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The discussions frequently mention the improved transparency of newer antidepressant trials compared to older ones, highlighting concerns that around half of trials show no significant effect over placebo. Phrases like 'reporting bias remains a significant impediment' and 'it's not just conspiracy theory; it's basic marketing' reflect a critical tone that underscores the article's significance in the broader context of medical research integrity.
Many discussions reveal a consensus on the issues raised about selective publication, reflecting overall support for the study's findings.
The posts indicate a high level of curiosity, with participants actively seeking out information and discussing the implications of the study.
Numerous posts delve into the methodologies and historical context of the studies mentioned, showcasing a deep engagement with the article's details.
Participants emphasize the significant consequences of publication bias on scientific integrity and patient outcomes, indicating a strong belief in the importance of this research.
Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials https://t.co/K5M6QSDNid
@pssd_awareness @atomicaceso @ChrisGovernale @Inamadworld1 @shvogt @jill_d35 @kenjaques @PssdWarrior @ShillfieldTim @recover2renew @benzosarebad Turner, et al. (2022). Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials. PLOS Medicine, 19(1), e1003886. https://t.co/fhwdW0JrzW
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials https://t.co/SoiQP39QaF @Mad_In_America @cochranecollab @dirnagl @Strech_Da @NaudetFlorian
FDAに登録された試験のうち、ポジティブな結果は論文になるけど、ネガティブ思考な結果は論文になってないという報告。こういう論文の書き方もあるのねえ Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/HzyKLPbO4K https://t.co/akGz8urCdp
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials https://t.co/rUhepatwtk via @eturnermd1 & @And_Cipriani & @Toshi_FRKW & @yadevries & @Geointheworld @SameiHuda
Selective Publication of #Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/jYIlUpVINw
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In this video, we explore myths and truths about cholesterol and its link to heart disease. We highlight key findings on low-density lipoprotein cholesterol and its impact on mortality rates, addressing risk factors…
Sobre los ISRS y el sesgo de publicación: Turner EH, Matthews AM. Selective publication of antidepressant trials and its influence on apparent efficacy. NEJM. 2008
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials https://t.co/qOlXF7f4eA via @eturnermd1 et al
RT @Altostrata: @pssd_awareness @atomicaceso @ChrisGovernale @Inamadworld1 @shvogt @jill_d35 @kenjaques @PssdWarrior @ShillfieldTim @recove…
RT @Altostrata: @pssd_awareness @atomicaceso @ChrisGovernale @Inamadworld1 @shvogt @jill_d35 @kenjaques @PssdWarrior @ShillfieldTim @recove…
RT @Altostrata: @pssd_awareness @atomicaceso @ChrisGovernale @Inamadworld1 @shvogt @jill_d35 @kenjaques @PssdWarrior @ShillfieldTim @recove…
RT @Altostrata: @pssd_awareness @atomicaceso @ChrisGovernale @Inamadworld1 @shvogt @jill_d35 @kenjaques @PssdWarrior @ShillfieldTim @recove…
RT @Altostrata: @pssd_awareness @atomicaceso @ChrisGovernale @Inamadworld1 @shvogt @jill_d35 @kenjaques @PssdWarrior @ShillfieldTim @recove…
RT @Altostrata: @pssd_awareness @atomicaceso @ChrisGovernale @Inamadworld1 @shvogt @jill_d35 @kenjaques @PssdWarrior @ShillfieldTim @recove…
@elonmusk @TheRabbitHole84 @joerogan Turner, et al. (2022). Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials. PLOS Medicine, 19(1), e1003886. https://t.co/fhwdW0JrzW
RT @Altostrata: @pssd_awareness @atomicaceso @ChrisGovernale @Inamadworld1 @shvogt @jill_d35 @kenjaques @PssdWarrior @ShillfieldTim @recove…
@pssd_awareness @atomicaceso @ChrisGovernale @Inamadworld1 @shvogt @jill_d35 @kenjaques @PssdWarrior @ShillfieldTim @recover2renew @benzosarebad Turner, et al. (2022). Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials. PLOS Medicine, 19(1), e1003886. https://t.co/fhwdW0JrzW
RT @DBDouble: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses…
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials | PLOS Medicine https://t.co/hITcrdnjBj
RT @Nils_Sim: @GianGaleazzi @EikoFried @PloederlM @HengartnerMP @paola_DZN @RichardBentall @AllenFrancesMD @matthewrbroome @gikkos1 @PsychS…
RT @Nils_Sim: @GianGaleazzi @EikoFried @PloederlM @HengartnerMP @paola_DZN @RichardBentall @AllenFrancesMD @matthewrbroome @gikkos1 @PsychS…
RT @Nils_Sim: @GianGaleazzi @EikoFried @PloederlM @HengartnerMP @paola_DZN @RichardBentall @AllenFrancesMD @matthewrbroome @gikkos1 @PsychS…
@GianGaleazzi @EikoFried @PloederlM @HengartnerMP @paola_DZN @RichardBentall @AllenFrancesMD @matthewrbroome @gikkos1 @PsychSleepy @lisabortolotti @Mental_Elf This paper replicated that in antidepressant RCTs, 50% of the trials do not even have a significant effect over placebo on group level, even in those recent trials with an average sample size of 440 (in a paradigm that is biased in favour of the drug). https://t.co/eLDuzPQaJ6
@davethom18 @leocondra @atmoore1216 @barstoolsports The point is science gets falsified for years to the detriment of man, yet you chose to blindly believe it. You’re being narrow again. https://t.co/8gIifn6nnD
@IKSapereAude @VeritasLos @sonmuda @HeinzGHerzog3 Gerne bringe ich hier auch dieses recht aktuelle Paper ein, welches das selektive Einreichen von Studien der Zulassungsphase und dessen Auswirkungen beschreibt: https://t.co/i4v8o7gY5g
@deriamis @WillReidWeb @LieblichSam @BodhiWeaver It's not conspiracy theory. It's basic marketing. Published research is biased. You rarely see the negative studies. If you do, they've been spun as positives. https://t.co/3a9QwpNzjV
@lluaces @bmwiernik @dsquintana @eturnermd1 Turner et al., 2008 is of my favorite papers ever; @eturnermd1 has a great slide / gif that perfectly illustrates the punchline. And he’s got an updated version of the paper out last year: https://t.co/uM9vh9lxam
RT @FinasterideInfo: PAPER: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and…
PAPER: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials #antidepressants https://t.co/hfnpJ6PF28
RT @RevistaMFSamfyc: Publicación selectiva de ensayos con antidepresivos y su influencia sobre la eficacia aparente: comparaciones actualiz…
#PLOSMedicine: Selective publication of antidepressant trials and its influence on apparent efficacy https://t.co/XleYOg0k9P Reporting bias persists but appears to have diminished for newer, compared to older, antidepressants. Continued efforts are needed to further improve ...
Publicación selectiva de ensayos con antidepresivos y su influencia sobre la eficacia aparente: comparaciones actualizadas y metaanálisis de ensayos más recientes frente a los más antiguos https://t.co/oVMO2nEbFx PMID 35045113
@Fizzbw @johndrummond33 @psychgeist52 @Altostrata @jf_moore @PloederlM @markhoro No, most negative trials are not published (at least honestly, ie without dredging the data). You need to look at the assessments from drug regulator agencies like the FDA https://t.co/knbzv3j8DU https://t.co/a5dVC5f9Qj
RT @susan_bewley: It shouldn't be so hard to 'fix' something so bad for science & patients but "Reporting bias remains a significant impedi…
Zometeen mag ik bij @BNR toelichting geven op het onderzoek waaruit blijkt dat negatieve onderzoeksresultaten (bij antidepressiva) vaak niet gepubliceerd worden. https://t.co/nDdlz0KwMS
It shouldn't be so hard to 'fix' something so bad for science & patients but "Reporting bias remains a significant impediment to researchers and medical decision-makers" @TranspariMED @HealthWatchUK @mgtmccartney @rcpsych @Mental_Elf @NathanHodson @pash22 https://t.co/No03qZfsiH
RT @rincondesisifo: (PLoS Med) Sesgo de publicación en estudios con antidepresivos e impacto sobre la aparente eficacia https://t.co/G3ONCY…
In an earlier study, using FDA documents, the authors found that many negative antidepressant trials had been misreported or unpublished. In a new meta-analysis, they found less inflation of drug efficacy among newer antidepressants compared to older ones https://t.co/MfimDllRY7
RT @EvidentlyBetter: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-an…
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials https://t.co/tmh5k6Yvvw
RT @TranspariMED: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analy…
RT @TranspariMED: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analy…
RT @TranspariMED: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analy…
RT @TranspariMED: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analy…
Metanalisis y actualidad de los antidepresivos. https://t.co/fsJFZZGWmA
RT @TranspariMED: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analy…
RT @HengartnerMP: Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of…
RT @Luke_629: Selective Publication of #Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/jYIlUpVINw
RT @TranspariMED: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analy…
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials https://t.co/SoiQP39QaF @Mad_In_America @cochranecollab @dirnagl @Strech_Da @NaudetFlorian
RT @HengartnerMP: Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of…
RT @HengartnerMP: Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of…
RT @recover2renew: #PLOSMedicine: Selective publication of #antidepressant trials and its influence on apparent efficacy: Updated ... https…
RT @pash22: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of…
RT @OxPsychiatry: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analy…
RT @HengartnerMP: Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of…
RT @ArthurCaplan: #PLOSMedicine: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated ... https:/…
RT @ArthurCaplan: #PLOSMedicine: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated ... https:/…
#PLOSMedicine: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated ... https://t.co/37bATSfofl
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials https://t.co/pmhG21lNWi
RT @HengartnerMP: Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of…
Sesgo de reporte por la no publicación de estudios negativos en antidepresivos sigue siendo un problema pero parece haber mejorado. https://t.co/WODjWBX3OZ
RT @HengartnerMP: Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of…
RT @HengartnerMP: Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of…
RT @HengartnerMP: Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of…
RT @HengartnerMP: Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of…
Update of Erick‘s @eturnermd1 seminal paper on selective reporting in antidepressant trials! Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials https://t.co/K5M6QSDNid
Andy Vermaut shares:Selective publication of antidepressant trials and its influence on apparent efficacy:… https://t.co/7uPwHLCg0T Thank you. #AndyVermautSharesThisNewsWithLoveAndHopes #TheWorldCanBecomeABetterPlaceSomedaySometime #WeNeedMoreLoveForWorldPeaceNowAndAlways
Selective Publication of #Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/jYIlUpVINw
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials https://t.co/b2XpCQ8kBa
RT @pash22: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of…
RT @pash22: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of…
RT @pash22: Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of…
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials https://t.co/rUhepatwtk via @eturnermd1 & @And_Cipriani & @Toshi_FRKW & @yadevries & @Geointheworld @SameiHuda
Well, enough for now. For more detail, once again, the link to the paper is https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003886#sec018
Out today in PLOS Medicine: Our update on publication bias with antidepressants. https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003886 Many many thanks to co-authors @yadevries @Toshi_FRKW @And_Cipriani @Geointheworld Brief recap here
#PLOSMedicine: Selective publication of #antidepressant trials and its influence on apparent efficacy: Updated ... https://t.co/NbBmbgsyqS
Selective publication of antidepressant trials and its influence on apparent efficacy https://t.co/oDpofZ8427
También: Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R. Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med 2008; 358(3): 252-260
Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/KkacwgVrdE
Selective publication of antidepressant trials and its influence on apparent efficacy - PubMed https://t.co/qzMlaQeKaM
RT @Bfd_Psych_Drugs: Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/LPcqlfYFRs
RT @Bfd_Psych_Drugs: Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/LPcqlfYFRs
Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/LPcqlfYFRs
Among 74 FDA-registered studies, 31%, accounting for 3449 study participants, were not published. @drfahrettinkoca Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/Bu2JjT9ZPl
Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/Rb4WhJ97hi
Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/Z1iTk0ymWV https://t.co/NtQMEONT3i
Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/7BAc0GlvGv
Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy https://t.co/LiGocvwbu4
Selective Publication of #Antidepressant Trials and Its Influence on Apparent Efficacy | @NEJM https://t.co/NRq57rSco0
Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/dlCpW7k4pw
@eturnermd1 @JSto A classic. Selective publication of #antidepressant trials and its influence on apparent efficacy. https://t.co/fOTJo6am1m "Selective reporting of clinical trial results may have adverse consequences for researchers, study participants, health care professionals, and patients."
@asaplsnr -> Andra har påvisat samma sak i andra system. Bäst och mest ihärdigt av @eturnermd1 i USA: Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy https://t.co/BYOxIKRHhD ->
RT @TFujiwarbi: FDAに登録された試験のうち、ポジティブな結果は論文になるけど、ネガティブ思考な結果は論文になってないという報告。こういう論文の書き方もあるのねえ Selective Publication of Antidepressant Trials a…
RT @TFujiwarbi: FDAに登録された試験のうち、ポジティブな結果は論文になるけど、ネガティブ思考な結果は論文になってないという報告。こういう論文の書き方もあるのねえ Selective Publication of Antidepressant Trials a…
FDAに登録された試験のうち、ポジティブな結果は論文になるけど、ネガティブ思考な結果は論文になってないという報告。こういう論文の書き方もあるのねえ Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy | NEJM https://t.co/HzyKLPbO4K https://t.co/akGz8urCdp
Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy https://t.co/f4AJSGv3Kx