Front Oncol November 2021 PMID 34858832

Vitamin K2 Inhibits Hepatocellular Carcinoma Cell Proliferation by Binding to 17β-Hydroxysteroid Dehydrogenase 4.

Xin Lu, Panpan Ma, Lingyu Kong, Xi Wang, Yaqi Wang, Lingling Jiang

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Mentions

16
Peak: 10 in Nov 2024
across 3 sources since Nov 2021

Extended reach

147,532
potential audience

Total likes

2,948

Video views

69,914

Mentions per month

Nov 2021 – Nov 2025

Where it's discussed

  • X / Twitter13 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions revolve around the promising role of Vitamin K2 in cancer inhibition, exemplified by statements like 'Vitamin K2 stops the division of cancer cells' and questions about its broader health benefits. The tone is cautiously optimistic, emphasizing scientific results and potential applications, which reflects a moderate level of engagement and interest in the research's impact.

AgreementModerate agreement

Most posts seem to support the article's findings that Vitamin K2 can play a role in inhibiting liver cancer cell growth.

InterestModerate interest

Discussion and comments show moderate curiosity, with statements like 'K2 kills cancer' indicating some enthusiasm, but not overwhelmingly so.

EngagementModerate engagement

Users participate by sharing interpretations and discussing implications, such as questioning if Vitamin K2 might be a missing link for better health.

ImpactModerate impact

The reactions suggest the research has potential significance for health and cancer prevention, with terms like 'new research' and references to 'stopping cancer' highlighting its possible importance.

Abstract in brief

  • Vitamin K2 (VK2) can bind directly to the protein HSD17B4, which promotes the growth of liver cancer cells (HCC).
  • VK2 inhibits HCC cell proliferation by blocking the activation of specific signaling pathways (Akt, MEK-ERK, and STAT3) without changing HSD17B4 levels.
  • The study found that VK2 also reduces tumor growth in animal models, suggesting its potential use in preventing or treating liver cancer.

Top posts

Most liked on X and Bluesky
Chris Milbank
@ChrisMilbank · X

Vitamin k2 stops the division of cancer cells, therefore growth of cancer. Is Vitamin K2 the Missing Link for Better Health? https://t.co/AQgnK9IUDm via @YouTube

Nov 23, 2024 · 2 likes · 45,821 followers View post →
Michael Henry
@MichaelHen26343 · X

Nov 21, 2024 · 1 like · 1 share · 81 followers View post →
sal
@tevet · X

Dec 28, 2024 · 8,327 followers View post →
Frontiers - Oncology
@FrontOncology · X

New research: Vitamin K2 Inhibits Hepatocellular Carcinoma Cell Proliferation by Binding to 17β-Hydroxysteroid Dehydrogenase 4: Our previous studies have proved that 17β-hydroxysteroid dehydrogenase 4 (HSD17B4) is a novel… https://t.co/2a08317WWg #oncology

Nov 9, 2021 · 6,509 followers View post →
George Ohwell
@GeorgeO_1984 · X

Nov 18, 2024 · 6,009 followers View post →
luis hernan graffe
@hernangraffe · X

RT @hernangraffe: https://t.co/AlhewUJQM8

Nov 21, 2024 · 1 share · 3,111 followers View post →

All mentions

Andrew Lipham
@AndrewLipham36 · X

Nov 8, 2025 · 74 followers View post →
0HMS0
@0HMS0 · X

https://t.co/E5LCr8t5yI

Apr 11, 2025 · 931 followers View post →
Paul Anderson
@PaulAnd37621913 · X

Jan 27, 2025 · 1,716 followers View post →
sal
@tevet · X

Dec 28, 2024 · 8,327 followers View post →
helpyougetgains.bsky.social
@helpyougetgains.bsky.social · Bluesky

Nov 27, 2024 View post →
Gary T. Sottile
@GPZO · X

Nov 23, 2024 · 1,060 followers View post →
Chris Milbank
@ChrisMilbank · X

Vitamin k2 stops the division of cancer cells, therefore growth of cancer. Is Vitamin K2 the Missing Link for Better Health? https://t.co/AQgnK9IUDm via @YouTube

Nov 23, 2024 · 2 likes · 45,821 followers View post →
Wolfey102
@Wolfey102 · X

K2 kills cancer.

Nov 22, 2024 · 685 followers View post →
luis hernan graffe
@hernangraffe · X

RT @hernangraffe: https://t.co/AlhewUJQM8

Nov 21, 2024 · 1 share · 3,111 followers View post →
Michael Henry
@MichaelHen26343 · X

Nov 21, 2024 · 1 like · 1 share · 81 followers View post →
luis hernan graffe
@hernangraffe · X

https://t.co/AlhewUJQM8

Nov 20, 2024 · 1 share · 3,111 followers View post →
George Ohwell
@GeorgeO_1984 · X

Nov 18, 2024 · 6,009 followers View post →
howard1972
@howard19721 · X

Nov 17, 2024 · 178 followers View post →
Frontiers - Oncology
@FrontOncology · X

New research: Vitamin K2 Inhibits Hepatocellular Carcinoma Cell Proliferation by Binding to 17β-Hydroxysteroid Dehydrogenase 4: Our previous studies have proved that 17β-hydroxysteroid dehydrogenase 4 (HSD17B4) is a novel… https://t.co/2a08317WWg #oncology

Nov 9, 2021 · 6,509 followers View post →