Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism in the First Year of Therapy.
The discussions express strong agreement with the findings, especially noting that high hematocrit levels (>52%) pose increased risks, as seen in phrases like 'danger' and 'must consider.' The tone is serious and clinical, often highlighting implications for patient safety and practice adjustments, which underscores the high interest and impact in the message.
AgreementModerate agreement
Many posts acknowledge the study's findings and emphasize the increased risks associated with polycythemia during testosterone therapy.
InterestHigh interest
Posts demonstrate high engagement with the topic, referencing specific risk factors and clinical implications.
EngagementModerate engagement
Discussions include practical advice, referencing clinical management like dose reduction and phlebotomy, indicating active involvement.
ImpactHigh impact
The groups acknowledge that the study's insights could influence clinical practices and patient safety protocols, reflecting significant impact.
Abstract in brief
This study examined whether men receiving testosterone therapy (TT) who develop secondary polycythemia (high hematocrit levels) are at increased risk of serious heart and blood clot events in the first year of treatment.
Researchers used a large database to compare men on TT who developed polycythemia with those who did not, finding that those with polycythemia had a significantly higher risk of major adverse cardiovascular events (MACE) and venous thromboembolism (VTE).
The findings suggest that developing polycythemia during TT is an independent risk factor for serious health risks, highlighting the need for future studies to consider hematocrit levels when evaluating TT safety.
"Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events & Venous Thromboembolism in the 1st Year of Therapy"
Full Journal: https://t.co/v4Ys6giDrj
Authored by: @SirpiNackeeran, @ranjithramamd, & more https://t.co/4n71ljUzbZ
Feb 21, 2022 · 24 likes · 6 shares · 41,675 followersView post →
JU
Journal of Urology
@JUrology · X
"Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism in the First Year of Therapy"
Full Journal ➡️ https://t.co/cHFKywxXUX
Authored by: @jesse_ory, @SirpiNackeeran, @ranjithramamd, & MORE
Feb 15, 2022 · 17 likes · 2 shares · 41,675 followersView post →
JU
Journal of Urology
@JUrology · X
"Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism in the 1st Year of Therapy"
May 24, 2022 · 14 likes · 4 shares · 41,675 followersView post →
S
SMSNA
@SMSNA_ORG · X
In the 1st yr of #TRT, secondary polycythemia appears to increase risk of major adverse CVE and VTE. #testosterone https://t.co/Fdrlg90ypk
Feb 7, 2022 · 8 likes · 4 shares · 4,371 followersView post →
JB
Jonathan Beilan
@JonBeilan · X
A worthy read for any #testosterone -rx'ing clinician. Take home message: Polycythemia secondary to TRT in the 1st year of therapy can increase the risk of MACE/VTE in these pts.
>52% Hct = danger
Consider dose reduction +/- therapeutic phlebotomy
https://t.co/u8jit0vwaP
Aug 8, 2022 · 4 likes · 1 share · 941 followersView post →
GE
Giray Ergin
@gerginuro · X
Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism in the First Year of Therapy | Journal of Urology https://t.co/oWkfvr7gle
This video discusses how testosterone therapy can cause secondary polycythemia, increasing the risk of serious cardiovascular events and blood clots. It explains how to manage elevated red blood cell counts during TRT…
This discussion covers the pros and cons of TRT, including potential risks like atrial fibrillation, kidney injury, and blood pressure changes, based on recent studies. It explores different administration methods and…
If you’re on TRT or considering it, do it under the guidance of an experienced provider! They can monitor for adverse effects and adjust treatment if needed. Link to study: https://t.co/g2DAjZa3bQ
A worthy read for any #testosterone -rx'ing clinician. Take home message: Polycythemia secondary to TRT in the 1st year of therapy can increase the risk of MACE/VTE in these pts.
>52% Hct = danger
Consider dose reduction +/- therapeutic phlebotomy
https://t.co/u8jit0vwaP
Aug 8, 2022 · 4 likes · 1 share · 941 followersView post →
SM
Saeid Shamsian MD
@evarellcorp · X
Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism in the First Year of Therapy | Journal of Urology - MashupMD https://t.co/CvFdvMNlvS
RT @JUrology: "Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venou…
May 24, 2022 · 4 shares · 343 followersView post →
JO
Jesse Ory
@jesse_ory · X
RT @JUrology: "Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venou…
May 24, 2022 · 4 shares · 290 followersView post →
AA
Amer. Urol. Assn.
@AmerUrological · X
RT @JUrology: "Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venou…
May 24, 2022 · 4 shares · 46,824 followersView post →
JM
Jonathan Pavlinec, MD
@jpavs17 · X
RT @JUrology: "Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venou…
May 24, 2022 · 4 shares · 686 followersView post →
JU
Journal of Urology
@JUrology · X
"Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism in the 1st Year of Therapy"
May 24, 2022 · 14 likes · 4 shares · 41,675 followersView post →
MH
Maurício Hachul
@mauriciohachul · X
Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism in the First Year of Therapy | Journal of Urology https://t.co/ONM2gQ0eUP
@Bloodman @aoglasser @BobbieJeanSwei1 Just found this too-chart came to me today so THANK YOU for your input on this. Now for proper timing of holding preop testosterone - harder as pts don't want to stop, but DVT risk (mostly total joint patients) must be regarded with proper consideration. https://t.co/empcOvmgce
RT @JUrology: "Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events & Venous…
Feb 21, 2022 · 6 shares · 684 followersView post →
SM
Sirpi Nackeeran, MD, MPH
@SirpiNackeeran · X
RT @JUrology: "Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events & Venous…
Feb 21, 2022 · 6 shares · 343 followersView post →
LD
Luis A. Morales Ojeda, M.D
@DrLuismorales90 · X
RT @JUrology: "Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events & Venous…
Feb 21, 2022 · 6 shares · 438 followersView post →
JU
Journal of Urology
@JUrology · X
"Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events & Venous Thromboembolism in the 1st Year of Therapy"
Full Journal: https://t.co/v4Ys6giDrj
Authored by: @SirpiNackeeran, @ranjithramamd, & more https://t.co/4n71ljUzbZ
Feb 21, 2022 · 24 likes · 6 shares · 41,675 followersView post →
SM
Saeid Shamsian MD
@evarellcorp · X
Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism in the First Year of Therapy | Journal of Urology - MashupMD https://t.co/hcsN3S4fcm
"Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism in the First Year of Therapy"
Full Journal ➡️ https://t.co/cHFKywxXUX
Authored by: @jesse_ory, @SirpiNackeeran, @ranjithramamd, & MORE
Feb 15, 2022 · 17 likes · 2 shares · 41,675 followersView post →
S
SMSNA
@SMSNA_ORG · X
In the 1st yr of #TRT, secondary polycythemia appears to increase risk of major adverse CVE and VTE. #testosterone https://t.co/Fdrlg90ypk
Feb 7, 2022 · 8 likes · 4 shares · 4,371 followersView post →
GE
Giray Ergin
@gerginuro · X
Secondary Polycythemia in Men Receiving Testosterone Therapy Increases Risk of Major Adverse Cardiovascular Events and Venous Thromboembolism in the First Year of Therapy | Journal of Urology https://t.co/oWkfvr7gle