March 2022 PMID 34687438

Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysis.

Luana Farias de Oliveira, Eimear Dolan, Paul A Swinton, Krzysztof Durkalec-Michalski, Guilherme G Artioli, Lars R McNaughton, Bryan Saunders

Mentions

56
Peak: 26 in Oct 2021
across 4 sources since Oct 2021

Extended reach

415,023
potential audience

Total likes

13,077

Video views

251,724

Mentions per month

Oct 2021 – Aug 2025

Where it's discussed

  • X / Twitter48 posts
  • YouTube3 videos
  • News3 articles
  • Facebook2 posts

AI synopsis

What people are saying

Several discussions highlight the effectiveness of extracellular buffering supplements, particularly sodium bicarbonate, stating that they lead to substantial increases in blood bicarbonate concentration benefiting exercise performance. Phrases such as 'Great read' and 'suitable supplements' reflect enthusiasm and endorsement, while questions about individualization of sodium bicarbonate ingestion suggest an active interest in practical applications, enriching the overall context of the discourse.

AgreementModerate agreement

Many posts reflect positive views on the publication and its findings about buffering supplements, though not all users express outright endorsement.

InterestHigh interest

The discussions indicate a high level of curiosity regarding the implications of the supplements for exercise performance.

EngagementModerate engagement

A blend of users shares insights and queries about methods, showing a moderate depth of engagement rather than mere surface-level comments.

ImpactHigh impact

Users appear to believe that the findings could significantly influence exercise practices and training protocols.

Abstract in brief

  • Extracellular buffering agents like sodium bicarbonate, sodium citrate, and sodium/calcium lactate are studied for their potential to enhance exercise performance, though factors influencing their effectiveness are still debated.
  • A systematic review analyzing 189 studies showed that these supplements significantly raised blood bicarbonate levels and improved exercise capacity, particularly for activities lasting between 0.5 to 10 minutes and over 10 minutes.
  • The study also noted that the extent of blood bicarbonate increase impacts performance; larger increases (above 4 mmol L) correlated with better exercise outcomes compared to smaller increases.

Top posts

Most liked on X and Bluesky
Bryan Saunders
@Bicycle_Bryan · X

An idea that started out four years ago, nice to see it come to fruition. Will post a thread on the main outcomes next week @luanaindaia @eimeardol @PaulSwinton9 @Artioli_Gui @LarsMcnaughton https://t.co/kC0ZnQB6QI

Oct 23, 2021 · 50 likes · 8 shares · 1,190 followers View post →
Wee Lun Foo
@weelunfoo · X

de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysis @SportsMedicineJ Link: https://t.co/SepA4dWevT #buffer #exercise #supplement #nutrition https://t.co/WX0pRITRxu

Nov 28, 2021 · 47 likes · 19 shares · 812 followers View post →
Jozo Grgic
@Jozo_Grgic · X

Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysis https://t.co/tYOwbClo4I

Oct 23, 2021 · 35 likes · 7 shares · 5,467 followers View post →
Dr Lee Taylor PhD
@DrLeeTaylor · X

Great read in @SportsMedicineJ Extracellular Buffering Supplements to Improve Exercise Capacity & Performance: A Comprehensive Systematic Review & Meta-analysis https://t.co/mj1LBqnW1S @Bicycle_Bryan @luanaindaia @eimeardol @PaulSwinton9 @Artioli_Gui @LarsMcnaughton https://t.co/PUGKmswkRu

Oct 25, 2021 · 20 likes · 6 shares · 3,048 followers View post →
Bryan Saunders
@Bicycle_Bryan · X

Conclusions: These buffering agents appear to be suitable supplements to improve exercise capacity and performance. Test during training to monitor side-effects. And read the full text here: https://t.co/8xhybW7skr @SportsMedicineJ

Oct 25, 2021 · 7 likes · 1,190 followers View post →
Rene Sugar
@renesugar · X

Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysis https://t.co/EPrlk1fsvb

Aug 26, 2024 · 1 like · 3,960 followers View post →

All mentions

Rene Sugar
@renesugar · X

https://t.co/EPrlk1fsvb "Extracellular buffering supplements generate large increases in blood bicarbonate concentration leading to positive overall effects on exercise, with sodium bicarbonate being most effective."

Aug 26, 2024 · 1 like · 3,960 followers View post →
Rene Sugar
@renesugar · X

Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysis https://t.co/EPrlk1fsvb

Aug 26, 2024 · 1 like · 3,960 followers View post →
Gary Tingley
@garytingley · X

Research: "Extracellular buffering supplements generate large increases in blood bicarbonate concentration leading to positive overall effects on exercise, with sodium bicarbonate being most effective." https://t.co/xix2oKXIzI #cyclingcoach #ResultsStartHere @TrainingPeaks https://t.co/S75PjLsuXw

May 20, 2023 · 4,145 followers View post →
Gary Tingley
@garytingley · X

Is Individualization of Sodium Bicarbonate Ingestion Based on Time to Peak Necessary? https://t.co/KhL5pb3XFe #cycling #coaching #cyclingcoach #ResultsStartHere @TrainingPeaks https://t.co/aop46iQwmW

Mar 25, 2023 · 4,145 followers View post →
Edoctor
@Edoctor03393607 · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Dec 2, 2021 · 19 shares · 35 followers View post →
Luana Oliveira
@luanaindaia · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Dec 1, 2021 · 19 shares · 234 followers View post →
Matthew Ellis
@MatthewLeeEllis · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 30, 2021 · 19 shares · 477 followers View post →
Pilar Gil
@pilimariagc · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 29, 2021 · 19 shares · 82 followers View post →
Sports Medicine
@SportsMedicineJ · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 29, 2021 · 19 shares · 53,682 followers View post →
¡Elige Moverte!
@EligeMoverte · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 17 followers View post →
Weldon
@Rocker75W · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 330 followers View post →
newfs
@newfxfs · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 3,280 followers View post →
Pedro L. Valenzuela
@pl_valenzuela · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 2,756 followers View post →
Bryan Saunders
@Bicycle_Bryan · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 1,190 followers View post →
nfteam
@nfteam3 · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 2,178 followers View post →
ReVelde(S) Con V de... Valor...(ES)
@ReVeldes_VdV · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 1,764 followers View post →
Dr Paul Swinton
@PaulSwinton9 · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 454 followers View post →
Eimear Dolan
@eimeardol · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 677 followers View post →
Darren Delaney, MSc ASCC
@DarDelFitness · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 371 followers View post →
#NatureIsTheCure #ImmunesHealth
@natisthecure3 · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 2,767 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @wlf0503: de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Sy…

Nov 28, 2021 · 19 shares · 6,712 followers View post →
Wee Lun Foo
@weelunfoo · X

de Oliveira et al. (2021) Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysis @SportsMedicineJ Link: https://t.co/SepA4dWevT #buffer #exercise #supplement #nutrition https://t.co/WX0pRITRxu

Nov 28, 2021 · 47 likes · 19 shares · 812 followers View post →
Nutr Reviews
@NutrReview · X

Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysis https://t.co/kJDnnbVKaY

Oct 26, 2021 · 226 followers View post →
Murray Sheath
@Muzzer321 · X

RT @DrLeeTaylor: Great read in @SportsMedicineJ Extracellular Buffering Supplements to Improve Exercise Capacity & Performance: A Comprehe…

Oct 25, 2021 · 6 shares · 132 followers View post →
Bryan Saunders
@Bicycle_Bryan · X

Conclusions: These buffering agents appear to be suitable supplements to improve exercise capacity and performance. Test during training to monitor side-effects. And read the full text here: https://t.co/8xhybW7skr @SportsMedicineJ

Oct 25, 2021 · 7 likes · 1,190 followers View post →
Jacob Nelson
@athletejnelson · X

RT @DrLeeTaylor: Great read in @SportsMedicineJ Extracellular Buffering Supplements to Improve Exercise Capacity & Performance: A Comprehe…

Oct 25, 2021 · 6 shares · 26 followers View post →
Dr Paul Swinton
@PaulSwinton9 · X

RT @DrLeeTaylor: Great read in @SportsMedicineJ Extracellular Buffering Supplements to Improve Exercise Capacity & Performance: A Comprehe…

Oct 25, 2021 · 6 shares · 454 followers View post →
nick owen
@nickowen5 · X

RT @DrLeeTaylor: Great read in @SportsMedicineJ Extracellular Buffering Supplements to Improve Exercise Capacity & Performance: A Comprehe…

Oct 25, 2021 · 6 shares · 598 followers View post →
Jamie Stanley PhD
@jamiestanley85 · X

RT @DrLeeTaylor: Great read in @SportsMedicineJ Extracellular Buffering Supplements to Improve Exercise Capacity & Performance: A Comprehe…

Oct 25, 2021 · 6 shares · 2,801 followers View post →
Dr Lee Taylor PhD
@DrLeeTaylor · X

Great read in @SportsMedicineJ Extracellular Buffering Supplements to Improve Exercise Capacity & Performance: A Comprehensive Systematic Review & Meta-analysis https://t.co/mj1LBqnW1S @Bicycle_Bryan @luanaindaia @eimeardol @PaulSwinton9 @Artioli_Gui @LarsMcnaughton https://t.co/PUGKmswkRu

Oct 25, 2021 · 20 likes · 6 shares · 3,048 followers View post →
Dr. Myohead
@DrMyohead · X

RT @Bicycle_Bryan: An idea that started out four years ago, nice to see it come to fruition. Will post a thread on the main outcomes next w…

Oct 24, 2021 · 8 shares · 2,644 followers View post →
OJSN
@iamojsn · X

RT @Jozo_Grgic: Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Met…

Oct 24, 2021 · 7 shares · 14,988 followers View post →
Virginia Santesteban
@virginiasanmor3 · X

RT @Bicycle_Bryan: An idea that started out four years ago, nice to see it come to fruition. Will post a thread on the main outcomes next w…

Oct 24, 2021 · 8 shares · 449 followers View post →
Sandro F. da Silva
@sandrofersilva · X

RT @Jozo_Grgic: Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Met…

Oct 23, 2021 · 7 shares · 554 followers View post →
Alex James Welburn
@Alex_Welburn · X

RT @Bicycle_Bryan: An idea that started out four years ago, nice to see it come to fruition. Will post a thread on the main outcomes next w…

Oct 23, 2021 · 8 shares · 1,316 followers View post →
Nutricionistajuanquintero
@NutricionistaJQ · X

RT @Jozo_Grgic: Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Met…

Oct 23, 2021 · 7 shares · 41 followers View post →
Alex Romero
@alexromerocab · X

RT @Jozo_Grgic: Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Met…

Oct 23, 2021 · 7 shares · 1,723 followers View post →
Douglas Kalman PhD
@dougkalmanphdrd · X

RT @Jozo_Grgic: Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Met…

Oct 23, 2021 · 7 shares · 5,452 followers View post →
Luana Oliveira
@luanaindaia · X

RT @Bicycle_Bryan: An idea that started out four years ago, nice to see it come to fruition. Will post a thread on the main outcomes next w…

Oct 23, 2021 · 8 shares · 234 followers View post →
Jason Siegler
@jason_siegler · X

RT @Bicycle_Bryan: An idea that started out four years ago, nice to see it come to fruition. Will post a thread on the main outcomes next w…

Oct 23, 2021 · 8 shares · 414 followers View post →
Dr Paul Swinton
@PaulSwinton9 · X

RT @Bicycle_Bryan: An idea that started out four years ago, nice to see it come to fruition. Will post a thread on the main outcomes next w…

Oct 23, 2021 · 8 shares · 454 followers View post →
guzmannutrition
@guzmannutrition · X

RT @Bicycle_Bryan: An idea that started out four years ago, nice to see it come to fruition. Will post a thread on the main outcomes next w…

Oct 23, 2021 · 8 shares · 6,203 followers View post →
Matt Jones
@MattJonesNC · X

RT @Bicycle_Bryan: An idea that started out four years ago, nice to see it come to fruition. Will post a thread on the main outcomes next w…

Oct 23, 2021 · 8 shares · 3,558 followers View post →
Bryan Saunders
@Bicycle_Bryan · X

An idea that started out four years ago, nice to see it come to fruition. Will post a thread on the main outcomes next week @luanaindaia @eimeardol @PaulSwinton9 @Artioli_Gui @LarsMcnaughton https://t.co/kC0ZnQB6QI

Oct 23, 2021 · 50 likes · 8 shares · 1,190 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @drjohnmorley: de Oliveira, L.F., Dolan, E., Swinton, P.A. et al. Extracellular Buffering Supplements to Improve Exercise Capacity and P…

Oct 23, 2021 · 1 share · 6,712 followers View post →
Abramo coach
@coach_abramo · X

RT @Jozo_Grgic: Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Met…

Oct 23, 2021 · 7 shares · 74 followers View post →
john morley
@drjohnmorley · X

de Oliveira, L.F., Dolan, E., Swinton, P.A. et al. Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysis. Sports Med (2021). https://t.co/MQ5hYM0woa Download citation

Oct 23, 2021 · 1 share · 8,322 followers View post →
Jozo Grgic
@Jozo_Grgic · X

Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysis https://t.co/tYOwbClo4I

Oct 23, 2021 · 35 likes · 7 shares · 5,467 followers View post →