BMJ Open Diabetes Res Care January 2022 PMID 35101924

Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like peptide-1 receptor agonists in the UK.

Tracey Weiss, Lingfeng Yang, Richard D Carr, Sampriti Pal, Baanie Sawhney, Robert Boggs, Swapnil Rajpathak, Kristy Iglay

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Mentions

36
Peak: 2 in Feb 2022
across 4 sources since Feb 2022

Extended reach

1,300,629
potential audience

Total likes

16,553

Video views

1,264,902

Mentions per month

Feb 2022 – Jun 2024

Where it's discussed

  • News27 articles
  • X / Twitter6 posts
  • Blogs2 articles
  • YouTube1 videos

AI synopsis

What people are saying

The discussions reflect a balanced acknowledgment of the study's findings, including comments like 'weight loss outcomes were less than expected' and references to patient adherence rates, with tone and word choice emphasizing real-world challenges, which demonstrates moderate agreement and engagement. The mention of clinical implications indicates a perceived meaningful impact on patient care and treatment strategies.

AgreementModerate agreement

Most discussions acknowledge that the study's findings highlight challenges with real-world adherence and weight loss outcomes, aligning with the article's conclusions.

InterestModerate interest

The posts show moderate interest, with some expressing curiosity about the actual adherence rates and clinical implications, though few delve deeply into the details.

EngagementModerate engagement

Participants reference the study's data, such as the percentage of patients achieving weight loss or discontinuing medication, indicating a reasonable level of engagement.

ImpactModerate impact

The discussions suggest that the article influences opinions about treatment effectiveness in real-world settings, emphasizing the importance of adherence and support in management strategies.

Abstract in brief

  • This study examined how patients with type 2 diabetes in the UK actually stick to and benefit from GLP1 receptor agonists, a medication known to promote weight loss in clinical trials, but real-world adherence and weight loss outcomes are not well understood.
  • Among 589 patients, about 54% achieved at least 5% weight loss at 12 and 24 months, but a significant portion discontinued the medication over time, with around 46-40% still adherent at these points.
  • The findings suggest that in real-life settings, fewer patients experience the weight-loss benefits seen in trials, possibly due to poor adherence, highlighting the need for additional patient support to improve long-term use of GLP1 receptor agonists.]

Top posts

Most liked on X and Bluesky
らいおん
@drlion1111 · X

◆GLP-1受容体作動薬の効果 イギリスで2型糖尿病患者(BMIの中央値は41.2)にGLP-1RAを投与をした研究。 5%以上減量した人の割合は、1年後には33.4%、2年後では43.5%であった。 「BMJ Open Diabetes Research & Care」2022年1月 https://t.co/FxWfgzZuHu

Nov 23, 2022 · 8 likes · 7,478 followers View post →
らいおん
@drlion1111 · X

@thanksevrybody1 イギリスでBMIも高い2型糖尿病患者さんへのGLP-1投与のデザインにはなりますが、 https://t.co/wlDs6AVpxS 5%以上減量した人の割合が1年後には33.4%、2年後では43.5%というデータがあります。 健常人でも長い期間の投与で少ない食事量に慣れる期間が必要なのではないかと考えてます。

Nov 23, 2022 · 5 likes · 7,478 followers View post →
Nick Krontiris
@nick_krontiris · X

Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like peptide-1 receptor agonists in the UK (open access) https://t.co/z4bcfWjd7t #MetabolicSyndrome #Obesity #Diabetes #InsulinResistance #weightloss

Feb 4, 2022 · 2 likes · 19,029 followers View post →
BMJ Open Diabetes Research & Care journal
@DiabetesRC · X

Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like peptide-1 receptor agonists in the UK

Jun 24, 2024 · 2 likes · 1,482 followers View post →
Jose Daniel Mosquera Lozano
@jdmosqueral · X

Menos de lo esperado por los ensayos clínicos. Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like ... https://t.co/3lvvKqcb48

Jun 13, 2022 · 232 followers View post →
CPRD_lit
@CPRD_lit · X

Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like peptide-1 receptor agonists in the UK https://t.co/s4NvajKeHb

Feb 1, 2022 · 28 followers View post →

All mentions

BMJ Open Diabetes Research & Care journal
@DiabetesRC · X

Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like peptide-1 receptor agonists in the UK

Jun 24, 2024 · 2 likes · 1,482 followers View post →
らいおん
@drlion1111 · X

◆GLP-1受容体作動薬の効果 イギリスで2型糖尿病患者(BMIの中央値は41.2)にGLP-1RAを投与をした研究。 5%以上減量した人の割合は、1年後には33.4%、2年後では43.5%であった。 「BMJ Open Diabetes Research & Care」2022年1月 https://t.co/FxWfgzZuHu

Nov 23, 2022 · 8 likes · 7,478 followers View post →
らいおん
@drlion1111 · X

@thanksevrybody1 イギリスでBMIも高い2型糖尿病患者さんへのGLP-1投与のデザインにはなりますが、 https://t.co/wlDs6AVpxS 5%以上減量した人の割合が1年後には33.4%、2年後では43.5%というデータがあります。 健常人でも長い期間の投与で少ない食事量に慣れる期間が必要なのではないかと考えてます。

Nov 23, 2022 · 5 likes · 7,478 followers View post →
Jose Daniel Mosquera Lozano
@jdmosqueral · X

Menos de lo esperado por los ensayos clínicos. Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like ... https://t.co/3lvvKqcb48

Jun 13, 2022 · 232 followers View post →
Nick Krontiris
@nick_krontiris · X

Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like peptide-1 receptor agonists in the UK (open access) https://t.co/z4bcfWjd7t #MetabolicSyndrome #Obesity #Diabetes #InsulinResistance #weightloss

Feb 4, 2022 · 2 likes · 19,029 followers View post →
CPRD_lit
@CPRD_lit · X

Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like peptide-1 receptor agonists in the UK https://t.co/s4NvajKeHb

Feb 1, 2022 · 28 followers View post →