Cell Host Microbe February 2022 PMID 34998466

Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies.

Denise Haslwanter, Gorka Lasso, Anna Z Wec, Nathália Dias Furtado, Lidiane Menezes Souza Raphael, Alexandra L Tse, Yan Sun, Stephanie Stransky, Núria Pedreño-Lopez, Carolina Argondizo Correia, Zachary A Bornholdt, Mrunal Sakharkar, Vivian I Avelino-Silva, Crystal L Moyer, David I Watkins

Mentions

20
Peak: 7 in Apr 2022
across 3 sources since Aug 2021

Extended reach

206,243
potential audience

Total likes

13

Video views

375

Mentions per month

Aug 2021 – Oct 2025

Where it's discussed

  • X / Twitter10 posts
  • News8 articles
  • YouTube2 videos

AI synopsis

What people are saying

The analysis indicates general agreement on the importance of the findings, illustrated by mentions of the genetic differences affecting vaccine effectiveness, such as the emphasis on genotype-specific features and the potential need for revised vaccine strategies. The tone is factual and slightly supportive, with references to the study’s focus and hashtags highlighting key aspects like glycoprotein domains, indicating a recognition of the scientific impact while maintaining a neutral engagement level.

AgreementModerate agreement

Most discussions recognize the significance of the study, with some expressing support or agreement on the importance of understanding genotype-specific features affecting vaccine efficacy.

InterestModerate interest

The discussions show moderate interest, primarily through references to the study’s findings and relevance to vaccine development or disease control.

EngagementNeutral engagement

Participants seem to acknowledge the research but do not delve deeply into methodological details or broader implications, leading to a neutral engagement score.

ImpactModerate impact

Overall, users appear to consider the research noteworthy, suggesting it could influence future research directions or public health strategies, though this is not explicitly emphasized.

Abstract in brief

  • South American yellow fever virus strains show reduced susceptibility to vaccine-induced antibodies due to specific genetic differences, especially in the glycoprotein E.
  • These genetic changes, particularly in the protein's domain II, make current vaccines less effective against recent South American strains.
  • The study suggests that vaccine strategies might need to be updated and that current immunological surveillance approaches should be reevaluated for better protection in South America.]

Top posts

Most liked on X and Bluesky
Office of Science and Technology Austria
@OSTAustria_DC · X

Apr 14, 2022 · 5 likes · 4 shares · 2,278 followers View post →
Arbovirus News
@ArboNews · X

Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies https://t.co/Bwz3ywXogx

Jan 10, 2022 · 3 likes · 5,069 followers View post →
bioRxiv
@biorxivpreprint · X

Genotype-specific Features Reduce the Susceptibility of South American Yellow Fever Virus Strains to Vaccine-Induced Antibodies https://t.co/VvIwLQoEUU #bioRxiv

Aug 22, 2021 · 2 likes · 138,056 followers View post →
bioRxiv Microbiology
@biorxiv_micrbio · X

Genotype-specific Features Reduce the Susceptibility of South American Yellow Fever Virus Strains to Vaccine-Induced Antibodies https://t.co/pdxackHGe7 #biorxiv_micrbio

Aug 22, 2021 · 1 like · 1 share · 20,976 followers View post →
Office of Science and Technology Austria
@OSTAustria_DC · X

Apr 20, 2022 · 1 like · 2,278 followers View post →
Albert Einstein College of Medicine - Official
@EinsteinMed · X

RT @OSTAustria_DC:

Apr 14, 2022 · 4 shares · 32,323 followers View post →

All mentions

Office of Science and Technology Austria
@OSTAustria_DC · X

Apr 20, 2022 · 1 like · 2,278 followers View post →
EURAXESS North America
@EURAXESS_NA · X

RT @OSTAustria_DC:

Apr 15, 2022 · 4 shares · 2,585 followers View post →
ASCINA NYC
@ASCINA_NYC · X

RT @OSTAustria_DC:

Apr 14, 2022 · 4 shares · 192 followers View post →
Albert Einstein College of Medicine - Official
@EinsteinMed · X

RT @OSTAustria_DC:

Apr 14, 2022 · 4 shares · 32,323 followers View post →
Office of Science and Technology Austria
@OSTAustria_DC · X

Apr 14, 2022 · 5 likes · 4 shares · 2,278 followers View post →
Arbovirus News
@ArboNews · X

Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies https://t.co/Bwz3ywXogx

Jan 10, 2022 · 3 likes · 5,069 followers View post →
Phage Papers
@Phage_Papers · X

Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies https://t.co/9YxXNiqsCn

Jan 10, 2022 · 645 followers View post →
glycopreprint
@glycopreprint · X

Genotype-specific Features Reduce the Susceptibility of South American Yellow Fever Virus Strains to Vaccine-Induced Antibodies https://t.co/PDc0Xgjnzc #glycotime

Sep 1, 2021 · 1,352 followers View post →
bioRxiv Microbiology
@biorxiv_micrbio · X

Genotype-specific Features Reduce the Susceptibility of South American Yellow Fever Virus Strains to Vaccine-Induced Antibodies https://t.co/pdxackHGe7 #biorxiv_micrbio

Aug 22, 2021 · 1 like · 1 share · 20,976 followers View post →
bioRxiv
@biorxivpreprint · X

Genotype-specific Features Reduce the Susceptibility of South American Yellow Fever Virus Strains to Vaccine-Induced Antibodies https://t.co/VvIwLQoEUU #bioRxiv

Aug 22, 2021 · 2 likes · 138,056 followers View post →
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