Dermatol Ther March 2022 PMID 34962033

The influence of benzoyl peroxide on skin microbiota and the epidermal barrier for acne vulgaris.

Lin Zhou, Lingna Chen, Xueping Liu, Yukun Huang, Yong Xu, Xia Xiong, Yongqiong Deng

Mentions

8
Peak: 2 in Dec 2021
across 4 sources since Dec 2021

Extended reach

98,973
potential audience

Total likes

1,871

Video views

90,671

Mentions per month

Dec 2021 – Sep 2025

Where it's discussed

  • X / Twitter3 posts
  • YouTube2 videos
  • News2 articles
  • Facebook1 posts

AI synopsis

What people are saying

Many discussions mention the dual nature of benzoyl peroxide's effects, with phrases like 'destroy your skin barrier' and 'decrease microbiome diversity', reflecting concerns about potential harm. The tone varies from cautionary to neutral, indicating a general awareness of the research's significance but limited deep engagement with the science or clinical implications.

AgreementModerate agreement

Most discussions acknowledge that benzoyl peroxide has both positive and negative effects, aligning with the article's findings that it improves acne but may harm the skin barrier and microbiome.

InterestModerate interest

The comments demonstrate moderate interest, highlighting potential risks and effects, but lack deep technical analysis,

EngagementModerate engagement

Discussions include cautionary advice and basic summaries, showing some engagement but without detailed exploration or extensive debate.

ImpactNeutral impact

While the posts recognize important implications for skincare, they don't seem to significantly influence or alter existing opinions on treatment practices.

Abstract in brief

  • Benzoyl peroxide (BPO) effectively improves acne symptoms and reduces the presence of certain bacteria like Cutibacterium on the skin, but it also decreases overall skin microbial diversity and may harm the skin's protective barrier.
  • Treatment with BPO increases skin hydration and water retention, indicating some positive effects on the epidermal barrier, yet it also raises transepidermal water loss, which suggests potential barrier damage.
  • The study suggests that while BPO helps control acne, it might also negatively impact the skin's microbiome and barrier function, highlighting the need for balanced skincare approaches.

Top posts

Most liked on X and Bluesky
Shankar Mundluru
@SMundluruPH · X

Did you know that benzoyl peroxide, a common treatment for acne, can destroy your skin barrier and decrease your skin microbiome diversity? try to avoid it if you can #phage #phagealternative https://t.co/DU8qNXHdBz

Mar 8, 2024 · 1 like · 9 followers View post →
Microbiome Articles
@microbe_article · X

The influence of benzoyl peroxide on skin microbiota and the epidermal barrier for acne vulgaris. - Zhou L et al. - https://t.co/GqMkWVjZfu #microbiome

Dec 29, 2021 · 7,160 followers View post →

All mentions

Shankar Mundluru
@SMundluruPH · X

Did you know that benzoyl peroxide, a common treatment for acne, can destroy your skin barrier and decrease your skin microbiome diversity? try to avoid it if you can #phage #phagealternative https://t.co/DU8qNXHdBz

Mar 8, 2024 · 1 like · 9 followers View post →
Microbiome Articles
@microbe_article · X

The influence of benzoyl peroxide on skin microbiota and the epidermal barrier for acne vulgaris. - Zhou L et al. - https://t.co/GqMkWVjZfu #microbiome

Dec 29, 2021 · 7,160 followers View post →
Symbiosis papers
@Symbiosispapers · X

The influence of benzoyl peroxide on skin microbiota and the epidermal barrier for acne vulgaris https://t.co/LdNZEdJZuB

Dec 28, 2021 · 1,104 followers View post →
Równowaga mikrobioty skóry w leczeniu trądziku – rola preparatów ...
News

Dermatol Ther 2022; 35: e15288. DOI: 10.1111/dth.15288. 15. Lam M, Hu A, Fleming P i wsp. The impact of acne treat- ment on skin bacterial microbiota: a ...

Jan 2, 2026 View →
Skin microbiota balance in acne treatment – the role of topical ...
News

Dermatol Ther 2022; 35: e15288. DOI: 10.1111/dth.15288. 15. Lam M, Hu A, Fleming P i wsp. The impact of acne treatment on skin bacterial ...

Sep 15, 2025 View →
賴宇凡- 本篇參考資料: Smythe P, Wilkinson HN. The Skin ...
Facebook

... e15288. doi: 10.1111/dth.15288. Epub 2022 Jan 18. PMID: 34962033. https://iris.who.int/bitstream/handle/10665/38140/924151101X-eng.pdf ...

May 16, 2025 View →