December 2021 PMID 34847226

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.

Mikael Fink Vallentin, Asger Granfeldt, Carsten Meilandt, Amalie Ling Povlsen, Birthe Sindberg, Mathias J Holmberg, Bo Nees Iversen, Rikke Mærkedahl, Lone Riis Mortensen, Rasmus Nyboe, Mads Partridge Vandborg, Maren Tarpgaard, Charlotte Runge, Christian Fynbo Christiansen, Thomas H Dissing

Mentions

173
Peak: 85 in Dec 2021
across 5 sources since Nov 2021

Extended reach

1,872,334
potential audience

Total likes

359

Video views

503

Mentions per month

Nov 2021 – May 2024

Where it's discussed

  • X / Twitter151 posts
  • Blogs10 articles
  • Facebook6 posts
  • News4 articles
  • YouTube2 videos

AI synopsis

What people are saying

Several discussions highlight key findings from the publication, mentioning that calcium administration did not improve return of spontaneous circulation, with phrases like 'no role for routine calcium' and 'administration may actually be harmful.' The tone reflects a serious consideration of the implications for emergency procedures, reinforcing the urgency to reassess current practices around calcium use in cardiac arrest scenarios.

AgreementModerate agreement

A majority of the discussions support the overall findings of the study, though some express skepticism regarding calcium's role.

InterestHigh interest

Posts show a high level of curiosity, with users actively referencing the study and discussing its implications.

EngagementModerate engagement

Many discussions dive into specific aspects and implications of the study, indicating a moderate level of engagement.

ImpactHigh impact

Users perceive the study's findings as having significant implications for emergency medicine practices.

Abstract in brief

  • The study aimed to assess whether administering calcium during out-of-hospital cardiac arrest would improve rates of return of spontaneous circulation compared to saline.
  • A total of 397 adult patients participated, with 197 receiving calcium and 200 receiving saline; the trial was stopped early due to safety concerns related to calcium use.
  • Results showed that fewer patients in the calcium group achieved spontaneous circulation (19 vs. 27) and had lower survival rates at 30 days compared to the saline group, indicating no significant benefit from calcium administration.

Top posts

Most liked on X and Bluesky
Anand Swaminathan MD MPH
@EMSwami · X

Quick breakdown of COCA Trial: IV/IO Ca vs Saline in OHCA https://t.co/Jx9FbtQoGo Bottom Line: -Calcium shouldn't be empirically given in OHCA -Continue to give Calcium for suspected hyperkalemic arrest (pts excluded from study) https://t.co/lqJRSyI2an

Dec 1, 2021 · 45 likes · 8 shares · 35,538 followers View post →
Daniel Jafari
@DanielJafari · X

I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, since their supplement one is essentially a review article and methodology rolled into one! https://t.co/8n3JcwWchU

Dec 4, 2021 · 41 likes · 9 shares · 2,186 followers View post →
Konstantin Krychtiuk
@krychtiukmd · X

Does calcium have beneficial effects in cardiac arrest patients? Short answer: No Rationale: Possible inotropic, vasopressor and cell membrane stabilizing effects. The Calcium in Out Of Hospital Cardiac Arrest Trial published in @JAMA_current https://t.co/VA2kMnLXgS https://t.co/x04JZpLDTh

Dec 6, 2021 · 28 likes · 5 shares · 6,300 followers View post →
Anand Swaminathan MD MPH
@EMSwami · X

No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-statistically sig) COCA 1 yr f/u https://t.co/qZphtTrw6p: survival + survival w/ good neuro outcome both worse w/ Ca2+ https://t.co/aaPVcJl66O

Aug 7, 2022 · 24 likes · 10 shares · 35,538 followers View post →
Sam Ghali, M.D.
@EM_RESUS · X

@georgoff @PulmCrit @emcrit @precordialthump @smaccteam @docmartin22 @elliotthaut @TraumaDocSF @TopKniFe_B Not routinely but low threshold if any inkling of ↑K+—which is really the only scenario where it will truly help. Here’s an interesting recent RCT on your question but for out-of-hospital cardiac arrest. https://t.co/LtR5kqj4pL

Jan 17, 2023 · 23 likes · 1 share · 653,278 followers View post →
Kevin Mercer, PharmD, MPH
@ohsnapimginger · X

Sexy Vallentin MF, Granfeldt A, Meilandt C, et al. Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial. JAMA. 2021;326(22):2268-2276. doi:10.1001/jama.2021.20929 https://t.co/8WwpAlUcCh

Oct 23, 2022 · 16 likes · 3,172 followers View post →

All mentions

Adrienne Perotti
@atp1202 · X

@PropofolDreamz @GDerevenskikh @ResuscAcademy I think people need to get up to date with the data. The study also did a post analysis in pts who had hyperkalemia and found it also to do nothing. This is excluding trauma, which is not ACLS. It is ATLS. https://t.co/7tkw5ct31e

Jan 26, 2024 · 2 likes · 99 followers View post →
Rafael Eduardo Herrera Elizalde
@RafaHerreraACV · X

Jan 23, 2024 · 1 like · 7,229 followers View post →
CALS-Latinoamérica
@CSUALSMexico · X

Jan 7, 2024 · 459 followers View post →
Rafael Eduardo Herrera Elizalde
@RafaHerreraACV · X

Jan 7, 2024 · 7,229 followers View post →
Josh Davis
@MedFactChecks · X

@blondemedSJW @PropofolDreamz Except increased mortality!! https://t.co/npzJGFLwXA

Oct 4, 2023 · 4 likes · 683 followers View post →
CCSIHCA
@CCsalud_Ing_Hum · X

RT @UrgenciologosMX: Las administración de calcio durante el paro cardíaco extrahospitalario en pacientes no seleccionados NO mejora el res…

Aug 17, 2023 · 2 shares · 52 followers View post →
Leonardo Soto Muñoz
@LeonardoSotoMu · X

Calcio IV/IO pre hospitalario en PCR no estadísticamente significativo versus SF https://t.co/cmKG3TjDG8

Jul 31, 2023 · 8,533 followers View post →
Manish Garg
@TheGargFather · X

RT @probstMD: Such a pleasure to connect with NYP students, residents, and faculty for Journal Club last night. On a rooftop terrace, no le…

Jul 29, 2023 · 3 shares · 713 followers View post →
Columbia Emergency Medicine
@ColumbiaEM · X

RT @probstMD: Such a pleasure to connect with NYP students, residents, and faculty for Journal Club last night. On a rooftop terrace, no le…

Jul 27, 2023 · 3 shares · 3,464 followers View post →
Marc Probst
@probstMD · X

Such a pleasure to connect with NYP students, residents, and faculty for Journal Club last night. On a rooftop terrace, no less. @ColumbiaEM @NYEmergency Great discussion about the COCA trial looking at calcium for OHCA. https://t.co/XD7O4vt2GU

Jul 27, 2023 · 14 likes · 3 shares · 961 followers View post →
Leif Rognås
@LeifRognas · X

@ktcollopy https://t.co/4Mf3qZaeLI

Apr 19, 2023 · 860 followers View post →
Henry Ajzenberg
@ajz_henry · X

@georgoff @PulmCrit @EM_RESUS @emcrit @precordialthump @smaccteam @docmartin22 @elliotthaut @TraumaDocSF @TopKniFe_B Recently studied in OHCA. In all comers, don't do it. https://t.co/K0xWFH1InV.

Jan 17, 2023 · 2 likes · 402 followers View post →
Patrick Georgoff, MD
@georgoff · X

RT @EM_RESUS: @georgoff @PulmCrit @emcrit @precordialthump @smaccteam @docmartin22 @elliotthaut @TraumaDocSF @TopKniFe_B Not routinely but…

Jan 17, 2023 · 1 share · 4,951 followers View post →
Sam Ghali, M.D.
@EM_RESUS · X

@georgoff @PulmCrit @emcrit @precordialthump @smaccteam @docmartin22 @elliotthaut @TraumaDocSF @TopKniFe_B Not routinely but low threshold if any inkling of ↑K+—which is really the only scenario where it will truly help. Here’s an interesting recent RCT on your question but for out-of-hospital cardiac arrest. https://t.co/LtR5kqj4pL

Jan 17, 2023 · 23 likes · 1 share · 653,278 followers View post →
AzPA
@azpharmacy · X

Learn More about today's Evidence Update HERE: https://t.co/4lQoqz6bTS #todayilearned https://t.co/1zwavoWldo

Nov 14, 2022 · 944 followers View post →
Kevin Mercer, PharmD, MPH
@ohsnapimginger · X

Sexy Vallentin MF, Granfeldt A, Meilandt C, et al. Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial. JAMA. 2021;326(22):2268-2276. doi:10.1001/jama.2021.20929 https://t.co/8WwpAlUcCh

Oct 23, 2022 · 16 likes · 3,172 followers View post →
Kilian (he/him)
@primumnokillem · X

RT @Luca_Uenlue: @doc_emed - COCA: https://t.co/4ZrSEjasYo - HyperK Brady Übersicht: https://t.co/yGBLAdBmqY - Tamponade im Echo: https://…

Aug 28, 2022 · 1 share · 100 followers View post →
Luca Ünlü
@Luca_Uenlue · X

@doc_emed - COCA: https://t.co/4ZrSEjasYo - HyperK Brady Übersicht: https://t.co/yGBLAdBmqY - Tamponade im Echo: https://t.co/CfLXslcMoR - Pads Position bei VHF CV: https://t.co/vmrbSqXU7A - TTM: https://t.co/zoe3ACIJ3A - Hands-on Defi: https://t.co/WsLOqJTVC9

Aug 27, 2022 · 5 likes · 1 share · 1,747 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @EMSwami: No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-…

Aug 9, 2022 · 10 shares · 6,923 followers View post →
Sobia Ambreen
@SobiaAmbreen5 · X

RT @EMSwami: No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-…

Aug 8, 2022 · 10 shares · 47 followers View post →
PacoCampillo
@PacoCampilloPal · X

RT @EMSwami: No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-…

Aug 8, 2022 · 10 shares · 274 followers View post →
mike defilippo
@MDtheDO · X

RT @EMSwami: No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-…

Aug 8, 2022 · 10 shares · 975 followers View post →
Roberto E Lopez Mata
@relm_11969 · X

RT @EMSwami: No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-…

Aug 8, 2022 · 10 shares · 1,140 followers View post →
James C. Fletcher, MD
@jfletchermd · X

RT @EMSwami: No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-…

Aug 8, 2022 · 10 shares · 1,420 followers View post →
Manrique Umana McDermott
@umanamd · X

RT @EMSwami: No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-…

Aug 8, 2022 · 10 shares · 12,109 followers View post →
Alexis Koda
@ar_koda · X

RT @EMSwami: No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-…

Aug 8, 2022 · 10 shares · 33 followers View post →
AB
@alsugairmd · X

RT @EMSwami: No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-…

Aug 8, 2022 · 10 shares · 37 followers View post →
Luca Ünlü
@Luca_Uenlue · X

RT @EMSwami: No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-…

Aug 7, 2022 · 10 shares · 1,747 followers View post →
Anand Swaminathan MD MPH
@EMSwami · X

No role for routine Ca2+ in cardiac arrest COCA https://t.co/Jx9FbtQoGo: ROSC higher in placebo group (27% vs 19% barely non-statistically sig) COCA 1 yr f/u https://t.co/qZphtTrw6p: survival + survival w/ good neuro outcome both worse w/ Ca2+ https://t.co/aaPVcJl66O

Aug 7, 2022 · 24 likes · 10 shares · 35,538 followers View post →
greysecond
@Greysecond · X

@fenlandgent “Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest A Randomized Clinical Trial Mikael Fink Vallentin, MD1; Asger Granfeldt, MD, PhD, DMSc2; Carsten Meilandt, BSc1; et al”

Jul 27, 2022 · 1 like · 276 followers View post →
Faith Komagum MD
@Fae_Mara · X

RT @AnaesthesiaMak: The weekly Journal Club is ongoing at the department of Anaesthesia and Critical Care. Today’s topic is the Effect of…

Jul 15, 2022 · 6 shares · 443 followers View post →
PICO
@PicoNyeko · X

RT @AnaesthesiaMak: The weekly Journal Club is ongoing at the department of Anaesthesia and Critical Care. Today’s topic is the Effect of…

Jul 15, 2022 · 6 shares · 3,930 followers View post →
Association of Anesthesiologists of Uganda
@AnesthesiaUg · X

RT @AnaesthesiaMak: The weekly Journal Club is ongoing at the department of Anaesthesia and Critical Care. Today’s topic is the Effect of…

Jul 15, 2022 · 6 shares · 5,253 followers View post →
Céline Jacobs
@_charliejuliet_ · X

RT @AnaesthesiaMak: The weekly Journal Club is ongoing at the department of Anaesthesia and Critical Care. Today’s topic is the Effect of…

Jul 15, 2022 · 6 shares · 628 followers View post →
Ronald Bisegerwa
@RonaldBisegerwa · X

RT @AnaesthesiaMak: The weekly Journal Club is ongoing at the department of Anaesthesia and Critical Care. Today’s topic is the Effect of…

Jul 15, 2022 · 6 shares · 1,221 followers View post →
Gemini_❤️
@grace_gitta · X

RT @AnaesthesiaMak: The weekly Journal Club is ongoing at the department of Anaesthesia and Critical Care. Today’s topic is the Effect of…

Jul 15, 2022 · 6 shares · 1,499 followers View post →
Mak Anaesthesia/Critical Care
@AnaesthesiaMak · X

The weekly Journal Club is ongoing at the department of Anaesthesia and Critical Care. Today’s topic is the Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest. A Randomized Clinical Trial. https://t.co/ETNprciueK

Jul 15, 2022 · 16 likes · 6 shares · 2,286 followers View post →
Mateusz Zawadka
@m_zawadka · X

https://t.co/KE2aeLqylB

Jun 17, 2022 · 1,519 followers View post →
Critical Care Talk
@NWCriticalCare · X

#CCR2 #COCAtrial Time to discuss another Denmark Trial - calcium in Cardiac arrest. We start off by underlying the poor outcomes when our heart stops - 90% mortality https://t.co/2XxRbqmfFE

Jun 17, 2022 · 792 followers View post →
Dr Linda Dykes has moved to Bluesky
@DrLindaDykes · X

RT @BMorshediMD: 3) Should we routinely use calcium in cardiac arrest? Historically, the studies supporting it rarely support ROSC and sur…

Jun 16, 2022 · 2 shares · 31,841 followers View post →
Eagles Coalition
@EaglesGather · X

RT @BMorshediMD: 3) Should we routinely use calcium in cardiac arrest? Historically, the studies supporting it rarely support ROSC and sur…

Jun 16, 2022 · 2 shares · 2,744 followers View post →
Brandon Morshedi, MD, DPT, FACEP, FAEMS
@BMorshediMD · X

3) Should we routinely use calcium in cardiac arrest? Historically, the studies supporting it rarely support ROSC and survival and only about 70% of them are even human trials! So, enter a double-blinded, placebo study done with EMS! https://t.co/BihLe4G3MS #GatheringEagles22

Jun 16, 2022 · 4 likes · 2 shares · 2,584 followers View post →
Research Center for Emergency Medicine
@RECEM_CFA · X

1⃣ @LarsWAndersen1 is nominated in the category of investigator-initiated trials.

May 31, 2022 · 2 likes · 171 followers View post →
ResusBot
@Resus_Bot · X

RT @AlhussainiZ: Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospita…

May 10, 2022 · 1 share · 181 followers View post →
Zainab
@AlhussainiZ · X

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest A Randomized Clinical Trial #OHCA #EMS #FOAMed https://t.co/kuLf4uYyKx via @JAMA_current part of @JAMANetwork

May 10, 2022 · 2 likes · 1 share · 843 followers View post →
Giovanni Landoni, MD
@giovannilandoni · X

@reverendofdoubt https://t.co/DZbjmUMqeC

Mar 14, 2022 · 1 like · 4,690 followers View post →
Giovanni Landoni, MD
@giovannilandoni · X

@IdiotTracker @reverendofdoubt https://t.co/DZbjmUMqeC

Mar 14, 2022 · 2 likes · 4,690 followers View post →
Dr. Oceane MINKA
@MinkaOceane_Dr · X

RT @MinkaHillary: Cet ECR a montré qu'une injection de calcium comparée au placébo est délétère sur la récupération d'une activité cardiaqu…

Feb 13, 2022 · 1 share · 4,081 followers View post →
Dr Hillary MINKA
@MinkaHillary · X

Cet ECR a montré qu'une injection de calcium comparée au placébo est délétère sur la récupération d'une activité cardiaque spontanée et la survie à J30 après un ACR pré hospitalier non traumatique de l'adulte. L'étude a été interrompue précocement !!! https://t.co/gZBQpNzgcA https://t.co/YmCivbLGLB

Feb 13, 2022 · 2 likes · 1 share · 1,744 followers View post →
UGAC3
@ugac3 · X

A trial recently published in @JAMA_current looked at the role of calcium vs. placebo on ROSC for patients with out-of-hospital cardiac arrest. They found that no significant improvement was seen. Check out more below! @knguyen252 #TwitteRx https://t.co/6nS5mWbZmC https://t.co/o2n4ScbuG1

Jan 17, 2022 · 2 likes · 773 followers View post →
Joseph Zalkin #
@jzalkin · X

RT @CARESRegistry: Among adults with OHCA, treatment with intravenous or intraosseous calcium compared with saline did not significantly im…

Jan 15, 2022 · 1 share · 1,817 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @tscquizzato: 5/ The #COCA trial: IV or IO Calcium in OHCA Among adults with OHCA, treatment with intravenous or intraosseous calcium…

Jan 13, 2022 · 6 shares · 6,923 followers View post →
Danny Bolaños
@cholodelvado · X

#TheCOCATrial ENN #RCP extrahospitalaria, administrar #Calcio IV o IO no mejora el retorno a circulación espontánea. #foamed https://t.co/DsdFo3Wd5F

Jan 4, 2022 · 299 followers View post →
DASAIM
@DASAIMdk · X

RT @tscquizzato: 5/ The #COCA trial: IV or IO Calcium in OHCA Among adults with OHCA, treatment with intravenous or intraosseous calcium…

Jan 2, 2022 · 6 shares · 738 followers View post →
Ken Milne MD
@TheSGEM · X

Link to the article https://t.co/X9qhNXDENT

Dec 31, 2021 · 28,284 followers View post →
Justyna Swol MD • ECMOdaily
@ECMOdaily · X

RT @tscquizzato: 5/ The #COCA trial: IV or IO Calcium in OHCA Among adults with OHCA, treatment with intravenous or intraosseous calcium…

Dec 30, 2021 · 6 shares · 3,391 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @tscquizzato: 5/ The #COCA trial: IV or IO Calcium in OHCA Among adults with OHCA, treatment with intravenous or intraosseous calcium…

Dec 30, 2021 · 6 shares · 6,923 followers View post →
Tommaso Scquizzato, MD
@tscquizzato · X

RT @tscquizzato: 5/ The #COCA trial: IV or IO Calcium in OHCA Among adults with OHCA, treatment with intravenous or intraosseous calcium…

Dec 29, 2021 · 6 shares · 5,137 followers View post →
Cardiac Arrest Center - Ospedale San Raffaele
@SRCardiacArrest · X

RT @tscquizzato: 5/ The #COCA trial: IV or IO Calcium in OHCA Among adults with OHCA, treatment with intravenous or intraosseous calcium…

Dec 29, 2021 · 6 shares · 593 followers View post →
Tommaso Scquizzato, MD
@tscquizzato · X

5/ The #COCA trial: IV or IO Calcium in OHCA Among adults with OHCA, treatment with intravenous or intraosseous calcium compared with saline did not significantly improve sustained ROSC.

Dec 29, 2021 · 4 likes · 6 shares · 5,137 followers View post →
Ken Milne MD
@TheSGEM · X

Link to the COCA trial on calcium for OHCA published in @JAMA_current https://t.co/X9qhNXDENT

Dec 27, 2021 · 2 likes · 28,284 followers View post →
Ken Milne MD
@TheSGEM · X

Link to COCA trial published in @JAMA_current https://t.co/X9qhNXDENT

Dec 27, 2021 · 28,284 followers View post →
Ken Milne MD
@TheSGEM · X

Link to the RCT published in @JAMA_current that we reviewed on the SGEM-JC #EBM https://t.co/X9qhNXDENT

Dec 26, 2021 · 28,284 followers View post →
Pathway
@PathwayMedical · X

Dec 25, 2021 · 1 like · 13,044 followers View post →
Joseph Zalkin #
@jzalkin · X

RT @TheSGEM: Next up on the SGEM is this paper from @JAMA_current on Calcium for OHCA. Any guesses on theme music? https://t.co/X9qhNXDENT…

Dec 24, 2021 · 1 share · 1,817 followers View post →
Ken Milne MD
@TheSGEM · X

Next up on the SGEM is this paper from @JAMA_current on Calcium for OHCA. Any guesses on theme music? https://t.co/X9qhNXDENT @KirstyChallen @ffolliet @broomedocs @DrSimonMc

Dec 24, 2021 · 5 likes · 1 share · 28,284 followers View post →
Cardiac Arrest Registry to Enhance Survival (CARES
@CARESRegistry · X

Among adults with OHCA, treatment with intravenous or intraosseous calcium compared with saline did not significantly improve sustained return of spontaneous circulation. These results do not support the administration of calcium during OHCA in adults. https://t.co/iHXtqCVGIZ

Dec 16, 2021 · 5 likes · 1 share · 721 followers View post →
Ashley Schenk, PharmD, BCCP, AACC
@ASchenkPharmD · X

RT @CardiacRX: Dirty secret in medicine that ACLS minus a few things (compressions, early defib, possibly epinephrine) is more theatrical t…

Dec 14, 2021 · 1 share · 1,032 followers View post →
xxxichiroxxx_ID
@xxxichiroxxx_ID · X

RT @JAMA_current: RCT found treatment with intravenous or intraosseous calcium did not significantly improve return of spontaneous circulat…

Dec 14, 2021 · 4 shares · 157 followers View post →
Steven Dunn
@CardiacRX · X

Dirty secret in medicine that ACLS minus a few things (compressions, early defib, possibly epinephrine) is more theatrical than life saving. Code cart starting to get pretty slim: https://t.co/3LEz9tatEq

Dec 14, 2021 · 13 likes · 1 share · 1,097 followers View post →
Pub Health Monitor
@monitor_PH · X

RT @JAMA_current: RCT found treatment with intravenous or intraosseous calcium did not significantly improve return of spontaneous circulat…

Dec 14, 2021 · 4 shares · 1,824 followers View post →
JAMA
@JAMA_current · X

RCT found treatment with intravenous or intraosseous calcium did not significantly improve return of spontaneous circulation among adults with out-of-hospital cardiac arrest https://t.co/8Ul1jrWNwF

Dec 14, 2021 · 11 likes · 4 shares · 488,788 followers View post →
R. Jay Widmer
@DrArgyle · X

(No) Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation After Out-of-Hospital Cardiac Arrest https://t.co/1HSSlIsKx0 via @practiceupdate

Dec 12, 2021 · 1 like · 2,915 followers View post →
IANCARDIOLOGY
@CardioIAN · X

#CardioTwitter @CardioIAN https://t.co/APnEVgW60T

Dec 12, 2021 · 1 like · 8,261 followers View post →
Cardiology
@PracUpCardio · X

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation After Out-of-Hospital Cardiac Arrest https://t.co/sbp0Cab9HX #cardiology

Dec 12, 2021 · 2 likes · 880 followers View post →
Nao
@js6dmt · X

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-… https://t.co/B0eiBVyl8T

Dec 9, 2021 · 145 followers View post →
Dr. Jeffrey Le, D.O.
@drjeffle · X

RT @DanielJafari: I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, s…

Dec 7, 2021 · 9 shares · 753 followers View post →
Paramedic papers
@ParamedicPapers · X

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial https://t.co/DsZMqHjpP6

Dec 7, 2021 · 2,667 followers View post →
Alberto Cereda
@AlbertoCereda1 · X

JAMA. 2021 Nov 30. doi: 10.1001 jama.2021.20929. PMID: 34847226 https://t.co/qS03jHHk6B

Dec 7, 2021 · 4 likes · 4,679 followers View post →
Luis Figueroa
@LuisFig1706 · X

"Estos resultados no apoyan la administración de calcio durante un paro cardíaco extrahospitalario en adultos" Contrataron con resultados de aplicación de solución salina

Dec 6, 2021 · 44 followers View post →
Imran Sharieff
@sas_sobauk · X

RT @EMSwami: Quick breakdown of COCA Trial: IV/IO Ca vs Saline in OHCA https://t.co/Jx9FbtQoGo Bottom Line: -Calcium shouldn't be empirica…

Dec 6, 2021 · 8 shares · 1,290 followers View post →
Akhil
@akhilG83 · X

RT @EMSwami: Quick breakdown of COCA Trial: IV/IO Ca vs Saline in OHCA https://t.co/Jx9FbtQoGo Bottom Line: -Calcium shouldn't be empirica…

Dec 6, 2021 · 8 shares · 658 followers View post →
Emily Sharpe, MD, FASA
@emilysharpe · X

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest RCT in @JAMA_current IV/IO calcium did not significantly improve sustained ROSC in adults w/ cardiac arrest. https://t.co/1Et3tk4nAt https://t.co/F7ZNzb2ABU

Dec 6, 2021 · 7,656 followers View post →
Copenhagen Cardiovascular Research Center
@CopCard · X

RT @krychtiukmd: Does calcium have beneficial effects in cardiac arrest patients? Short answer: No Rationale: Possible inotropic, vasopre…

Dec 6, 2021 · 5 shares · 4,144 followers View post →
Dr Duncan Hogg
@drduncanhogg · X

RT @krychtiukmd: Does calcium have beneficial effects in cardiac arrest patients? Short answer: No Rationale: Possible inotropic, vasopre…

Dec 6, 2021 · 5 shares · 1,304 followers View post →
rafavidalperez
@rafavidalperez · X

RT @krychtiukmd: Does calcium have beneficial effects in cardiac arrest patients? Short answer: No Rationale: Possible inotropic, vasopre…

Dec 6, 2021 · 5 shares · 13,846 followers View post →
JB
@abd_jabbar · X

RT @krychtiukmd: Does calcium have beneficial effects in cardiac arrest patients? Short answer: No Rationale: Possible inotropic, vasopre…

Dec 6, 2021 · 5 shares · 4,483 followers View post →
Milica Aleksic
@drmilicaa · X

RT @krychtiukmd: Does calcium have beneficial effects in cardiac arrest patients? Short answer: No Rationale: Possible inotropic, vasopre…

Dec 6, 2021 · 5 shares · 1,296 followers View post →
Konstantin Krychtiuk
@krychtiukmd · X

Does calcium have beneficial effects in cardiac arrest patients? Short answer: No Rationale: Possible inotropic, vasopressor and cell membrane stabilizing effects. The Calcium in Out Of Hospital Cardiac Arrest Trial published in @JAMA_current https://t.co/VA2kMnLXgS https://t.co/x04JZpLDTh

Dec 6, 2021 · 28 likes · 5 shares · 6,300 followers View post →
Nicholas G Fitz
@nicholasgfitz · X

RT @DanielJafari: I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, s…

Dec 5, 2021 · 9 shares · 27 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @DanielJafari: I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, s…

Dec 4, 2021 · 9 shares · 6,923 followers View post →
pinacol
@pinacol · X

【RCT】院外心停止患者への塩化カルシウムの投与は、生食の投与と比較して、心拍再開率を改善させなかった。(カルシウム投与の害の懸念により早期中止) #ペ読 https://t.co/N4vgJUNdfg

Dec 4, 2021 · 2 likes · 1,615 followers View post →
Alex Estrella
@alexjestrella · X

RT @DanielJafari: I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, s…

Dec 4, 2021 · 9 shares · 3,255 followers View post →
David A. Marcus, MD
@EMIMDoc · X

RT @DanielJafari: I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, s…

Dec 4, 2021 · 9 shares · 7,008 followers View post →
Raghu Venugopal MD
@raghu_venugopal · X

RT @petrosoniak: Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospita…

Dec 4, 2021 · 3 shares · 15,526 followers View post →
Greywolf
@Graywol99982773 · X

RT @petrosoniak: Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospita…

Dec 4, 2021 · 3 shares · 193 followers View post →
Andrew Petrosoniak
@petrosoniak · X

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial | Cardiology | JAMA | JAMA Network https://t.co/iE2fJlEIei

Dec 4, 2021 · 5 likes · 3 shares · 12,254 followers View post →
ACEP CCM Section
@acepccmsection · X

RT @DanielJafari: I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, s…

Dec 4, 2021 · 9 shares · 922 followers View post →
Alessandro Favaron, MD
@Alejandrofava · X

Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults https://t.co/fXRvdJfcsi via @JAMA_current part of @JAMANetwork

Dec 4, 2021 · 279 followers View post →
Ally M. Hynes, MD, FAAEM, FACEP
@GomerFoamER · X

RT @DanielJafari: I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, s…

Dec 4, 2021 · 9 shares · 1,811 followers View post →
Nick Johnson
@NickJohnsonMD · X

RT @DanielJafari: I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, s…

Dec 4, 2021 · 9 shares · 6,547 followers View post →
Mike Erdman
@erdapenum1 · X

Well I guess we can take Calcium out of the crash carts… https://t.co/36H62zb5oL

Dec 4, 2021 · 5 likes · 175 followers View post →
Nick Mark MD
@nickmmark · X

RT @DanielJafari: I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, s…

Dec 4, 2021 · 9 shares · 65,761 followers View post →
南郷 栄秀/Eishu NANGO, MD, PhD
@enango · X

デンマークでのRCTで,院外心停止の成人患者に対して,エピネフリン初回投与後の5mmolの塩化カルシウムの静脈内投与または骨内投与は,生理食塩液と比較して持続的な自然循環の回復を有意に改善しなかった. https://t.co/KHwtSXlvYL

Dec 4, 2021 · 1 like · 3,018 followers View post →
Daniel Jafari
@DanielJafari · X

I just finished reading the recent Danish RCT on Calcium in cardiac arrest. It's an amazing read, kudos to the authors, since their supplement one is essentially a review article and methodology rolled into one! https://t.co/8n3JcwWchU

Dec 4, 2021 · 41 likes · 9 shares · 2,186 followers View post →
simon laing
@laing_simon · X

#ncbi https://t.co/97Oo0yzcil

Dec 3, 2021 · 5,387 followers View post →
Distinguished Emeritus Prof Robyn A Clark
@clark_ra · X

RT @aus_roc: Treatment with IV or IO calcium did not significantly improve ROSC in adult OHCAs https://t.co/pBQmuwQ2Mh via @JAMA_current pa…

Dec 3, 2021 · 4 shares · 1,228 followers View post →
Guillermo Méndez
@Memo99373405 · X

RT @UrgenciologosMX: Las administración de calcio durante el paro cardíaco extrahospitalario en pacientes no seleccionados NO mejora el res…

Dec 2, 2021 · 2 shares · 269 followers View post →
ESO
@ESO_Solutions · X

Does Ca administration help or hurt in response to out-of-hospital cardiac arrest w/o a specific indication? A new study in @JAMA_current says routine Ca may be harmful. Data from the ESO Data Collaborative show Ca is administered less than 5% of the time. https://t.co/EvL7LViz5s

Dec 2, 2021 · 1 like · 1,421 followers View post →
@UrgenciólogosMX
@UrgenciologosMX · X

Las administración de calcio durante el paro cardíaco extrahospitalario en pacientes no seleccionados NO mejora el resultado, incluso puede ser perjudicial.

Dec 2, 2021 · 10 likes · 2 shares · 7,766 followers View post →
Carlos Fuentes
@carlhfuentes · X

RT @SystemEmergency: No aplicamos Calcio IV o IO en todo paciente en parada cardiaca, solo en aquellos con sospecha alta de hiperK o hipoCa…

Dec 2, 2021 · 2 shares · 58 followers View post →
Roberto E Lopez Mata
@relm_11969 · X

RT @SystemEmergency: No aplicamos Calcio IV o IO en todo paciente en parada cardiaca, solo en aquellos con sospecha alta de hiperK o hipoCa…

Dec 2, 2021 · 2 shares · 1,140 followers View post →
Emergency Global System
@SystemEmergency · X

No aplicamos Calcio IV o IO en todo paciente en parada cardiaca, solo en aquellos con sospecha alta de hiperK o hipoCa.. https://t.co/npJssaeszm

Dec 2, 2021 · 2 likes · 2 shares · 1,926 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @EMSwami: Quick breakdown of COCA Trial: IV/IO Ca vs Saline in OHCA https://t.co/Jx9FbtQoGo Bottom Line: -Calcium shouldn't be empirica…

Dec 2, 2021 · 8 shares · 6,923 followers View post →
Nick Jakowenko
@Jick_Nakowenko · X

COCA trial showed no benefit of empiric intravenous calcium in OHCA and was stopped early. Still think Ca may be appropriate if we know/suspect hyperK (more relevant to IHCA), but alas: early and solid compressions >> drugs: https://t.co/7RHC7bNB5W https://t.co/DnwZweo8Ed

Dec 2, 2021 · 1 like · 99 followers View post →
Prague ICU_Michal Pazdernik
@PragueICU · X

⚠️❤️

Dec 2, 2021 · 4,046 followers View post →
Manrique Umana McDermott
@umanamd · X

RT @EMSwami: Quick breakdown of COCA Trial: IV/IO Ca vs Saline in OHCA https://t.co/Jx9FbtQoGo Bottom Line: -Calcium shouldn't be empirica…

Dec 2, 2021 · 8 shares · 12,109 followers View post →
the paper link
@the_paper_link · X

RT @the_paper_link: Trend new: Vallentin MF, ..., Andersen LW (JAMA) __Effect of Intravenous or Intraosseous Calcium vs Saline on Return o…

Dec 2, 2021 · 1 share · 137 followers View post →
Physician Wall
@physicianwall · X

https://t.co/F4HOHPo3Xl

Dec 1, 2021 · 42 followers View post →
the paper link
@the_paper_link · X

Trend new: Vallentin MF, ..., Andersen LW (JAMA) __Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial__ https://t.co/M1Nu5aYwpi

Dec 1, 2021 · 1 share · 137 followers View post →
John Papadopoulos
@JPCritCarePharm · X

RT @TaniaAhuja: #COCAtrial ➡️ #calcium IV/IO for #OHCA #ROSC 19% CaCl2

Dec 1, 2021 · 1 share · 325 followers View post →
Valerie Pierre MD
@ValeriePierreMD · X

RT @EMSwami: Quick breakdown of COCA Trial: IV/IO Ca vs Saline in OHCA https://t.co/Jx9FbtQoGo Bottom Line: -Calcium shouldn't be empirica…

Dec 1, 2021 · 8 shares · 779 followers View post →
Tania Ahuja
@TaniaAhuja · X

#COCAtrial ➡️ #calcium IV/IO for #OHCA #ROSC 19% CaCl2

Dec 1, 2021 · 9 likes · 1 share · 1,038 followers View post →
PacoCampillo
@PacoCampilloPal · X

RT @EMSwami: Quick breakdown of COCA Trial: IV/IO Ca vs Saline in OHCA https://t.co/Jx9FbtQoGo Bottom Line: -Calcium shouldn't be empirica…

Dec 1, 2021 · 8 shares · 274 followers View post →
Dallas Holladay, DO (she/her)
@Dallas_Holladay · X

RT @EMSwami: Quick breakdown of COCA Trial: IV/IO Ca vs Saline in OHCA https://t.co/Jx9FbtQoGo Bottom Line: -Calcium shouldn't be empirica…

Dec 1, 2021 · 8 shares · 11,900 followers View post →
Anand Swaminathan MD MPH
@EMSwami · X

Quick breakdown of COCA Trial: IV/IO Ca vs Saline in OHCA https://t.co/Jx9FbtQoGo Bottom Line: -Calcium shouldn't be empirically given in OHCA -Continue to give Calcium for suspected hyperkalemic arrest (pts excluded from study) https://t.co/lqJRSyI2an

Dec 1, 2021 · 45 likes · 8 shares · 35,538 followers View post →
Arjun Arya, MD, MSc.
@aryadoctoryet · X

Fascinating. https://t.co/QS4xXne8Mr

Dec 1, 2021 · 2 likes · 2,996 followers View post →
Quintard hervé
@QuintardH · X

RT @anarlfasso: Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital…

Dec 1, 2021 · 2 shares · 161 followers View post →
Tom Quinn etc.
@proftomquinn · X

RT @mdonnino: Link to full article: https://t.co/FE3DKU3iAY

Dec 1, 2021 · 1 share · 5,631 followers View post →
Akshay Vijayaraman
@AkshayVijayara1 · X

RT @danleisman: Even when doing everything, still do as much nothing as possible. https://t.co/g13j1QThvV

Dec 1, 2021 · 3 shares · 1,057 followers View post →
Diane Dreucean
@RomanianPharmD · X

RT @CritCareReviews: Full text https://t.co/ddpsT3ZkCx @JAMA_current @LarsWAndersen1 @AarhusUni_int

Dec 1, 2021 · 7 shares · 211 followers View post →
Caumon Laurent
@CaumonL · X

Effet du calcium intraveineux ou intraosseux vs salin sur le retour de la circulation spontanée chez les adultes atteints d'arrêt cardiaque hors hôpital : un essai clinique randomisé | Cardiologie | JAMA | Réseau JAMA https://t.co/FlJWByNDpM

Dec 1, 2021 · 72 followers View post →
H. Bassama
@HBanesth · X

RT @anarlfasso: Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital…

Dec 1, 2021 · 2 shares · 122 followers View post →
@investigando
@rocatanho · X

En adultos c/paro cardíaco extrahospitalario, el calcio IV o intraóseo no mejora significativamente el retorno sostenido de la circulación espontánea, por lo que no tiene sentido administrar calcio https://t.co/XO5a3LXihp a través de @JAMA_current part of @JAMANetwork

Dec 1, 2021 · 400 followers View post →
Italo Kumamoto
@fikkumamoto · X

RT @gbiondizoccai: "Among adults with out-of-hospital cardiac arrest, treatment with intravenous or intraosseous calcium compared with sali…

Dec 1, 2021 · 1 share · 8,804 followers View post →
Giuseppe Biondi-Zoccai
@gbiondizoccai · X

"Among adults with out-of-hospital cardiac arrest, treatment with intravenous or intraosseous calcium compared with saline did not significantly improve sustained return of spontaneous circulation" https://t.co/QqPYWl6mzB

Dec 1, 2021 · 3 likes · 1 share · 12,170 followers View post →
ANARLF
@anarlfasso · X

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial | Cardiology | JAMA | JAMA Network https://t.co/tEpVJc74oM

Dec 1, 2021 · 3 likes · 2 shares · 1,228 followers View post →
Gac Ciencia Forense
@GacetaCienForen · X

https://t.co/LPDC84hV2H

Dec 1, 2021 · 1,523 followers View post →
つぼこむ@兼業投資家(日本株+インデックス投信)
@Katsura_ERxCCM · X

塩化カルシウム5mmolをエピネフリン投与後に静注・骨髄注しても自己心拍再開率に有意差無し、というRCT報告。用量、回数などの問題あるか。安価な薬剤であり、今後用法用量が適正化され有意差が出れば使用してみる価値はあるのかも。今はまだその立ち位置ではない。 https://t.co/dimuEknVPz

Dec 1, 2021 · 185 followers View post →
Joshua Denson MD
@jdensonMD · X

I am surprised by these data. I don’t use calcium routinely in cardiac arrest, but anecdotally I have seen it reverse florid shock/achieve rosc in the icu at times Calcium vs Saline on Return of Spontaneous Circulation in Adults https://t.co/ZqMWlTy4Hg @JAMA_current @JAMANetwork

Nov 30, 2021 · 1,152 followers View post →
Or Bruck, DO
@OrBrDO · X

RT @danleisman: Even when doing everything, still do as much nothing as possible. https://t.co/g13j1QThvV

Nov 30, 2021 · 3 shares · 100 followers View post →
Jürgen Knapp
@anaesthemergmed · X

https://t.co/ARvXnFx7OU

Nov 30, 2021 · 2 likes · 1,901 followers View post →
Matt Siuba
@msiuba · X

RT @danleisman: Even when doing everything, still do as much nothing as possible. https://t.co/g13j1QThvV

Nov 30, 2021 · 3 shares · 16,967 followers View post →
Dan Leisman, MD, MSCR
@danleisman · X

Even when doing everything, still do as much nothing as possible. https://t.co/g13j1QThvV

Nov 30, 2021 · 16 likes · 3 shares · 2,547 followers View post →
Simon Craig
@DrSimonCraig · X

RT @aus_roc: Treatment with IV or IO calcium did not significantly improve ROSC in adult OHCAs https://t.co/pBQmuwQ2Mh via @JAMA_current pa…

Nov 30, 2021 · 4 shares · 1,996 followers View post →
Nate Haas
@Nate__Haas · X

RT @JAMA_current: RCT found treatment with intravenous or intraosseous calcium did not significantly improve return of spontaneous circulat…

Nov 30, 2021 · 27 shares · 512 followers View post →
JL Gabzenn
@NephCCM · X

Wow https://t.co/rCgR3Q6DPD

Nov 30, 2021 · 3,776 followers View post →
moleskine
@moleskine8 · X

RT @expensivecare: RCT of IV/IO calcium in OHCA stopped early by safety committee due to concerns about increased mortality in those who re…

Nov 30, 2021 · 30 shares · 511 followers View post →
Brian Burns
@HawkmoonHEMS · X

RT @JAMA_current: RCT found treatment with intravenous or intraosseous calcium did not significantly improve return of spontaneous circulat…

Nov 30, 2021 · 27 shares · 7,884 followers View post →
Brian Burns
@HawkmoonHEMS · X

RT @JAMA_current: RCT found treatment with intravenous or intraosseous calcium did not significantly improve return of spontaneous circulat…

Nov 30, 2021 · 5 shares · 7,884 followers View post →
Kam Ghadimi
@KamGhadimiMD · X

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial | ⁦@JAMA_current⁩ | ⁦@JAMANetwork⁩ https://t.co/rfA97w70I3

Nov 30, 2021 · 1 like · 1,375 followers View post →