. راجع: doi: 10.3389/fphar.2021.719750.

Jul 21, 2025 · 1 like · 233 followers View post →
Idiopathic Confusion
@WFPB_Longevity · X

Intermittent Fasting Inhibits High-Fat Diet–Induced Atherosclerosis by Ameliorating Hypercholesterolemia and Reducing Monocyte Chemoattraction https://t.co/9s1y1LBVWv

Feb 7, 2023 · 303 followers View post →
İntizam Seyda Durgun
@IntizamD · X

(1)“Intermittent Fasting Inhibits High-Fat Diet-Induced Atherosclerosis by Ameliorating Hypercholesterolemia and Reducing Monocyte Chemoattraction.”, Front Pharmacol. 2021 Sep 30;12:719750. doi: 10.3389/fphar.2021.719750. eCollection 2021. https://t.co/EmfVtzp9s6

Dec 31, 2022 · 1 like · 603 followers View post →
Optimistic Cavs Fan (Hope)
@BBerbari_3K · X

@FortMinorLinkin @aantcsz @OvOBrezzzy Here ya go https://t.co/T6EVNP1Zr1

Sep 27, 2022 · 725 followers View post →
Eve Beavers is espacetimeCO & espacetimeNOT
@espacetimeCO · X

RT @heniek_htw: ▶️ Intermittent Fasting treatment alleviates development of atherosclerosis & increases plaque stability. Mechanistically,…

Oct 5, 2021 · 1 share · 911 followers View post →
htw
@heniek_htw · X

▶️ Intermittent Fasting treatment alleviates development of atherosclerosis & increases plaque stability. Mechanistically, IF inhibits monocyte adhesion & infiltration to endothelium by reducing & circulating CCL2 levels & Ly6Chigh monocytes.

Oct 5, 2021 · 5 likes · 1 share · 11,358 followers View post →
Frontiers - Pharmacology and Toxicology
@FrontPharmacol · X

New Research: Intermittent Fasting Inhibits High-Fat Diet–Induced Atherosclerosis by Ameliorating Hypercholesterolemia and Reducing Monocyte Chemoattraction https://t.co/CRukzZ3KjL #pharmacology

Sep 30, 2021 · 6,142 followers View post →