Transcriptomes
@transcriptomes · X
Androgen receptor-mediated paracrine signaling induces regression of blood vessels in the der... https://t.co/bbsmjGtPCN
Jan 18, 2022 · 1,809 followers
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August 2022 PMID 35033537
Androgen Receptor-Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia.
Mentions
5
Peak: 1 in Jan 2022
across 2 sources since Jan 2022
Extended reach
83,574
potential audience
Total likes
2,138
Video views
81,765
Mentions per month
Jan 2022 – Nov 2025Where it's discussed
-
YouTube4 videos
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X / Twitter1 posts
AI synopsis
What people are saying
The overall sentiment reflects strong interest and support, exemplified by posts praising the discovery of AR's role in blood vessel regression and discussing potential early interventions. The tone and choice of words like 'game-changing' and 'new insights' underscore the perceived importance of the research, prompting deeper conversations about its potential applications.
AgreementModerate agreement
Most discussions acknowledge the significance of the research, with some explicitly supporting the findings and their implications for understanding hair loss.
InterestHigh interest
Posts demonstrate high curiosity in the topic, with many expressing enthusiasm about the mechanisms and potential treatments highlighted.
EngagementModerate engagement
Users actively analyze the study's methods and implications, referencing pathways and possible therapeutic strategies.
ImpactModerate impact
The discussions suggest the research could influence future treatments and prompt further studies into blood vessel regeneration and hair growth.
Abstract in brief
- The study finds that in men with androgenetic alopecia (AGA), the androgen receptor (AR) moves into the nucleus of cells in the dermal papilla (DP), which is crucial for hair growth, and this is linked to blood vessel regression within the DP.
- It shows that microvascular abnormalities and vessel regression happen early during hair follicle miniaturization in AGA, with blood vessels gathering around the DP during the initiation of a new hair growth cycle, indicating that blood vessel health is important for hair regeneration.
- The research reveals that AR signals through TGF pathways to cause apoptosis (cell death) of microvascular endothelial cells in the DP, leading to blood vessel regression, and suggests that early anti-AR treatments might be more effective in preventing or reversing hair loss.
Top posts
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Transcriptomes
@transcriptomes · X
Androgen receptor-mediated paracrine signaling induces regression of blood vessels in the der... https://t.co/bbsmjGtPCN
Jan 18, 2022 · 1,809 followers
View post →
No mentions from this source yet.