January 2022 PMID 35059607

Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease.

Katharina Hopp, Victoria A Catenacci, Nidhi Dwivedi, Timothy L Kline, Wei Wang, Zhiying You, Dustin T Nguyen, Kristen Bing, Bhavya Poudyal, Ginger C Johnson, Matthew R Jackman, Marsha Miller, Cortney N Steele, Natalie J Serkova, Paul S MacLean

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Mentions

13
Peak: 7 in Jan 2022
across 2 sources since Jan 2022

Extended reach

21,471
potential audience

Total likes

73

Video views

3,779

Mentions per month

Jan 2022 – Mar 2024

Where it's discussed

  • X / Twitter11 posts
  • YouTube2 videos

AI synopsis

What people are saying

The comments reflect a balanced perspective, with some posters emphasizing the potential benefits of caloric restriction for ADPKD, such as comments about the importance of clinical trials and the controversy around preclinical data. The tone combines curiosity with caution, suggesting moderate engagement and acknowledgment of the research's significance without overstatement, evident in phrases like 'clinical trials are essential' and 'preclinical data is controversial.'

AgreementModerate agreement

Most discussions acknowledge the importance of clinical trials and cautious interpretation of the preclinical findings, showing general agreement with the cautious tone.

InterestModerate interest

The topics of weight loss and cystic disease progression are of moderate interest, with many posts sharing the article and emphasizing its relevance to kidney disease management.

EngagementModerate engagement

Posts include references to specific research, sharing links and advocating for further exploration, demonstrating a moderate level of engagement.

ImpactModerate impact

The discussions highlight potential clinical implications, though with caution, indicating a recognition of its possible influence but not asserting it as definitive.

Abstract in brief

  • Progression of autosomal dominant polycystic kidney disease (ADPKD) can be influenced by metabolic factors such as obesity, and reducing food intake shows promise in slowing cyst growth based on rodent studies.
  • A study with overweight or obese ADPKD patients found that daily caloric restriction (DCR) led to significant weight loss and better adherence compared to intermittent fasting (IMF).
  • In a mouse model of ADPKD, only those on DCR experienced significant weight loss and reduced cyst growth, suggesting that caloric restriction may be a beneficial treatment approach for managing ADPKD.

Top posts

Most liked on X and Bluesky
Int'l Society of Renal Nutrition and Metabolism
@ISRNM_Social · X

Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease https://t.co/N94L2RFfrn

Jan 19, 2022 · 12 likes · 4 shares · 1,782 followers View post →
PKD Research Resource Consortium
@PkdResearch · X

Check out this paper on "Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease"https://t.co/0oVq8Z7kK9 #endPKD #PolycysticKidneyDisease #kidneydisease

Feb 2, 2022 · 2 likes · 1 share · 536 followers View post →
iScience journal
@iScience_CP · X

Online now: Weight Loss and Cystic Disease Progression in Autosomal Dominant Polycystic Kidney Disease https://t.co/uxSKMrhZdR

Feb 10, 2022 · 1 like · 8,660 followers View post →
Katharina Hopp
@KatharinaHopp85 · X

@CKJsocial Agreed, clinical trials are essential prior advising PKD patients to modify amount, timing, or composition of caloric intake. Especially since the preclinical data is controversial, at least in respect to the efficacy of caloric intake timing (TRF, https://t.co/WvfsnbzXpl)

Apr 22, 2022 · 1 like · 269 followers View post →
soda_troubles,https://med-mastodon.com/@haysam
@set_fortess · X

RT @PkdResearch: Check out this paper on "Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease"https:…

Feb 2, 2022 · 1 share · 2,550 followers View post →
Adipose Papers
@adipose_papers · X

Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease https://t.co/AeI93j129i https://t.co/2xPnde7y8h

Jan 21, 2022 · 2,453 followers View post →

All mentions

Katharina Hopp
@KatharinaHopp85 · X

@CKJsocial Agreed, clinical trials are essential prior advising PKD patients to modify amount, timing, or composition of caloric intake. Especially since the preclinical data is controversial, at least in respect to the efficacy of caloric intake timing (TRF, https://t.co/WvfsnbzXpl)

Apr 22, 2022 · 1 like · 269 followers View post →
iScience journal
@iScience_CP · X

Online now: Weight Loss and Cystic Disease Progression in Autosomal Dominant Polycystic Kidney Disease https://t.co/uxSKMrhZdR

Feb 10, 2022 · 1 like · 8,660 followers View post →
soda_troubles,https://med-mastodon.com/@haysam
@set_fortess · X

RT @PkdResearch: Check out this paper on "Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease"https:…

Feb 2, 2022 · 1 share · 2,550 followers View post →
PKD Research Resource Consortium
@PkdResearch · X

Check out this paper on "Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease"https://t.co/0oVq8Z7kK9 #endPKD #PolycysticKidneyDisease #kidneydisease

Feb 2, 2022 · 2 likes · 1 share · 536 followers View post →
ACHS Research
@AchsResearch · X

New NUTRITION Research Available. Click Here to Access Article(s): https://t.co/PMPtueChFT

Jan 24, 2022 · 44 followers View post →
Adipose Papers
@adipose_papers · X

Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease https://t.co/AeI93j129i https://t.co/2xPnde7y8h

Jan 21, 2022 · 2,453 followers View post →
Nutrióloga Jessica Pérez
@nutriJesssica · X

RT @ISRNM_Social: Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease https://t.co/N94L2RFfrn

Jan 19, 2022 · 4 shares · 766 followers View post →
Delmy Rodríguez
@DelmyRodrguez3 · X

RT @ISRNM_Social: Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease https://t.co/N94L2RFfrn

Jan 19, 2022 · 4 shares · 299 followers View post →
Fabiana Baggio Nerbass
@FabianaNerbass · X

RT @ISRNM_Social: Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease https://t.co/N94L2RFfrn

Jan 19, 2022 · 4 shares · 183 followers View post →
Aljosa Kuzmanovski
@Aljoo5 · X

RT @ISRNM_Social: Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease https://t.co/N94L2RFfrn

Jan 19, 2022 · 4 shares · 108 followers View post →
Int'l Society of Renal Nutrition and Metabolism
@ISRNM_Social · X

Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease https://t.co/N94L2RFfrn

Jan 19, 2022 · 12 likes · 4 shares · 1,782 followers View post →