JCO Precis Oncol January 2022 PMID 35085007

Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor Kinase Fusion-Positive Lung Cancers.

Alexander Drilon, Daniel S W Tan, Ulrik N Lassen, Serge Leyvraz, Yongmei Liu, Jyoti D Patel, Lee Rosen, Benjamin Solomon, Ricarda Norenberg, Laura Dima, Nicoletta Brega, Lin Shen, Victor Moreno, Shivaani Kummar, Jessica J Lin

Mentions

115
Peak: 68 in Jan 2022
across 4 sources since Jul 2021

Extended reach

469,621
potential audience

Total likes

309

Video views

14

Mentions per month

Jul 2021 – May 2025

Where it's discussed

  • X / Twitter108 posts
  • News4 articles
  • Bluesky2 posts
  • YouTube1 videos

AI synopsis

What people are saying

Several discussions highlight the impressive results reported, such as the 73% overall response rate and the well-tolerated nature of larotrectinib. The use of phrases like 'needle in a haystack, but if you find it - it’s a golden needle' indicates a strong appreciation for the drug's potential, while references to conferences underscore the excitement and importance of the findings in the medical community.

AgreementStrong agreement

The majority of discussions reflect strong support for the findings of the publication, indicating consensus among many participants.

InterestHigh interest

There is a high level of curiosity, as many participants express enthusiasm towards the advances in treating TRK fusion-positive lung cancers.

EngagementModerate engagement

While some discussions delve into specifics regarding methodology and results, the overall engagement is moderate, showing some depth but not extensive.

ImpactHigh impact

Participants generally perceive the publication as having a significant impact on treatment options and patient care in oncology.

Abstract in brief

  • Larotrectinib is an effective and selective treatment for lung cancers with TRK gene fusions, showing a high objective response rate among patients.
  • The study analyzed data from two major clinical trials, which reported a 73% response rate in evaluable patients, with some achieving complete and partial responses.
  • The drug demonstrated favorable long-term safety and significant survival benefits, especially in patients with CNS metastases, highlighting the importance of testing for TRK fusions in lung cancer patients.

Top posts

Most liked on X and Bluesky
Jarushka Naidoo
@DrJNaidoo · X

Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4mo; mOS 40.7mo NTRK may be a needle in a haystack, but if u find it- it’s a golden needle

Jan 30, 2022 · 196 likes · 49 shares · 11,321 followers View post →
Aakash Desai, MD, MPH, FASCO
@ADesaiMD · X

"Efficacy and Safety of #Larotrectinib in Patients With #TRK–Positive Lung Cancers" @JCOPO_ASCO @alexdrilon among 15 evaluable patients ORR: 73% mDOR: 33.9 months, mPFS: 35.4 months mOS: 40.7 months Good CNS activity @OncoAlert https://t.co/Qzhfyhj6XU https://t.co/Sr0gf37snL

Feb 2, 2022 · 29 likes · 8 shares · 6,420 followers View post →
JCO Precision Oncology
@JCOPO_ASCO · X

.@alexdrilon et al. report on first analysis of the efficacy & safety of larotrectinib in pts with TRK fusion–positive lung cancer from a registrational data set. ORR of 73% ub 15 evaluable pts w OS of 40.7 months. Larotrectinib was well tolerated. https://t.co/HoQ25G6mgw https://t.co/VgpIkLa9jM

Feb 4, 2022 · 28 likes · 8 shares · 5,314 followers View post →
Dipesh Uprety MD FACP
@DipeshUpretyMD · X

Safety and efficacy of Larotrectinib --> NTRK-fusion positive NSCLC cohort --> ORR 73% Md DOR 33.9 mo Md PFS 35.4 mo Md OS 40.7 months #LCSM @OncoAlert https://t.co/GOPqxbgHZi

Jan 31, 2022 · 21 likes · 8 shares · 1,622 followers View post →
Rami Manochakian MD, FASCO Cancer Education
@RManochakian · X

Feb 6, 2022 · 8 likes · 2 shares · 4,235 followers View post →
Dr. Iván R. González
@Dr_Ivanoncologo · X

An interesting review shows that the highly selective #TRK inhibitor #larotrectinib is active and well-tolerated in patients with TRK fusion-positive #lungcancers, including those with #SNC #metastases. https://t.co/LmgOkxSL2D https://t.co/w6jI7poYlL

Jun 23, 2022 · 7 likes · 5 shares · 4,203 followers View post →

All mentions

bibliotecahuvh.bsky.social
@bibliotecahuvh.bsky.social · Bluesky

Efficacy and safety of larotrectinib in patients with TRK fusion gastrointestinal cancer scientiasalut.gencat.cat/handle/11351... #ScientiaVH

May 23, 2025 View post →
bibliotecahuvh.bsky.social
@bibliotecahuvh.bsky.social · Bluesky

Efficacy and safety of larotrectinib in patients with TRK fusion gastrointestinal cancer www.sciencedirect.com/science/arti... #hvhebron #onco [Text complet]

Mar 13, 2025 View post →
Bayer Oncology Medical
@BayerOncMed · X

RT @MGHCancerCenter: #ASCO23 | Hall A | Sunday 8am CT Long-term Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor…

Jun 6, 2023 · 1 share · 1,218 followers View post →
Mass General Cancer Center
@MGHCancerCenter · X

#ASCO23 | Hall A | Sunday 8am CT Long-term Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor Kinase (TRK) Fusion Lung Cancer Jessica Lin, MD (@JessicaJLinMD) ➡️ https://t.co/I4j2RKV3WG @ASCO #MGCCatASCO23 https://t.co/OIbGxHfYrW

Jun 4, 2023 · 5 likes · 1 share · 9,447 followers View post →
Gessie Anne Lopes MD
@GessieAnneLopes · X

RT @JCOPO_ASCO:

May 30, 2023 · 2 shares · 1,219 followers View post →
Bayer Oncology Medical
@BayerOncMed · X

RT @JCOPO_ASCO:

May 23, 2023 · 2 shares · 1,218 followers View post →
JCO Precision Oncology
@JCOPO_ASCO · X

May 19, 2023 · 5 likes · 2 shares · 5,314 followers View post →
Eriseld Krasniqi
@KrasniqiEriseld · X

RT @Dr_Ivanoncologo: An interesting review shows that the highly selective #TRK inhibitor #larotrectinib is active and well-tolerated in pa…

Jun 24, 2022 · 5 shares · 643 followers View post →
drfeelgood
@drfeelgood049 · X

RT @Dr_Ivanoncologo: An interesting review shows that the highly selective #TRK inhibitor #larotrectinib is active and well-tolerated in pa…

Jun 24, 2022 · 5 shares · 128 followers View post →
Chiara CATANIA
@ChiaraCATANIA4 · X

RT @Dr_Ivanoncologo: An interesting review shows that the highly selective #TRK inhibitor #larotrectinib is active and well-tolerated in pa…

Jun 24, 2022 · 5 shares · 1,161 followers View post →
filippo masini
@filimasini · X

RT @Dr_Ivanoncologo: An interesting review shows that the highly selective #TRK inhibitor #larotrectinib is active and well-tolerated in pa…

Jun 23, 2022 · 5 shares · 770 followers View post →
PRECISION ONCOLOGY CONNECT
@PresOnc_Connect · X

#WCGIC2022 is approaching! 2nd July @ElenaGarralda will discuss the long-term efficacy and safety of #larotrectinib in patients with tropomyosin receptor kinase (TRK) fusion GI cancers #MedEd #NTRK #Oncology https://t.co/IpoHoMW09E

Jun 23, 2022 · 1 like · 1,601 followers View post →
International Lung Cancer Summit
@LungSummit · X

RT @Dr_Ivanoncologo: An interesting review shows that the highly selective #TRK inhibitor #larotrectinib is active and well-tolerated in pa…

Jun 23, 2022 · 5 shares · 2,741 followers View post →
Dr. Iván R. González
@Dr_Ivanoncologo · X

An interesting review shows that the highly selective #TRK inhibitor #larotrectinib is active and well-tolerated in patients with TRK fusion-positive #lungcancers, including those with #SNC #metastases. https://t.co/LmgOkxSL2D https://t.co/w6jI7poYlL

Jun 23, 2022 · 7 likes · 5 shares · 4,203 followers View post →
Vivek Subbiah, MD
@VivekSubbiah · X

RT @ADesaiMD: "Efficacy and Safety of #Larotrectinib in Patients With #TRK–Positive Lung Cancers" @JCOPO_ASCO @alexdrilon among 15 evaluab…

Jun 7, 2022 · 8 shares · 39,028 followers View post →
Lung Cancer Research Foundation
@lcrf_org · X

#ASCO22 – June 6, 2:11 PM CT, Hall D1, poster 12: former LCRF grantee Dr. Alexander Drilon will present a poster session on updated efficacy and safety of larotrectinib in patients with tropomyosin receptor kinase (TRK) fusion #lungcancer. https://t.co/QbXd5vao9o https://t.co/oWmoQZxnwd

Jun 5, 2022 · 3 likes · 10,905 followers View post →
MGH Thoracic Oncology
@MGHThoracicOnc · X

@alexdrilon @JessicaJLinMD Read the full study at: https://t.co/ghj3rXOWOi

Mar 7, 2022 · 2 likes · 1,663 followers View post →
Phillip Febbo, MD
@PhilFebboMD_CMO · X

While TRK inhibitors are a pan-cancer therapy for tumors with TRK fusions, this paper summarizes efficacy in fusion-positive lung cancer. PFS of 35 months and OS 41 months with good results also seen in patients with CNS mets. We should never miss these https://t.co/zaQ5hrQCPT

Feb 15, 2022 · 2 likes · 2,584 followers View post →
Suzanne MacMahon
@SuzanneMacmahon · X

RT @cancer_evolve: LUNG: in a small study of patients with advanced NTRK fusion positive tumours who had failed conventional therapy, the N…

Feb 14, 2022 · 1 share · 166 followers View post →
Cancer_Evolve
@cancer_evolve · X

LUNG: in a small study of patients with advanced NTRK fusion positive tumours who had failed conventional therapy, the NTRK inhibitor larotrectinib delivered ORR 73% for 15 patients treated, including 1 complete response. https://t.co/TT2PycaotL

Feb 14, 2022 · 1 like · 1 share · 370 followers View post →
Alfredo Addeo MD
@Alfdoc2 · X

RT @RManochakian:

Feb 6, 2022 · 2 shares · 2,870 followers View post →
Rami Manochakian MD, FASCO Cancer Education
@RManochakian · X

Feb 6, 2022 · 8 likes · 2 shares · 4,235 followers View post →
Eriseld Krasniqi
@KrasniqiEriseld · X

RT @dipeshuprety4: Safety and efficacy of Larotrectinib --> NTRK-fusion positive NSCLC cohort --> ORR 73% Md DOR 33.9 mo Md PFS 35.4 mo Md…

Feb 5, 2022 · 8 shares · 643 followers View post →
JCO Precision Oncology
@JCOPO_ASCO · X

.@alexdrilon et al. report on first analysis of the efficacy & safety of larotrectinib in pts with TRK fusion–positive lung cancer from a registrational data set. ORR of 73% ub 15 evaluable pts w OS of 40.7 months. Larotrectinib was well tolerated. https://t.co/HoQ25G6mgw https://t.co/VgpIkLa9jM

Feb 4, 2022 · 28 likes · 8 shares · 5,314 followers View post →
Hem-Onc Fellows Network
@HemOncFellows · X

RT @ADesaiMD: "Efficacy and Safety of #Larotrectinib in Patients With #TRK–Positive Lung Cancers" @JCOPO_ASCO @alexdrilon among 15 evaluab…

Feb 3, 2022 · 8 shares · 7,540 followers View post →
Eduard Centeno
@segol60 · X

RT @ADesaiMD: "Efficacy and Safety of #Larotrectinib in Patients With #TRK–Positive Lung Cancers" @JCOPO_ASCO @alexdrilon among 15 evaluab…

Feb 3, 2022 · 8 shares · 409 followers View post →
Dr. Birep Aygün
@genperisi · X

RT @ADesaiMD: "Efficacy and Safety of #Larotrectinib in Patients With #TRK–Positive Lung Cancers" @JCOPO_ASCO @alexdrilon among 15 evaluab…

Feb 3, 2022 · 8 shares · 13,719 followers View post →
cadranel jacques
@CadranelJ · X

RT @ADesaiMD: "Efficacy and Safety of #Larotrectinib in Patients With #TRK–Positive Lung Cancers" @JCOPO_ASCO @alexdrilon among 15 evaluab…

Feb 3, 2022 · 8 shares · 1,592 followers View post →
Marcelo Corassa, MD.
@MarceloCorassa · X

RT @ADesaiMD: "Efficacy and Safety of #Larotrectinib in Patients With #TRK–Positive Lung Cancers" @JCOPO_ASCO @alexdrilon among 15 evaluab…

Feb 2, 2022 · 8 shares · 1,650 followers View post →
Santhosh Ambika
@RenoHemonc · X

RT @ADesaiMD: "Efficacy and Safety of #Larotrectinib in Patients With #TRK–Positive Lung Cancers" @JCOPO_ASCO @alexdrilon among 15 evaluab…

Feb 2, 2022 · 8 shares · 4,055 followers View post →
Charles Ricordel
@C_Ricordel · X

RT @ADesaiMD: "Efficacy and Safety of #Larotrectinib in Patients With #TRK–Positive Lung Cancers" @JCOPO_ASCO @alexdrilon among 15 evaluab…

Feb 2, 2022 · 8 shares · 577 followers View post →
Aakash Desai, MD, MPH, FASCO
@ADesaiMD · X

"Efficacy and Safety of #Larotrectinib in Patients With #TRK–Positive Lung Cancers" @JCOPO_ASCO @alexdrilon among 15 evaluable patients ORR: 73% mDOR: 33.9 months, mPFS: 35.4 months mOS: 40.7 months Good CNS activity @OncoAlert https://t.co/Qzhfyhj6XU https://t.co/Sr0gf37snL

Feb 2, 2022 · 29 likes · 8 shares · 6,420 followers View post →
Eduardo Cronemberger
@educronemberger · X

RT @dipeshuprety4: Safety and efficacy of Larotrectinib --> NTRK-fusion positive NSCLC cohort --> ORR 73% Md DOR 33.9 mo Md PFS 35.4 mo Md…

Feb 1, 2022 · 8 shares · 232 followers View post →
Fundacja Alivia
@fundacja_alivia · X

RT @dipeshuprety4: Safety and efficacy of Larotrectinib --> NTRK-fusion positive NSCLC cohort --> ORR 73% Md DOR 33.9 mo Md PFS 35.4 mo Md…

Feb 1, 2022 · 8 shares · 2,248 followers View post →
cadranel jacques
@CadranelJ · X

RT @dipeshuprety4: Safety and efficacy of Larotrectinib --> NTRK-fusion positive NSCLC cohort --> ORR 73% Md DOR 33.9 mo Md PFS 35.4 mo Md…

Feb 1, 2022 · 8 shares · 1,592 followers View post →
Pasquale Pisapia
@PasqualePisapia · X

RT @dipeshuprety4: Safety and efficacy of Larotrectinib --> NTRK-fusion positive NSCLC cohort --> ORR 73% Md DOR 33.9 mo Md PFS 35.4 mo Md…

Feb 1, 2022 · 8 shares · 960 followers View post →
OncoAlert
@OncoAlert · X

RT @dipeshuprety4: Safety and efficacy of Larotrectinib --> NTRK-fusion positive NSCLC cohort --> ORR 73% Md DOR 33.9 mo Md PFS 35.4 mo Md…

Feb 1, 2022 · 8 shares · 40,179 followers View post →
Matthias Scheffler
@trnsltnl · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Feb 1, 2022 · 49 shares · 1,133 followers View post →
Ancel Julien, M.D.
@AncelJulienMD · X

RT @dipeshuprety4: Safety and efficacy of Larotrectinib --> NTRK-fusion positive NSCLC cohort --> ORR 73% Md DOR 33.9 mo Md PFS 35.4 mo Md…

Feb 1, 2022 · 8 shares · 308 followers View post →
filippo masini
@filimasini · X

RT @dipeshuprety4: Safety and efficacy of Larotrectinib --> NTRK-fusion positive NSCLC cohort --> ORR 73% Md DOR 33.9 mo Md PFS 35.4 mo Md…

Feb 1, 2022 · 8 shares · 770 followers View post →
Dipesh Uprety MD FACP
@DipeshUpretyMD · X

Safety and efficacy of Larotrectinib --> NTRK-fusion positive NSCLC cohort --> ORR 73% Md DOR 33.9 mo Md PFS 35.4 mo Md OS 40.7 months #LCSM @OncoAlert https://t.co/GOPqxbgHZi

Jan 31, 2022 · 21 likes · 8 shares · 1,622 followers View post →
4baseCare
@4baseCare · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 396 followers View post →
David Wise MD PhD
@DrDaveWise · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 323 followers View post →
Eriseld Krasniqi
@KrasniqiEriseld · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 643 followers View post →
уон
@yoh_tw · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 281 followers View post →
NTRKers
@NTRKers · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 889 followers View post →
Shahzeena Aslam
@ShahzeenaAslam · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 1,067 followers View post →
Pablo Merino
@pablomerinorios · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 222 followers View post →
Avishek Roy
@Aviavipshaapal · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 199 followers View post →
HG@4base
@HG4base1 · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 81 followers View post →
Sam Cox
@Sam_J_Cox · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 175 followers View post →
Elad Sharon
@EladSharonMD · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 3,872 followers View post →
Rafael Correa Cano MD, MSc.
@Rf_Correa · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 1,014 followers View post →
OncoAlert
@OncoAlert · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 40,179 followers View post →
Pembrolizumab
@LauCuapa · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 180 followers View post →
David Tamborero
@DavidTamborero · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 648 followers View post →
OncoClic
@OncoClic · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 430 followers View post →
Baricorcho
@Baricorcho · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 4,080 followers View post →
Ramón MD
@ramonphysician · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 335 followers View post →
Dr.Hendri Wiyono,SpP
@drhendriwiyono · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 381 followers View post →
Andrew Hong
@hongdrew · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 227 followers View post →
Cancer Watch
@Cancer_watch · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 72 followers View post →
teru.1101
@1101_teru · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 45 followers View post →
Brian Shields
@MrPug94 · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 4,267 followers View post →
Amin Nassar, MD
@AminNassarMD · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 1,926 followers View post →
drfeelgood
@drfeelgood049 · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 128 followers View post →
JC Resistance 2015
@deweyjaci76 · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 1,831 followers View post →
Christophe Massard
@drcmassard · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 2,118 followers View post →
Pete Blackman
@peteblackman · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 1,628 followers View post →
International Lung Cancer Summit
@LungSummit · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 2,741 followers View post →
Debapriya Mondal
@debonco · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 31, 2022 · 26 shares · 189 followers View post →
AMRANE Karim
@AMRANEKarim6 · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 73 followers View post →
Charles Ricordel
@C_Ricordel · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 577 followers View post →
filippo masini
@filimasini · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 770 followers View post →
Sheyda Abdullaeva
@SheydaDoc · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 108 followers View post →
Canary Global Inc.
@CanaryTech · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 31, 2022 · 49 shares · 899 followers View post →
Ming "Tommy" Tang
@tangming2005 · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 30, 2022 · 49 shares · 41,382 followers View post →
Nour A. Haidar
@nourhaidar4 · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 30, 2022 · 49 shares · 863 followers View post →
Timothy Chan
@GeneCollector · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 30, 2022 · 49 shares · 5,039 followers View post →
Pat Adams
@PathologyPat · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 30, 2022 · 49 shares · 1,514 followers View post →
Olivier Elemento
@ElementoLab · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 30, 2022 · 49 shares · 6,242 followers View post →
Carlos Salazar
@DrSalazarMejia · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 30, 2022 · 49 shares · 944 followers View post →
Andres F. Cardona
@AndresFCardonaZ · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 30, 2022 · 49 shares · 8,835 followers View post →
Seamus Cotter
@CotterSeamus · X

RT @DrJNaidoo: Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4…

Jan 30, 2022 · 49 shares · 679 followers View post →
Jarushka Naidoo
@DrJNaidoo · X

Larotrectinib in NTRK Fusion+ NSCLC: - 20 nsclc pts from 3 early ph trials - ORR 73% (1 CR, 10 PRs) - mDOR 33.9mo; PFS 35.4mo; mOS 40.7mo NTRK may be a needle in a haystack, but if u find it- it’s a golden needle

Jan 30, 2022 · 196 likes · 49 shares · 11,321 followers View post →
Bárbara Lafayette
@BabiLafayette · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 29, 2022 · 26 shares · 620 followers View post →
Marc Pujalte
@m_pujaltemartin · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 29, 2022 · 26 shares · 38 followers View post →
Dr Julia Kennedy
@DrJuliaKennedy1 · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 164 followers View post →
JCO Precision Oncology
@JCOPO_ASCO · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 5,314 followers View post →
Eduard Centeno
@segol60 · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 409 followers View post →
Elene Mariamidze
@EMariamidze · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 2,486 followers View post →
JessicaJLinMD
@JessicaJLinMD · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 1,841 followers View post →
Dr. Bivas Biswas
@DrBivas · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 850 followers View post →
David S. Hong MD
@DavidHongMD · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 3,638 followers View post →
Dr. Antonio Calles
@Tony_Calles · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 12,090 followers View post →
Jason van Leuven
@jason_leuven · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 704 followers View post →
GBOT Alerta
@GBOT_Alerta · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 744 followers View post →
OncoAlert
@OncoAlert · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 40,179 followers View post →
Charles Ricordel
@C_Ricordel · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 577 followers View post →
filippo masini
@filimasini · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 770 followers View post →
Ferreira Marion
@FerreiraMarion2 · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 28, 2022 · 26 shares · 189 followers View post →
Paperbirds_Oncology
@PaperbirdsO · X

New article: Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor Kinase Fusion-Positive Lung Cancers https://t.co/46qmuoiWJu #lungcancer #oncology https://t.co/NxaXaqT6DA

Jan 27, 2022 · 891 followers View post →
Andrew Hong
@hongdrew · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 27, 2022 · 26 shares · 227 followers View post →
Manju George MVSc PhD Rectal Cancer Survivor
@manjuggm · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 27, 2022 · 26 shares · 2,536 followers View post →
Dr Adam Januszewski
@AdamJanuszewski · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 27, 2022 · 26 shares · 1,045 followers View post →
Tara Herrmann, PhD
@TaraHerrmannPhD · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 27, 2022 · 26 shares · 1,972 followers View post →
Pete Blackman
@peteblackman · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 27, 2022 · 26 shares · 1,628 followers View post →
Pat Adams
@PathologyPat · X

RT @StephenVLiu: Update on larotrectinib in #NTRK+ NSCLC @JCOPO_ASCO. In 20pts with NSCLC and a TRK fusion treated with larotrectinib, RR 7…

Jan 27, 2022 · 26 shares · 1,514 followers View post →
OncLive.com
@OncLive · X

WATCH: @alexdrilon, of @sloan_kettering, discusses the efficacy and safety data of larotrectinib in patients with tropomyosin receptor kinase fusion-positive lung cancer that was presented at the World Cancer Lung Conference 2021 meeting. #WCLC21 #lcsm https://t.co/UJVXw0sH3u https://t.co/MHKK3XxL8u

Nov 29, 2021 · 1 like · 48,486 followers View post →
Manju George MVSc PhD Rectal Cancer Survivor
@manjuggm · X

SO-29: Efficacy and safety of larotrectinib in patients with tropomyosin receptor kinase (TRK) fusion-positive gastrointestinal (GI) cancer: an expanded dataset talk by Valentina Boni #WorldGI2021 @myESMO #CRCSM https://t.co/OArOi9Hg1w

Jul 2, 2021 · 2,536 followers View post →